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  1. Article ; Online: Corrigendum to "Zhang Y, Han X, Hu N, Huff AF, Gao F, Ren J. Akt2 knockout alleviates prolonged caloric restriction-induced change in cardiac contractile function through regulation of autophagy. [J Mol Cell Cardiol. 2014 Jun; 71:81-91. PMID: 24368095].

    Zhang, Yingmei / Han, Xuefeng / Hu, Nan / Huff, Anna F / Gao, Feng / Ren, Jun

    Journal of molecular and cellular cardiology

    2021  Volume 163, Page(s) 190–191

    Language English
    Publishing date 2021-12-06
    Publishing country England
    Document type Published Erratum
    ZDB-ID 80157-4
    ISSN 1095-8584 ; 0022-2828
    ISSN (online) 1095-8584
    ISSN 0022-2828
    DOI 10.1016/j.yjmcc.2021.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 426: Show issues Location:
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  2. Article: [Research progress of the regulatory role of autophagy in metabolic liver diseases].

    Li, Y X / Ren, F / Chen, Y

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2023  Volume 31, Issue 1, Page(s) 105–108

    Abstract: Autophagy is one of several hepatic metabolic processes in which starved cells are supplied with glucose, free fatty acids, and amino acids to produce energy and synthesize new macromolecules. Moreover, it regulates the quantity and quality of ... ...

    Abstract Autophagy is one of several hepatic metabolic processes in which starved cells are supplied with glucose, free fatty acids, and amino acids to produce energy and synthesize new macromolecules. Moreover, it regulates the quantity and quality of mitochondria and other organelles. As the liver is a vital metabolic organ, specific forms of autophagy are necessary for maintaining liver homeostasis. Protein, fat, and sugar are the three primary nutrients that can be altered by different metabolic liver diseases. Drugs that have an effect on autophagy can either promote or inhibit autophagy, and as a result, it can either increase or inhibit the three major nutritional metabolisms that are affected by liver disease. Thus, this opens up a novel therapeutic option for liver disease.
    MeSH term(s) Humans ; Liver/metabolism ; Liver Diseases ; Autophagy ; Metabolic Diseases ; Mitochondria
    Language Chinese
    Publishing date 2023-02-16
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20201106-00601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cryptanshinone extract of Salvia miltiorrhiza stimulates pediatric acute myeloid leukemia stem cell apoptosis and the anti-inflammatory mechanism via accelerating microRNA-211-5p to supress Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway activation.

    Ye, Q / Ren, L / Jiang, Z M / Li, X Y / Wei, G Y / Ren, Y F / Ren, L H

    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

    2024  Volume 74, Issue 6

    Abstract: This study was designed to explore cryptanshinone (CPT) extract of Salvia miltiorrhiza stimulating pediatric acute myeloid leukemia (AML) stem cell (LSC) apoptosis and anti-inflammatory mechanism via accelerating microRNA (miR)-211-5p to restrain Janus ... ...

    Abstract This study was designed to explore cryptanshinone (CPT) extract of Salvia miltiorrhiza stimulating pediatric acute myeloid leukemia (AML) stem cell (LSC) apoptosis and anti-inflammatory mechanism via accelerating microRNA (miR)-211-5p to restrain Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathway activation. Obtaining blood samples from pediatric acute myeloid leukemia patients and healthy volunteers and detecting miR-211-5p and JAK2 were performed. Purchase of the human AML cell line KG1a was conducted, and sorting of KG1a cells was to gain LSC. Test of miR-211-5p and JAK2, the phosphorylation of JAK2/STAT3 was implemented. Pretreatment of LSCs was with CPT. Variation of miR-211-5p and JAK2 in LSCs was via plasmid transfection to explore their actions in cell advancement with apoptosis and inflammation. Identification of the targeting of miR-211-5p with JAK2 was implemented. In results: MiR-211-5p was declined in endometrial cancer, while JAK2 was elevated; CPT was available to boost LSC apoptosis and restrain the inflammation; elevated miR-211-5p or repressive JAK2 was available to strengthen the acceleration of CPT on LSCs apoptosis and the repression of inflammation; MiR-211-5p targeted JAK2; augmented JAK2 was available to turn around the action of elevated miR-211-5p. We conclude that CPT extract of Salvia miltiorrhiza stimulated pediatric LSC apoptosis and restrained the inflammation via accelerating microRNA (miR)-211-5p to suppress JAK2/STAT3 pathway activation.
    MeSH term(s) Child ; Humans ; Anti-Inflammatory Agents/pharmacology ; Apoptosis ; Cell Proliferation ; Inflammation ; Janus Kinase 2/metabolism ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Salvia miltiorrhiza/chemistry ; Signal Transduction ; STAT3 Transcription Factor/metabolism ; Stem Cells ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use
    Chemical Substances Anti-Inflammatory Agents ; Janus Kinase 2 (EC 2.7.10.2) ; MicroRNAs ; MIRN211 microRNA, human ; STAT3 Transcription Factor ; Plant Extracts
    Language English
    Publishing date 2024-02-07
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 1125221-2
    ISSN 1899-1505 ; 0867-5910 ; 0044-6033
    ISSN (online) 1899-1505
    ISSN 0867-5910 ; 0044-6033
    DOI 10.26402/jpp.2023.6.09
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1358: Show issues Location:
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  4. Article: [Prognostic nutritional index application value for acute-on-chronic liver failure co-infection].

    Wang, Y M / Liu, Y S / Li, J / Zhang, Q / Yan, T T / Ren, D F / Zhu, L / Zhang, G Y / Yang, Y / Liu, J F / Chen, T Y / Zhao, Y R / He, Y L

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2024  Volume 32, Issue 3, Page(s) 235–241

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Acute-On-Chronic Liver Failure/diagnosis ; Coinfection ; Nutrition Assessment ; Prognosis ; Hepatorenal Syndrome/complications ; Ascites/complications ; Retrospective Studies ; Hepatitis B virus ; ROC Curve
    Language Chinese
    Publishing date 2024-01-23
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20240109-00021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Retrospective analysis of perioperative anaphylactic shock induced by cefuroxime].

    Chen, M F / Zhang, J F / Ren, X L / Liu, Y / Huang, L

    Zhonghua nei ke za zhi

    2024  Volume 63, Issue 4, Page(s) 406–411

    Abstract: This study investigated the characteristics and frequency of perioperative anaphylactic shock induced by cefuroxime, so as to provide a reference for the safe and rational use of cefuroxime in the perioperative period. Cases of perioperative anaphylactic ...

    Abstract This study investigated the characteristics and frequency of perioperative anaphylactic shock induced by cefuroxime, so as to provide a reference for the safe and rational use of cefuroxime in the perioperative period. Cases of perioperative anaphylactic shock caused by cefuroxime in our hospital from 2011 to 2021 were extracted from the Adverse Drug Reaction Monitoring System. Literature reporting adverse drug reactions (ADR) including cefuroxime-induced anaphylactic shock in perioperative settings was collected from the CNKI, VIP, Wanfang, PubMed, and Web of Science databases from their respective inception to May 2022. Statistical analysis was performed for all cases of cefuroxime-induced perioperative anaphylactic shock. A total of 31 patients were included [13 men (48.1%) and 14 women (51.9%)], most of whom were over 60 years old (
    MeSH term(s) Male ; Humans ; Female ; Middle Aged ; Cefuroxime/adverse effects ; Anaphylaxis/chemically induced ; Anaphylaxis/complications ; Retrospective Studies ; Drug Hypersensitivity/etiology ; Skin Tests/adverse effects
    Chemical Substances Cefuroxime (O1R9FJ93ED)
    Language Chinese
    Publishing date 2024-04-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20231103-00293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Survey on the current situation and influencing factors of humanistic care ability of outpatient and emergency nurses in tertiary Grade A hospitals in Zhengzhou City].

    Ren, Y / Guo, S J / Guo, Y F / Zhu, R J / Zhao, P F

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2023  Volume 41, Issue 6, Page(s) 413–416

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Child ; Humans ; Outpatients ; Hospitals ; Employment ; Surveys and Questionnaires ; Nurses
    Language Chinese
    Publishing date 2023-07-03
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1050900-8
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.cn121094-20221012-00493
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    Zs.A 7219: Show issues Location:
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  7. Article ; Online: Wideband low-RCS and gain-enhanced antenna using frequency selective absorber based on patterned graphene.

    Wang, Fuwei / Wang, Yi / Zhang, Xiaoyu / Liu, Lu / Li, Ke / Ren, Yuhui

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 9306

    Abstract: ... band monostatic RCSs of the patch antenna. Meanwhile, due to the quasi-Fabry-Perot (F-P) effect ... the monostatic RCS from 1.32 to 17 GHz under y-polarization and from 1.4 to 16.8 GHz under x-polarization ...

    Abstract In this paper, a double-layer patterned graphene-based frequency-selective absorber (DGFSA) is proposed as a means of reducing an antenna's radar cross-section (RCS) while simultaneously increasing its gain. The antenna consists of a patch antenna with Multi-Graphene Frequency Selective Absorber (MGFSA) mounted on top. The DGFSA consists of double-layer patterned graphene and a band-pass frequency selective surface (FSS). Two patterned graphene lossy layers with different square resistances are used, which broaden the electromagnetic (EM) wave absorption bandwidth of the DGFSA, thus greatly reducing the out-band monostatic RCSs of the patch antenna. Meanwhile, due to the quasi-Fabry-Perot (F-P) effect, the gain of the proposed antenna is enhanced by 2.4 dB. Additionally, the low-RCS antenna reduces the monostatic RCS from 1.32 to 17 GHz under y-polarization and from 1.4 to 16.8 GHz under x-polarization, respectively. Furthermore, a decrease in the bistatic RCS is accomplished. Results from simulations and measurements match up nicely, which means the antenna we proposed has a good application on the stealth platform.
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-60143-1
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  8. Article ; Online: Cone beam computed tomography volumetric airway changes after orthognathic surgery: a systematic review.

    Steegman, R / Hogeveen, F / Schoeman, A / Ren, Y

    International journal of oral and maxillofacial surgery

    2022  

    Abstract: The aim of this systematic review was to provide a structured overview of three-dimensional airway volume changes in relation to various orthognathic surgeries. Clinical human studies performing pre- and postoperative three-dimensional airway volume ... ...

    Abstract The aim of this systematic review was to provide a structured overview of three-dimensional airway volume changes in relation to various orthognathic surgeries. Clinical human studies performing pre- and postoperative three-dimensional airway volume assessments to investigate volumetric changes of the airway after orthognathic surgery were included. Pre-determined inclusion and exclusion criteria were applied in an extensive search of the PubMed, Embase, and Web of Science electronic databases. The cut-off date was set to January 1, 2022. Forty-one articles reporting retrospective and prospective case-control and case series studies were included. All studies were determined to be of medium quality (moderate risk of bias). The included studies were categorized by type of intervention. Pre- and postoperative volumes were extracted from the available data, and volume changes as a percentage of the preoperative levels were calculated. Isolated mandibular setback surgery generally decreased the airway volume. Isolated maxillary or mandibular advancement, bimaxillary advancement, and surgically assisted maxillary expansion generally increased the airway volume in the total airway and oropharynx, among which the effect of bimaxillary advancement surgery appeared most significant. High heterogeneity exists in the terminology and definitions of the airway and its segments. A more uniform methodology for airway volume measurement is needed to provide an insight into the impact on the airway of specific types of surgical intervention. In conclusion, airway volumes are affected after orthognathic surgery, which may be of clinical significance, especially in patients who are predisposed to obstructive sleep apnoea.
    Language English
    Publishing date 2022-07-01
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 353721-3
    ISSN 1399-0020 ; 0901-5027
    ISSN (online) 1399-0020
    ISSN 0901-5027
    DOI 10.1016/j.ijom.2022.05.013
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  9. Article: [Two cases of potassium-aggravated myotonia induced by SCN4A gene variation].

    Zhang, Y J / Dai, L F / Ren, S S / Ding, C H

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2023  Volume 61, Issue 11, Page(s) 1043–1045

    MeSH term(s) Humans ; Myotonia Congenita/genetics ; Mutation ; NAV1.4 Voltage-Gated Sodium Channel/genetics
    Chemical Substances SCN4A protein, human ; NAV1.4 Voltage-Gated Sodium Channel
    Language Chinese
    Publishing date 2023-10-29
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20230731-00054
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    Zs.B 3292: Show issues Location:
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  10. Article: [The study of a key molecule Caspase-1 of inflammasome in hepatitis B virus-related diseases].

    Fan, Z H / Xu, L / Tian, Y / Cao, Y L / Zhang, X Y / Duan, Z P / Ren, F

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2023  Volume 30, Issue 11, Page(s) 1158–1162

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Hepatitis B virus/genetics ; Carcinoma, Hepatocellular/pathology ; Inflammasomes ; Cysteine Proteases ; Liver Neoplasms ; Hepatitis B, Chronic ; Acute-On-Chronic Liver Failure ; RNA, Messenger ; Caspases
    Chemical Substances Inflammasomes ; Cysteine Proteases (EC 3.4.-) ; RNA, Messenger ; Caspases (EC 3.4.22.-)
    Language Chinese
    Publishing date 2023-03-28
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20210512-00231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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