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Article ; Online: Deferred cord clamping to improve neonatal blood values: A systematic review and meta-analysis.

Zemouri, Charifa / Mestdagh, Eveline / Stiers, Mieke / Torfs, Kimberly / Kuipers, Yvonne

International journal of nursing studies

2024 Volume 153, Page(s) 104718

Abstract: Background: Practices related to umbilical cord clamping at birth should be evidence-based. Deferred cord clamping, compared to immediate cord clamping, shows benefits for preterm neonates but this may also apply to healthy term neonates. Different ... ...

Abstract	Background: Practices related to umbilical cord clamping at birth should be evidence-based. Deferred cord clamping, compared to immediate cord clamping, shows benefits for preterm neonates but this may also apply to healthy term neonates. Different blood sampling techniques are used to measure effect of deferred and immediate cord clamping. Objective: To assess the statistical and effect size differences between blood biomarkers from umbilical cord and capillary blood samples of healthy term neonates following either immediate or deferred cord clamping. Design: Systematic review and meta-analysis. Methods: The databases PubMed, Medline, CENTRAL, CINAHL and EMBASE were systematically searched. We included studies with a randomised clinical trial design comparing deferred and immediate cord clamping among healthy term neonates born by a spontaneous vaginal birth, reporting on blood biomarkers. Studies including caesarean births and premature births/neonates were excluded. Study attributes, sampling technique, blood biomarkers, mean differences, and standard deviations were extracted. The standardised mean differences (SMD) and sampling errors were calculated for effect size estimation. Meta-analyses were performed if ≥2 studies reported the same outcome using RevMan 5. Subgroup analyses distinguished effects from umbilical cord and capillary blood samples. Moderator tests and publication bias analyses were performed using JASP. Results: Fifteen studies were included for analysis. The biomarkers haematocrit, haemoglobin, and bilirubin were reported in ≥2 studies and thus eligible for pooling. No differences were found in haemoglobin (SMD -0.04, 95%CI -0.57 to 0.49) or bilirubin values (SMD 0.13, 95%CI -0.03 to 0.28) between umbilical cord blood samples collected after deferred or immediate cord clamping. Deferred cord clamping led to lower haematocrit values (SMD -0.3, 95%CI -0.53 to -0.07). Higher haematocrit (SMD 0.67, 95%CI 0.37 to 0.97) and haemoglobin values (SMD 0.76, 95%CI 0.56 to 0.97) from capillary blood samples, collected 2 to 72 h postpartum, showed when cord clamping was deferred. No effect was found on bilirubin values (SMD 0.13, 95%CI -0.03 to 0.28) irrespective of the sampling technique. Conclusions: Blood collected after deferred umbilical cord clamping showed increased haemoglobin and haematocrit values up to 72 h after birth, opposed to bilirubin values. Clinical evaluation of blood biomarkers from the umbilical cord shows different values compared to capillary blood. Sampling time and technique therefore seem essential in estimating the effects of deferred cord clamping. Tweetable abstract: This meta-analysis shows that sampling time and technique are essential in estimating the effects of deferred cord clamping on neonatal blood values.
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Journal Article
ZDB-ID	80148-3
ISSN	1873-491X ; 0020-7489
ISSN (online)	1873-491X
ISSN	0020-7489
DOI	10.1016/j.ijnurstu.2024.104718
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Article: The contribution of parity to ethnic differences in mothers' body mass index in the Netherlands: A Blinder-Oaxaca decomposition approach.

Çayci, Enise / Zemouri, Charifa / van den Broek, Thijs

Preventive medicine reports

2023 Volume 36, Page(s) 102484

Abstract: Women of Turkish and Moroccan origin in the Netherlands are relatively likely to have an unhealthy bodyweight. This study sheds light on how ethnic differences in parity, i.e., the number of times a female carried pregnancies to a viable gestational age, ...

Abstract	Women of Turkish and Moroccan origin in the Netherlands are relatively likely to have an unhealthy bodyweight. This study sheds light on how ethnic differences in parity, i.e., the number of times a female carried pregnancies to a viable gestational age, contribute to body mass index (BMI) differences between Turkish-born and Moroccan-born mothers aged 35 + and their native Dutch counterparts. We applied a Blinder-Oaxaca decomposition approach to pooled data from four migrant surveys based on national probability samples (n = 2,532). Unlike conventional mediation analyses, the Blinder-Oaxaca approach recognizes that the association between parity and bodyweight may vary across different groups. Our results indicated that Turkish-born and Moroccan-born mothers in the Netherlands had more children and a higher BMI than native Dutch mothers. Regression analyses moreover showed that the parity-BMI gradient was steeper for Turkish-born mothers than for native Dutch mothers. Decomposition using the Blinder-Oaxaca approach indicated that the higher number of children of Turkish-born and Moroccan-born mothers compared to native Dutch mothers contributed substantially to the higher mean BMI in the former groups. The steeper parity-BMI gradient in Turkish-born mothers further amplified the contribution of parity to the higher mean BMI of Turkish-born mothers as compared to native Dutch mothers. Future research is needed to assess to which extent the steep parity-BMI gradient in Turkish-born mothers can be explained by relatively strong barriers to a healthy lifestyle that Turkish-born mothers of a larger number of children may face due to a relatively strongly gendered division of household and childrearing tasks.
Language	English
Publishing date	2023-10-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	2785569-7
ISSN	2211-3355
ISSN	2211-3355
DOI	10.1016/j.pmedr.2023.102484
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Article ; Online: Trophic preferences of the pathogen Ralstonia solanacearum and consequences on its growth in xylem sap.

Baroukh, Caroline / Zemouri, Meriem / Genin, Stéphane

MicrobiologyOpen

2022 Volume 11, Issue 1, Page(s) e1240

Abstract: Ralstonia solanacearum is one of the most destructive pathogens worldwide. In the last 30 years, the molecular mechanisms at the origin of R. solanacearum pathogenicity have been studied in depth. However, the nutrition status of the pathogen once inside ...

Abstract	Ralstonia solanacearum is one of the most destructive pathogens worldwide. In the last 30 years, the molecular mechanisms at the origin of R. solanacearum pathogenicity have been studied in depth. However, the nutrition status of the pathogen once inside the plant has been poorly investigated. Yet, the pathogen needs substrates to sustain a fast-enough growth, maintain its virulence and subvert the host immunity. This study aimed to explore in-depth the xylem environment where the pathogen is abundant, and its trophic preferences. First, we determined the composition of tomato xylem sap, where fast multiplication of the pathogen occurs. Then, kinetic growth on single and mixtures of carbon sources in relation to this environment was performed to fully quantify growth. Finally, we calculated the concentration of available metabolites in the xylem sap flux to assess how much it can support bacterial growth in planta. Overall, the study underlines the adaptation of R. solanacearum to the xylem environment and the fact that the pathogen assimilates several substrates at the same time in media composed of several carbon sources. It also provides metrics on key physiological parameters governing the growth of this major pathogen, which will be instrumental in the future to better understand its metabolic behavior during infection.
MeSH term(s)	Biomass ; Kinetics ; Magnetic Resonance Spectroscopy ; Ralstonia solanacearum/growth & development ; Ralstonia solanacearum/pathogenicity ; Ralstonia solanacearum/physiology ; Stem Cells/physiology ; Xylem/chemistry ; Xylem/metabolism ; Xylem/microbiology
Language	English
Publishing date	2022-02-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2661368-2
ISSN	2045-8827 ; 2045-8827
ISSN (online)	2045-8827
ISSN	2045-8827
DOI	10.1002/mbo3.1240
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Article ; Online: Future directions for studying resilience of the oral ecosystem.

Zemouri, Charifa / Ofiteru, Irina Dana / Jakubovics, Nicholas S

British dental journal

2020 Volume 229, Issue 12, Page(s) 769–773

Abstract: The oral ecosystem is shaped by complex interactions between systemic health disease and the resident oral microbiota. Research in the last two decades has produced datasets describing the genetics and physiology of the host and the oral microbiome in ... ...

Abstract	The oral ecosystem is shaped by complex interactions between systemic health disease and the resident oral microbiota. Research in the last two decades has produced datasets describing the genetics and physiology of the host and the oral microbiome in health and disease. There are inter-individual differences in the ability to tolerate oral disease-promoting challenges. Identification of the key factors that drive a healthy and resilient oral ecosystem is urgently needed. So far, progress is being made towards replicating the host-microbiota interplay in vitro. Clinical studies may shed light on the mechanisms of oral health resilience. However, most clinical studies are cross-sectional and are insufficient for understanding resilience or for identifying biomarkers that correlate with the point of transition from oral health to dysbiosis. Mathematical and computational models, including artificial intelligence approaches, offer an opportunity to inform the design of clinical studies by identifying key biomarkers and interaction networks in complex datasets and predicting important parameters. This paper discusses some of the challenges and opportunities for understanding the biological basis of resilience of the oral ecosystem. It discusses the current status and challenges, and proposes a way forward to better understand resilience towards oral diseases.
MeSH term(s)	Artificial Intelligence ; Cross-Sectional Studies ; Dysbiosis ; Humans ; Microbiota ; Mouth Diseases
Language	English
Publishing date	2020-12-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218090-x
ISSN	1476-5373 ; 0007-0610
ISSN (online)	1476-5373
ISSN	0007-0610
DOI	10.1038/s41415-020-2407-8
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Article ; Online: Monkeypox: what do dental professionals need to know?

Zemouri, Charifa / Beltrán, Edgar O / Holliday, Richard / Jakubovics, Nicholas S / Allison, James R

British dental journal

2022 Volume 233, Issue 7, Page(s) 569–574

Abstract: Infection control is critical for the safe delivery of dental care. Infection control practices must be responsive to emerging and re-emerging infectious diseases and outbreaks, as was clearly seen during the peak of the COVID-19 pandemic. An emerging ... ...

Abstract	Infection control is critical for the safe delivery of dental care. Infection control practices must be responsive to emerging and re-emerging infectious diseases and outbreaks, as was clearly seen during the peak of the COVID-19 pandemic. An emerging global outbreak of the monkeypox virus has again raised potential challenges for infection control in dentistry. Monkeypox is an infectious disease, characterised by a rash affecting the skin and soft tissues, including the oral cavity. Previously, cases were mostly seen following contact with infected animals in Central and West Africa, with limited human-to-human transmission within and outside of these areas. However, since May 2022, sustained human-to-human transmission has occurred globally. Monkeypox can be transmitted via close contact with an infected person, contaminated objects and surfaces, or by droplets and possibly aerosols, which is therefore of potential importance to dental settings. This article discusses the relevance of monkeypox to dental professionals, the typical presentation of the disease, its potential impact on infection prevention and control practices and the delivery of dental services. The current monkeypox outbreak highlights the need for a more sustained programme of research into dental infection control that can provide a solid evidence base to underpin preparedness planning for future outbreaks and pandemics.
MeSH term(s)	Animals ; COVID-19/epidemiology ; Dentists ; Disease Outbreaks/prevention & control ; Humans ; Mpox (monkeypox)/epidemiology ; Mpox (monkeypox)/prevention & control ; Monkeypox virus ; Pandemics
Language	English
Publishing date	2022-10-14
Publishing country	England
Document type	Journal Article
ZDB-ID	218090-x
ISSN	1476-5373 ; 0007-0610
ISSN (online)	1476-5373
ISSN	0007-0610
DOI	10.1038/s41415-022-5079-8
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Article: Kruiscontaminatie: spatten, aerosolen en biofilm in de mondzorgpraktijk.

Laheij, A M G A / de Soet, J J / Crielaard, W / Zemouri, C / Volgenant, C M C

Nederlands tijdschrift voor tandheelkunde

2021 Volume 128, Issue 4, Page(s) 221–227

Abstract: During treatment in dental practices, drops of different sizes are produced (spats and aerosols). Microorganisms in these drops are of human origin or originate from the water in the dental unit. Therefore, these drops can contribute to cross ... ...

Title translation	Cross contamination: spatters, aerosols, and biofilm in dental practices.
Abstract	During treatment in dental practices, drops of different sizes are produced (spats and aerosols). Microorganisms in these drops are of human origin or originate from the water in the dental unit. Therefore, these drops can contribute to cross contamination in dental practices. Large drops settle quickly, while smaller drops can remain suspended in the air for a longer period of time. The highest level of contamination is found in the immediate vicinity of the source (the patient's mouth). Further away from the source and after stopping drop producing activities, the level of contamination in the air is comparable to control circumstances. Studies into the spread of viruses via this route in the dental practice have not yet been conducted. The risk of catching an infectious disease in the dental practice seems limited, but can be high in the case of a virulent microorganism, when the circumstances for spread of the virus are favorable, or if the recipient is immunocompromised.
MeSH term(s)	Aerosols ; Biofilms ; Humans
Chemical Substances	Aerosols
Language	Dutch
Publishing date	2021-04-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	603498-6
ISSN	0028-2200
ISSN	0028-2200
DOI	10.5177/ntvt.2021.04.20100
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Article ; Online: Heterogeneity in the efficacy of dental chemical disinfectants on water-derived biofilms

Zemouri, C / de Soet, J J / Volgenant, C M C / Crielaard, W / Laheij, A M G A

Biofouling

2020 Volume 36, Issue 5, Page(s) 587–596

Abstract: Conditions in dental unit waterlines are favourable for biofilm growth and contamination of dental unit water. The aim of this study was to assess the effect of several chemical disinfectants on bacteria in a biofilm model. Water-derived biofilms were ... ...

Abstract	Conditions in dental unit waterlines are favourable for biofilm growth and contamination of dental unit water. The aim of this study was to assess the effect of several chemical disinfectants on bacteria in a biofilm model. Water-derived biofilms were grown in a static biofilm model (Amsterdam Active Attachment model), using two growth media. Biofilms were challenged with Alpron/Bilpron, Anoxyl, Citrisil, Dentosept, Green & Clean, ICX and Oxygenal in shock dose and maintenance doses. The concentration and the composition of the chemical disinfectants influenced the number of culturable bacteria in the biofilms. The application of a single shock dose followed by a low dose of the same chemical disinfectants resulted in the greatest suppression of viable bacteria in the biofilms. Exposure to Citrisil and ICX consistently resulted in failure to control the biofilms, while Alpron/Bilpron had a substantial and relevant effect on the number of bacteria in the biofilms.
MeSH term(s)	Biofilms/drug effects ; Colony Count, Microbial ; Dental Equipment ; Disinfectants/pharmacology ; Equipment Contamination ; Water ; Water Microbiology
Chemical Substances	Disinfectants ; Water (059QF0KO0R)
Language	English
Publishing date	2020-06-25
Publishing country	England
Document type	Journal Article
ISSN	1029-2454
ISSN (online)	1029-2454
DOI	10.1080/08927014.2020.1782894
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Article: Intelligence artificielle : quel avenir en anatomie pathologique ?

Zemouri, Ryad / Devalland, Christine / Valmary-Degano, Séverine / Zerhouni, Noureddine

Annales de pathologie

2019 Volume 39, Issue 2, Page(s) 119–129

Abstract: Artificial Intelligence, in particular deep neural networks are the most used machine learning technics in the biomedical field. Artificial neural networks are inspired by the biological neurons; they are interconnected and follow mathematical models. ... ...

Title translation	Neural network: A future in pathology?
Abstract	Artificial Intelligence, in particular deep neural networks are the most used machine learning technics in the biomedical field. Artificial neural networks are inspired by the biological neurons; they are interconnected and follow mathematical models. Two phases are required: a learning and a using phase. The two main applications are classification and regression Computer tools such as GPU computational accelerators or some development tools such as MATLAB libraries are used. Their application field is vast and allows the management of big data in genomics and molecular biology as well as the automated analysis of histological slides. The Whole Slide Image scanner can acquire and store slides in the form of digital images. This scanning associated with deep learning algorithms allows automatic recognition of lesions through the automatic recognition of regions of interest previously validated by the pathologist. These computer aided diagnosis techniques are tested in particular in mammary pathology and dermatopathology. They will allow an efficient and a more comprehensive vision, and will provide diagnosis assistance in pathology by correlating several biomedical data such as clinical, radiological and molecular biology data.
MeSH term(s)	Artificial Intelligence ; Forecasting ; Humans ; Neural Networks, Computer ; Pathology/methods ; Pathology/trends
Language	French
Publishing date	2019-02-14
Publishing country	France
Document type	Journal Article
ZDB-ID	225720-8
ISSN	0242-6498
ISSN	0242-6498
DOI	10.1016/j.annpat.2019.01.004
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Article: Bioactive Compounds and In Vitro Antioxidant and Anticoccidial Activities of

Amrane-Abider, Meriem / Imre, Mirela / Herman, Viorel / Debbou-Iouknane, Nedjima / Zemouri-Alioui, Salima / Khaled, Souad / Bouiche, Cilia / Nerín, Cristina / Acaroz, Ulaș / Ayad, Abdelhanine

Biomedicines

2023 Volume 11, Issue 8

Abstract: The objective of the present study is to identify the biochemical compounds extracted from OFI flowers using ultra-high-performance liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry and to evaluate their in vitro ... ...

Abstract	The objective of the present study is to identify the biochemical compounds extracted from OFI flowers using ultra-high-performance liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry and to evaluate their in vitro antioxidant activities and anticoccidial effects on the destruction of
Language	English
Publishing date	2023-08-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines11082173
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Article ; Online: Coronavirus Disease 2019 in Newborns and Very Young Infants: a Series of Six Patients in France.

Meslin, Pauline / Guiomard, Clara / Chouakria, Mouna / Porcher, Julie / Duquesne, Frédérique / Tiprez, Catherine / Zemouri, Neila

The Pediatric infectious disease journal

2020 Volume 39, Issue 7, Page(s) e145–e147

Abstract: We present here a series of 6 infants hospitalized for coronavirus disease 2019 infection from March 14 to March 30, 5 of them are newborns. All 6 patients presented with fever, it was the main symptom for all of them. Only one of them needed oxygen; the ...

Abstract	We present here a series of 6 infants hospitalized for coronavirus disease 2019 infection from March 14 to March 30, 5 of them are newborns. All 6 patients presented with fever, it was the main symptom for all of them. Only one of them needed oxygen; the others were hospitalized for surveillance but did not need specific care. In our series, coronavirus disease 2019 infection is mostly mild in neonates.
MeSH term(s)	Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/pathology ; Coronavirus Infections/physiopathology ; Female ; Fever/etiology ; France/epidemiology ; Hospitalization ; Humans ; Infant ; Infant, Newborn ; Male ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/physiopathology ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-05-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	392481-6
ISSN	1532-0987 ; 0891-3668
ISSN (online)	1532-0987
ISSN	0891-3668
DOI	10.1097/INF.0000000000002743
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