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  1. Book: Setting the stage for major depressive disorder recovery: strategies for the busy primary care provider

    Jackson, W. Clay / Thase, Michael E.

    W. Clay Jackson, MD, Michael E. Thase, MD

    (The journal of family practice ; vol 70, no 1, suppl. (iii) (January/February 2021))

    2021  

    Series title The journal of family practice ; vol 70, no 1, suppl. (iii) (January/February 2021)
    Collection
    Language English
    Size S19 Seiten, Diagramme
    Publisher Frontline Medical Communications Inc
    Publishing place Parsippany, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT020934464
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Ongoing phase 2/3 trials of psychotropic drugs: is help finally on the way?

    Thase, Michael E

    World psychiatry : official journal of the World Psychiatric Association (WPA)

    2023  Volume 22, Issue 1, Page(s) 80–82

    Language English
    Publishing date 2023-01-14
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2236130-3
    ISSN 2051-5545 ; 1723-8617
    ISSN (online) 2051-5545
    ISSN 1723-8617
    DOI 10.1002/wps.21064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Recent developments pertaining to treatment-resistant depression: a 40-year perspective.

    Thase, Michael E

    World psychiatry : official journal of the World Psychiatric Association (WPA)

    2023  Volume 22, Issue 3, Page(s) 413–414

    Language English
    Publishing date 2023-09-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2236130-3
    ISSN 2051-5545 ; 1723-8617
    ISSN (online) 2051-5545
    ISSN 1723-8617
    DOI 10.1002/wps.21134
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A New Option for Depressed Patients Who Do Not Respond to Antidepressant Medications.

    Thase, Michael E

    The American journal of psychiatry

    2023  Volume 180, Issue 3, Page(s) 188–189

    MeSH term(s) Humans ; Antidepressive Agents/therapeutic use ; Depression/drug therapy
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.20230039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Have Effective Antidepressants Finally Arrived? Developments in Major Depressive Disorder Therapy.

    Thase, Michael E

    The Journal of clinical psychiatry

    2023  Volume 84, Issue 4

    Abstract: Among the greatest unmet needs in major depressive disorder (MDD) is a lack of effective pharmacotherapies for patients who do not respond to first- and second-line antidepressant medications. After decades of muted progress, optimism regarding the ... ...

    Abstract Among the greatest unmet needs in major depressive disorder (MDD) is a lack of effective pharmacotherapies for patients who do not respond to first- and second-line antidepressant medications. After decades of muted progress, optimism regarding the future of MDD therapy rose after scientists serendipitously uncovered the antidepressant effects of ketamine. The discovery of ketamine's antidepressant effects inspired the search for related newer medications, such as
    MeSH term(s) Humans ; Depressive Disorder, Major/drug therapy ; Ketamine/therapeutic use ; Antidepressive Agents/adverse effects ; Hallucinogens/therapeutic use ; Depressive Disorder, Treatment-Resistant/drug therapy
    Chemical Substances Ketamine (690G0D6V8H) ; Antidepressive Agents ; Hallucinogens
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.mulmdd3048sho
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Commentary on the Hamilton Rating Scale for Depression: 60+ Years Old and Still Relevant to the Assessment of Antidepressant Treatment Outcomes.

    Thase, Michael E

    Psychopharmacology bulletin

    2022  Volume 52, Issue 2, Page(s) 154–156

    MeSH term(s) Antidepressive Agents/therapeutic use ; Depression/drug therapy ; Humans ; Middle Aged ; Psychiatric Status Rating Scales ; Treatment Outcome
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2022-06-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 4113-0
    ISSN 2472-2448 ; 0048-5764 ; 0376-0162
    ISSN (online) 2472-2448
    ISSN 0048-5764 ; 0376-0162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Strategies for Optimizing the Treatment of Major Depressive Disorder.

    Thase, Michael E

    The Journal of family practice

    2021  Volume 70, Issue 1 suppl [iii], Page(s) S11–S19

    MeSH term(s) Depressive Disorder, Major/therapy ; Humans ; Outcome Assessment, Health Care ; Patient Care Team/organization & administration ; Patient Participation/statistics & numerical data ; Patient Satisfaction ; Patient-Centered Care/organization & administration ; Primary Health Care/methods ; Primary Health Care/organization & administration
    Language English
    Publishing date 2021-03-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 197883-4
    ISSN 1533-7294 ; 0094-3509
    ISSN (online) 1533-7294
    ISSN 0094-3509
    DOI 10.12788/jfp.0140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Charting Sea Changes in Outpatient Pharmacotherapy of Bipolar Disorder.

    Thase, Michael E

    The American journal of psychiatry

    2020  Volume 177, Issue 8, Page(s) 651–653

    MeSH term(s) Antipsychotic Agents ; Bipolar Disorder ; Depression ; Depressive Disorder, Treatment-Resistant ; Humans ; Outpatients
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2020-09-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2020.20060849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Phase 2 Open Label Study of Efficacy, Safety, and Tolerability of SLS-002 (Intranasal Racemic Ketamine) in Adults with MDD at Imminent Risk of Suicide.

    Whitaker, Timothy / Farrand, Kimberly F / Thase, Michael E

    Psychopharmacology bulletin

    2024  Volume 54, Issue 1, Page(s) 8–17

    Abstract: Background: Despite the prevalence of Major Depressive Disorder (MDD) and the propensity of affected individuals to eventually die by suicide, there is no therapeutic approved specifically for suicidal ideation and behavior (SI/B) in MDD. The NMDA ... ...

    Abstract Background: Despite the prevalence of Major Depressive Disorder (MDD) and the propensity of affected individuals to eventually die by suicide, there is no therapeutic approved specifically for suicidal ideation and behavior (SI/B) in MDD. The NMDA receptor antagonist ketamine has been investigated for the treatment of depression and shown to have a rapid effect on symptoms. Spravato
    Methods: In part one of a two-part clinical trial, the safety, tolerability, and potential effectiveness of SLS-002 were evaluated in an open label study of 17 patients with MDD hospitalized with acute SI/B.
    Results: Treatment with SLS-002 was associated with a significant reduction in depression and suicidality indicators on four clinical scales: the Montgomery-Åsberg Depression Rating Scale, the Sheehan-Suicidality Tracking Scale, and the Clinical and Patient Global Impression Scales for SI/B. SLS-002 was well tolerated with an acceptable safety profile.
    Conclusions: The results of this open label study support the continued development of SLS-002. The randomized double-blind placebo-controlled part two of this trial was recently completed.
    MeSH term(s) Adult ; Humans ; Analgesics ; Depressive Disorder, Major/drug therapy ; Ketamine/adverse effects ; Suicidal Ideation ; Suicide
    Chemical Substances Analgesics ; Esketamine (50LFG02TXD) ; Ketamine (690G0D6V8H)
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Clinical Trial, Phase II ; Journal Article
    ZDB-ID 4113-0
    ISSN 2472-2448 ; 0048-5764 ; 0376-0162
    ISSN (online) 2472-2448
    ISSN 0048-5764 ; 0376-0162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Augmentation strategies in the treatment of major depressive disorder

    Thase, Michael E.

    expert roundtable supplement

    (Primary psychiatry ; 14,12, Suppl. 7)

    2007  

    Author's details authors Michael E. Thase
    Series title Primary psychiatry ; 14,12, Suppl. 7
    Collection
    Language English
    Size 19 S. : Ill., graph. Darst.
    Publisher MBL Communications
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT015471435
    Database Catalogue ZB MED Medicine, Health

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