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  1. Article ; Online: Women's Self-Management of Dyspareunia Associated With Endometriosis: A Qualitative Study.

    Howard, A Fuchsia / Noga, Heather / Kelly, Mary T / Gholamian, Bita / Lett, Sarah / Sutherland, Jessica / Yong, Paul J

    The journal of pain

    2024  

    Abstract: ... with intimate partner(s). Women in this study developed self-management strategies over time through engagement ...

    Abstract Given the limitations of medical treatment for endometriosis, self-management is a critical component of symptom management, and providing patients with information and education is a necessary complement to medical interventions. Though 50 to 70% of people with endometriosis experience dyspareunia (painful sex), there is limited knowledge of self-management specific to painful sex. A comprehensive understanding of the self-management strategies used is foundational to developing supportive care interventions that help ease pain and related psychosocial sequelae. The objective was to describe people's experiences of navigating endometriosis-associated painful sex and developing self-management strategies. We analyzed interview data from 20 women using constant comparative and thematic analysis techniques, guided by qualitative interpretive description methodology. Participants (age range 18-44 years) all identified as women and were predominately Caucasian (90%) and heterosexual (80%). Throughout their lives, the women appeared to gradually develop self-management strategies while navigating painful sexual experiences. This complex journey encompassed four phases: 1) viewing painful sex as normal, 2) experiencing evolving thoughts and emotions, 3) coming to understand painful sex and seeking help, and 4) learning strategies to navigate painful sex, these include preparing mentally and physically for sex and communicating with intimate partner(s). Women in this study developed self-management strategies over time through engagement with others who understood their challenges. Future research is warranted regarding initiatives to counter the normalization of painful sex, develop and disseminate patient-facing information, provide education specific to dyspareunia, improve access to multidisciplinary care, facilitate social connections and support, and enhance communication with intimate partners. PERSPECTIVE: In this paper, we report on the experiences of women with endometriosis-associated painful sex and their self-management strategies. Clinicians may be interested in a qualitative exploration of endometriosis-associated painful sex as they seek to further understand their patient's experiences and what strategies can be implemented to alleviate dyspareunia. DATA AVAILABILITY: The data sets generated during and/or analyzed during the current study are not publicly available as participants did not consent to making their data publicly available but are available from the corresponding author on reasonable request.
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018789-0
    ISSN 1528-8447 ; 1526-5900
    ISSN (online) 1528-8447
    ISSN 1526-5900
    DOI 10.1016/j.jpain.2024.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Depression and cardiac risk.

    Blumenthal, James A / Lett, Heather S

    Journal of cardiopulmonary rehabilitation

    2005  Volume 25, Issue 2, Page(s) 78–79

    MeSH term(s) Antidepressive Agents/therapeutic use ; Coronary Disease/psychology ; Coronary Disease/rehabilitation ; Depressive Disorder/epidemiology ; Depressive Disorder/therapy ; Exercise ; Female ; Humans ; Interview, Psychological ; Male ; Prevalence ; Prognosis ; Psychotherapy ; Risk Factors ; Sex Distribution
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2005-03-29
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 632679-1
    ISSN 0883-9212 ; 0275-1429
    ISSN 0883-9212 ; 0275-1429
    DOI 10.1097/00008483-200503000-00005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nonpharmacologic treatments for depression in patients with coronary heart disease.

    Lett, Heather S / Davidson, Jonathan / Blumenthal, James A

    Psychosomatic medicine

    2005  Volume 67 Suppl 1, Page(s) S58–62

    Abstract: ... S-Adenosylmethionine (SAMe), acupuncture, and chromium picolinate (CP).: Method: Medline searches and reviews ...

    Abstract Objectives: We review nonpharmacologic treatments for depression in patients with coronary heart disease (CHD), including psychological therapies such as cognitive behavior therapy (CBT) and interpersonal therapy (IPT), aerobic exercise, St. John's wort (SJW), essential fatty acids (EFAs), S-Adenosylmethionine (SAMe), acupuncture, and chromium picolinate (CP).
    Method: Medline searches and reviews of bibliographies were used to identify relevant articles. Each treatment was reviewed with particular attention paid to empirical support, as well as to potential mechanisms of action that might affect not only depression but also CHD endpoints.
    Results: Nearly all randomized controlled trials (RCTs) of depression treatments have been conducted with non-CHD patients. These studies have provided the most support for psychological treatments, particularly CBT and IPT. Aerobic exercise, SJW, and SAMe also have considerable empirical support in otherwise healthy persons, but SJW may have undesirable side effects for CHD patients. Data for EFAs, CP, and acupuncture are limited; however, the use of aerobic exercise shows considerable promise for cardiac patients.
    Conclusions: There are few RCTs of patients with clinical depression and CHD, and those that exist have significant methodological limitations. Nonetheless, there is preliminary evidence that nonpharmacologic treatments are effective for cardiac patients with depression. In terms of reducing depression, the most evidence exists for psychological treatments, particularly CBT and IPT. However, there is little evidence that such treatment would also improve CHD risk factors. Aerobic exercise offers more promise to improve both mental and physical health due to its effect on cardiovascular risk factors and outcomes and thus warrants particular attention in future trials.
    MeSH term(s) Acupuncture Therapy ; Antidepressive Agents/therapeutic use ; Coronary Disease/etiology ; Depression/complications ; Depression/therapy ; Exercise ; Fatty Acids, Essential/economics ; Fatty Acids, Essential/therapeutic use ; Humans ; Hypericum ; Phytotherapy ; Picolinic Acids/therapeutic use ; Psychotherapy ; S-Adenosylmethionine/analogs & derivatives ; S-Adenosylmethionine/therapeutic use
    Chemical Substances Antidepressive Agents ; Fatty Acids, Essential ; Picolinic Acids ; adenosyl-methionine 1,4-butanedisulfonate ; S-Adenosylmethionine (7LP2MPO46S) ; picolinic acid (QZV2W997JQ)
    Language English
    Publishing date 2005-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 3469-1
    ISSN 1534-7796 ; 0033-3174
    ISSN (online) 1534-7796
    ISSN 0033-3174
    DOI 10.1097/01.psy.0000163453.24417.97
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Depression and cardiac function in patients with stable coronary heart disease: findings from the Heart and Soul Study.

    Lett, Heather / Ali, Sadia / Whooley, Mary

    Psychosomatic medicine

    2008  Volume 70, Issue 4, Page(s) 444–449

    Abstract: Objective: To determine whether depression is associated with worse cardiac disease severity in patients with stable coronary heart disease (CHD). There is considerable evidence that depression is a risk factor for adverse cardiovascular events in ... ...

    Abstract Objective: To determine whether depression is associated with worse cardiac disease severity in patients with stable coronary heart disease (CHD). There is considerable evidence that depression is a risk factor for adverse cardiovascular events in patients with CHD. However, a frequent criticism of this literature is that the association between depression and adverse cardiovascular outcomes may be confounded by worse baseline cardiac disease severity in depressed patients.
    Method: In a sample of 1020 outpatients with stable CHD, we examined the association between major depression (assessed using the Computerized National Institute of Mental Health Diagnostic Interview Schedule) with measures of cardiac disease severity, including systolic dysfunction, diastolic dysfunction, exercise-induced ischemia, and cardiac wall motion abnormalities. Cross-sectional univariate and multivariate models controlling for demographic and clinical variables were computed.
    Results: Of the 1020 participants, 224 (22%) had current (past month) major depression. After adjustment for age, major depression was not associated with systolic dysfunction, diastolic dysfunction, inducible ischemia, or cardiac wall motion abnormalities. Similarly, multivariate models revealed no significant relationship between major depression and cardiac disease severity.
    Conclusions: Overall, we found little evidence that depression is associated with worse cardiac disease severity. This suggests that greater baseline cardiac disease severity is unlikely to be responsible for the increased risk of CHD events in depressed patients.
    MeSH term(s) Aged ; Analysis of Variance ; Comorbidity ; Coronary Disease/epidemiology ; Coronary Disease/physiopathology ; Coronary Disease/psychology ; Cross-Sectional Studies ; Depressive Disorder, Major/epidemiology ; Depressive Disorder, Major/physiopathology ; Depressive Disorder, Major/psychology ; Diastole/physiology ; Echocardiography, Stress ; Female ; Heart Function Tests ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Myocardial Contraction/physiology ; Myocardial Infarction/epidemiology ; Myocardial Infarction/physiopathology ; Myocardial Infarction/psychology ; Myocardial Ischemia/epidemiology ; Myocardial Ischemia/physiopathology ; Myocardial Ischemia/psychology ; Risk Factors ; Statistics as Topic ; Systole/physiology ; Ventricular Dysfunction, Left/epidemiology ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Dysfunction, Left/psychology
    Language English
    Publishing date 2008-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3469-1
    ISSN 1534-7796 ; 0033-3174
    ISSN (online) 1534-7796
    ISSN 0033-3174
    DOI 10.1097/PSY.0b013e31816c3c5c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Exercise and the treatment of clinical depression in adults: recent findings and future directions.

    Brosse, Alisha L / Sheets, Erin S / Lett, Heather S / Blumenthal, James A

    Sports medicine (Auckland, N.Z.)

    2002  Volume 32, Issue 12, Page(s) 741–760

    Abstract: This article critically reviews the evidence that exercise is effective in treating depression in adults. Depression is recognised as a mood state, clinical syndrome and psychiatric condition, and traditional methods for assessing depression (e.g. ... ...

    Abstract This article critically reviews the evidence that exercise is effective in treating depression in adults. Depression is recognised as a mood state, clinical syndrome and psychiatric condition, and traditional methods for assessing depression (e.g. standard interviews, questionnaires) are described. In order to place exercise therapy into context, more established methods for treating clinical depression are discussed. Observational (e.g. cross-sectional and correlational) and interventional studies of exercise are reviewed in healthy adults, those with comorbid medical conditions, and patients with major depression. Potential mechanisms by which exercise may reduce depression are described, and directions for future research in the area are suggested. The available evidence provides considerable support for the value of exercise in reducing depressive symptoms in both healthy and clinical populations. However, many studies have significant methodological limitations. Thus, more data from carefully conducted clinical trials are needed before exercise can be recommended as an alternative to more traditional, empirically validated pharmacological and behavioural therapies.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chronic Disease ; Depression/diagnosis ; Depression/epidemiology ; Depression/therapy ; Exercise ; Female ; Humans ; Male ; Middle Aged
    Language English
    Publishing date 2002-06-18
    Publishing country New Zealand
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.2165/00007256-200232120-00001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A prospective multi-faceted interventional study of blood bank technologist screening of red blood cell transfusion orders: The START study.

    Kron, Amie T / Collins, Allison / Cserti-Gazdewich, Christine / Pendergrast, Jacob / Webert, Kathryn / Lieberman, Lani / Zeller, Michelle P / Harding, Sheila R / Nahirniak, Susan / Prokopchuk-Gauk, Oksana / Lin, Yulia / Mendez, Brent / Armali, Chantal / Lee, Christina / Watson, Danielle / Arnott, Dena / Xun, Fengju / Blain, Heather / Panchuk, Heather /
    Hughes, Hertha / Chorneyko, Kathy / Angers, Michael / Pilutti, Nicole / Lett, Ryan / Dowsley, Shauna / Ruijs, Theodora / Cupido, Tracy / Kichinko, Tracy / Thompson, Troy / Afshar-Ghotli, Zohreh / Callum, Jeannie

    Transfusion

    2021  Volume 61, Issue 2, Page(s) 410–422

    Abstract: Background: Transfusion of red blood cells (RBC) is a common procedure, which when prescribed inappropriately can result in adverse patient outcomes. This study sought to determine the impact of a multi-faceted intervention on unnecessary RBC ... ...

    Abstract Background: Transfusion of red blood cells (RBC) is a common procedure, which when prescribed inappropriately can result in adverse patient outcomes. This study sought to determine the impact of a multi-faceted intervention on unnecessary RBC transfusions at hospitals with a baseline appropriateness below 90%.
    Study design and methods: A prospective medical chart audit of RBC transfusions was conducted across 15 hospitals. For each site, 10 RBCs per month transfused to inpatients were audited for a 5-month pre- and 10-month post-intervention period, with each transfusion adjudicated for appropriateness based on pre-set criteria. Hospitals with appropriateness rates below 90% underwent a 3-month intervention which included: adoption of standardized RBC guidelines, staff education, and prospective transfusion order screening by blood bank technologists. Proportions of RBC transfusions adjudicated as appropriate and the total number of RBC units transfused per month in the pre- and post-intervention period were examined.
    Results: Over the 15-month audit period, at the 13 hospital sites with a baseline appropriateness below 90%, 1950 patients were audited of which 81.2% were adjudicated as appropriate. Proportions of appropriateness and single-unit orders increased from 73.5% to 85% and 46.2% to 68.2%, respectively from pre- to post-intervention (P < .0001). Pre- and post-transfusion hemoglobin levels and the total number of RBCs transfused decreased from baseline (P < .05). The median pre-transfusion hemoglobin decreased from a baseline of 72.0 g/L to 69.0 g/L in the post-intervention period (P < .0001). RBC transfusions per acute inpatient days decreased significantly in intervention hospitals, but not in control hospitals (P < .001). The intervention had no impact on patient length of stay, need for intensive care support, or in-hospital mortality.
    Conclusion: This multifaceted intervention demonstrated a marked improvement in RBC transfusion appropriateness and reduced overall RBC utilization without impacts on patient safety.
    MeSH term(s) Academic Medical Centers/organization & administration ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Blood Banks ; Erythrocyte Transfusion ; Hemoglobins/analysis ; Hospital Departments/statistics & numerical data ; Hospitals, Community/organization & administration ; Humans ; Inappropriate Prescribing/statistics & numerical data ; Male ; Medical Audit ; Medical Laboratory Personnel ; Middle Aged ; Patient Safety ; Prescriptions ; Procedures and Techniques Utilization/statistics & numerical data ; Prospective Studies ; Quality Improvement ; Unnecessary Procedures/statistics & numerical data ; Young Adult
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2021-01-10
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.16243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Social support and coronary heart disease: epidemiologic evidence and implications for treatment.

    Lett, Heather S / Blumenthal, James A / Babyak, Michael A / Strauman, Timothy J / Robins, Clive / Sherwood, Andrew

    Psychosomatic medicine

    2005  Volume 67, Issue 6, Page(s) 869–878

    Abstract: Objective: The present paper reviews theories of social support and evidence for the role of social support in the development and progression of coronary heart disease (CHD).: Methods: Articles for the primary review of social support as a risk ... ...

    Abstract Objective: The present paper reviews theories of social support and evidence for the role of social support in the development and progression of coronary heart disease (CHD).
    Methods: Articles for the primary review of social support as a risk factor were identified with MEDLINE (1966-2004) and PsychINFO (1872-2004). Reviews of bibliographies also were used to identify relevant articles.
    Results: In general, evidence suggests that low social support confers a risk of 1.5 to 2.0 in both healthy populations and in patients with established CHD. However, there is substantial variability in the manner in which social support is conceptualized and measured. In addition, few studies have simultaneously compared differing types of support.
    Conclusions: Although low levels of support are associated with increased risk for CHD events, it is not clear what types of support are most associated with clinical outcomes in healthy persons and CHD patients. The development of a consensus in the conceptualization and measurement of social support is needed to examine which types of support are most likely to be associated with adverse CHD outcomes. There also is little evidence that improving low social support reduces CHD events.
    MeSH term(s) Comorbidity ; Coronary Disease/diagnosis ; Coronary Disease/epidemiology ; Coronary Disease/physiopathology ; Depressive Disorder/epidemiology ; Depressive Disorder/physiopathology ; Female ; Health Behavior ; Humans ; Male ; Outcome Assessment (Health Care) ; Prognosis ; Prospective Studies ; Psychological Theory ; Risk Factors ; Social Class ; Social Support ; Terminology as Topic
    Language English
    Publishing date 2005-11
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 3469-1
    ISSN 1534-7796 ; 0033-3174
    ISSN (online) 1534-7796
    ISSN 0033-3174
    DOI 10.1097/01.psy.0000188393.73571.0a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Dimensions of social support and depression in patients at increased psychosocial risk recovering from myocardial infarction.

    Lett, Heather S / Blumenthal, James A / Babyak, Michael A / Catellier, Diane J / Carney, Robert M / Berkman, Lisa F / Burg, Matthew M / Mitchell, Pamela / Jaffe, Allan S / Schneiderman, Neil

    International journal of behavioral medicine

    2009  Volume 16, Issue 3, Page(s) 248–258

    Abstract: Background: There is considerable evidence that depression and low social support are associated with increased morbidity and mortality for patients with coronary heart disease (CHD). However, there is a lack of consensus regarding the measurement of ... ...

    Abstract Background: There is considerable evidence that depression and low social support are associated with increased morbidity and mortality for patients with coronary heart disease (CHD). However, there is a lack of consensus regarding the measurement of social support and its relation to depression.
    Purpose: The primary purpose of the present study was to identify key dimensions of existing social support and depression measures for patients with CHD using factor analysis.
    Method: Seven hundred-five patients with a recent acute myocardial infarction and either depression, low social support, or both, completed measures of several types of social support and depression. Exploratory and confirmatory factor analysis were used to examine the underlying dimensions of the existing social support and depression measures, and to compare theoretically plausible models specifying the relation between the social support and depression factors.
    Results: Confirmatory factor analysis indicated that an approach in which smaller facets of depression are measured (somatic, cognitive/affective, anxious) and social support (perceived emotional support from intimate relationships; perceived tangible support from peripheral contacts; and the number of children, relatives, and friends in a patient's support network), may be the most optimal way to measure social support and depression in this population RMSEA = 0.05; CFI = 0.81; TLI = 0.88).
    Conclusion: Efforts to identify patients at increased psychosocial risk may be improved by screening for these subcomponents of social support and depression.
    MeSH term(s) Adult ; Aged ; Anxiety Disorders/diagnosis ; Anxiety Disorders/psychology ; Convalescence ; Depressive Disorder/diagnosis ; Depressive Disorder/psychology ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/psychology ; Dysthymic Disorder/diagnosis ; Dysthymic Disorder/psychology ; Factor Analysis, Statistical ; Female ; Humans ; Male ; Mass Screening/statistics & numerical data ; Middle Aged ; Models, Psychological ; Multicenter Studies as Topic ; Myocardial Infarction/psychology ; Personality Inventory/statistics & numerical data ; Psychometrics ; Randomized Controlled Trials as Topic ; Risk Factors ; Social Support
    Language English
    Publishing date 2009-03-17
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1187972-5
    ISSN 1532-7558 ; 1070-5503
    ISSN (online) 1532-7558
    ISSN 1070-5503
    DOI 10.1007/s12529-009-9040-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment.

    Lett, Heather S / Blumenthal, James A / Babyak, Michael A / Sherwood, Andrew / Strauman, Timothy / Robins, Clive / Newman, Mark F

    Psychosomatic medicine

    2004  Volume 66, Issue 3, Page(s) 305–315

    Abstract: Objective: The present paper reviews the evidence that depression is a risk factor for the development and progression of coronary artery disease (CAD).: Methods: MEDLINE searches and reviews of bibliographies were used to identify relevant articles. ...

    Abstract Objective: The present paper reviews the evidence that depression is a risk factor for the development and progression of coronary artery disease (CAD).
    Methods: MEDLINE searches and reviews of bibliographies were used to identify relevant articles. Articles were clustered by theme: depression as a risk factor, biobehavioral mechanisms, and treatment outcome studies.
    Results: Depression confers a relative risk between 1.5 and 2.0 for the onset of CAD in healthy individuals, whereas depression in patients with existing CAD confers a relative risk between 1.5 and 2.5 for cardiac morbidity and mortality. A number of plausible biobehavioral mechanisms linking depression and CAD have been identified, including treatment adherence, lifestyle factors, traditional risk factors, alterations in autonomic nervous system (ANS) and hypothalamic pituitary adrenal (HPA) axis functioning, platelet activation, and inflammation.
    Conclusion: There is substantial evidence for a relationship between depression and adverse clinical outcomes. However, despite the availability of effective therapies for depression, there is a paucity of data to support the efficacy of these interventions to improve clinical outcomes for depressed CAD patients. Randomized clinical trials are needed to further evaluate the value of treating depression in CAD patients to improve survival and reduce morbidity.
    MeSH term(s) Alcohol Drinking/epidemiology ; Antidepressive Agents/therapeutic use ; Case-Control Studies ; Cause of Death ; Comorbidity ; Coronary Disease/epidemiology ; Coronary Disease/etiology ; Coronary Disease/mortality ; Depressive Disorder/epidemiology ; Depressive Disorder/mortality ; Depressive Disorder/therapy ; Dexamethasone ; Female ; Humans ; Hydrocortisone/blood ; Longitudinal Studies ; Male ; Metabolic Syndrome/epidemiology ; Prognosis ; Psychotherapy ; Psychotherapy, Group ; Risk Factors ; Serotonin Uptake Inhibitors/therapeutic use ; Smoking/epidemiology
    Chemical Substances Antidepressive Agents ; Serotonin Uptake Inhibitors ; Dexamethasone (7S5I7G3JQL) ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2004-05-01
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 3469-1
    ISSN 1534-7796 ; 0033-3174
    ISSN (online) 1534-7796
    ISSN 0033-3174
    DOI 10.1097/01.psy.0000126207.43307.c0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Social support and prognosis in patients at increased psychosocial risk recovering from myocardial infarction.

    Lett, Heather S / Blumenthal, James A / Babyak, Michael A / Catellier, Diane J / Carney, Robert M / Berkman, Lisa F / Burg, Matthew M / Mitchell, Pamela / Jaffe, Allan S / Schneiderman, Neil

    Health psychology : official journal of the Division of Health Psychology, American Psychological Association

    2007  Volume 26, Issue 4, Page(s) 418–427

    Abstract: Objective: To compare the impact of network support and different types of perceived functional support on all-cause mortality or nonfatal reinfarction for patients with a recent acute myocardial infarction (AMI).: Design: Participants were recruited ...

    Abstract Objective: To compare the impact of network support and different types of perceived functional support on all-cause mortality or nonfatal reinfarction for patients with a recent acute myocardial infarction (AMI).
    Design: Participants were recruited from the Enhancing Recovery in Coronary Heart Disease (ENRICHD) trial; 2,481 AMI patients with depression or low social support were randomized to a cognitive-behavioral intervention or to a usual care control group. Data collection for certain measures of social support was limited: 2,466 participants completed the ENRICHD Social Support Inventory; 2,457 completed the Perceived Social Support Scale; 1,296 completed the Social Network Questionnaire; and 707 completed the Interpersonal Support and Evaluation List, Tangible Support subscale. Patients also completed the Beck Depression Inventory and were followed for up to 4.5 years.
    Main outcome measure: Time to death or nonfatal reinfarction.
    Results: Over the follow-up period, 599 patients (24%) died or had a nonfatal AMI. Survival models controlling age, sex, race, socioeconomic status, smoking, antidepressant use, and a composite measure of increased risk revealed that higher levels of perceived social support were associated with improved outcome for patients without elevated depression but not for patients with high levels of depression. Neither perceived tangible support nor network support were associated with more frequent adverse events.
    Conclusion: AMI patients should be assessed for multiple dimensions of perceived functional support and depression to identify those at increased psychosocial risk who may benefit from treatment.
    MeSH term(s) Cause of Death ; Cognitive Therapy ; Comorbidity ; Depressive Disorder/diagnosis ; Depressive Disorder/epidemiology ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Myocardial Infarction/diagnosis ; Myocardial Infarction/mortality ; Myocardial Infarction/therapy ; Outcome Assessment (Health Care) ; Personality Inventory/statistics & numerical data ; Prognosis ; Proportional Hazards Models ; Risk Factors ; Social Support ; Surveys and Questionnaires
    Language English
    Publishing date 2007-07
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
    ZDB-ID 226369-5
    ISSN 1930-7810 ; 0278-6133
    ISSN (online) 1930-7810
    ISSN 0278-6133
    DOI 10.1037/0278-6133.26.4.418
    Database MEDical Literature Analysis and Retrieval System OnLINE

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