LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 625

Search options

  1. Article ; Online: Bioluminescence Color-Tuning Firefly Luciferases: Engineering and Prospects for Real-Time Intracellular pH Imaging and Heavy Metal Biosensing.

    Viviani, Vadim R / Pelentir, Gabriel F / Bevilaqua, Vanessa R

    Biosensors

    2022  Volume 12, Issue 6

    Abstract: Firefly luciferases catalyze the efficient production of yellow-green light under normal physiological conditions, having been extensively used for bioanalytical purposes for over 5 decades. Under acidic conditions, high temperatures and the presence of ... ...

    Abstract Firefly luciferases catalyze the efficient production of yellow-green light under normal physiological conditions, having been extensively used for bioanalytical purposes for over 5 decades. Under acidic conditions, high temperatures and the presence of heavy metals, they produce red light, a property that is called pH-sensitivity or pH-dependency. Despite the demand for physiological intracellular biosensors for pH and heavy metals, firefly luciferase pH and metal sensitivities were considered drawbacks in analytical assays. We first demonstrated that firefly luciferases and their pH and metal sensitivities can be harnessed to estimate intracellular pH variations and toxic metal concentrations through ratiometric analysis. Using
    MeSH term(s) Animals ; Fireflies/genetics ; Hydrogen-Ion Concentration ; Luciferases/chemistry ; Luciferases/genetics ; Luciferases, Firefly/chemistry ; Luciferases, Firefly/genetics ; Luminescent Measurements/methods ; Mammals ; Mercury ; Metals, Heavy/chemistry
    Chemical Substances Metals, Heavy ; Luciferases (EC 1.13.12.-) ; Luciferases, Firefly (EC 1.13.12.7) ; Mercury (FXS1BY2PGL)
    Language English
    Publishing date 2022-06-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios12060400
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Successful use of adalimumab in treating granuloma faciale resistant to traditional therapies.

    Mussi, Martina / Zengarini, Corrado / Viviani, Filippo / Sacchelli, Lidia / Pileri, Alessandro / Bardazzi, Federico

    The Australasian journal of dermatology

    2024  

    Language English
    Publishing date 2024-04-14
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.14260
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Sandoven-f-Behandlung ambulanter Patienten mit venösen Erkrankungen

    Viviani, E

    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis

    1975  Volume 64, Issue 41, Page(s) 1320–1323

    Title translation Treatment by sandoven-f in patients with venous affections (author's transl).
    MeSH term(s) Adult ; Aged ; Coumarins/therapeutic use ; Dihydroergotoxine/therapeutic use ; Drug Combinations ; Drug Evaluation ; Ergoloid Mesylates/therapeutic use ; Esculin/therapeutic use ; Female ; Flavonoids/therapeutic use ; Humans ; Male ; Middle Aged ; Rutin/therapeutic use ; Venous Insufficiency/drug therapy
    Chemical Substances Coumarins ; Drug Combinations ; Flavonoids ; Dihydroergotoxine (11032-41-0) ; Esculin (1Y1L18LQAF) ; Rutin (5G06TVY3R7) ; Ergoloid Mesylates (8067-24-1)
    Language German
    Publishing date 1975-10-14
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 209026-0
    ISSN 1661-8165 ; 1013-2058 ; 1661-8157 ; 0369-8394
    ISSN (online) 1661-8165
    ISSN 1013-2058 ; 1661-8157 ; 0369-8394
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: PHA and EPS production from industrial wastewater by conventional activated sludge, membrane bioreactor and aerobic granular sludge technologies: A comprehensive comparison.

    Traina, Francesco / Capodici, Marco / Torregrossa, Michele / Viviani, Gaspare / Corsino, Santo Fabio

    Chemosphere

    2024  Volume 355, Page(s) 141768

    Abstract: The present study has focused on the mainstream integration of polyhydroxyalkanoate (PHA) production with industrial wastewater treatment by exploiting three different technologies all operating in sequencing batch reactors (SBR): conventional activated ... ...

    Abstract The present study has focused on the mainstream integration of polyhydroxyalkanoate (PHA) production with industrial wastewater treatment by exploiting three different technologies all operating in sequencing batch reactors (SBR): conventional activated sludge (AS-SBR), membrane bioreactor (AS-MBR) and aerobic granular sludge (AGS). A full aerobic feast/famine strategy was adopted to obtain enrichment of biomass with PHA-storing bacteria. All the systems were operated at different organic loading (OLR) rate equal to 1-2-3 kgCOD/m
    MeSH term(s) Wastewater ; Sewage/chemistry ; Polyhydroxyalkanoates ; Bioreactors/microbiology ; Bacteria/metabolism ; Carbon/metabolism ; Waste Disposal, Fluid/methods
    Chemical Substances Wastewater ; Sewage ; Polyhydroxyalkanoates ; Carbon (7440-44-0)
    Language English
    Publishing date 2024-03-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141768
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: On the relationship between emotions and cognitive control: Evidence from an observational study on emotional priming Stroop task.

    Visalli, Antonino / Ambrosini, Ettore / Viviani, Giada / Sambataro, Fabio / Tenconi, Elena / Vallesi, Antonino

    PloS one

    2023  Volume 18, Issue 11, Page(s) e0294957

    Abstract: Evidence is discordant regarding how emotional processing and cognitive control interact to shape behavior. This observational study sought to examine this interaction by looking at the distinction between proactive and reactive modes of control and how ... ...

    Abstract Evidence is discordant regarding how emotional processing and cognitive control interact to shape behavior. This observational study sought to examine this interaction by looking at the distinction between proactive and reactive modes of control and how they relate to emotional processing. Seventy-four healthy participants performed an emotional priming Stroop task. On each trial, target stimuli of a spatial Stroop task were preceded by sad or neutral facial expressions, providing two emotional conditions. To manipulate the requirement of both proactive and reactive control, the proportion of congruent trials (PC) was varied at the list-wide (LWPC) and item-specific (ISPC) levels, respectively. We found that sad priming led to behavioral costs only in trials with low proactive and reactive cognitive control demands. Our findings suggest that emotional processing affects cognitive processes other than cognitive control in the Stroop task. Moreover, both proactive and reactive control modes seem effective in overcoming emotional interference of priming stimuli.
    MeSH term(s) Humans ; Stroop Test ; Emotions ; Mood Disorders ; Facial Expression ; Cognition ; Reaction Time
    Language English
    Publishing date 2023-11-27
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0294957
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Exploring avibactam and relebactam inhibition of

    Alsenani, T A / Viviani, S L / Papp-Wallace, K M / Bonomo, R A / van den Akker, F

    Antimicrobial agents and chemotherapy

    2023  Volume 67, Issue 10, Page(s) e0035023

    Abstract: Klebsiella ... ...

    Abstract Klebsiella pneumoniae
    MeSH term(s) Ceftazidime/pharmacology ; Anti-Bacterial Agents/pharmacology ; Klebsiella pneumoniae/genetics ; Water ; beta-Lactamases/genetics ; beta-Lactamases/chemistry ; Bacterial Proteins/genetics ; Azabicyclo Compounds/pharmacology ; Azabicyclo Compounds/chemistry ; beta-Lactamase Inhibitors/pharmacology ; Carbapenems ; Drug Combinations ; Imines ; Microbial Sensitivity Tests
    Chemical Substances Ceftazidime (9M416Z9QNR) ; carbapenemase (EC 3.5.2.6) ; Anti-Bacterial Agents ; relebactam (Y1MYA2UHFL) ; avibactam (7352665165) ; Water (059QF0KO0R) ; beta-Lactamases (EC 3.5.2.6) ; Bacterial Proteins ; Azabicyclo Compounds ; beta-Lactamase Inhibitors ; Carbapenems ; Drug Combinations ; Imines
    Language English
    Publishing date 2023-09-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.00350-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Combined recovery of polyhydroxyalkanoates and reclaimed water in the mainstream of a WWTP for agro-food industrial wastewater valorisation by membrane bioreactor technology.

    Traina, Francesco / Corsino, Santo Fabio / Capodici, Marco / Licitra, Enrico / Di Bella, Gaetano / Torregrossa, Michele / Viviani, Gaspare

    Journal of environmental management

    2023  Volume 351, Page(s) 119836

    Abstract: ... the same wastewater under different food to microorganisms' ratios (F/M) ranging between 0.125 and 0.650 ...

    Abstract The present study investigated the combined production of reclaimed water for reuse purposes and polyhydroxyalkanoates (PHA) from an agro-food industrial wastewater. A pilot plant implementing a two-stage process for PHA production was studied. It consisted of a mainstream sequencing batch membrane bioreactor (SBMBR) in which selection of PHA-accumulating organisms and wastewater treatment were carried out in, and a side-stream fed-batch reactor (FBR) where the excess sludge from the SBMBR was used for PHA accumulation. The performance of the SBMBR was compared with that of a conventional sequencing batch reactor (SBR) treating the same wastewater under different food to microorganisms' ratios (F/M) ranging between 0.125 and 0.650 kgCOD kgTSS
    MeSH term(s) Wastewater ; Polyhydroxyalkanoates ; Bioreactors/microbiology ; Sewage ; Bacteria
    Chemical Substances Wastewater ; Polyhydroxyalkanoates ; Sewage
    Language English
    Publishing date 2023-12-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2023.119836
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: The orange light emitting luciferase from the rare Euryopa clarindae adult railroadworm (Coleoptera:Phengodidae): structural/functional and evolutionary relationship with green and red emitting luciferases.

    Viviani, V R / Benites, G R / Souza, D R / Pelentir, G F / Reis, Raone M / Bechara, Etelvino J H / Tomazini, Atilio

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

    2023  Volume 23, Issue 2, Page(s) 257–269

    Abstract: Railroadworms luciferases emit the widest range of bioluminescence colors among beetles, ranging from green to red, being model enzymes to investigate the structure and bioluminescence colors relationships. Only three active railroadworms luciferases ... ...

    Abstract Railroadworms luciferases emit the widest range of bioluminescence colors among beetles, ranging from green to red, being model enzymes to investigate the structure and bioluminescence colors relationships. Only three active railroadworms luciferases from the larval stage have been cloned and investigated: the Phrixothrix hirtus head lanterns red-emitting luciferase (PhRE); the Phrixothrix vivianii lateral lanterns green emitting luciferases (PvGR) and the Phengodes sp. dorsal lanterns yellow-green emitting luciferase (Ph). No active luciferase emitting in the yellow-orange region, however, has been cloned yet. Here we report the cloning and characterization of the orange emitting luciferase from the adult males of a rare Brazilian Cerrado railroadworm, Euryopa clarindae, and the transcriptional identification of two isozymes from the Amazon forest Mastinomorphus sp. railroadworm. The luciferase of E. clarindae has 548 residues, emits orange bioluminescence (600 nm), and displays intermediate kinetic values [K
    MeSH term(s) Animals ; Coleoptera ; Phylogeny ; Luciferases/genetics ; Luciferases/chemistry ; Larva ; Brazil ; Luminescent Measurements ; Luciferases, Firefly
    Chemical Substances Luciferases (EC 1.13.12.-) ; Luciferases, Firefly (EC 1.13.12.7)
    Language English
    Publishing date 2023-12-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2072584-X
    ISSN 1474-9092 ; 1474-905X
    ISSN (online) 1474-9092
    ISSN 1474-905X
    DOI 10.1007/s43630-023-00515-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Dermatology residents and COVID-19: life behind the frontlines.

    Viviani, F / Ferrari, T / Mussi, M / Zengarini, C / Orioni, G

    Clinical and experimental dermatology

    2020  Volume 46, Issue 1, Page(s) 169–170

    MeSH term(s) COVID-19/epidemiology ; Dermatology/education ; Dermatology/organization & administration ; Humans ; Internship and Residency/organization & administration ; Italy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-26
    Publishing country England
    Document type Letter
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1111/ced.14365
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Book ; Online: Responsible AI in Healthcare

    Cabitza, Federico / Ciucci, Davide / Pasi, Gabriella / Viviani, Marco

    2022  

    Abstract: This article discusses open problems, implemented solutions, and future research in the area of responsible AI in healthcare. In particular, we illustrate two main research themes related to the work of two laboratories within the Department of ... ...

    Abstract This article discusses open problems, implemented solutions, and future research in the area of responsible AI in healthcare. In particular, we illustrate two main research themes related to the work of two laboratories within the Department of Informatics, Systems, and Communication at the University of Milano-Bicocca. The problems addressed concern, in particular, {uncertainty in medical data and machine advice}, and the problem of online health information disorder.

    Comment: 5 pages, 0 figures
    Keywords Computer Science - Computers and Society ; Computer Science - Artificial Intelligence ; Computer Science - Information Retrieval ; Computer Science - Machine Learning
    Publishing date 2022-02-19
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top