Article ; Online: Nutrition and bullous diseases.
2021 Volume 40, Issue 2, Page(s) 156–165
Abstract: Although relatively uncommon, autoimmune bullous diseases carry the risk of increased mortality and can significantly impact quality of life. This group of diseases is broad and encompasses subepidermal conditions such as bullous pemphigoid, cicatricial ... ...
Abstract | Although relatively uncommon, autoimmune bullous diseases carry the risk of increased mortality and can significantly impact quality of life. This group of diseases is broad and encompasses subepidermal conditions such as bullous pemphigoid, cicatricial pemphigoid, epidermolysis bullosa acquisita, dermatitis herpetiformis, and linear IgA bullous dermatosis, as well as intraepidermal conditions such as pemphigus and its variants. The pathophysiology of each condition is incompletely understood but broadly involves the formation of autoantibodies targeting skin adhesion proteins, a process that relies on a complex interplay between a dysregulated immune system, genetic predisposition, and environmental factors. We review the impact of nutrition on pathogenesis, clinical course, and treatment of various autoimmune bullous diseases. |
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MeSH term(s) | Autoimmune Diseases/drug therapy ; Epidermolysis Bullosa Acquisita/drug therapy ; Humans ; Pemphigoid, Bullous/drug therapy ; Pemphigoid, Bullous/etiology ; Pemphigus ; Quality of Life ; Skin Diseases, Vesiculobullous/drug therapy ; Skin Diseases, Vesiculobullous/etiology |
Language | English |
Publishing date | 2021-11-19 |
Publishing country | United States |
Document type | Journal Article ; Review |
ZDB-ID | 1064149-x |
ISSN | 1879-1131 ; 0738-081X |
ISSN (online) | 1879-1131 |
ISSN | 0738-081X |
DOI | 10.1016/j.clindermatol.2021.10.009 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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