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  1. Book: Probiotics

    Goldstein, Ellie J. C.

    added supplementary value in Clostridium difficile infection

    (Clinical infectious diseases ; 60, Suppl. 2)

    2015  

    Author's details guest ed.: Ellie J. C. Goldstein
    Series title Clinical infectious diseases ; 60, Suppl. 2
    Collection
    Language English
    Size S. S65 - S158 : graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place S.l.
    Publishing country United States
    Document type Book
    HBZ-ID HT018663926
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1505 -60,Suppl.2- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Periprosthetic Joint Infection.

    Parvizi, Javad / Schmidt, Michael G / Goldstein, Ellie J C

    The New England journal of medicine

    2023  Volume 388, Issue 15, Page(s) 1439

    MeSH term(s) Humans ; Prosthesis-Related Infections/surgery ; Arthroplasty, Replacement, Knee ; Arthroplasty, Replacement, Hip
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2302028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.34: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Microbiome-Related and Infection Control Approaches to Primary and Secondary Prevention of

    McFarland, Lynne V / Goldstein, Ellie J C / Kullar, Ravina

    Microorganisms

    2023  Volume 11, Issue 6

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    Language English
    Publishing date 2023-06-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11061534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Overcoming

    Kullar, Ravina / Wenzler, Eric / Alexander, Jose / Goldstein, Ellie J C

    Open forum infectious diseases

    2022  Volume 9, Issue 5, Page(s) ofac095

    Abstract: Stenotrophomonas ... ...

    Abstract Stenotrophomonas maltophilia
    Language English
    Publishing date 2022-03-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Lactobacillus

    Kullar, Ravina / Goldstein, Ellie J C / Johnson, Stuart / McFarland, Lynne V

    Microorganisms

    2023  Volume 11, Issue 4

    Abstract: Lactobacilli are widely found in nature, are commensal microbes in humans, and are commonly used as probiotics. Concerns about probiotic safety have arisen due to reports of bacteremia and ... ...

    Abstract Lactobacilli are widely found in nature, are commensal microbes in humans, and are commonly used as probiotics. Concerns about probiotic safety have arisen due to reports of bacteremia and other
    Language English
    Publishing date 2023-03-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11040896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Microbiome-Related and Infection Control Approaches to Primary and Secondary Prevention of Clostridioides difficile Infections

    Lynne V. McFarland / Ellie J. C. Goldstein / Ravina Kullar

    Microorganisms, Vol 11, Iss 1534, p

    2023  Volume 1534

    Abstract: Clostridioides difficile infections (CDIs) have decreased in the past years, but since 2021, some hospitals have reported an increase in CDI rates. CDI remains a global concern and has been identified as an urgent threat to healthcare. Although multiple ... ...

    Abstract Clostridioides difficile infections (CDIs) have decreased in the past years, but since 2021, some hospitals have reported an increase in CDI rates. CDI remains a global concern and has been identified as an urgent threat to healthcare. Although multiple treatment options are available, prevention strategies are more limited. As CDI is an opportunistic infection that arises after the normally protective microbiome has been disrupted, preventive measures aimed at restoring the microbiome have been tested. Our aim is to update the present knowledge on these various preventive strategies published in the past five years (2018–2023) to guide clinicians and healthcare systems on how to best prevent CDI. A literature search was conducted using databases (PubMed, Google Scholar, and clinicaltrials.gov) for phase 2–3 clinical trials for the primary or secondary prevention of CDI and microbiome and probiotics. As the main factor for Clostridium difficile infections is the disruption of the normally protective intestinal microbiome, strategies aimed at restoring the microbiome seem most rational. Some strains of probiotics, the use of fecal microbial therapy, and live biotherapeutic products offer promise to fill this niche; although, more large randomized controlled trials are needed that document the shifts in the microbiome population.
    Keywords C. difficile infections ; prevention ; live biological product ; probiotics ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  7. Article: Investigational Treatment Agents for Recurrent

    Kullar, Ravina / Tran, Mai-Chi N / Goldstein, Ellie J C

    Journal of experimental pharmacology

    2020  Volume 12, Page(s) 371–384

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    Language English
    Publishing date 2020-10-09
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2587465-2
    ISSN 1179-1454
    ISSN 1179-1454
    DOI 10.2147/JEP.S242959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Conference proceedings: New fluoroquinolones and anaerobic infections

    Goldstein, Ellie J. C.

    San Juan, Puerto Rico, 5 - 9 November 1995

    (Clinical infectious diseases ; 23, Suppl. 1)

    1996  

    Institution Symposium on Anaerobic Infections and New Quinolones
    Author's details [Symposium on Anaerobic Infections and New Quinolones.] Guest ed.: Ellie J. C. Goldstein
    Series title Clinical infectious diseases ; 23, Suppl. 1
    Collection
    Keywords Anti-Infective Agents, Fluoroquinolone / therapeutic use / congresses ; Bacterial Infections / drug therapy / congresses ; Bacteria, Anaerobic / congresses
    Language English
    Size S106 S. : Ill., graph. Darst.
    Publisher Univ. of Chicago Press
    Publishing place Chicago, Ill
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT007477568
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1505 -23,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  9. Article ; Online: Bacteroides and related species: The keystone taxa of the human gut microbiota.

    Shin, Jae Hyun / Tillotson, Glenn / MacKenzie, Tiffany N / Warren, Cirle A / Wexler, Hannah M / Goldstein, Ellie J C

    Anaerobe

    2024  Volume 85, Page(s) 102819

    Abstract: Microbial communities play a significant role in maintaining ecosystems in a healthy homeostasis. Presently, in the human gastrointestinal tract, there are certain taxonomic groups of importance, though there is no single species that plays a keystone ... ...

    Abstract Microbial communities play a significant role in maintaining ecosystems in a healthy homeostasis. Presently, in the human gastrointestinal tract, there are certain taxonomic groups of importance, though there is no single species that plays a keystone role. Bacteroides spp. are known to be major players in the maintenance of eubiosis in the human gastrointestinal tract. Here we review the critical role that Bacteroides play in the human gut, their potential pathogenic role outside of the gut, and their various methods of adapting to the environment, with a focus on data for B. fragilis and B. thetaiotaomicron. Bacteroides are anaerobic non-sporing Gram negative organisms that are also resistant to bile acids, generally thriving in the gut and having a beneficial relationship with the host. While they are generally commensal organisms, some Bacteroides spp. can be opportunistic pathogens in scenarios of GI disease, trauma, cancer, or GI surgery, and cause infection, most commonly intra-abdominal infection. B. fragilis can develop antimicrobial resistance through multiple mechanisms in large part due to its plasticity and fluid genome. Bacteroidota (formerly, Bacteroidetes) have a very broad metabolic potential in the GI microbiota and can rapidly adapt their carbohydrate metabolism to the available nutrients. Gastrointestinal Bacteroidota species produce short-chain fatty acids such as succinate, acetate, butyrate, and occasionally propionate, as the major end-products, which have wide-ranging and many beneficial influences on the host. Bacteroidota, via bile acid metabolism, also play a role in in colonization-resistance of other organisms, including Clostridioides difficile, and maintenance of gut integrity.
    MeSH term(s) Humans ; Bacteroides/genetics ; Gastrointestinal Microbiome ; Gastrointestinal Tract ; Microbiota ; Bile Acids and Salts/pharmacology
    Chemical Substances Bile Acids and Salts
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1237621-8
    ISSN 1095-8274 ; 1075-9964
    ISSN (online) 1095-8274
    ISSN 1075-9964
    DOI 10.1016/j.anaerobe.2024.102819
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4318: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article ; Online: In Vitro

    Goldstein, Ellie J C / Merriam, C Vreni / Citron, Diane M

    Antimicrobial agents and chemotherapy

    2020  Volume 64, Issue 9

    Abstract: Tedizolid's anaerobic activity is unappreciated. In this study, it was active against all 332 anaerobic isolates tested at ≤2 μg/ml ... ...

    Abstract Tedizolid's anaerobic activity is unappreciated. In this study, it was active against all 332 anaerobic isolates tested at ≤2 μg/ml except
    MeSH term(s) Anaerobiosis ; Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents/pharmacology ; Bacteria, Anaerobic ; Bacteroides fragilis ; Linezolid/pharmacology ; Microbial Sensitivity Tests ; Oxazolidinones ; Porphyromonas ; Prevotella ; Tetrazoles ; Veillonella
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents ; Oxazolidinones ; Tetrazoles ; tedizolid (97HLQ82NGL) ; Linezolid (ISQ9I6J12J)
    Language English
    Publishing date 2020-08-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/AAC.01088-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Einzelsignatur: Show issues

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