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Article ; Online: Raw veganism severe complication.

Coccolini, Federico / Tartaglia, Dario / Cremonini, Camilla / Cicuttin, Enrico / Chiarugi, Massimo

2021 Volume 91, Issue 12, Page(s) E757

MeSH term(s)	Diet, Vegan ; Humans
Language	English
Publishing date	2021-04-22
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2050749-5
ISSN	1445-2197 ; 1445-1433 ; 0004-8682
ISSN (online)	1445-2197
ISSN	1445-1433 ; 0004-8682
DOI	10.1111/ans.16877
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Article ; Online: Intraoperative transcystic laparoscopic common bile duct stone clearance with SpyGlass™ discover during emergency and elective cholecystectomy: a single-center case series.

Fugazzola, Paola / Bianchi, Carlo Maria / Calabretto, Francesca / Cicuttin, Enrico / Dal Mas, Francesca / Dominioni, Tommaso / Maestri, Marcello / Mauro, Aurelio / Podestà, Alice / Tomasoni, Matteo / Brucchi, Francesco / Viganò, Jacopo / Ansaloni, Luca / Anderloni, Andrea / Cobianchi, Lorenzo

World journal of emergency surgery : WJES

2024 Volume 19, Issue 1, Page(s) 8

Abstract: Background and study aim: The development of a new cholangioscope, the SpyGlass™ Discover (Boston Scientific), has allowed the laparoscopic transcystic common bile duct exploration and stone clearance. The possibility of simultaneous treatment of ... ...

Abstract	Background and study aim: The development of a new cholangioscope, the SpyGlass™ Discover (Boston Scientific), has allowed the laparoscopic transcystic common bile duct exploration and stone clearance. The possibility of simultaneous treatment of choledocholithiasis during early laparoscopic cholecystectomy offers the opportunity to enormously reduce the time between acute cholecystitis diagnosis and the execution of cholecystectomy with better outcomes for patients. Furthermore, an altered anatomy of the gastrointestinal tract is not an obstacle to this technique. The aim of the study was to determine whether this new procedure is feasible, safe, and effective. Patients and methods: The investigation employs a retrospective case series study including all consecutive patients with a diagnosis of common bile duct stones undergoing cholecystectomy and intraoperative laparoscopic common bile duct clearance using SpyGlass™ Discover at IRCCS Policlinico San Matteo in Pavia (Italy). Eighteen patients were included from May 2022 to May 2023. Results: A complete clearance of the common bile duct was obtained in 88.9% of patients. The mean postoperative length of stay was 3 days. No major complications occurred. After a median follow-up of 8 months, no recurrence of biliary events or readmissions occurred. Conclusion: This procedure has proven to be feasible, safe, and effective.
MeSH term(s)	Humans ; Retrospective Studies ; Cholecystectomy ; Laparoscopy ; Gallstones/surgery ; Common Bile Duct/surgery
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2233734-9
ISSN	1749-7922 ; 1749-7922
ISSN (online)	1749-7922
ISSN	1749-7922
DOI	10.1186/s13017-023-00529-0
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Article: The "Torment" of Surgical Antibiotic Prophylaxis among Surgeons.

Sartelli, Massimo / Coccolini, Federico / Carrieri, Angeloantonio / Labricciosa, Francesco M / Cicuttin, Enrico / Catena, Fausto

Antibiotics (Basel, Switzerland)

2021 Volume 10, Issue 11

Abstract: Surgical antibiotic prophylaxis (SAP) is one of the peri-operative measures for preventing surgical site infections (SSIs). Its goal is to counteract the proliferation of bacteria in the surgical site during intervention in order to reduce the risk of ... ...

Abstract	Surgical antibiotic prophylaxis (SAP) is one of the peri-operative measures for preventing surgical site infections (SSIs). Its goal is to counteract the proliferation of bacteria in the surgical site during intervention in order to reduce the risk of SSIs. SAP should be administered for surgical interventions where the benefit expected (prevention of SSIs) is higher compared to the risk (serious side effects, such as acute kidney injury,
Language	English
Publishing date	2021-11-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2681345-2
ISSN	2079-6382
ISSN	2079-6382
DOI	10.3390/antibiotics10111357
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Article ; Online: Laparoscopic versus open repair of perforated peptic ulcers: analysis of outcomes and identification of predictive factors of conversion.

Tartaglia, Dario / Strambi, Silvia / Coccolini, Federico / Mazzoni, Alessio / Miccoli, Mario / Cremonini, Camilla / Cicuttin, Enrico / Chiarugi, Massimo

Updates in surgery

2022 Volume 75, Issue 3, Page(s) 649–657

Abstract: Background: The surgical treatment for perforated peptic ulcers (PPUs) can be safely performed laparoscopically. This study aimed to compare the outcomes of patients who received different surgical approaches for PPU and to identify the predictive ... ...

Abstract	Background: The surgical treatment for perforated peptic ulcers (PPUs) can be safely performed laparoscopically. This study aimed to compare the outcomes of patients who received different surgical approaches for PPU and to identify the predictive factors for conversion to open surgery. Methods: This retrospective study analyzed patients treated for PPUs from 2002 to 2020. Three groups were identified: a complete laparoscopic surgery group (LG), a conversion to open group (CG), and a primary open group (OG). After univariate comparisons, a multivariate analysis was conducted to identify the predictive factors for conversion. Results: Of the 175 patients that underwent surgery for PPU, 104 (59.4%) received a laparoscopic-first approach, and 27 (25.9%) required a conversion to open surgery. Patients treated directly with an open approach were older (p < 0.0001), had more comorbidities (p < 0.0001), and more frequently had a previous laparotomy (p = 0.0001). In the OG group, in-hospital mortality and ICU need were significantly higher, while the postoperative stay was longer. Previous abdominal surgery (OR 0.086, 95% CI 0.012-0.626; p = 0.015), ulcer size (OR 0.045, 95% CI 0.010-0.210; p < 0.0001), and a posterior ulcer location (OR 0.015, 95% CI 0.001-0.400; p = 0.012) were predictive factors for conversion to an open approach. Conclusion: This study confirms the benefits of the laparoscopic approach for the treatment of PPUs. Previous laparotomies, a greater ulcer size, and a posterior location of the ulcer are risk factors for conversion to open surgery during laparoscopic repair.
MeSH term(s)	Humans ; Retrospective Studies ; Ulcer/complications ; Ulcer/surgery ; Peptic Ulcer Perforation/surgery ; Peptic Ulcer Perforation/etiology ; Risk Factors ; Laparoscopy/adverse effects ; Length of Stay ; Postoperative Complications/etiology ; Treatment Outcome
Language	English
Publishing date	2022-10-03
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2572692-4
ISSN	2038-3312 ; 2038-131X
ISSN (online)	2038-3312
ISSN	2038-131X
DOI	10.1007/s13304-022-01391-6
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Article ; Online: Comment on: Abdominal fluid samples (negative for SARS-CoV-2) from a critically unwell patient with respiratory COVID-19.

Coccolini, Federico / Cicuttin, Enrico / Cobianchi, Lorenzo / Pietrabissa, Andrea / Sartelli, Massimo / Catena, Fausto / Chiarugi, Massimo

The British journal of surgery

2020 Volume 107, Issue 12, Page(s) e623

MeSH term(s)	COVID-19 ; Humans ; Pandemics ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-09-19
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	2985-3
ISSN	1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
ISSN (online)	1365-2168
ISSN	0263-1202 ; 0007-1323 ; 1355-7688
DOI	10.1002/bjs.11899
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Article ; Online: Detect to protect: pneumoperitoneum gas samples for SARS-CoV-2 and biohazard testing.

Cicuttin, Enrico / Cobianchi, Lorenzo / Chiarugi, Massimo / Catena, Fausto / Coccolini, Federico / Pietrabissa, Andrea

Surgical endoscopy

2020 Volume 34, Issue 7, Page(s) 2863–2865

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Hazardous Substances ; Humans ; Laparoscopy ; Pandemics ; Pneumonia, Viral ; Pneumoperitoneum ; Severe acute respiratory syndrome-related coronavirus ; SARS-CoV-2 ; Smoke
Chemical Substances	Hazardous Substances ; Smoke
Keywords	covid19
Language	English
Publishing date	2020-05-04
Publishing country	Germany
Document type	Journal Article ; Comment
ZDB-ID	639039-0
ISSN	1432-2218 ; 0930-2794
ISSN (online)	1432-2218
ISSN	0930-2794
DOI	10.1007/s00464-020-07611-7
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Article ; Online: Antibiotic prophylaxis in trauma: Global Alliance for Infection in Surgery, Surgical Infection Society Europe, World Surgical Infection Society, American Association for the Surgery of Trauma, and World Society of Emergency Surgery guidelines.

Coccolini, Federico / Sartelli, Massimo / Sawyer, Robert / Rasa, Kemal / Ceresoli, Marco / Viaggi, Bruno / Catena, Fausto / Damaskos, Dimitrios / Cicuttin, Enrico / Cremonini, Camilla / Moore, Ernest E / Biffl, Walter L / Coimbra, Raul

The journal of trauma and acute care surgery

2023 Volume 96, Issue 4, Page(s) 674–682

Abstract: Abstract: Trauma is a complex disease, and the use of antibiotic prophylaxis (AP) in trauma patients is common practice. However, considering the increasing rates of antibiotic resistance, AP use should be questioned and limited only to specific cases. ... ...

Abstract	Abstract: Trauma is a complex disease, and the use of antibiotic prophylaxis (AP) in trauma patients is common practice. However, considering the increasing rates of antibiotic resistance, AP use should be questioned and limited only to specific cases. Antibiotic stewardship is of paramount importance in fighting resistance spread. Definitive rules or precise indications about AP in trauma remain unclear. The present article describes the indications of AP in traumatic lesions to the head, brain, torso, maxillofacial, extremities, skin, and soft tissues endorsed by the Global Alliance for Infection in Surgery, Surgical Infection Society Europe, World Surgical Infection Society, American Association for the Surgery of Trauma, and World Society of Emergency Surgery.
MeSH term(s)	Humans ; United States ; Antibiotic Prophylaxis ; Surgical Wound Infection/prevention & control ; Europe ; Anti-Bacterial Agents/therapeutic use
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2023-12-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2651070-4
ISSN	2163-0763 ; 2163-0755
ISSN (online)	2163-0763
ISSN	2163-0755
DOI	10.1097/TA.0000000000004233
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Article ; Online: Prospective validation of the Israeli Score for the prediction of common bile duct stones in patients with acute calculous cholecystitis.

Fugazzola, Paola / Cobianchi, Lorenzo / Dal Mas, Francesca / Cicuttin, Enrico / Dominioni, Tommaso / Frassini, Simone / Tomasoni, Matteo / Viganò, Jacopo / Catena, Fausto / Ansaloni, Luca

Surgical endoscopy

2023 Volume 37, Issue 11, Page(s) 8562–8569

Abstract: Background: Existing guidelines for predicting common bile duct stones (CBDS) are not specific for acute calculous cholecystitis (ACC). This paper is a posthoc analysis of the S.P.Ri.M.A.C.C study aiming to prospectively validate on a large independent ... ...

Abstract	Background: Existing guidelines for predicting common bile duct stones (CBDS) are not specific for acute calculous cholecystitis (ACC). This paper is a posthoc analysis of the S.P.Ri.M.A.C.C study aiming to prospectively validate on a large independent cohort of patients the Israeli Score (IS) in predicting CBDS in patients with ACC. Methods: The S.P.Ri.M.A.C.C. study is an observational multicenter prospective study endorsed by the World Society of Emergency Surgery (WSES). Between September 1st, 2021, and September 1st, 2022, 1201 participants were included. The Chi-Square test was used to compare categorical data. A Cochran-Armitage test was run to determine whether a linear trend existed between the IS and the presence of CBDS. To assess the accuracy of the prediction model, the receiver operating characteristic (ROC) curve was generated, and the area under the ROC curve (AUC) was calculated. Logistic regression was run to obtain Odds Ratio (OR). A two-tailed p < 0.05 was considered statistically significant. Results: The rate of CBDS was 1.8% in patients with an IS of 0, 4.2% in patients with an IS of 1, 24.5% in patients with 2 and 56.3% in patients with 3 (p < 0.001). The Cochran-Armitage test of trend showed a statistically significant linear trend, p < 0.001. Patients with an IS of 3 had 64.4 times (95% CI 24.8-166.9) higher odds of having associated CBDS than patients with an IS of 0. The AUC of the ROC curve of IS for the prediction of CBDS was 0.809 (95% CI 0.752-0.865, p < 0.001). By applying the highest cut-off point (3), the specificity reached 99%, while using the lowest cut-off value (0), the sensitivity reached 100%. Conclusion: The IS is a reliable tool to predict CBDS associated with ACC. The algorithm derived from the IS could optimize the management of patients with ACC.
MeSH term(s)	Humans ; Cholangiopancreatography, Endoscopic Retrograde ; Cholecystitis, Acute/complications ; Cholecystitis, Acute/diagnosis ; Choledocholithiasis/surgery ; Common Bile Duct/surgery ; Gallstones/complications ; Gallstones/surgery ; Israel ; Prospective Studies ; Retrospective Studies
Language	English
Publishing date	2023-10-04
Publishing country	Germany
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	639039-0
ISSN	1432-2218 ; 0930-2794
ISSN (online)	1432-2218
ISSN	0930-2794
DOI	10.1007/s00464-023-10442-x
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Article ; Online: Non-operative management in blunt splenic trauma

Serena Musetti / Federico Coccolini / Dario Tartaglia / Camilla Cremonini / Silvia Strambi / Enrico Cicuttin / Luigi Cobuccio / Ismail Cengeli / Giuseppe Zocco / Massimo Chiarugi

Emergency Care Journal, Vol 18, Iss

A ten-years-experience at a Level 1 Trauma Center

2022 Volume 1

Abstract: Trauma; Spleen injuries are among the most frequent trauma-related injuries. The approach for diagnosis and management of Blunt Splenic Injury (BSI) has been considerably shifted towards Non- Operative Management (NOM) in the last few decades. NOM of ... ...

Abstract	Trauma; Spleen injuries are among the most frequent trauma-related injuries. The approach for diagnosis and management of Blunt Splenic Injury (BSI) has been considerably shifted towards Non- Operative Management (NOM) in the last few decades. NOM of blunt splenic injuries includes Splenic Angio-Embolization (SAE). Aim of this study was to analyze Pisa Level 1 trauma center (Italy) last 10-years-experience in the management of Blunt Splenic Trauma (BST), and more specifically to evaluate NOM rate and failure. Retrospective analysis of all patients admitted with blunt splenic trauma was done. They were divided into two groups according to the treatment: hemodynamically unstable patients treated operatively (OM group) and patients underwent a nonoperative management (NOM group). The CT scan performed in all NOM group patients. Univariate analysis was performed to identify differences between the two groups. Multivariate analysis adjusting for factors with a p value < 0.05 or with clinical relevance was used to identify possible risk factors for NOM failure. 193 consecutive patients with blunt splenic trauma were admitted. Emergency splenectomies were performed in 53 patients (OM group); 140 were managed non-operatively with or without SAE (NOM group). NOM rate in high grade injuries is 57%. Overall NOM failure rate is 9%, and success rate in high grade splenic injuries is 48%; multivariate analysis showed AAST score ≥3 as a risk factor for NOM failure. Non-operative management currently represents the gold standard management for hemodynamically stable patient with blunt splenic trauma even in high grade splenic injuries. AAST ≥3 spleen lesion is a failure risk factor but not a contraindication to for non-operative management.
Keywords	Trauma ; spleen ; mortality ; morbidity ; classification ; results ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Detect to protect: pneumoperitoneum gas samples for SARS-CoV-2 and biohazard testing

Cicuttin, Enrico / Cobianchi, Lorenzo / Chiarugi, Massimo / Catena, Fausto / Coccolini, Federico / Pietrabissa, Andrea

Surg Endosc

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #165144
Database	COVID19

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