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  1. Article ; Online: Characterising respiratory infections among hospitalised children during the COVID-19 pandemic in southeastern China

    Bin Wu / Wei Lin / Huanhuan Huang

    BMJ Open, Vol 14, Iss

    a cross-sectional study of pathogens and clinical association

    2024  Volume 1

    Abstract: Objective Children with acute respiratory tract infections (ARTIs) pose significantly burden on healthcare facilities due to high hospitalisation rates and mortality. However, limited epidemiological and clinical characteristics data on ARTIs in ... ...

    Abstract Objective Children with acute respiratory tract infections (ARTIs) pose significantly burden on healthcare facilities due to high hospitalisation rates and mortality. However, limited epidemiological and clinical characteristics data on ARTIs in southeastern China during the COVID-19 pandemic exists.Design Cross-sectional.Setting Tertiary hospital associated with the First Affiliated Hospital, Fujian Medical University, China.Participants 1007 hospitalised children diagnosed with ARTIs, aged 30 days to 15 years, were enrolled in this study from 1 January 2020 to 31 December 2021.Outcome measure The primary outcomes are the rate of pathogen infections in children with ARTIs. Secondary outcomes are the description of risk factors associated with ARTIs in children.Results Of the 1007 enrolled children, 28.2%, 42.2%, 21.8% and 7.7% were diagnosed with upper respiratory tract infection, bronchopneumonia, bronchitis and pneumonia, respectively. Mycoplasma pneumoniae (MP) was the most prevalent pathogen (31.9%), followed by influenza B virus (IFVB; 29.1%) and influenza A virus (IFVA; 19.1%). The study found that children under 1 year old (older than 30 days: ORIFVB=12.50; ORMP=8.53), children aged 1–3 years (ORMP=1.62), the winter season (ORIFVA=1.36), the time from symptoms onset to hospitalisation (ORMP=1.10) and increased precipitation (ORLP=1.01) were high-risk factors for ARTIs.Conclusion This investigation offers significant insights into the prevalence and distribution of common pathogens among children experiencing ARTIs in the context of the COVID-19 pandemic. The discernment of high-risk factors linked to these pathogens enhances our understanding of the epidemiological characteristics of ARTIs in children.
    Keywords Medicine ; R
    Subject code 610
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Integrated Assessment of Water Environmental Health Risk through Drinking Water Ingestion in Lhasa River Basin: Quantitative Analysis and Environmental Significance.

    Qin, Huanhuan / Huang, Lixiang / Chen, Yiping

    Bulletin of environmental contamination and toxicology

    2023  Volume 110, Issue 5, Page(s) 90

    Abstract: An integrated assessment of water environmental health risk through drinking water ingestion in Lhasa River has been implemented. The health risks caused by different pollutants in different age groups (children, juvenile and adult groups) are in the ... ...

    Abstract An integrated assessment of water environmental health risk through drinking water ingestion in Lhasa River has been implemented. The health risks caused by different pollutants in different age groups (children, juvenile and adult groups) are in the order of 10
    MeSH term(s) Adult ; Child ; Humans ; Drinking Water/analysis ; Environmental Monitoring ; Rivers ; Water Pollutants, Chemical/analysis ; Risk Assessment ; Environmental Health ; Eating ; China
    Chemical Substances Drinking Water ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-05-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 6895-0
    ISSN 1432-0800 ; 0007-4861
    ISSN (online) 1432-0800
    ISSN 0007-4861
    DOI 10.1007/s00128-023-03730-8
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  3. Article ; Online: Efficient Discrimination of Hazardous Organophosphate Flame Retardants via Cataluminescence-Based Multidimensional Ratiometric Sensing.

    Gong, Zhengjun / Deng, Yi / Zheng, Binbin / Zhu, Huanhuan / Huang, Xiaoying

    Analytical chemistry

    2024  Volume 96, Issue 11, Page(s) 4544–4552

    Abstract: Emerging contaminants have recently evolved into a severe worldwide environmental issue. Organophosphate flame retardants (OPFRs) with neurotoxicity, genotoxicity, and reproductive and developmental toxicity are a class of notorious emerging contaminants ...

    Abstract Emerging contaminants have recently evolved into a severe worldwide environmental issue. Organophosphate flame retardants (OPFRs) with neurotoxicity, genotoxicity, and reproductive and developmental toxicity are a class of notorious emerging contaminants that cause great concern. The development of high-efficiency and portable sensors for rapid online monitoring of OPFRs has become the primary demand for the exploration of the environmental migration and transformation of OPFRs. In this work, interestingly, the cataluminescence (CTL) phenomenon of OPFRs is first observed, and an ingenious multidimensional ratiometric CTL sensing strategy is developed for the recognition of multiple OPFRs. Three characteristic ratios are extracted from the multipeak CTL spectral curves based on energy transfer of single Tb/Eu-modified MgO sensing material, and thus a novel three-dimensional (3D) code recognition could be mapped out. This obtained 3D coordinate is found to be a unique characteristic for a given OPFR, just like an exclusive person's ID number, which can successfully discriminate and detect 10 kinds of OPFR vapors, including homologous series and isomers. More importantly, CTL mechanism investigations for OPFRs demonstrate that OPFRs undergo a series of chemical reaction processes, e.g., oxidative pyrolysis and hydroxylation, and different high-energy excited intermediates are generated, which trigger discrepant energy-transfer efficiency toward rare earth ions, leading to multipeak spectral profiles. Briefly, this proposed CTL analytical platform for OPFRs recognition initiates a new sensing principle for the efficient identification of emerging contaminants and shows significant prospects on rapid on-site detection.
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c05333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Characterising respiratory infections among hospitalised children during the COVID-19 pandemic in southeastern China: a cross-sectional study of pathogens and clinical association.

    Huang, Huanhuan / Wu, Bin / Lin, Wei

    BMJ open

    2024  Volume 14, Issue 1, Page(s) e076824

    Abstract: Objective: Children with acute respiratory tract infections (ARTIs) pose significantly burden on healthcare facilities due to high hospitalisation rates and mortality. However, limited epidemiological and clinical characteristics data on ARTIs in ... ...

    Abstract Objective: Children with acute respiratory tract infections (ARTIs) pose significantly burden on healthcare facilities due to high hospitalisation rates and mortality. However, limited epidemiological and clinical characteristics data on ARTIs in southeastern China during the COVID-19 pandemic exists.
    Design: Cross-sectional.
    Setting: Tertiary hospital associated with the First Affiliated Hospital, Fujian Medical University, China.
    Participants: 1007 hospitalised children diagnosed with ARTIs, aged 30 days to 15 years, were enrolled in this study from 1 January 2020 to 31 December 2021.
    Outcome measure: The primary outcomes are the rate of pathogen infections in children with ARTIs. Secondary outcomes are the description of risk factors associated with ARTIs in children.
    Results: Of the 1007 enrolled children, 28.2%, 42.2%, 21.8% and 7.7% were diagnosed with upper respiratory tract infection, bronchopneumonia, bronchitis and pneumonia, respectively.
    Conclusion: This investigation offers significant insights into the prevalence and distribution of common pathogens among children experiencing ARTIs in the context of the COVID-19 pandemic. The discernment of high-risk factors linked to these pathogens enhances our understanding of the epidemiological characteristics of ARTIs in children.
    MeSH term(s) Infant ; Child ; Humans ; COVID-19/epidemiology ; Cross-Sectional Studies ; Child, Hospitalized ; Pandemics ; Respiratory Tract Infections/epidemiology ; China/epidemiology ; Mycoplasma pneumoniae ; Tertiary Care Centers
    Language English
    Publishing date 2024-01-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-076824
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  5. Article: Sex Pheromones of the Potato Tuber Moth (

    Pan, Huanhuan / Zhao, Hongyi / Ai, Likun / Huang, Jian / Chen, Yang

    Frontiers in chemistry

    2022  Volume 10, Page(s) 882400

    Abstract: The potato tuber moth ( ...

    Abstract The potato tuber moth (
    Language English
    Publishing date 2022-03-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2022.882400
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  6. Article ; Online: Revealing mitf functions and visualizing allografted tumor metastasis in colorless and immunodeficient Xenopus tropicalis.

    Ran, Rensen / Li, Lanxin / Xu, Tingting / Huang, Jixuan / He, Huanhuan / Chen, Yonglong

    Communications biology

    2024  Volume 7, Issue 1, Page(s) 275

    Abstract: Transparent immunodeficient animal models not only enhance in vivo imaging investigations of visceral organ development but also facilitate in vivo tracking of transplanted tumor cells. However, at present, transparent and immunodeficient animal models ... ...

    Abstract Transparent immunodeficient animal models not only enhance in vivo imaging investigations of visceral organ development but also facilitate in vivo tracking of transplanted tumor cells. However, at present, transparent and immunodeficient animal models are confined to zebrafish, presenting substantial challenges for real-time, in vivo imaging studies addressing specific biological inquiries. Here, we employed a mitf
    MeSH term(s) Animals ; Anura ; Cytoplasm ; Xenopus/genetics ; Zebrafish/genetics ; Microphthalmia-Associated Transcription Factor/genetics ; Microphthalmia-Associated Transcription Factor/metabolism
    Chemical Substances Microphthalmia-Associated Transcription Factor
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-024-05967-3
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  7. Article ; Online: Correction to: Dynamic changes in ambient PM

    Yu, Zengli / Liu, Hongyan / Liu, Xiaozhuan / Tao, Yuchang / Zhang, Xiaoan / Zhao, Xin / Chang, Hui / Huang, Jia / Zhao, Yuanfang / Zhang, Huanhuan / Huang, Cunrui

    Environmental science and pollution research international

    2024  Volume 31, Issue 10, Page(s) 16107

    Language English
    Publishing date 2024-01-20
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32166-8
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  8. Article ; Online: Implantable celecoxib nanofibers made by electrospinning: fabrication and characterization.

    Lu, Geng / Yang, Chuangzan / Chu, Kedi / Zhu, Yi / Huang, Sa / Zheng, Juying / Jia, Huanhuan / Li, Xiaofang / Ban, Junfeng

    Nanomedicine (London, England)

    2024  Volume 19, Issue 8, Page(s) 657–669

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Rats ; Animals ; Celecoxib/therapeutic use ; Nanofibers ; Quality of Life ; Osteoarthritis/drug therapy ; Static Electricity
    Chemical Substances Celecoxib (JCX84Q7J1L)
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2277839-1
    ISSN 1748-6963 ; 1743-5889
    ISSN (online) 1748-6963
    ISSN 1743-5889
    DOI 10.2217/nnm-2023-0314
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    Zs.A 6617: Show issues Location:
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  9. Article ; Online: Optimization of Construction Process and Determination of Intermediate Cable Forces for Composite Beam Cable-Stayed Bridge

    Ersen Huang / Hongjun Ke / Huanhuan Hu

    Applied Sciences, Vol 13, Iss 5738, p

    2023  Volume 5738

    Abstract: This paper presents a comprehensive study of the Xiangsizhou Bridge, a double-tower double-cable steel–concrete composite girder cable-stayed bridge located in Pingnan, Guangxi, China. A finite element model of the full-bridge spatial truss system was ... ...

    Abstract This paper presents a comprehensive study of the Xiangsizhou Bridge, a double-tower double-cable steel–concrete composite girder cable-stayed bridge located in Pingnan, Guangxi, China. A finite element model of the full-bridge spatial truss system was established using a dual main beam simulation of the steel–concrete composite girder. To obtain the initial reasonable bridge state, the minimum bending energy method was employed, followed by optimization of the state using the unknown load coefficient method to attain the final reasonable completion state. This paper proposes an innovative construction scheme for the erection of the main girders, which is designed to address the issue of excessive tensile stresses in the bridge deck slabs that can arise in conventional construction schemes. This scheme can save about 4 months of construction time and shorten the construction cycle of main beam erection by 60%. Furthermore, the study derived and verified a formula for the intermediate cable force during the construction process, which demonstrated its effectiveness. This study provides practical value for the design and construction of similar bridges.
    Keywords composite girder cable-stayed bridge ; numerical calculations ; finished bridge state ; construction optimization ; wet joint ; interim cable forces ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 690
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Endothelial Cell-Derived Cholesterol Crystals Promote Endothelial Inflammation in Early Atherogenesis.

    Wang, Xia / Fu, Wenxia / Zhou, Guo / Huo, Huanhuan / Shi, Xin / Wang, Hao / Wang, Yinghua / Huang, Xiying / Shen, Linghong / Li, Long / He, Ben

    Antioxidants & redox signaling

    2024  

    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1483836-9
    ISSN 1557-7716 ; 1523-0864
    ISSN (online) 1557-7716
    ISSN 1523-0864
    DOI 10.1089/ars.2023.0498
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5488: Show issues Location:
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