LIVIVO - Search results -

Search results

Result 1 - 10 of total 80

Search options

Article ; Online: Exploratory research on genetic polymorphisms associated with positive empathy and trait forgivingness among the Japanese.

Matsunaga, Masahiro / Ohtsubo, Yohsuke / Masuda, Takahiko / Noguchi, Yasuki / Yamasue, Hidenori / Ishii, Keiko

2023 Volume 44, Issue 8, Page(s) 506–516

Abstract: Objectives: Previous studies have indicated that good human relationships contribute significantly to subjective well-being. We recently focused on two important ways of developing good interpersonal relationships: positive empathy, which focuses on the ...

Abstract	Objectives: Previous studies have indicated that good human relationships contribute significantly to subjective well-being. We recently focused on two important ways of developing good interpersonal relationships: positive empathy, which focuses on the happiness of other people, and trait forgivingness, a tendency to forgive others. We novelly conducted an exploratory genome-wide association study (GWAS) to identify candidate gene polymorphisms associated with positive empathy and trait forgivingness among the Japanese. Material and methods: We for the first time identified several genetic polymorphisms associated with positive empathy and trait forgivingness through the GWAS based on a small sample population and relatively low threshold. We subsequently validated three genetic polymorphisms from these candidate genes using a real-time polymerase chain reaction system. Results: The results demonstrated that polymorphism in the vomeronasal type-1 receptor 1 (VN1R1) (rs61744949), a putative human pheromone receptor, is associated with positive empathy. In addition, genetic polymorphisms in the 5-hydroxytryptamine (serotonin) receptor 7 (HTR7: rs77843021) and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon (YWHAE: rs9908013), which are associated with dopamine and serotonin biosynthesis, are associated with trait forgivingness. Conclusion: This study novelly illustrated the influence of the genetic polymorphism in VN1R1 on positive empathy and that of genetic polymorphisms in HTR7 and YWHAE on trait forgivingness. It identified a relationship between previously unreported genetic polymorphisms and the necessary abilities for developing good human relationships. This will significantly impact future research on positive psychology and social psychology.
MeSH term(s)	Humans ; Empathy ; Genome-Wide Association Study ; Serotonin ; Japan ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide
Chemical Substances	Serotonin (333DO1RDJY)
Language	English
Publishing date	2023-12-22
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	135951-4
ISSN	2354-4716 ; 0172-780X
ISSN (online)	2354-4716
ISSN	0172-780X
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 2384: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Genomic Landscape of Endometrial, Ovarian, and Cervical Cancers in Japan from the Database in the Center for Cancer Genomics and Advanced Therapeutics.

Xi, Qian / Kage, Hidenori / Ogawa, Miho / Matsunaga, Asami / Nishijima, Akira / Sone, Kenbun / Kawana, Kei / Oda, Katsutoshi

Cancers

2023 Volume 16, Issue 1

Abstract: This study aimed to comprehensively clarify the genomic landscape and its association with tumor mutational burden-high (TMB-H, ≥10 mut/Mb) and microsatellite instability-high (MSI-H) in endometrial, cervical, and ovarian cancers. We obtained genomic ... ...

Abstract	This study aimed to comprehensively clarify the genomic landscape and its association with tumor mutational burden-high (TMB-H, ≥10 mut/Mb) and microsatellite instability-high (MSI-H) in endometrial, cervical, and ovarian cancers. We obtained genomic datasets of a comprehensive genomic profiling test, FoundationOne
Language	English
Publishing date	2023-12-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers16010136
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Double-Layered Perovskite Oxyfluoride Cathodes with High Capacity Involving O-O Bond Formation for Fluoride-Ion Batteries.

Miki, Hidenori / Yamamoto, Kentaro / Nakaki, Hiroyuki / Yoshinari, Takahiro / Nakanishi, Koji / Nakanishi, Shinji / Iba, Hideki / Miyawaki, Jun / Harada, Yoshihisa / Kuwabara, Akihide / Wang, Yanchang / Watanabe, Toshiki / Matsunaga, Toshiyuki / Maeda, Kazuhiko / Kageyama, Hiroshi / Uchimoto, Yoshiharu

Journal of the American Chemical Society

2024 Volume 146, Issue 6, Page(s) 3844–3853

Abstract: Developing electrochemical high-energy storage systems is of crucial importance toward a green and sustainable energy supply. A promising candidate is fluoride-ion batteries (FIBs), which can deliver a much higher volumetric energy density than lithium- ... ...

Abstract	Developing electrochemical high-energy storage systems is of crucial importance toward a green and sustainable energy supply. A promising candidate is fluoride-ion batteries (FIBs), which can deliver a much higher volumetric energy density than lithium-ion batteries. However, typical metal fluoride cathodes with conversion-type reactions cause a low-rate capability. Recently, layered perovskite oxides and oxyfluorides, such as LaSrMnO
Language	English
Publishing date	2024-01-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c10871
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 55/32: Show issues
Z 7.3: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Waning of Anti-SARS-CoV-2 Spike Antibody Levels 100 to 200 Days after the Second Dose of the BNT162b2 Vaccine.

Matsunaga, Hidenori / Takeuchi, Hidefumi / Oba, Yuichiro / Fujimi, Satoshi / Honda, Tomoyuki / Tomonaga, Keizo

Vaccines

2022 Volume 10, Issue 2

Abstract: Anti-SARS-CoV-2 antibodies of 444 vaccinated hospital employees in Japan were measured 94-109 days and 199-212 days after receiving the second BNT162b2 vaccine dose to evaluate the intensity and duration of antibody response in our own cohort. Among ... ...

Abstract	Anti-SARS-CoV-2 antibodies of 444 vaccinated hospital employees in Japan were measured 94-109 days and 199-212 days after receiving the second BNT162b2 vaccine dose to evaluate the intensity and duration of antibody response in our own cohort. Among uninfected participants, anti-S antibody levels were greatly decreased 199-212 days after the second vaccination compared to the levels measured 94-109 days after the second vaccination (median levels: 830 AU/mL and 2425 AU/mL, respectively;
Language	English
Publishing date	2022-01-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines10020177
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Huge Primary Cardiac Malignant Lymphoma in the Left Ventricle.

Matsunaga, Kazumasa / Kobayashi, Toshiro / Takahashi, Masaya / Gohra, Hidenori

The Annals of thoracic surgery

2020 Volume 110, Issue 2, Page(s) e115–e118

Abstract: A 67-year-old man presented at the hospital with worsening exertional dyspnea. Echocardiography showed a tumor in the left ventricle (approximately 35 × 48 mm) that protruded into the left atrium and left ventricular outflow tract during systole. These ... ...

Abstract	A 67-year-old man presented at the hospital with worsening exertional dyspnea. Echocardiography showed a tumor in the left ventricle (approximately 35 × 48 mm) that protruded into the left atrium and left ventricular outflow tract during systole. These findings suggested a high risk of sudden death resulting from aortic valve obstruction or tumor embolism. Surgical resection was performed. During the operation, the tumor was resected as completely as possible, together with part of the myocardium where it arose. Histopathologic examination showed diffuse large B-cell lymphoma. The patient received systemic chemotherapy and is alive after 1 year.
MeSH term(s)	Aged ; Heart Neoplasms/pathology ; Heart Neoplasms/surgery ; Heart Ventricles ; Humans ; Lymphoma, Large B-Cell, Diffuse/pathology ; Lymphoma, Large B-Cell, Diffuse/surgery ; Male ; Tumor Burden
Language	English
Publishing date	2020-02-06
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2019.12.052
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 252: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Ribavirin Treatment for Severe Schizophrenia with Anti-Borna Disease Virus 1 Antibodies 30 Years after Onset.

Matsunaga, Hidenori / Fukumori, Akio / Mori, Kohji / Morihara, Takashi / Sato, Shunsuke / Kitauchi, Kyoko / Yanagida, Kanta / Taguchi, Kazumi / Honda, Tomoyuki / Tomonaga, Keizo

Case reports in psychiatry

2023 Volume 2023, Page(s) 4899364

Abstract: Objective: Borna disease virus 1 (BoDV-1) was proven to cause fatal encephalitis in humans in 2018. However, the effects of persistent infections remain unclear. Here, we present the case of a 50-year-old woman with a 30-year history of severe ... ...

Abstract	Objective: Borna disease virus 1 (BoDV-1) was proven to cause fatal encephalitis in humans in 2018. However, the effects of persistent infections remain unclear. Here, we present the case of a 50-year-old woman with a 30-year history of severe schizophrenia, who was exposed to fleas from stray cats prior to disease onset, suggesting the possibility of zoonosis including BoDV-1 infection. The patient had experienced significant social impairment, thought deterioration, delusions, and hallucinations for more than 20 years. Method: A radioligand assay was used to test the patient for IgG and IgM antibodies against BoDV-1 nucleoprotein (N) and phosphoprotein (P). Based on the protocol for hepatitis C, we treated the patient with 400 mg/day ribavirin, which was later increased to 600 mg/day. Results: The serological examination revealed anti-BoDV-1 N IgG. Although only subtle changes were observed over the 24 weeks of treatment, the family noticed that the patient's Cotard delusions had disappeared 7 months after completing the treatment, accompanied by some improvements in the relationship with the family. Conclusion: Though definite proof was not obtained, this presumed suppression of BoDV-1 by ribavirin leading to improvements in Cotard syndrome-like symptoms suggests that intractable schizophrenia might be one of the BoDV-1 infection phenotypes. Further studies are needed to clarify the effect of persistent BoDV-1 infections in humans.
Language	English
Publishing date	2023-02-27
Publishing country	United States
Document type	Case Reports
ZDB-ID	2629914-8
ISSN	2090-6838 ; 2090-682X
ISSN (online)	2090-6838
ISSN	2090-682X
DOI	10.1155/2023/4899364
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Waning of Anti-SARS-CoV-2 Spike Antibody Levels 100 to 200 Days after the Second Dose of the BNT162b2 Vaccine

Hidenori Matsunaga / Hidefumi Takeuchi / Yuichiro Oba / Satoshi Fujimi / Tomoyuki Honda / Keizo Tomonaga

Vaccines, Vol 10, Iss 177, p

2022 Volume 177

Abstract: Anti-SARS-CoV-2 antibodies of 444 vaccinated hospital employees in Japan were measured 94–109 days and 199–212 days after receiving the second BNT162b2 vaccine dose to evaluate the intensity and duration of antibody response in our own cohort. Among ... ...

Abstract	Anti-SARS-CoV-2 antibodies of 444 vaccinated hospital employees in Japan were measured 94–109 days and 199–212 days after receiving the second BNT162b2 vaccine dose to evaluate the intensity and duration of antibody response in our own cohort. Among uninfected participants, anti-S antibody levels were greatly decreased 199–212 days after the second vaccination compared to the levels measured 94–109 days after the second vaccination (median levels: 830 AU/mL and 2425 AU/mL, respectively; p < 0.001). The rate of decrease between the two testing periods was lower in infected participants than in uninfected participants (median: 47.7% and 33.9%, respectively; p < 0.001). Anti-S antibody levels were significantly higher in females (median: females, 2546 AU/mL; males, 2041 AU/mL; p = 0.002 during the first test period). The peak body temperature after vaccination was higher in females than in males (median: females, 37.4 °C; males: 37.1 °C; p = 0.044). Older males tended to have lower antibody levels. In conclusion, the duration of the anti-S antibody response to the BNT162b2 vaccine was short-lived, particularly in males. Anti-S antibody levels of 1000 AU/mL or lower according to SARS-CoV-2 IgG II Quant (Abbott) might indicate insufficient prevention against the delta variant, and the majority of participants appeared to have lost their protection 200 days after vaccination.
Keywords	anti-SARS-CoV-2 spike antibody ; BNT162b2 vaccine ; sex-associated differences ; third antigen stimulation ; delta variant ; Medicine ; R
Subject code	590
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: A Genetic Variation in the Y Chromosome Among Modern Japanese Males Related to Several Physiological and Psychological Characteristics.

Matsunaga, Masahiro / Ohtsubo, Yohsuke / Masuda, Takahiko / Noguchi, Yasuki / Yamasue, Hidenori / Ishii, Keiko

Frontiers in behavioral neuroscience

2021 Volume 15, Page(s) 774879

Abstract: Previous studies in population genetics have proposed that the Y-chromosomal (Y-DNA) haplogroup D ancestor likely originated from Africa. The haplogroup D branch next started Out-of-Africa migration, rapidly expanded across Eurasia, and later diversified ...

Abstract	Previous studies in population genetics have proposed that the Y-chromosomal (Y-DNA) haplogroup D ancestor likely originated from Africa. The haplogroup D branch next started Out-of-Africa migration, rapidly expanded across Eurasia, and later diversified in East Asia. Y-DNA haplogroup D-M55, one of the branches of haplogroup D, is only found in modern Japanese males, suggesting that individuals with Y-DNA haplogroup D migrated from the Eurasian continent. Based on previous observations, Y-DNA haplogroup D is expected to be associated with some male characteristics including personality. Therefore, this study investigated whether the Y-DNA haplogroup D-M55 is associated with several physiological and psychological characteristics, including exploratory motivation and human relationship-related perception. We recruited Japanese young adult males and females and investigated the association between Y-DNA haplogroup D-M55, physiological [body mass index (BMI)], and several psychological parameters [perceived number of close friends, behavioral inhibition system/behavioral activation system (BIS/BAS), perceived happiness, and perceived loneliness]. The results indicated that males with haplogroup D-M55 had a higher BMI and more close friends, compared with non-carrier males. Additional multiple regression analyses, which tested the hypothesis that haplogroup D-M55 predicts BMI and perceived number of close friends, confirmed our hypothesis, even after controlling for the potentially confounding variables of age and sex. We also analyzed the gene-gene interaction between haplogroup D-M55 and an autosomal gene polymorphism associated with BMI and human relationships, such as the dopamine D2 receptor gene (
Language	English
Publishing date	2021-12-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2452960-6
ISSN	1662-5153
ISSN	1662-5153
DOI	10.3389/fnbeh.2021.774879
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Cultural differences in social support seeking: The mediating role of empathic concern.

Zheng, Shaofeng / Masuda, Takahiko / Matsunaga, Masahiro / Noguchi, Yasuki / Ohtsubo, Yohsuke / Yamasue, Hidenori / Ishii, Keiko

PloS one

2021 Volume 16, Issue 12, Page(s) e0262001

Abstract: Prior research has found that East Asians are less willing than Westerners to seek social support in times of need. What factors account for this cultural difference? Whereas previous research has examined the mediating effect of relational concern, we ... ...

Abstract	Prior research has found that East Asians are less willing than Westerners to seek social support in times of need. What factors account for this cultural difference? Whereas previous research has examined the mediating effect of relational concern, we predicted that empathic concern, which refers to feeling sympathy and concern for people in need and varies by individuals from different cultures, would promote support seeking. We tested the prediction in two studies. In Study 1, European Canadians reported higher empathic concern and a higher frequency of support seeking, compared to the Japanese participants. As predicted, cultural differences in social support seeking were influenced by empathic concern. In Study 2, both empathic concern and relational concern mediated cultural differences in support seeking. Japanese with lower empathic concern but higher relational concern were more reluctant than European Americans to seek social support during stressful times. Finally, loneliness, which was more prevalent among the Japanese than among the European Americans, was partially explained by social support seeking.
MeSH term(s)	Adolescent ; Adult ; Canada/ethnology ; Cross-Cultural Comparison ; Cultural Characteristics ; Culture ; Emotions ; Empathy ; Europe/ethnology ; Female ; Humans ; Japan/ethnology ; Loneliness ; Male ; Social Support ; Stress, Psychological ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2021-12-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0262001
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Association between instrumental activities of daily living with the change in left ventricular function in older patients with cardiovascular disease.

Kariya, Hidenori / Yamaoka-Tojo, Minako / Obara, Shinichi / Noda, Chiharu / Matsunaga, Atsuhiko / Ako, Junya

Heart and vessels

2021 Volume 36, Issue 9, Page(s) 1298–1305

Abstract: Left ventricular dysfunction is a pathophysiologic characteristic of heart failure. Impaired instrumental activities of daily living are associated with an elevated risk of mortality and heart failure in older adults. Nevertheless, the relationship ... ...

Abstract	Left ventricular dysfunction is a pathophysiologic characteristic of heart failure. Impaired instrumental activities of daily living are associated with an elevated risk of mortality and heart failure in older adults. Nevertheless, the relationship between these activities and left ventricular function changes remains unclear. We determined whether instrumental activities of daily living are associated with subsequent left ventricular function changes in older cardiovascular disease patients. This retrospective cohort study included 383 outpatients with cardiovascular disease (74.5 ± 5.3 years, 273 males). Patients were divided according to the Frenchay activities index tertile and followed for six months after cardiovascular disease diagnosis. The left ventricular ejection fraction and annular early diastolic velocity (e') were measured for left ventricular systolic and diastolic function, respectively, at baseline and after one year. After adjusting for confounders, changes in the left ventricular ejection fraction were not significantly different. However, changes in the e' in the highest tertile group were significantly greater than in other groups. In the general linear model with multiple regression analysis, Frenchay activities index independently predicted the absolute change in the e'. In older cardiovascular disease patients, higher instrumental activities of daily living were associated with preserved left ventricular relaxation.
MeSH term(s)	Activities of Daily Living ; Aged ; Cardiovascular Diseases/diagnosis ; Diastole ; Female ; Heart Failure/diagnosis ; Humans ; Male ; Retrospective Studies ; Stroke Volume ; Ventricular Dysfunction, Left/diagnosis ; Ventricular Function, Left
Language	English
Publishing date	2021-03-08
Publishing country	Japan
Document type	Journal Article
ZDB-ID	89678-0
ISSN	1615-2573 ; 0910-8327 ; 0935-736X
ISSN (online)	1615-2573
ISSN	0910-8327 ; 0935-736X
DOI	10.1007/s00380-021-01812-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2049: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito