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  1. Article: Polymer - Nanoparticle Assemblies for Array Based Sensing.

    Creran, Brian / Bunz, Uwe H F / Rotello, Vincent M

    Current organic chemistry

    2014  Volume 109, Issue 12, Page(s) 1054–1062

    Abstract: Sensing clinically relevant biomolecules is crucial for the detection and prevention of disease. Currently used detection methods tend to be expensive, time intensive, and specific for only one particular biomolecule of interest. Nanoparticle-based ... ...

    Abstract Sensing clinically relevant biomolecules is crucial for the detection and prevention of disease. Currently used detection methods tend to be expensive, time intensive, and specific for only one particular biomolecule of interest. Nanoparticle-based arrays using conjugated polymers have emerged as an analytical and potential clinical tool, allowing detection of a wide range of biomolecules using selective, not specific, sensor components. In this report, we highlight recent progress in nanoparticle - polymer sensor arrays in both the fundamental understanding of how the sensor arrays function as well as the detection of clinically relevant bacteria and cells.
    Language English
    Publishing date 2014-11-24
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1385-2728
    ISSN 1385-2728
    DOI 10.2174/1385272819666150318221301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Gold nanoparticles: preparation, properties, and applications in bionanotechnology.

    Yeh, Yi-Cheun / Creran, Brian / Rotello, Vincent M

    Nanoscale

    2011  Volume 4, Issue 6, Page(s) 1871–1880

    Abstract: Gold nanoparticles (AuNPs) are important components for biomedical applications. AuNPs have been widely employed for diagnostics, and have seen increasing use in the area of therapeutics. In this mini-review, we present fabrication strategies for AuNPs ... ...

    Abstract Gold nanoparticles (AuNPs) are important components for biomedical applications. AuNPs have been widely employed for diagnostics, and have seen increasing use in the area of therapeutics. In this mini-review, we present fabrication strategies for AuNPs and highlight a selection of recent applications of these materials in bionanotechnology.
    MeSH term(s) Biotechnology/methods ; Gold/therapeutic use ; Nanocapsules/therapeutic use ; Nanomedicine/methods
    Chemical Substances Nanocapsules ; Gold (7440-57-5)
    Language English
    Publishing date 2011-11-10
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/c1nr11188d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Triggered Nanoparticles as Therapeutics.

    Kim, Chang Soo / Duncan, Bradley / Creran, Brian / Rotello, Vincent M

    Nano today

    2013  Volume 8, Issue 4, Page(s) 439–447

    Abstract: Drug delivery systems (DDSs) face several challenges including site-specific delivery, stability, and the programmed release of drugs. Engineered nanoparticle (NP) surfaces with responsive moieties can enhance the efficacy of DDSs ... ...

    Abstract Drug delivery systems (DDSs) face several challenges including site-specific delivery, stability, and the programmed release of drugs. Engineered nanoparticle (NP) surfaces with responsive moieties can enhance the efficacy of DDSs for
    Language English
    Publishing date 2013-09-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2224882-1
    ISSN 1878-044X ; 1748-0132
    ISSN (online) 1878-044X
    ISSN 1748-0132
    DOI 10.1016/j.nantod.2013.07.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Dopamine coated Fe

    Mumtaz, Shazia / Wang, Li-Sheng / Hussain, Syed Zajif / Abdullah, Muhammad / Huma, Zille / Iqbal, Zafar / Creran, Brian / Rotello, Vincent M / Hussain, Irshad

    Chemical communications (Cambridge, England)

    2017  Volume 53, Issue 91, Page(s) 12306–12308

    Abstract: We report a simple and economical colorimetric bacterial sensing strategy with catalytic amplification using dopamine-capped iron oxide (Dop- ... ...

    Abstract We report a simple and economical colorimetric bacterial sensing strategy with catalytic amplification using dopamine-capped iron oxide (Dop-Fe
    MeSH term(s) Bacillus subtilis/isolation & purification ; Biosensing Techniques ; Catalysis ; Colorimetry ; Dopamine/chemistry ; Escherichia coli/isolation & purification ; Magnetite Nanoparticles/chemistry ; Particle Size ; Spectrophotometry
    Chemical Substances Magnetite Nanoparticles ; Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2017-11-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/c7cc07149c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Array-based sensing with nanoparticles: 'chemical noses' for sensing biomolecules and cell surfaces.

    Miranda, Oscar R / Creran, Brian / Rotello, Vincent M

    Current opinion in chemical biology

    2010  Volume 14, Issue 6, Page(s) 728–736

    Abstract: Nanoparticle-based arrays have been used to distinguish a wide range of biomolecular targets through pattern recognition. In this report, we highlight new 'chemical nose' methodologies that use nanoparticle systems to provide high sensitivity sensing of ... ...

    Abstract Nanoparticle-based arrays have been used to distinguish a wide range of biomolecular targets through pattern recognition. In this report, we highlight new 'chemical nose' methodologies that use nanoparticle systems to provide high sensitivity sensing of biomolecular targets, including fluorescent polymer/gold nanoparticle complexes that can discriminate between different bioanalytes including proteins, bacteria, and mammalian cells as well as dye-based micellar systems for the detection of clinically important metalloproteins and nonmetalloproteins.
    MeSH term(s) Animals ; Biosensing Techniques/methods ; Cell Membrane/chemistry ; Humans ; Metal Nanoparticles/analysis ; Metal Nanoparticles/chemistry ; Metalloproteins/chemistry
    Chemical Substances Metalloproteins
    Language English
    Publishing date 2010-08-28
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ZDB-ID 1439176-4
    ISSN 1879-0402 ; 1367-5931
    ISSN (online) 1879-0402
    ISSN 1367-5931
    DOI 10.1016/j.cbpa.2010.07.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: Detection of bacteria using inkjet-printed enzymatic test strips.

    Creran, Brian / Li, Xiaoning / Duncan, Bradley / Kim, Chang Soo / Moyano, Daniel F / Rotello, Vincent M

    ACS applied materials & interfaces

    2014  Volume 6, Issue 22, Page(s) 19525–19530

    Abstract: Low-cost diagnostics for drinking water contamination have the potential to save millions of lives. We report a method that uses inkjet printing to copattern an enzyme-nanoparticle sensor and substrate on a paper-based test strip for rapid detection of ... ...

    Abstract Low-cost diagnostics for drinking water contamination have the potential to save millions of lives. We report a method that uses inkjet printing to copattern an enzyme-nanoparticle sensor and substrate on a paper-based test strip for rapid detection of bacteria. A colorimetric response is generated on the paper substrate that allows visual detection of contamination without the need for expensive instrumentation. These strips demonstrate a viable nanomanufacturing strategy for low-cost bacterial detection.
    MeSH term(s) Bacteria/isolation & purification ; Colorimetry ; Drinking Water/analysis ; Humans ; Nanoparticles/chemistry ; Printing ; Water Pollution
    Chemical Substances Drinking Water
    Language English
    Publishing date 2014-10-30
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/am505689g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Detection of Bacteria Using Inkjet-Printed Enzymatic Test Strips

    Creran, Brian / Li, Xiaoning / Duncan, Bradley / Kim, Chang Soo / Moyano, Daniel F / Rotello, Vincent M

    ACS Applied Materials & Interfaces. 2014 Nov. 26, v. 6, no. 22

    2014  

    Abstract: Low-cost diagnostics for drinking water contamination have the potential to save millions of lives. We report a method that uses inkjet printing to copattern an enzyme–nanoparticle sensor and substrate on a paper-based test strip for rapid detection of ... ...

    Abstract Low-cost diagnostics for drinking water contamination have the potential to save millions of lives. We report a method that uses inkjet printing to copattern an enzyme–nanoparticle sensor and substrate on a paper-based test strip for rapid detection of bacteria. A colorimetric response is generated on the paper substrate that allows visual detection of contamination without the need for expensive instrumentation. These strips demonstrate a viable nanomanufacturing strategy for low-cost bacterial detection.
    Keywords bacteria ; colorimetry ; diagnostic techniques ; instrumentation ; microbial detection ; rapid methods ; water pollution
    Language English
    Dates of publication 2014-1126
    Size p. 19525-19530.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1944-8252
    DOI 10.1021%2Fam505689g
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Laser desorption ionization mass spectrometric imaging of mass barcoded gold nanoparticles for security applications.

    Creran, Brian / Yan, Bo / Moyano, Daniel F / Gilbert, Michael M / Vachet, Richard W / Rotello, Vincent M

    Chemical communications (Cambridge, England)

    2012  Volume 48, Issue 38, Page(s) 4543–4545

    Abstract: Patterns created by the inkjet printing of functionalized gold nanoparticles (NPs) can be selectively detected by laser desorption/ionization imaging mass spectrometry (LDI-IMS). These patterns can only be visualized by mass, providing a robust yet ... ...

    Abstract Patterns created by the inkjet printing of functionalized gold nanoparticles (NPs) can be selectively detected by laser desorption/ionization imaging mass spectrometry (LDI-IMS). These patterns can only be visualized by mass, providing a robust yet tunable system for potential anti-counterfeiting applications.
    Language English
    Publishing date 2012-05-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/c2cc30499f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Colorimetric protein sensing using catalytically amplified sensor arrays.

    Li, Xiaoning / Wen, Fang / Creran, Brian / Jeong, Youngdo / Zhang, Xinrong / Rotello, Vincent M

    Small (Weinheim an der Bergstrasse, Germany)

    2012  Volume 8, Issue 23, Page(s) 3589–3592

    Abstract: Catalytically active iron oxide nanoparticles are used as recognition elements and signal amplifiers for the array-based colorimetric sensing of proteins. Interactions between cationic monolayers on the Fe(3) O(4) NPs and analyte proteins differentially ...

    Abstract Catalytically active iron oxide nanoparticles are used as recognition elements and signal amplifiers for the array-based colorimetric sensing of proteins. Interactions between cationic monolayers on the Fe(3) O(4) NPs and analyte proteins differentially modulates the peroxidase-like activity of Fe(3) O(4) NPs, affording catalytically amplified colorimetric signal patterns that enable the detection and identification of proteins at 50 nM.
    MeSH term(s) Biosensing Techniques ; Catalysis ; Colorimetry/methods ; Ferric Compounds/chemistry ; Nanoparticles/chemistry ; Peroxidase/chemistry ; Peroxidase/metabolism ; Proteins/analysis ; Proteins/chemistry
    Chemical Substances Ferric Compounds ; Proteins ; ferric oxide (1K09F3G675) ; Peroxidase (EC 1.11.1.7)
    Language English
    Publishing date 2012-09-07
    Publishing country Germany
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.201201549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Gradient and Patterned Protein Films Stabilized via Nanoimprint Lithography for Engineered Interactions with Cells.

    Wang, Li-Sheng / Duncan, Bradley / Tang, Rui / Lee, Yi-Wei / Creran, Brian / Elci, Sukru Gokhan / Zhu, Jiaxin / Yesilbag Tonga, Gülen / Doble, Jesse / Fessenden, Matthew / Bayat, Mahin / Nonnenmann, Stephen / Vachet, Richard W / Rotello, Vincent M

    ACS applied materials & interfaces

    2017  Volume 9, Issue 1, Page(s) 42–46

    Abstract: Protein-based biomaterials provide versatile scaffolds for generating functional surfaces for biomedical applications. However, tailoring the functional and biological properties of protein films remains a challenge. Here, we describe a high-throughput ... ...

    Abstract Protein-based biomaterials provide versatile scaffolds for generating functional surfaces for biomedical applications. However, tailoring the functional and biological properties of protein films remains a challenge. Here, we describe a high-throughput method to designing stable, functional biomaterials by combining inkjet deposition of protein inks with a nanoimprint lithography based methodology. The translation of the intrinsically charged proteins into functional materials properties was demonstrated through controlled cellular adhesion. This modular strategy offers a rapid method to produce customizable biomaterials.
    Language English
    Publishing date 2017--11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.6b13815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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