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Article ; Online: A case of cutaneous candidiasis of upper eyelid in association with facial paralysis.

Aytogan, Hasan

2020 Volume 68, Issue 4, Page(s) 637–638

MeSH term(s)	Candidiasis/complications ; Candidiasis/diagnosis ; Eyelid Diseases/complications ; Eyelid Diseases/diagnosis ; Eyelids ; Facial Paralysis/complications ; Facial Paralysis/diagnosis ; Humans
Language	English
Publishing date	2020-02-15
Publishing country	India
Document type	Case Reports ; Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_1381_19
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Article ; Online: Effect of corneal marking features on toric intraocular lens alignment.

Aytogan, Hasan

International ophthalmology

2020 Volume 40, Issue 7, Page(s) 1653–1658

Abstract: Purpose: The purpose of this study was to investigate the relation of the corneal ink mark size, shape, and location with the corneal perimeter in terms of the corresponding corneal axis.: Material and methods: This study was designed both ... ...

Abstract	Purpose: The purpose of this study was to investigate the relation of the corneal ink mark size, shape, and location with the corneal perimeter in terms of the corresponding corneal axis. Material and methods: This study was designed both prospective experimental and literature search. Contact lenses were used to demonstrate the spreading effect of the surgical ink mark. Open-access published corneal images with corneal ink marks were reviewed. Mark size and perimeter of both contact lenses and corneal images were performed in Image J software. Results: Twenty contact lenses and 15 corneal images with 32 corneal marks, which were obtained from the literature, were included in the study. Mean degree corresponding to the ink size for the group 1 was 8.3° ± 1.2° (range 5.5-10.3), for group 2 was 11° ± 1.1° (range 8-12), for group 3 was 4.2° ± 0.7° (range 3.2-5.5), for group 4 was 4.2° ± 0.7° (range 3.2-5.5), and for group 5 was 6.3° ± 2.5° (range 2-11.5). Discussion: Theoretically, it is wise to target further located ink mark from central cornea based on the 360/2π × (r2 - r1)/(r1 × r2) × M formula. It has been experimentally shown that the smaller corneal perimeter and closer mark to the central cornea may lead the more significant deviation from the targeted axis. Preoperative manual corneal marking may be more responsible for residual astigmatism than it is thought.
MeSH term(s)	Astigmatism/surgery ; Cornea/surgery ; Humans ; Lens Implantation, Intraocular ; Lenses, Intraocular ; Phacoemulsification ; Prospective Studies ; Refraction, Ocular
Language	English
Publishing date	2020-03-19
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	800087-6
ISSN	1573-2630 ; 0165-5701
ISSN (online)	1573-2630
ISSN	0165-5701
DOI	10.1007/s10792-020-01333-4
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Article ; Online: Evaluation of the relationship between tear meniscus changes and quality of life outcomes after external dacryocystorhinostomy.

Doran, Mehmet Ali / Ayintap, Emre / Aytogan, Hasan

International ophthalmology

2024 Volume 44, Issue 1, Page(s) 105

Abstract: Purpose: This study aims to investigate the effects of external dacryocystorhinostomy (DCR) surgery on tear meniscus parameters and assess its relationship with improvements in quality of life (QoL) in patients with nasolacrimal duct obstruction (NLDO).! ...

Abstract	Purpose: This study aims to investigate the effects of external dacryocystorhinostomy (DCR) surgery on tear meniscus parameters and assess its relationship with improvements in quality of life (QoL) in patients with nasolacrimal duct obstruction (NLDO). Methods: This prospective study included 30 patients diagnosed with NLDO who underwent external DCR surgery. Tear meniscus (TM) parameters, including height, depth and area, were measured using anterior segment optical coherence tomography. Lacrimal symptom questionnaire (LacQ), Munk scores and Glasgow benefit inventories (GBI) were collected. Statistical analysis was performed to evaluate the correlation between tear meniscus changes and improvements in QoL. Results: TM height, depth and area decreased from preoperative median measurements (0.09 mm Conclusion: External DCR surgery leads to significant improvements in tear meniscus parameters and quality of life outcomes in patients with NLDO. The decreased in TM height and TM area indicates improved tear film dynamics and decreased tear volume, which positively impact the patients' ocular comfort and overall well-being. This study highlights the importance of tear meniscus evaluation as a potential market for assessing the success of DCR surgery and its impact on patients' QoL.
MeSH term(s)	Humans ; Dacryocystorhinostomy/methods ; Lacrimal Duct Obstruction/diagnosis ; Quality of Life ; Nasolacrimal Duct/surgery ; Prospective Studies ; Meniscus
Language	English
Publishing date	2024-02-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	800087-6
ISSN	1573-2630 ; 0165-5701
ISSN (online)	1573-2630
ISSN	0165-5701
DOI	10.1007/s10792-024-03038-4
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Article ; Online: Understanding the Etiopathogenesis of Non-Arteritic Anterior Ischemic Optic Neuropathy with Laboratory Findings.

Uzakgider, Neslisah Kutlu / Karaca Adiyeke, Seda / Aytogan, Hasan

Beyoglu eye journal

2024 Volume 9, Issue 1, Page(s) 8–13

Abstract: Objectives: The role of inflammation and hemostasis in non-arteritic anterior ischemic optic neuropathy (NAION) was investigated by examining related blood tests. The predictive values of these laboratory indicators and their effects on prognosis were ... ...

Abstract	Objectives: The role of inflammation and hemostasis in non-arteritic anterior ischemic optic neuropathy (NAION) was investigated by examining related blood tests. The predictive values of these laboratory indicators and their effects on prognosis were reviewed. Methods: In this study, 48 patients diagnosed with NAION and 50 healthy volunteers were included. All subjects underwent full ophthalmological examination. All patients were treated with oral corticosteroids (methylprednisolone 1 mg/kg/day) for 15 days after that corticosteroid medication was reduced and stopped. Each patient was monitored at least for 12 months. The mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), and red cell distribution width (RDW) values were recorded. These findings were compared with control group. Results: The mean MPV, RDW, and NLR values were significantly higher in NAION group (respectively, p<0.001, p=0.006, and p<0.001). There was no statistically significant difference between group 1 and group 2 in PDW values, but the mean PDW value was higher in the patient group compared to the control group (p=0.435). Based on the receiver operating characteristic (ROC) curve, the NLR had the strongest predictive value. This was followed by MPV, RDW, and PDW with lower diagnostic predictive values. Conclusion: MPV, NLR, and RDW were found to be elevated and have diagnostic predictive values in NAION patients. Easily accessible and simple laboratory methods could help us show systemic inflammation and ischemic events in NAION patients. As a result, inflammatory reactions besides ischemic changes may play a role in the etiopathogenesis of NAION. These biomarkers can be evaluated to ensure that patients with risk factors for the development of NAION.
Language	English
Publishing date	2024-03-01
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	3031466-5
ISSN	2587-0394 ; 2459-1777
ISSN (online)	2587-0394
ISSN	2459-1777
DOI	10.14744/bej.2023.09815
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Article ; Online: Comparing the symmetry of upper eyelid following unilateral ptosis correction.

Aytogan, Hasan / Ayıntap, Emre

BMC ophthalmology

2021 Volume 21, Issue 1, Page(s) 438

Abstract: Background: Margin Reflex Distance 1(MRD 1) only describes the central height of upper eyelid and relies on the examiner's experience and disregards eyelid contour abnormalities. Therefore MRD 1 may not be sufficient for an acceptable result to evaluate ...

Abstract	Background: Margin Reflex Distance 1(MRD 1) only describes the central height of upper eyelid and relies on the examiner's experience and disregards eyelid contour abnormalities. Therefore MRD 1 may not be sufficient for an acceptable result to evaluate the outcomes of ptosis surgery. The primary purpose of this study was to assess outcomes of unilateral ptosis correction based on parameters including degree of symmetry, MRD 1, peak height of the upper lid, temporal and nasal ocular surface area, and temporal/nasal area ratio with an objective, quantitative, and repeatable method. Methods: This study was designed as a retrospective non-randomized case-control study. Medical records of the patients with unilateral ptosis between October 2015 and December 2020 were reviewed. Patients with unilateral ptosis who underwent surgical correction and levator function of 5 mm or greater were included in the study. Two groups were defined; ptotic eye was case group and contralateral eye was control group. Data analysis was performed Image J and Matlab softwares. Results: Thirty-four patients were included in the study. Mean age of patients was 58.8 ± 12.7 years (range 15-75 years). Mean follow-up time was 19.5 ± 7.3 months (range 8-40 months). Four patients were diagnosed with congenital ptosis and 30 patients aponeurotic ptosis. Mean preoperative degree of symmetry for overall eyelid contour was 36.6 ± 27.5% (range 1-92%). Mean postoperative degree of symmetry for overall eyelid contour was 72.4 ± 16.5% (range 55-92%). Temporal/Nasal (T/N) area ratios for contralateral normal eye was 1.19 pre-postoperative, and it was 1.11 preoperatively, 1.15 postoperatively for operated ptotic eye. Conclusions: This study primarily demonstrated a quantitative, objective, and repeatable method to investigate the degree of symmetry after eyelid surgeries. Secondly, this study suggested that T/N ratio may not be a reliable parameter to evaluate the eyelid symmetry.
MeSH term(s)	Adolescent ; Adult ; Aged ; Case-Control Studies ; Eyelids/surgery ; Humans ; Middle Aged ; Retrospective Studies ; Young Adult
Language	English
Publishing date	2021-12-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2050436-6
ISSN	1471-2415 ; 1471-2415
ISSN (online)	1471-2415
ISSN	1471-2415
DOI	10.1186/s12886-021-02208-7
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Article ; Online: Outcomes of External Dacryocystorhinostomy under General and Local Anesthetics in a Tertiary Clinic.

Aytogan, Hasan / Doran, Mehmet Ali / Ayintap, Emre

Beyoglu eye journal

2022 Volume 7, Issue 1, Page(s) 25–29

Abstract: Objectives: In our clinic, although we prefer to perform dacryocystorhinostomy (DCR) under general anesthetics, we also perform it under local anesthetics for patients with a high risk of general anesthesia. Herein this study, we aimed to present our ... ...

Abstract	Objectives: In our clinic, although we prefer to perform dacryocystorhinostomy (DCR) under general anesthetics, we also perform it under local anesthetics for patients with a high risk of general anesthesia. Herein this study, we aimed to present our experiences in external DCR under both general and local anesthetics in a tertiary clinic. Methods: Medical records of the patients who had epiphora, were followed up in the oculoplastic section between January 2014 and December 2020 were collected. Patients who underwent external DCR were included in the study. Patients were divided into two groups: local and general anesthesia. All demographic characteristics of patients, previous DCR, history of dacryocystitis, surgery time, perioperative complications, and the American Society of Anaesthesiology (ASA) physical status score were recorded. Results: A total of 106 eyes from 82 patients were included in the study. The mean age of the patients was 57±24 years (range 18-89) and the median age was 56. Of 82 patients, 49 were female and 33 were male. 24 patients underwent bilateral external DCR. The mean surgery time for the general group and the local group was 66±12 min and 52±7 min, respectively. A significant difference was observed between the general and local groups in terms of the duration of the surgery (p=0.03). Of these, 11 patients underwent revision DCR during the follow-ups, and 7 patients were in the general group and 3 patients were in the local group. The overall success rate was 90%. Conclusion: External DCR surgery with both general and local anesthesia is a very effective technique for the treatment of nasolacrimal duct obstruction. In addition, local anesthesia may be brought to mind as an option considering less bleeding, shorter discharge time, and cost-effectivity and also to avoid perioperative and postoperative systemic complications for patients with high risks of general anesthesia.
Language	English
Publishing date	2022-02-18
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	3031466-5
ISSN	2587-0394 ; 2459-1777
ISSN (online)	2587-0394
ISSN	2459-1777
DOI	10.14744/bej.2021.95967
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Article: Evaluation of anatomical and functional outcomes in patients undergoing repair of traumatic canalicular laceration.

Aytoğan, Hasan / Karadeniz Uğurlu, Şeyda

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES

2017 Volume 23, Issue 1, Page(s) 66–71

Abstract: Background: The present study was designed to evaluate functional and anatomical success of traumatic canalicular laceration repair.: Methods: Consecutive patients who presented at Atatürk Training and Research Hospital Eye Clinic, İzmir Katip Çelebi ...

Abstract	Background: The present study was designed to evaluate functional and anatomical success of traumatic canalicular laceration repair. Methods: Consecutive patients who presented at Atatürk Training and Research Hospital Eye Clinic, İzmir Katip Çelebi University Faculty of Medicine and had canalicular laceration repair performed by the same surgeon between January 2009 and December 2014 were included in the study. Demographic data, length of time between injury and surgery, and cause of the trauma, surgical method employed, and duration of follow-up were recorded. Postoperative epiphora was evaluated using Munk score. Patency of lacrimal system was assessed with canalicular irrigation. Results: Thirty-five male and 6 female patients were included in the study. Mean age of 41 participants was 31.85±18.9 years (range: 1-79 years). Avulsive injury was observed in 66% (n=27), and direct (penetrating) injury in 34% (n=14). Distribution of injured canaliculi was as follows: left inferior canaliculus 63.4% (n=26), right inferior canaliculus 19.5% (n=8), right superior canaliculus 9.8% (n=4), and left superior canaliculus 7.3% (n=3). Thirty-four patients had monocanalicular tube implantation (mini-Monoka) and 10 patients had bicanalicular annular intubation using pigtail probe. Average follow-up time was 6±5.7 months. Munk score was Grade 0 in all patients. Canalicular irrigation indicated all canaliculi were patent. Conclusion: Recent microsurgical techniques result in successful repair of canalicular laceration.
MeSH term(s)	Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Eye Injuries/pathology ; Eye Injuries/surgery ; Female ; Humans ; Infant ; Lacrimal Apparatus/injuries ; Lacrimal Apparatus/pathology ; Lacrimal Apparatus/surgery ; Male ; Microsurgery ; Middle Aged ; Treatment Outcome ; Turkey ; Young Adult
Language	English
Publishing date	2017-01
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2253739-9
ISSN	1306-696X
ISSN	1306-696X
DOI	10.5505/tjtes.2016.65021
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Article ; Online: Specifying the Role of Masks in Reducing Viral Material on Environmental Surfaces of an Ophthalmology Examination Room-Reply.

Aytogan, Hasan / Ayintap, Emre / Yilmaz, Nisel Özkalay

JAMA ophthalmology

2021 Volume 139, Issue 3, Page(s) 366

MeSH term(s)	COVID-19 ; Humans ; Masks ; Ophthalmology ; SARS-CoV-2
Language	English
Publishing date	2021-01-27
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2701705-9
ISSN	2168-6173 ; 2168-6165
ISSN (online)	2168-6173
ISSN	2168-6165
DOI	10.1001/jamaophthalmol.2020.6568
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Article ; Online: Fluorescence of ocular surface in a Covid -19 patient after Favipiravir treatment: a case report.

Doran, Mehmet Ali / Aytogan, Hasan / Ayıntap, Emre

Virology journal

2021 Volume 18, Issue 1, Page(s) 146

Abstract: Background: Favipiravir is used in treatment of Covid-19 patients. We aimed to share of ocular surface fluorescence in a patient after Favipiravir treatment in this case report.: Case presentation: A 20-year-old male patient declared no known ... ...

Abstract	Background: Favipiravir is used in treatment of Covid-19 patients. We aimed to share of ocular surface fluorescence in a patient after Favipiravir treatment in this case report. Case presentation: A 20-year-old male patient declared no known systemic disease prior to Covid-19. He applied to us with blurry vision and blue light reflection after Covid-19 treatment with Favipiravir. We observed bilateral fluorescence on his eyes and fluorescence of his nails. Biomicroscopic examination was insignificant. Conclusion: We investigated the fluorescence of favipiravir tablets under ultraviolet light. Drug demonstrated fluorescence. We recorded the favipiravir fluorescence in-vitro. This appears to be a strong evidence in terms of the linkage between the fluorescence of the ocular surface and favipiravir.
MeSH term(s)	Adult ; Amides/administration & dosage ; Amides/adverse effects ; Amides/chemistry ; Antiviral Agents/administration & dosage ; Antiviral Agents/adverse effects ; Antiviral Agents/chemistry ; COVID-19/drug therapy ; COVID-19/virology ; Eye/chemistry ; Eye/virology ; Fluorescence ; Humans ; Male ; Pyrazines/administration & dosage ; Pyrazines/adverse effects ; Pyrazines/chemistry ; SARS-CoV-2/physiology
Chemical Substances	Amides ; Antiviral Agents ; Pyrazines ; favipiravir (EW5GL2X7E0)
Language	English
Publishing date	2021-07-13
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1743-422X
ISSN (online)	1743-422X
DOI	10.1186/s12985-021-01610-3
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Article ; Online: Detection of Coronavirus Disease 2019 Viral Material on Environmental Surfaces of an Ophthalmology Examination Room.

Aytogan, Hasan / Ayintap, Emre / Özkalay Yilmaz, Nisel

JAMA ophthalmology

2020 Volume 138, Issue 9, Page(s) 990–993

Abstract: Importance: The new coronavirus disease 2019 (COVID-19) pandemic poses a particular threat to health care professionals; however, there appear to be no objective data that demonstrate the risks of encountering individuals carrying the virus ... ...

Abstract	Importance: The new coronavirus disease 2019 (COVID-19) pandemic poses a particular threat to health care professionals; however, there appear to be no objective data that demonstrate the risks of encountering individuals carrying the virus asymptomatically in the case of maintained elective examinations. Objective: To investigate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the environmental surfaces of an ophthalmology examination room after visits by patients who were asymptomatic and had passed COVID-19 triage. Design, setting, and participants: This is a quality improvement study conducted 1 week after the first officially confirmed COVID-19 case in İzmir Tepecik Training and Research Hospital, İzmir, Turkey, on March 20, 2020. A triage system was used to determine the risk of COVID-19 from patients who were asymptomatic and presented for examination in an ophthalmology clinic. Real-time polymerase chain reaction testing was used to detect the presence of viral RNA material in samples from the biomicroscope stage, slitlamp breath shield, phoropter, tonometer, and door handles. The first group of samples was taken before the beginning of the examinations, and the second group of the samples was taken after the last patient had left the room. Main outcomes and measures: The main outcome was the presence of viral material on surfaces in 5 circular zones with a diameter of 1 m each around where the patients sat. Results: Thirty-one persons visited the room, of whom 22 underwent ophthalmic examination and 9 were companions. The mean (SD) examination time was 9 (4) minutes (range, 5-13 minutes). Seven samples were taken before examinations and 7 after examinations. Two samples that were taken after examinations were found to be positive for COVID-19, 1 from the slitlamp breath shield and 1 from the phoropter. Conclusions and relevance: This study showed the presence of COVID-19 viral material in a circle 1 m in diameter around where the patients sat. However, real-time polymerase chain reaction could only detect viral material, not the infectivity of these virus samples.
MeSH term(s)	Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/virology ; Environmental Microbiology ; Humans ; Ophthalmology ; Pandemics ; Pneumonia, Viral/virology ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2 ; Time Factors
Keywords	covid19
Language	English
Publishing date	2020-08-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2701705-9
ISSN	2168-6173 ; 2168-6165
ISSN (online)	2168-6173
ISSN	2168-6165
DOI	10.1001/jamaophthalmol.2020.3154
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