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  1. Article ; Online: Recognising rat-bite fever-a rare metastatic infection with Streptobacillus moniliformis.

    Hall, Clayton W / AlHammadi, Amena / Hasan, Mohammad Rubayet / Kapoor, Andrew K

    The Lancet. Infectious diseases

    2023  Volume 24, Issue 1, Page(s) e69

    MeSH term(s) Animals ; Rats ; Rat-Bite Fever/diagnosis ; Rat-Bite Fever/drug therapy ; Streptobacillus
    Language English
    Publishing date 2023-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00635-7
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    Zs.A 5743: Show issues Location:
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  2. Article: Evaluation of Immulex

    Suleiman, Mohammed / Elamin, Nazik / Nabor, Rhanty / Roberts, Jill / Tang, Patrick / Hasan, Mohammad Rubayet / Pérez-López, Andrés

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e22106

    Abstract: Rapid and early identification of : Importance: Invasive pneumococcal disease remains a major public health problem worldwide. Reducing the time to ... ...

    Abstract Rapid and early identification of
    Importance: Invasive pneumococcal disease remains a major public health problem worldwide. Reducing the time to identify
    Language English
    Publishing date 2023-11-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e22106
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  3. Article: Metabolomics in the Diagnosis and Prognosis of COVID-19.

    Hasan, Mohammad Rubayet / Suleiman, Mohammed / Pérez-López, Andrés

    Frontiers in genetics

    2021  Volume 12, Page(s) 721556

    Abstract: Coronavirus disease 2019 (COVID-19) pandemic triggered an unprecedented global effort in developing rapid and inexpensive diagnostic and prognostic tools. Since the genome of SARS-CoV-2 was uncovered, detection of viral RNA by RT-qPCR has played the most ...

    Abstract Coronavirus disease 2019 (COVID-19) pandemic triggered an unprecedented global effort in developing rapid and inexpensive diagnostic and prognostic tools. Since the genome of SARS-CoV-2 was uncovered, detection of viral RNA by RT-qPCR has played the most significant role in preventing the spread of the virus through early detection and tracing of suspected COVID-19 cases and through screening of at-risk population. However, a large number of alternative test methods based on SARS-CoV-2 RNA or proteins or host factors associated with SARS-CoV-2 infection have been developed and evaluated. The application of metabolomics in infectious disease diagnostics is an evolving area of science that was boosted by the urgency of COVID-19 pandemic. Metabolomics approaches that rely on the analysis of volatile organic compounds exhaled by COVID-19 patients hold promise for applications in a large-scale screening of population in point-of-care (POC) setting. On the other hand, successful application of mass-spectrometry to detect specific spectral signatures associated with COVID-19 in nasopharyngeal swab specimens may significantly save the cost and turnaround time of COVID-19 testing in the diagnostic microbiology and virology laboratories. Active research is also ongoing on the discovery of potential metabolomics-based prognostic markers for the disease that can be applied to serum or plasma specimens. Several metabolic pathways related to amino acid, lipid and energy metabolism were found to be affected by severe disease with COVID-19. In particular, tryptophan metabolism via the kynurenine pathway were persistently dysregulated in several independent studies, suggesting the roles of several metabolites of this pathway such as tryptophan, kynurenine and 3-hydroxykynurenine as potential prognostic markers of the disease. However, standardization of the test methods and large-scale clinical validation are necessary before these tests can be applied in a clinical setting. With rapidly expanding data on the metabolic profiles of COVID-19 patients with varying degrees of severity, it is likely that metabolomics will play an important role in near future in predicting the outcome of the disease with a greater degree of certainty.
    Language English
    Publishing date 2021-07-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2021.721556
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  4. Article: Effect of 2400 MHz mobile phone radiation exposure on the behavior and hippocampus morphology in Swiss mouse model.

    Hasan, Imam / Rubayet Jahan, Mir / Nabiul Islam, Md / Rafiqul Islam, Mohammad

    Saudi journal of biological sciences

    2021  Volume 29, Issue 1, Page(s) 102–110

    Abstract: Electromagnetic field exposure to the nervous system can cause neurological changes. The effects of extremely low-frequency electromagnetic fields, such as second-generation and third-generation radiation, have been studied in most studies. The current ... ...

    Abstract Electromagnetic field exposure to the nervous system can cause neurological changes. The effects of extremely low-frequency electromagnetic fields, such as second-generation and third-generation radiation, have been studied in most studies. The current study aimed to explore fourth-generation cellular phone radiation on hippocampal morphology and behavior in mice. Swiss albino male mice (n = 30) were randomly categorized into 3 groups; control, 40 min, and 60 min exposure to 2400 MHz radiofrequency electromagnetic radiation (RF-EMR) daily for 60 days. The control mice were housed in the same environments but were not exposed to anything. Anxiety-like behaviors were tested using the elevated plus-maze. For histological and stereological examination, the brain was dissected from the cranial cavity. On Cresyl violet stained brain slices, the number of pyramidal neurons in the cornu ammonis of the hippocampus were counted. In exposed mice compared to control mice, a significant increase in anxiety-like behavior has been observed. Histological observations have shown many black and dark blue cytoplasmic cells with shrunken morphology degenerative alterations in the neuronal hippocampus in the radiation exposed mice. In the RF-EMR mouse hippocampus, stereological analyses revealed a significant decrease in pyramidal and granule neurons compared to controls. Our findings suggest that 2400-MHz RF-EMR cell phone radiation affects the structural integrity of the hippocampus, which would lead to behavioral changes such as anxiety. However, it alerts us to the possible long-term detrimental effects of exposure to RF-EMR.
    Language English
    Publishing date 2021-08-25
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2021.08.063
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  5. Article ; Online: Variations in respiratory syncytial virus activity following the relaxation of COVID-19 restrictions in Qatar.

    Pérez-López, Andrés / Al Mana, Hassan / Iqbal, Muhammad / Suleiman, Mohammed / Hasan, Mohammad Rubayet / Tang, Patrick

    Journal of travel medicine

    2022  Volume 29, Issue 6

    MeSH term(s) COVID-19/prevention & control ; Humans ; Infant ; Qatar/epidemiology ; Respiratory Syncytial Virus, Human ; Seasons
    Language English
    Publishing date 2022-05-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taac065
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    Zs.A 4120: Show issues Location:
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  6. Article ; Online: Resurgence of influenza A infections in children after the relaxation of COVID-19-related social distancing measures and normalization of international travel in Qatar.

    Pérez-López, Andrés / Al Mana, Hassan / Iqbal, Muhammad / Suleiman, Mohammed / Hasan, Mohammad Rubayet / Tang, Patrick

    Journal of travel medicine

    2022  Volume 29, Issue 8

    MeSH term(s) Child ; Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; Physical Distancing ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Qatar/epidemiology ; SARS-CoV-2 ; Travel
    Language English
    Publishing date 2022-09-20
    Publishing country England
    Document type Letter
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taac107
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    Zs.A 4120: Show issues Location:
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  7. Article ; Online: Monitoring the effect of environmental conditions on safety of fresh produce sold in Qatar's wholesale market.

    Elnemr, I / Mushtaha, M / Sundararaju, Sathyavathi / Hasan, Mohammad Rubayet / Tsui, Kin-Ming / Goktepe, I

    International journal of environmental health research

    2021  Volume 32, Issue 9, Page(s) 1986–2004

    Abstract: Fresh produce imported by Qatar are mostly sold at the wholesale produce market (WPM) located in open-air and near major animal markets and slaughterhouses. This study was the first in Qatar to monitor the effect of environmental conditions on the ... ...

    Abstract Fresh produce imported by Qatar are mostly sold at the wholesale produce market (WPM) located in open-air and near major animal markets and slaughterhouses. This study was the first in Qatar to monitor the effect of environmental conditions on the microbial quality and safety of fresh produce sold at the WPM over 1 year. The monitoring involved the collection of 540 produce samples along with samples of air, soil, and surface swabs. Samples were analyzed for total aerobic bacteria (TAB); generic
    MeSH term(s) Animals ; Colony Count, Microbial ; Food Contamination/analysis ; Food Microbiology ; Qatar ; RNA, Ribosomal, 16S
    Chemical Substances RNA, Ribosomal, 16S
    Language English
    Publishing date 2021-06-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1104887-6
    ISSN 1369-1619 ; 0960-3123
    ISSN (online) 1369-1619
    ISSN 0960-3123
    DOI 10.1080/09603123.2021.1931050
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    Zs.A 3517: Show issues Location:
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  8. Article ; Online: First report of NDM-1-producing Pseudomonas aeruginosa in the Arabian Peninsula.

    Basahel, Ali / Shurab, Nada / Sundararaju, Sathyavathi / Hasan, Mohammad Rubayet / Tsui, Kin Ming / Suleiman, Mohammed / Imam, Omar / Tang, Patrick / Pérez-López, Andrés

    Journal of global antimicrobial resistance

    2021  Volume 29, Page(s) 553–554

    MeSH term(s) Humans ; Pseudomonas Infections ; Pseudomonas aeruginosa/genetics ; beta-Lactamases/genetics
    Chemical Substances beta-Lactamases (EC 3.5.2.6) ; beta-lactamase NDM-1 (EC 3.5.2.6)
    Language English
    Publishing date 2021-12-17
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7173
    ISSN (online) 2213-7173
    ISSN 2213-7173
    DOI 10.1016/j.jgar.2021.12.007
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  9. Article ; Online: A Novel Point Mutation in the N Gene of SARS-CoV-2 May Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR.

    Hasan, Mohammad Rubayet / Sundararaju, Sathyavathi / Manickam, Chidambaram / Mirza, Faheem / Al-Hail, Hamad / Lorenz, Stephan / Tang, Patrick

    Journal of clinical microbiology

    2021  Volume 59, Issue 4

    MeSH term(s) COVID-19 ; Humans ; Point Mutation ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Reverse Transcription ; SARS-CoV-2 ; Sensitivity and Specificity
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-03-19
    Publishing country United States
    Document type Letter
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.03278-20
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  10. Article ; Online: Draft Genome Sequence of an Extended-Spectrum β-Lactamase-Producing Klebsiella oxytoca Strain Bearing

    Tsui, Clement K M / Sundararaju, Sathyavathi / Al Mana, Hassan / Hasan, Mohammad Rubayet / Tang, Patrick / Perez-Lopez, Andres

    Microbiology resource announcements

    2020  Volume 9, Issue 23

    Abstract: Klebsiella ... ...

    Abstract Klebsiella oxytoca
    Language English
    Publishing date 2020-06-04
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/MRA.00429-20
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