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Article ; Online: The scenario of the studies on ragweed (Ambrosia Sp.) and related issues from its beginning to today: a useful tool for future goals in a one health approach.

Albertini, Roberto / Veronesi, Licia / Colucci, Maria Eugenia / Pasquarella, Cesira

2022 Volume 93, Issue 5, Page(s) e2022324

Abstract: Background and aim: Airborne ragweed pollen is one of the agents of respiratory allergies in our changing environment. The monitoring of pollen is essential to manage pollen allergy and to improve its forecasting methods. Moreover, the control and fight ...

Abstract	Background and aim: Airborne ragweed pollen is one of the agents of respiratory allergies in our changing environment. The monitoring of pollen is essential to manage pollen allergy and to improve its forecasting methods. Moreover, the control and fight against ragweed plants is important. Aim of this study is to understand the scenario of the studies on ragweed over time. Methods: We searched PubMed and Scopus for articles published until July 2022 reporting the words "ragweed". Articles written in all languages were included. Results: Scopus was the database with the highest number of published papers. Among the papers on ragweed, the papers citing the word "allergy" were 59.4% in PubMed and 37,6% in Scopus. The subject areas more addressed were medicine, immunology, genetics/molecular biology, but agricultural/biological sciences too and, interestingly, other subjects like social sciences, art, humanistic, etc.). Among the top 40 institutions supporting research, 8 were European, 4 Asian, 1 Russian and 21 were American, the other 6 were pharmaceutical companies. Conclusions: This study shows a picture of the ragweed studies and some related subjects over time. A gap between the number of biomedical and not biomedical issues was evident. There is a need for greater involvement of institutions into support of knowledge and fight ragweed. The results will provide a useful tool to identify future goals in a global approach of ragweed related issues.
MeSH term(s)	Humans ; Ambrosia ; Goals ; One Health ; Pollen ; Rhinitis, Allergic, Seasonal
Language	English
Publishing date	2022-10-26
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2114240-3
ISSN	2531-6745 ; 0392-4203
ISSN (online)	2531-6745
ISSN	0392-4203
DOI	10.23750/abm.v93i5.13771
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Article ; Online: Clinical efficacy of medical hydrology: an umbrella review.

Antonelli, Michele / Donelli, Davide / Veronesi, Licia / Vitale, Marco / Pasquarella, Cesira

International journal of biometeorology

2021 Volume 65, Issue 10, Page(s) 1597–1614

Abstract: The aim of this research was to summarize available scientific evidence on the efficacy of medical hydrology for the management of any health condition. The search was conducted on 26th March 2021, in the following databases: Medline (via PubMed), EMBASE, ...

Abstract	The aim of this research was to summarize available scientific evidence on the efficacy of medical hydrology for the management of any health condition. The search was conducted on 26th March 2021, in the following databases: Medline (via PubMed), EMBASE, Web of Science, Cochrane Library, and Google Scholar. All relevant literature reviews investigating the clinical efficacy of interventions characterized by the use of natural mineral waters and muds were included. The quality of studies was assessed with the "AMSTAR 2" tool. After article screening, 49 reviews were included in this work. Overall, retrieved scientific evidence suggests that spa therapy is beneficial for patients affected by some specific musculoskeletal conditions, with improvements potentially lasting up to 9 months. Moreover, balneotherapy can be an integrative support for the management of chronic venous insufficiency and some inflammatory skin diseases like psoriasis. The role of spa therapy in rehabilitation appears relevant as well. More limited, although interesting evidence exists for inhalation and hydropinic therapies. Globally, retrieved evidence suggests that, besides individual wellbeing, medical hydrology can be useful for public health. In particular, higher-quality studies seem to support the integrative use of spa-related interventions for conditions like osteoarthritis, fibromyalgia, low back pain of rheumatic origin, and chronic venous insufficiency. However, the body of evidence has some limitations and further clinical trials should be designed for each relevant application to consolidate and expand acquired knowledge.
MeSH term(s)	Balneology ; Fibromyalgia ; Humans ; Hydrology ; Mineral Waters ; Review Literature as Topic ; Systematic Reviews as Topic ; Treatment Outcome
Chemical Substances	Mineral Waters
Language	English
Publishing date	2021-04-17
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	280324-0
ISSN	1432-1254 ; 0020-7128
ISSN (online)	1432-1254
ISSN	0020-7128
DOI	10.1007/s00484-021-02133-w
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Article ; Online: An overview on the use of ultraviolet radiation to disinfect air and surfaces.

Albertini, Roberto / Colucci, Maria Eugenia / Coluccia, Alessia / Mohieldin Mahgoub Ibrahim, Mostafa / Zoni, Roberta / Veronesi, Licia / Affanni, Paola / Pasquarella, Cesira

Acta bio-medica : Atenei Parmensis

2023 Volume 94, Issue S3, Page(s) e2023165

Abstract: Background and aim Ultraviolet radiation (UV) is the portion of the electromagnetic spectrum of wavelengths between 200 and 400 nm divided into three bands called UVA, UVB and UVC. Due its well-described antimicrobial activity, UVC can represent a useful ...

Abstract	Background and aim Ultraviolet radiation (UV) is the portion of the electromagnetic spectrum of wavelengths between 200 and 400 nm divided into three bands called UVA, UVB and UVC. Due its well-described antimicrobial activity, UVC can represent a useful tool for disinfect surfaces, water, and air. The aim of this study was to illustrate the studies over time ultraviolet germicidal irradiation (UVGI) to disinfect air and surfaces. Methods Articles on Scopus published until April 14, 2023, were considered. Many issues involving UV were deepened crosschecking with e.g., "air", "surfaces", "disinfection", "bacteria", "fungi", "operating theatres". According to the case, the following variables were considered: years and related number of articles, sources of publications, subject areas, type of document published, type of journal, nationalities of the authors. Results Since 30's, 287 448 articles on UV have been published. Among UVGI, 22 159 articles covered bacteria issue, followed by fungi and viruses with about 12000 both. UVGI was addressed by 1941 and 931 articles for surfaces and air respectively. Of these, 122 were performed in operating theatres. Since 1987 works have been published on spacecraft and since 2000, on the use of UVGI robots for disinfect air and surfaces. Conclusions Our study shows the studies on UVGI and related issues. It also shows most recently perspectives about the applications e.g. during prolonged human-crewed missions on spacecrafts, to inactivate microorganisms in environments where the exchange of air is impossible.
MeSH term(s)	Humans ; Ultraviolet Rays ; Water
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2023-08-30
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	2114240-3
ISSN	2531-6745 ; 0392-4203
ISSN (online)	2531-6745
ISSN	0392-4203
DOI	10.23750/abm.v94iS3.14666
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Article ; Online: An overview of the studies on microbial air contamination in operating theatres and related issues over time: a useful tool for a multidisciplinary approach.

Albertini, Roberto / Coluccia, Alessia / Colucci, Maria Eugenia / Zoni, Roberta / Affanni, Paola / Veronesi, Licia / Pasquarella, Cesira

Acta bio-medica : Atenei Parmensis

2023 Volume 94, Issue S3, Page(s) e2023149

Abstract: Background and aim Surgical site infection (SSI) is a major complication following surgery associated with increased morbidity and mortality, as well as increased health and not health costs. A variety of factors affect airborne contamination in ... ...

Abstract	Background and aim Surgical site infection (SSI) is a major complication following surgery associated with increased morbidity and mortality, as well as increased health and not health costs. A variety of factors affect airborne contamination in operating theatres (OT). Following the Medical Research Council study showing a correlation between microbial air contamination and SSI incidence in prosthetic joint surgery ultraclean OTs have been recommended for this type of surgery, while OTs supplied by turbulent airflow plants are recommended for other types of surgery. The aim of this study was to illustrate the studies on this topic. Methods Scopus was considered for articles published until January 2023 on OTs and air contamination in article title or abstract or keywords. Many issues were deepened: "microbial", "bacterial", "fungi", "viruses", "surgical site/wound infection", "monitoring/sampling", "air changes", "behaviour", "door openings", "particles", turbulent flow", "unidirectional flow". Results Total papers published were 907 and 249 papers faced monitoring/sampling. A total of 313 papers investigated airborne bacterial contamination and 63 papers investigated fungal air contamination. There were 218 papers that have evaluated particle contamination in OTs. Many other issues were deepened. Conclusions This study shows a picture of the studies on biological air contamination in OTs and related issues over time. We think that the results of our study will provide a useful tool to increase awareness towards a better sharing of aims, approaches, and results, above all in the interest of the patients, but also of the health services of the different countries. (www.actabiomedica.it).
MeSH term(s)	Humans ; Surgical Wound Infection/prevention & control ; Air Microbiology ; Operating Rooms
Language	English
Publishing date	2023-08-30
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2114240-3
ISSN	2531-6745 ; 0392-4203
ISSN (online)	2531-6745
ISSN	0392-4203
DOI	10.23750/abm.v94iS3.14507
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Article ; Online: Air microbial sampling in operating theatres by active and passive methods: equation correlation from the GISIO-ISChIA study results and comparison with the EU GGMP recommendation, towards the definition of threshold values.

Pasquarella, Cesira Isabella Maria / Auxilia, Francesco / Barchitta, Martina / Cristina, Maria Luisa / D'Alessandro, Daniela / Mura, Ida / Nobile, Marta / Veronesi, Licia / Albertini, Roberto / Agodi, Antonella

Acta bio-medica : Atenei Parmensis

2023 Volume 94, Issue 1, Page(s) e2023017

Abstract: The aim of this study was to calculate the equation of correlation between the microbial air contamination values obtained by active sampling (colony-forming units per cubic metre, CFU/m3) and by passive sampling (Index of microbial air contamination, ... ...

Abstract	The aim of this study was to calculate the equation of correlation between the microbial air contamination values obtained by active sampling (colony-forming units per cubic metre, CFU/m3) and by passive sampling (Index of microbial air contamination, IMA), by using the data from the ISChIA study, and to compare the values obtained with the recommended limits defined by the EU Guidelines to Good Manufacturing Practice (EU GGMP), 2008, for clean areas used to manufacture sterile medicinal products. Air sampling was performed during 335 elective prosthesis procedures. Correlation between CFU/m3 and IMA values was evaluated using the Spearman test; p<0.05 was considered to indicate significance. This equation was used to calculate the IMA values corresponding to the CFU/m3 recommended threshold values by EU GGMP for the different Grades of microbial contamination. The following correlation equation was obtained: y = 1.86 + 0.12x, where "x" = cfu/m3 value and "y" = IMA value. The relationships between CFU/m3 and IMA values obtained from active and passive sampling during the ISChIA study showed to be in line to those suggested by the EU GGMP for pharmaceutical manufacturing for Grade C and D. This study shows that the EU GGMP relationship could be considered valid also for operating theatres. Both methods, active and passive samplings, can be used to evaluate microbial air quality and highlight critical situations; however, in particular during the activity, passive sampling estimating the risk posed by airborne microorganisms to the surgical wound, can be considered more relevant, and for its simplicity, economy and standardization, can be suggested for routine microbial monitoring.
MeSH term(s)	Humans ; Air Microbiology ; Operating Rooms ; Surgical Wound
Chemical Substances	geranylgeraniol monophosphate (68982-81-0)
Language	English
Publishing date	2023-02-13
Publishing country	Italy
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2114240-3
ISSN	2531-6745 ; 0392-4203
ISSN (online)	2531-6745
ISSN	0392-4203
DOI	10.23750/abm.v94i1.14012
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Article: Clinical efficacy of medical hydrology: an umbrella review

Antonelli, Michele / Donelli, Davide / Veronesi, Licia / Vitale, Marco / Pasquarella, Cesira

International journal of biometeorology. 2021 Oct., v. 65, no. 10

2021

Abstract	The aim of this research was to summarize available scientific evidence on the efficacy of medical hydrology for the management of any health condition. The search was conducted on 26th March 2021, in the following databases: Medline (via PubMed), EMBASE, Web of Science, Cochrane Library, and Google Scholar. All relevant literature reviews investigating the clinical efficacy of interventions characterized by the use of natural mineral waters and muds were included. The quality of studies was assessed with the “AMSTAR 2” tool. After article screening, 49 reviews were included in this work. Overall, retrieved scientific evidence suggests that spa therapy is beneficial for patients affected by some specific musculoskeletal conditions, with improvements potentially lasting up to 9 months. Moreover, balneotherapy can be an integrative support for the management of chronic venous insufficiency and some inflammatory skin diseases like psoriasis. The role of spa therapy in rehabilitation appears relevant as well. More limited, although interesting evidence exists for inhalation and hydropinic therapies. Globally, retrieved evidence suggests that, besides individual wellbeing, medical hydrology can be useful for public health. In particular, higher-quality studies seem to support the integrative use of spa-related interventions for conditions like osteoarthritis, fibromyalgia, low back pain of rheumatic origin, and chronic venous insufficiency. However, the body of evidence has some limitations and further clinical trials should be designed for each relevant application to consolidate and expand acquired knowledge.
Keywords	bioclimatology ; breathing ; hydrology ; musculoskeletal system ; osteoarthritis ; pain ; psoriasis ; public health ; therapeutics
Language	English
Dates of publication	2021-10
Size	p. 1597-1614.
Publishing place	Springer Berlin Heidelberg
Document type	Article
Note	Review
ZDB-ID	127361-9
ISSN	0067-8902 ; 0020-7128
ISSN	0067-8902 ; 0020-7128
DOI	10.1007/s00484-021-02133-w
Database	NAL-Catalogue (AGRICOLA)

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Article: La promozione della salute a venticinque anni dalla Carta di Ottawa.

Pasquarella, Cesira / Pasquarella, Maria Luisa

Igiene e sanita pubblica

2012 Volume 68, Issue 3, Page(s) 447–471

Abstract: Twenty-five years have passed since the Ottawa Charter for Health Promotion was signed at the First International Conference on Health Promotion, organized by the World Health Organization. This article traces the evolution of the definition of health, ... ...

Title translation	Health promotion 25 years after the Ottawa Charter.
Abstract	Twenty-five years have passed since the Ottawa Charter for Health Promotion was signed at the First International Conference on Health Promotion, organized by the World Health Organization. This article traces the evolution of the definition of health, the introduction of the "salutogenesis" approach to health, the evolution of educational processes in community health, and defines the concept of health promotion, describing its application needs.
MeSH term(s)	Global Health ; Health Education ; Health Policy ; Health Promotion/organization & administration ; Health Status ; Humans ; International Cooperation ; Italy ; Ontario ; Preventive Medicine/organization & administration ; Public Health ; Quality of Life ; Time Factors ; World Health Organization
Language	Italian
Publishing date	2012-05
Publishing country	Italy
Document type	English Abstract ; Journal Article
ISSN	0019-1639
ISSN	0019-1639
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Article: Air quality in the operating theatre: a perspective

Pasquarella, Cesira / Agodi, Antonella / Auxilia, Francesco / Lytsy, Birgitta / Mura, Ida / Parneix, Pierre / Popp, Walter / Brusaferro, Silvio

Aerobiologia. 2020 Mar., v. 36, no. 1

2020

Abstract: Operating theatres are among the hospital’s most risky environments as far as infections are concerned. Surgical site infection is a serious complication of surgery, associated with increased morbidity, mortality and costs. The ambient air of the ... ...

Abstract	Operating theatres are among the hospital’s most risky environments as far as infections are concerned. Surgical site infection is a serious complication of surgery, associated with increased morbidity, mortality and costs. The ambient air of the operating theatre represents an important vehicle of micro-organisms causing surgical site infection, in particular in clean operations. The aim of this paper is to give a brief historical excursus of the milestones of the prevention of airborne surgical site infections. The debated issue on the use of unidirectional airflow ventilation system is presented. Some national recommendations for threshold air microbial contamination values are reported, and the need for a European standard on air quality to provide a safe operating theatre environment for surgical patients is underlined.
Keywords	air ; air flow ; air quality ; hospitals ; microbial contamination ; microorganisms ; morbidity ; mortality ; patients ; surgery ; ventilation systems
Language	English
Dates of publication	2020-03
Size	p. 113-117.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	1499126-3
ISSN	1573-3025 ; 0393-5965
ISSN (online)	1573-3025
ISSN	0393-5965
DOI	10.1007/s10453-019-09584-0
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Response to Comments on Montagna et al. "Evaluation of Legionella Air Contamination in Healthcare Facilities by Different Sampling Methods: An Italian Multicenter Study" Int. J. Environ. Res. Public Health 2017, 14, 670.

Montagna, Maria Teresa / De Giglio, Osvalda / Agodi, Antonella / Pasquarella, Cesira

International journal of environmental research and public health

2017 Volume 14, Issue 8

Abstract: We would like to thank Collins andWalker for their comments and for acknowledging that this is an area requiring more research to improve our basic understanding of Legionella [1]. [ ... ]. ...

Abstract	We would like to thank Collins andWalker for their comments and for acknowledging that this is an area requiring more research to improve our basic understanding of Legionella [1]. [...].
MeSH term(s)	Italy ; Legionella ; Public Health
Language	English
Publishing date	2017-08-11
Publishing country	Switzerland
Document type	Journal Article ; Comment
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph14080906
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Article ; Online: Solar ultraviolet light collector for germicidal irradiation on the moon.

Lombini, Matteo / Schreiber, Laura / Albertini, Roberto / Alessi, Elisa Maria / Attinà, Primo / Bianco, Andrea / Cascone, Enrico / Colucci, Maria Eugenia / Cortecchia, Fausto / De Caprio, Vincenzo / Diolaiti, Emiliano / Fiorini, Mauro / Lessio, Luigi / Macchi, Alberto / Malaguti, Giuseppe / Mongelluzzo, Giuseppe / Pareschi, Giovanni / Pelizzo, Maria G / Pasquarella, Cesira

Scientific reports

2023 Volume 13, Issue 1, Page(s) 8326

Abstract: Prolonged human-crewed missions on the Moon are foreseen as a gateway for Mars and asteroid colonisation in the next decades. Health risks related to long-time permanence in space have been partially investigated. Hazards due to airborne biological ... ...

Abstract	Prolonged human-crewed missions on the Moon are foreseen as a gateway for Mars and asteroid colonisation in the next decades. Health risks related to long-time permanence in space have been partially investigated. Hazards due to airborne biological contaminants represent a relevant problem in space missions. A possible way to perform pathogens' inactivation is by employing the shortest wavelength range of Solar ultraviolet radiation, the so-called germicidal range. On Earth, it is totally absorbed by the atmosphere and does not reach the surface. In space, such Ultraviolet solar component is present and effective germicidal irradiation for airborne pathogens' inactivation can be achieved inside habitable outposts through a combination of highly reflective internal coating and optimised geometry of the air ducts. The Solar Ultraviolet Light Collector for Germicidal Irradiation on the Moon is a project whose aim is to collect Ultraviolet solar radiation and use it as a source to disinfect the re-circulating air of the human outposts. The most favourable positions where to place these collectors are over the peaks at the Moon's poles, which have the peculiarity of being exposed to solar radiation most of the time. On August 2022, NASA communicated to have identified 13 candidate landing regions near the lunar South Pole for Artemis missions. Another advantage of the Moon is its low inclination to the ecliptic, which maintains the Sun's apparent altitude inside a reduced angular range. For this reason, Ultraviolet solar radiation can be collected through a simplified Sun's tracking collector or even a static collector and used to disinfect the recycled air. Fluid-dynamic and optical simulations have been performed to support the proposed idea. The expected inactivation rates for some airborne pathogens, either common or found on the International Space Station, are reported and compared with the proposed device efficiency. The results show that it is possible to use Ultraviolet solar radiation directly for air disinfection inside the lunar outposts and deliver a healthy living environment to the astronauts.
Language	English
Publishing date	2023-05-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-35438-4
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