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  1. Article ; Online: Apples, oranges, and ectopic pregnancies.

    Meyer, Jessica A / Quinn, Gwendolyn P / Penfield, Christina A

    Fertility and sterility

    2023  Volume 119, Issue 5, Page(s) 813–814

    MeSH term(s) Female ; Humans ; Pregnancy, Ectopic/diagnosis
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2023.02.032
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    Zs.A 73: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Respiratory Distress Syndrome is Associated with Increased Morbidity and Mortality in Late Preterm Births.

    Berger, Dana S / Garg, Bharti / Penfield, Christina A / Caughey, Aaron B

    American journal of obstetrics & gynecology MFM

    2024  , Page(s) 101374

    Abstract: Background: Respiratory Distress Syndrome (RDS) is strongly associated with prematurity, including late preterm births. RDS has been shown to be associated with certain neonatal morbidities and mortality, but these associations are not well described ... ...

    Abstract Background: Respiratory Distress Syndrome (RDS) is strongly associated with prematurity, including late preterm births. RDS has been shown to be associated with certain neonatal morbidities and mortality, but these associations are not well described among late preterm births.
    Objective: We sought to determine the association between RDS and adverse neonatal outcomes among late preterm (34-36 weeks) born singleton neonates.
    Study design: This is a retrospective cohort study using California's linked vital statistics-patient discharge data (2008-2019). We included singleton, non-anomalous births with gestational age of 34-36 weeks. Outcomes of interest were interventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), retinopathy of prematurity (ROP), neonatal sepsis, length of hospital stay, neonatal death and infant death. Chi-square and multivariable Poisson regression analyses were used to examine the association of RDS with outcomes at each gestational age. Adjusted risk ratios (aRR) and 95% confidence intervals (CI) were estimated.
    Results: A total of 242,827 births were included, of which 11,312 (4.7%) had RDS. We found that among neonates with RDS, NEC was higher at 35 weeks (aRR= 3.97; 95% CI: 1.88, 8.41) and 36 weeks (aRR= 4.53; 95% CI: 1.45, 14.13). IVH, ROP, neonatal sepsis and length of hospital stay were significantly higher at 34-36 weeks' gestation in neonates with RDS. Neonatal death was significantly higher among neonates with RDS at 35 weeks (aRR=3.04; 95% CI: 1.58, 5.85) and 36 weeks (aRR=3.25; 95% CI: 1.59, 6.68). Infant death was also significantly higher at 35 weeks (aRR=2.27; 95% CI: 1.43, 3.61) and 36 weeks (aRR=2.60; 95% CI: 1.58, 4.28).
    Conclusion: We found that RDS was associated with IVH, ROP and sepsis at 34-36 weeks' gestation; while RDS was associated with neonatal death, infant death and NEC at 35 and 36 weeks. Clinicians should keep these outcomes in mind when making decisions about delivery timing and the potential benefits of antenatal steroids in pregnancies in the late preterm period as well as management of RDS in late preterm neonates.
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ISSN 2589-9333
    ISSN (online) 2589-9333
    DOI 10.1016/j.ajogmf.2024.101374
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  3. Article ; Online: Reproductive Health in Congenital Heart Disease: Preconception, Pregnancy, and Postpartum.

    Halpern, Dan G / Penfield, Christina A / Feinberg, Jodi L / Small, Adam J

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 5

    Abstract: The prevalence of congenital heart disease (CHD) in pregnancy is rising due to the improved survival of patients with CHD into childbearing age. The profound physiological changes that occur during pregnancy may worsen or unmask CHD, affecting both ... ...

    Abstract The prevalence of congenital heart disease (CHD) in pregnancy is rising due to the improved survival of patients with CHD into childbearing age. The profound physiological changes that occur during pregnancy may worsen or unmask CHD, affecting both mother and fetus. Successful management of CHD during pregnancy requires knowledge of both the physiological changes of pregnancy and the potential complications of congenital heart lesions. Care of the CHD patient should be based on a multidisciplinary team approach beginning with preconception counseling and continuing into conception, pregnancy, and postpartum periods. This review summarizes the published data, available guidelines and recommendations for the care of CHD during pregnancy.
    Language English
    Publishing date 2023-04-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10050186
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  4. Article ; Online: Decision-making for congenital anomalies diagnosed during pregnancy: a narrative review.

    Pecoriello, Jillian / Lilly, Anna- Grace / Jalili, Dona / Mendoza, Clarisa / Quinn, Gwendolyn P / Penfield, Christina A

    Journal of assisted reproduction and genetics

    2024  

    Abstract: Purpose: The purpose of this narrative review was to assess the limited literature on fetal anomalies diagnosed in the second trimester of pregnancy and parental decision-making and identify sources of information deemed as facilitators and barriers to ... ...

    Abstract Purpose: The purpose of this narrative review was to assess the limited literature on fetal anomalies diagnosed in the second trimester of pregnancy and parental decision-making and identify sources of information deemed as facilitators and barriers to medical decisions.
    Methods: This was a literature review of source material and information about fetal anomalies diagnosed in the second trimester of pregnancy, decision-making, decision tools or aids, and sources of information for anomalies. The search string used explored related peer-reviewed publications and systematic reviews between 2007 and 2024. We also reviewed references from publications meeting inclusion criteria. The search was conducted between June 2022 and February 2024. Exclusion criteria included conference abstracts, non-peer reviewed literature, and articles not available in English language. A total of 77 publications were identified by searching multiple databases using a predefined search string. The search encompassed full text articles from 2007 to 2024 and 11 full-text publications were ultimately included in the review. A list of 45 co-occurring keywords was generated from the included texts, with each keyword having a minimum of two co-occurrences.
    Results: Key themes identified included (1) the role of the clinician and need for development of professional knowledge and empathy surrounding discussion of fetal anomalies with patients; (2) information gathering, with individuals reporting use of multiple strategies to obtain information; while the majority found information satisfying, they preferred more details on diagnosis, long-term outcomes of the fetus/child and management of the pregnancy or termination process; and (3) decision-making, the path and process of how individuals made decisions about the pregnancy including quality of life, future fertility, and seeking other people's experiences.
    Conclusion: Many factors contribute to an individual's decision-making after a diagnosis of a fetal anomalies diagnosed in the second trimester of pregnancy, ranging from personal beliefs and goals to shared experiences of others and access to care. Understanding how sources of information may be deemed both as facilitators and barriers to different individuals during the decision-making process is important for healthcare providers in order to understand how to most effectively support patients. There is a dearth of information on training healthcare professionals to provide support to patients facing these decisions.
    Language English
    Publishing date 2024-04-17
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1112577-9
    ISSN 1573-7330 ; 1058-0468
    ISSN (online) 1573-7330
    ISSN 1058-0468
    DOI 10.1007/s10815-024-03112-x
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    Zs.A 1985: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: A Pregnant Adolescent with COVID-19 and Multisystem Inflammatory Syndrome in Children.

    Trostle, Megan E / Grossman, Tracy B / Penfield, Christina A / Phoon, Colin K L / Raabe, Vanessa N / Sloane, Mark F / Roman, Ashley S

    AJP reports

    2024  Volume 14, Issue 1, Page(s) e66–e68

    Abstract: Multisystem inflammatory syndrome in children (MIS-C), a new condition related to coronavirus disease 2019 (COVID-19) in the pediatric population, was recognized by physicians in the United Kingdom in April 2020. Given those up to the age of 21 years can ...

    Abstract Multisystem inflammatory syndrome in children (MIS-C), a new condition related to coronavirus disease 2019 (COVID-19) in the pediatric population, was recognized by physicians in the United Kingdom in April 2020. Given those up to the age of 21 years can be affected, pregnant adolescents and young adults are susceptible. However, there is scant information on how MIS-C may affect pregnancy and whether the presentation differs in the pregnant population. We report a case of a pregnant adolescent with COVID-19 and MIS-C with a favorable outcome. This case highlights the considerations in managing a critically ill pregnant patient with a novel illness and the importance of a multidisciplinary team in coordinating care.
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2628074-7
    ISSN 2157-7005 ; 2157-6998
    ISSN (online) 2157-7005
    ISSN 2157-6998
    DOI 10.1055/s-0044-1779032
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    Zs.A 6934: Show issues Location:
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  6. Article ; Online: Adjustment of the spontaneous abortion rate following COVID-19 vaccination.

    Trostle, Megan E / Penfield, Christina A / Roman, Ashley S

    American journal of obstetrics & gynecology MFM

    2021  Volume 4, Issue 1, Page(s) 100511

    MeSH term(s) Abortion, Spontaneous ; COVID-19 ; COVID-19 Vaccines ; Female ; Humans ; Pregnancy ; SARS-CoV-2 ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-10-14
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2589-9333
    ISSN (online) 2589-9333
    DOI 10.1016/j.ajogmf.2021.100511
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  7. Article ; Online: Comparing outcomes of fetal growth restriction defined by estimated fetal weight versus isolated abdominal circumference.

    Griffin, Myah M / Mehta-Lee, Shilpi S / Penfield, Christina A / Roman, Ashley S

    Archives of gynecology and obstetrics

    2023  

    Abstract: Purpose: The objective of this study was to compare maternal and neonatal outcomes when the diagnosis of FGR was based on isolated abdominal circumference < 10th percentile for gestational age (GA) (iAC group) versus overall estimated fetal weight < ... ...

    Abstract Purpose: The objective of this study was to compare maternal and neonatal outcomes when the diagnosis of FGR was based on isolated abdominal circumference < 10th percentile for gestational age (GA) (iAC group) versus overall estimated fetal weight < 10th percentile (EFW group).
    Methods: This was a retrospective cohort study of singleton gestations who underwent growth ultrasounds and delivered at a single health system from 1/1/19-9/4/20. The study group was comprised of patients with AC < 10th percentile and EFW ≥ than the 10th percentile (iAC group). The control group included patients with overall EFW < 10th percentile (EFW group). Outcomes evaluated included GA at delivery, mode of delivery, fetal and neonatal outcomes. Data was analyzed using Mann Whitney U, X
    Results: 635 women met the inclusion criteria, 259 women in the iAC group and 376 women in the EFW group. The iAC group was noted to have a later GA at diagnosis and delivery. iAC was associated with lower rates of preterm birth (PTB), NICU admission, SGA at delivery and umbilical artery cord gas < 7.0.
    Conclusion: Using iAC as a definition of FGR increased the number of FGR cases by 1.69-fold over EFW criteria alone. However, obstetrical and neonatal outcomes for the iAC group appear to be significantly better than those in the EFW group, with low rates of PTB, NICU admission, and umbilical artery cord gas < 7.0.
    Language English
    Publishing date 2023-10-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-023-07241-z
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    Um I Zs.55: Show issues Location:
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  8. Article ; Online: Association between Peripartum Mean Arterial Pressure and Postpartum Readmission for Preeclampsia with Severe Features.

    Lin, Bing-Xue / Smith, Maria / Sutter, Megan / Penfield, Christina A / Proudfit, Christine

    American journal of perinatology

    2023  

    Abstract: Objective:  This study aimed to evaluate the relationship between peripartum mean arterial pressure (MAP) and postpartum readmission for preeclampsia with severe features.: Study design:  This is a retrospective case-control study comparing adult ... ...

    Abstract Objective:  This study aimed to evaluate the relationship between peripartum mean arterial pressure (MAP) and postpartum readmission for preeclampsia with severe features.
    Study design:  This is a retrospective case-control study comparing adult parturients readmitted for preeclampsia with severe features to matched nonreadmitted controls. Our primary objective was to evaluate the association between MAP at three time points during the index hospitalization (admission, 24-hour postpartum, and discharge) and readmission risk. We also evaluated readmission risk by age, race, body mass index, and comorbidities. Our secondary aim was to establish MAP thresholds to identify the population at highest risk of readmission. Multivariate logistic regression and chi-squared tests were used to determine the adjusted odds of readmission based on MAP. Receiver operating characteristic analyses were performed to evaluate risk of readmission relative to MAP; optimal MAP thresholds were established to identify those at highest risk of readmission. Pairwise comparisons were made between subgroups after stratifying for history of hypertension, with a focus on readmitted patients with new-onset postpartum preeclampsia.
    Results:  A total of 348 subjects met inclusion criteria, including 174 controls and 174 cases. We found that elevated MAP at both admission (adjusted odds ratio [OR]: 1.37 per 10 mm Hg,
    Conclusion:  Admission and 24-hour postpartum MAP correlate with risk of postpartum readmission for preeclampsia with severe features. Evaluating MAP at these time points may be useful for identifying women at higher risk for postpartum readmission. These women may otherwise be missed based on standard clinical approaches and may benefit from heightened surveillance.
    Key points: · Existing literature focuses on management of antenatal hypertensive disorders of pregnancy.. · Elevated peripartum MAP is associated with increased odds of readmission for preeclampsia.. · Peripartum MAP may predict readmission risk for de novo postpartum preeclampsia..
    Language English
    Publishing date 2023-06-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0043-1770705
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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Intrauterine vertical transmissibility of SARS-CoV-2: the evidence is evolving.

    Penfield, Christina A / Lighter, Jennifer / Roman, Ashley S

    American journal of obstetrics & gynecology MFM

    2020  Volume 2, Issue 4, Page(s) 100227

    MeSH term(s) COVID-19 ; Extraembryonic Membranes ; Female ; Humans ; Placenta ; Pregnancy ; Pregnancy Complications, Infectious ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-11
    Publishing country Switzerland
    Document type Letter ; Comment
    ISSN 2589-9333
    ISSN (online) 2589-9333
    DOI 10.1016/j.ajogmf.2020.100227
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  10. Article ; Online: COVID-19 transmissibility during labor and vaginal delivery.

    Hawks, Rebecca J Mahn / Ades, Veronica / Roman, Ashley S / Penfield, Christina A / Goddard, Brian

    American journal of obstetrics & gynecology MFM

    2022  Volume 5, Issue 1, Page(s) 100770

    MeSH term(s) Pregnancy ; Female ; Humans ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/prevention & control ; Delivery, Obstetric ; Trial of Labor ; Labor, Obstetric
    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Letter
    ISSN 2589-9333
    ISSN (online) 2589-9333
    DOI 10.1016/j.ajogmf.2022.100770
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