Article ; Online: Investigating the place of sodium-glucose cotransporter-2 inhibitors and dual sodium-glucose cotransporter-1 and dual sodium-glucose cotransporter-2 inhibitors in heart failure therapy: a systematic review of the literature.
2024 Volume 29, Issue 2, Page(s) 549–558
Abstract: Sodium-glucose cotransporter-2 inhibitors have been shown to have significant metabolic, renal, and atherosclerotic cardiovascular disease benefits. Recent randomized controlled trials have extended these benefits to patients with heart failure. In fact, ...
Abstract | Sodium-glucose cotransporter-2 inhibitors have been shown to have significant metabolic, renal, and atherosclerotic cardiovascular disease benefits. Recent randomized controlled trials have extended these benefits to patients with heart failure. In fact, the robust findings from these studies in patients with any type of heart failure have led to the incorporation of this drug class in currently updated evidence-based guidelines for this condition. However, given the novelty in utilizing these agents in heart failure, there is uncertainty regarding place in therapy and sequencing in treatment. As such, this review aims to summarize existing literature to guide practitioners regarding the use of these agents in the management of heart failure. |
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MeSH term(s) | Humans ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Diabetes Mellitus, Type 2/drug therapy ; Heart Failure/drug therapy ; Heart Failure/metabolism ; Diuretics/therapeutic use ; Sodium/therapeutic use ; Glucose |
Chemical Substances | Sodium-Glucose Transporter 2 Inhibitors ; Diuretics ; Sodium (9NEZ333N27) ; Glucose (IY9XDZ35W2) |
Language | English |
Publishing date | 2024-02-01 |
Publishing country | United States |
Document type | Systematic Review ; Journal Article ; Review |
ZDB-ID | 1336499-6 |
ISSN | 1573-7322 ; 1382-4147 |
ISSN (online) | 1573-7322 |
ISSN | 1382-4147 |
DOI | 10.1007/s10741-024-10388-9 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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