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  1. Article ; Online: Investigating the place of sodium-glucose cotransporter-2 inhibitors and dual sodium-glucose cotransporter-1 and dual sodium-glucose cotransporter-2 inhibitors in heart failure therapy: a systematic review of the literature.

    McKenzie, Taylor / Hale, Genevieve M / Miner, Amelia / Colón Colón, Jean / Evins, Garrett / Wade, Jasmine

    Heart failure reviews

    2024  Volume 29, Issue 2, Page(s) 549–558

    Abstract: Sodium-glucose cotransporter-2 inhibitors have been shown to have significant metabolic, renal, and atherosclerotic cardiovascular disease benefits. Recent randomized controlled trials have extended these benefits to patients with heart failure. In fact, ...

    Abstract Sodium-glucose cotransporter-2 inhibitors have been shown to have significant metabolic, renal, and atherosclerotic cardiovascular disease benefits. Recent randomized controlled trials have extended these benefits to patients with heart failure. In fact, the robust findings from these studies in patients with any type of heart failure have led to the incorporation of this drug class in currently updated evidence-based guidelines for this condition. However, given the novelty in utilizing these agents in heart failure, there is uncertainty regarding place in therapy and sequencing in treatment. As such, this review aims to summarize existing literature to guide practitioners regarding the use of these agents in the management of heart failure.
    MeSH term(s) Humans ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Diabetes Mellitus, Type 2/drug therapy ; Heart Failure/drug therapy ; Heart Failure/metabolism ; Diuretics/therapeutic use ; Sodium/therapeutic use ; Glucose
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors ; Diuretics ; Sodium (9NEZ333N27) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1336499-6
    ISSN 1573-7322 ; 1382-4147
    ISSN (online) 1573-7322
    ISSN 1382-4147
    DOI 10.1007/s10741-024-10388-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Machine Learning Identification of Organic Compounds Using Visible Light.

    Bikku, Thulasi / Fritz, Rubén A / Colón, Yamil J / Herrera, Felipe

    The journal of physical chemistry. A

    2023  Volume 127, Issue 10, Page(s) 2407–2414

    Abstract: Identifying chemical compounds is essential in several areas of science and engineering. Laser-based techniques are promising for autonomous compound detection because the optical response of materials encodes enough electronic and vibrational ... ...

    Abstract Identifying chemical compounds is essential in several areas of science and engineering. Laser-based techniques are promising for autonomous compound detection because the optical response of materials encodes enough electronic and vibrational information for remote chemical identification. This has been exploited using the fingerprint region of infrared absorption spectra, which involves a dense set of absorption peaks that are unique to individual molecules, thus facilitating chemical identification. However, optical identification using visible light has not been realized. Using decades of experimental refractive index data in the scientific literature of pure organic compounds and polymers over a broad range of frequencies from the ultraviolet to the far-infrared, we develop a machine learning classifier that can accurately identify organic species based on a single-wavelength dispersive measurement in the visible spectral region, away from absorption resonances. The optical classifier proposed here could be applied to autonomous material identification protocols and applications.
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.2c07955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Naval Postgraduate School COVID-19 Pandemic Response Procedures

    Colón, A.J.

    2020  

    Keywords covid19
    Publisher Monterey, California. Naval Postgraduate School
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Multipoint characterization of the emission of odour, volatile organic compounds and greenhouse gases from a full-scale membrane-based municipal WWTP.

    González, Daniel / Colón, Joan / Sánchez, Antoni / Gabriel, David

    Journal of environmental management

    2022  Volume 313, Page(s) 115002

    Abstract: Different environmental and social concerns can arise due to the generation of gaseous emissions during the treatment of urban wastewater. However, there is not an extensive knowledge about which are the main potential odour and greenhouse gas (GHG) ... ...

    Abstract Different environmental and social concerns can arise due to the generation of gaseous emissions during the treatment of urban wastewater. However, there is not an extensive knowledge about which are the main potential odour and greenhouse gas (GHG) emission sources in a wastewater treatment plant (WWTP) and their variability. In this study, a multipoint characterization of the gaseous emissions generated in a full-scale municipal WWTP located in Barcelona was conducted, aiming at identifying the main odour and GHG emission sources. The WWTP under study treats an average inlet flow of 33,000 m
    MeSH term(s) Gases/analysis ; Greenhouse Gases ; Odorants/analysis ; Volatile Organic Compounds/analysis ; Waste Water/analysis ; Water Purification
    Chemical Substances Gases ; Greenhouse Gases ; Volatile Organic Compounds ; Waste Water
    Language English
    Publishing date 2022-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2022.115002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Engineering entangled photon pairs with metal-organic frameworks.

    Fritz, Rubén A / Colón, Yamil J / Herrera, Felipe

    Chemical science

    2021  Volume 12, Issue 10, Page(s) 3475–3482

    Abstract: The discovery and design of new materials with competitive optical frequency conversion efficiencies can accelerate the development of scalable photonic quantum technologies. Metal-organic framework (MOF) crystals without inversion symmetry have shown ... ...

    Abstract The discovery and design of new materials with competitive optical frequency conversion efficiencies can accelerate the development of scalable photonic quantum technologies. Metal-organic framework (MOF) crystals without inversion symmetry have shown potential for these applications, given their nonlinear optical properties and the combinatorial number of possibilities for MOF self-assembly. In order to accelerate the discovery of MOF materials for quantum optical technologies, scalable computational assessment tools are needed. We develop a multi-scale methodology to study the wavefunction of entangled photon pairs generated by selected non-centrosymmetric MOF crystals
    Language English
    Publishing date 2021-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d0sc05572g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: In Search of the Holy Grail of Artificial Hearts: Are We There Yet?

    Volod, Oksana / Colon, Modesto J / Arabía, Francisco A

    Seminars in thrombosis and hemostasis

    2023  Volume 50, Issue 1, Page(s) 104–114

    Abstract: The total artificial heart (TAH) has a long and rich history, being the product of decades of innovation, hard work, and dedication. This review examines the history of the TAH, a device that has revolutionized the treatment of end-stage biventricular ... ...

    Abstract The total artificial heart (TAH) has a long and rich history, being the product of decades of innovation, hard work, and dedication. This review examines the history of the TAH, a device that has revolutionized the treatment of end-stage biventricular heart failure. It reviews the development of the device from early concepts to the current state-of-the-art device, the SynCardia TAH, which has been implanted in over 2,000 patients worldwide. The article also discusses the challenges and successes experienced by researchers, clinicians, and patients throughout the development of TAH devices. Our focus will also be on discussing the hemostatic alterations in patients implanted with TAH and anticoagulation strategies to decrease associated thromboembolic risks. The article concludes with a look at other novel TAH devices and the future of TAH as an increasingly viable treatment for end-stage heart failure.
    MeSH term(s) Humans ; Heart Failure/therapy ; Heart Transplantation ; Heart, Artificial
    Language English
    Publishing date 2023-08-21
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 196901-8
    ISSN 1098-9064 ; 0094-6176
    ISSN (online) 1098-9064
    ISSN 0094-6176
    DOI 10.1055/s-0043-1772456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Experiences from the implementation of physical therapy via telehealth for individuals with Parkinson disease during the COVID-19 pandemic.

    Colón-Semenza, C / Zajac, J A / Schwartz, A / Darbandsari, P / Ellis, T D

    Disability and rehabilitation

    2023  Volume 46, Issue 8, Page(s) 1593–1601

    Abstract: Purpose: To (1) determine the characteristics and participation rate of adults with Parkinson disease (PD) in physical therapy (PT) delivered via telehealth, (2) identify the outcome measures and interventions implemented, (3) determine the safety of ... ...

    Abstract Purpose: To (1) determine the characteristics and participation rate of adults with Parkinson disease (PD) in physical therapy (PT) delivered via telehealth, (2) identify the outcome measures and interventions implemented, (3) determine the safety of and (4) patient and therapist satisfaction with PT via telehealth in a clinic specializing in the care of people with PD during the coronavirus pandemic.
    Materials & methods: A retrospective analysis of PT services via telehealth was conducted. Participating patients completed a satisfaction survey. Physical therapists (PTs) who delivered this care were interviewed. Three coders conducted thematic analysis of interviews. Descriptive statistics described the participation rate, demographics, outcome measures, interventions, and safety.
    Results: There was a 71.4% participation rate. Participants (
    Conclusions: Patients reported satisfaction with PT via telehealth during the pandemic. A hybrid model may support optimal delivery of PT.IMPLICATIONS FOR REHABILITATIONPhysical therapy via telehealth for patients with Parkinson disease was acceptable to patients and physical therapists in our study.Physical therapy via telehealth was safe for people with Parkinson disease in our study, although availability and benefits may not be reaching all populations equitably.Both physical therapists and patients endorse a hybrid model of care (a combination of in-person and remote assessment and treatment) to profit from the strengths of in-person and virtual formats while minimizing barriers to access.
    MeSH term(s) Male ; Humans ; Aged ; Pandemics ; Parkinson Disease/therapy ; Retrospective Studies ; COVID-19/epidemiology ; Telemedicine ; Physical Therapy Modalities
    Language English
    Publishing date 2023-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1104775-6
    ISSN 1464-5165 ; 0963-8288
    ISSN (online) 1464-5165
    ISSN 0963-8288
    DOI 10.1080/09638288.2023.2202418
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Author Correction: Projecting the future incidence and burden of dengue in Southeast Asia.

    Colón-González, Felipe J / Gibb, Rory / Khan, Kamran / Watts, Alexander / Lowe, Rachel / Brady, Oliver J

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 6518

    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-42378-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Projecting the future incidence and burden of dengue in Southeast Asia.

    Colón-González, Felipe J / Gibb, Rory / Khan, Kamran / Watts, Alexander / Lowe, Rachel / Brady, Oliver J

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 5439

    Abstract: The recent global expansion of dengue has been facilitated by changes in urbanisation, mobility, and climate. In this work, we project future changes in dengue incidence and case burden to 2099 under the latest climate change scenarios. We fit a ... ...

    Abstract The recent global expansion of dengue has been facilitated by changes in urbanisation, mobility, and climate. In this work, we project future changes in dengue incidence and case burden to 2099 under the latest climate change scenarios. We fit a statistical model to province-level monthly dengue case counts from eight countries across Southeast Asia, one of the worst affected regions. We project that dengue incidence will peak this century before declining to lower levels with large variations between and within countries. Our findings reveal that northern Thailand and Cambodia will show the biggest decreases and equatorial areas will show the biggest increases. The impact of climate change will be counterbalanced by income growth, with population growth having the biggest influence on increasing burden. These findings can be used for formulating mitigation and adaptation interventions to reduce the immediate growing impact of dengue virus in the region.
    MeSH term(s) Humans ; Incidence ; Cambodia/epidemiology ; Thailand/epidemiology ; Acclimatization ; Dengue/epidemiology
    Language English
    Publishing date 2023-09-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-41017-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Disparities in Postoperative Communication Patterns Among Spanish-speaking Pediatric Patients with Hydrocephalus.

    Ruiz Colón, Gabriela D / Pizzitola, Rebecca J / Grant, Gerald A / Prolo, Laura M

    The Journal of pediatrics

    2023  Volume 263, Page(s) 113678

    Abstract: Objective: To determine if differences exist in postoperative communication patterns or healthcare use among English-speaking patients (ESPs) and Spanish-speaking patients (SSPs) with childhood hydrocephalus.: Study design: A single-institution, ... ...

    Abstract Objective: To determine if differences exist in postoperative communication patterns or healthcare use among English-speaking patients (ESPs) and Spanish-speaking patients (SSPs) with childhood hydrocephalus.
    Study design: A single-institution, retrospective cohort study was conducted. Through simple random sampling, 50 ESPs and 50 SSPs (<18 years old) who underwent a ventriculoperitoneal shunt or endoscopic third ventriculostomy were identified. Demographics, communication with clinic (eg, number of calls or messages postoperatively), and healthcare use were collected. Multiple linear regressions assessed the significance of predictors on communication frequency and use.
    Results: SSPs were more likely to have a comorbidity and ventriculoperitoneal shunt than ESPs. SSPs had longer median postoperative length of stay (P < .01) and 30-day readmission rate (P < .01) than ESPs. Only 18% of SSPs communicated with clinic; 11 total calls or messages were from SSPs vs 57 from ESPs (P < .01). The most common reason for outreach among both cohorts was a new symptom. ESP outreach most frequently resulted in reassurance or medical course changes on an outpatient basis (30% ESPs vs 0% SSPs; P = .04), whereas SSP outreach most frequently resulted in guidance to present to the emergency department (3% ESPs vs 36% SSPs; P < .01). Language remained a significant predictor for number of calls or messages, even after adjusting for comorbidity, operation type, and insurance (P < .01).
    Conclusions: Despite having more complex disease, only 18% of SSPs communicated with the neurosurgical team postoperatively and were more frequently sent to the emergency department for management. Future research will explore communication barriers and preferences to ensure postoperative care is timely and patient centered.
    MeSH term(s) Child ; Humans ; Adolescent ; Retrospective Studies ; Communication ; Hydrocephalus/surgery ; Hydrocephalus/etiology ; Language ; Ventriculostomy/methods ; Ventriculoperitoneal Shunt/methods ; Postoperative Complications/etiology
    Language English
    Publishing date 2023-08-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2023.113678
    Database MEDical Literature Analysis and Retrieval System OnLINE

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