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  1. Article ; Online: PELATIHAN MIGRASI DATA REKAM MEDIS MANUAL KE ELEKTRONIK

    Kori Puspita Ningsih / Endang Purwanti / Imaniar Sevtiyani / Sugeng Santoso / Muhammad Rifqi Ma'arif

    LINK, Vol 18, Iss 1, Pp 43-

    2022  Volume 48

    Abstract: Proses migrasi rekam medis manual (kertas) ke elektronik, yaitu serangkaian proses dimulai dari ... kegiatan migrasi data rekam medis manual ke elektronik dan demonstrasi cara melakukan alih media kepada ...

    Abstract Proses migrasi rekam medis manual (kertas) ke elektronik, yaitu serangkaian proses dimulai dari pengenalan rekam medis elektronik berikut manfaatnya, menyediakan semua yang diperlukan untuk penerapan sistem dan pelatihan penggunaan rekam medis elektronik oleh pengguna, diperlukan untuk mendukung penerapan RME. RSUD Wates sedang mengembangkan Rekam medis Elektronik (RME) dan rencana akan mengimplementasikan RME pada tahun 2022. Tujuan dari kegiatan PKM ini adalah memberikan penyuluhan langkah-langkah kegiatan migrasi data rekam medis manual ke elektronik dan demonstrasi cara melakukan alih media kepada instalasi rekam medis, koordinator filing dan staff rekam medis RSUD Wates. Metode PKM menggunakan Pendidikan masyarakat melakui kegiatan penyuluhan dan demonstrasi cara melakukan alih media menggunakan mesin scanner. Kegiatan PKM berjalan dengan lancar. Setelah dilaksanakan kegiatan PKM, RSUD Wates berencana melakukan proses migrasi data rekam medis manual menjadi elektronik secara bertahap, sesuai kunjungan pasien. Pada akhir sesi tim PKM menyerahkan hibah printer scanner untuk mendukung kegiatan alih media rekam medis.
    Keywords rekam medis ; migrasi data ; rme ; digitalisasi ; alih media ; Nursing ; RT1-120 ; Medicine (General) ; R5-920
    Language Indonesian
    Publishing date 2022-05-01T00:00:00Z
    Publisher UPPM Poltekkes Kemenkes Semarang
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1

    Bai, Ying / Zuo, Jiacheng / Fang, Xin / Ma, Rufeng / Tian, Tian / Mo, Fangfang / Mu, Qianqian / Zhang, Yi / Yu, Na / Bao, Xueli / Zhang, Dongwei / Gao, Sihua / Zhao, Dandan

    Oxidative medicine and cellular longevity

    2021  Volume 2021, Page(s) 5566053

    Abstract: The Jiang Tang Xiao Ke (JTXK) granule is a classic Chinese herbal formula that has been put ...

    Abstract The Jiang Tang Xiao Ke (JTXK) granule is a classic Chinese herbal formula that has been put into clinical use in the treatment of type 2 diabetes mellitus for decades. However, whether its ability to ameliorate skeletal muscle insulin resistance (IR) is through modulation of the AMPK/SIRT1/PGC-1
    MeSH term(s) AMP-Activated Protein Kinases/drug effects ; Animals ; Diabetes Mellitus, Experimental/drug therapy ; Diet, High-Fat/adverse effects ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Insulin Resistance/immunology ; Male ; Mice ; Muscle, Skeletal/drug effects ; Signal Transduction
    Chemical Substances Drugs, Chinese Herbal ; jiang tang xiao ke ; AMP-Activated Protein Kinases (EC 2.7.11.31)
    Language English
    Publishing date 2021-07-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2455981-7
    ISSN 1942-0994 ; 1942-0994
    ISSN (online) 1942-0994
    ISSN 1942-0994
    DOI 10.1155/2021/5566053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Guiding significance of "disease-syndrome-symptom" mode in FU Qing-zhu's Obstetrics and Gynecology (FU Qing-zhu Nyu Ke) for dealing with ovulation disorder infertility caused by hyperprolactinemia].

    Liu, Xiao-Qian / Ma, Kun / Zhang, Xiao-Yu / Yin, Yun-Dong

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2022  Volume 47, Issue 6, Page(s) 1694–1699

    Abstract: ... Obstetrics and Gynecology(FU Qing-zhu Nyu Ke) for dealing with ovulation disorder infertility caused ... by hyperprolactinemia(HPRL). FU Qing-zhu's Obstetrics and Gynecology(FU Qing-zhu Nyu Ke) concentrates on the disease ... zhu's Obstetrics and Gynecology(FU Qing-zhu Nyu Ke) sheds enlightenment on the diagnosis and treatment ...

    Abstract This paper discussed the guiding significance of "disease-syndrome-symptom" mode in FU Qing-zhu's Obstetrics and Gynecology(FU Qing-zhu Nyu Ke) for dealing with ovulation disorder infertility caused by hyperprolactinemia(HPRL). FU Qing-zhu's Obstetrics and Gynecology(FU Qing-zhu Nyu Ke) concentrates on the disease entities, main symptoms, pathogenesis, and syndrome differentiation, based on which the prescriptions are prescribed. This reflects the "disease-syndrome-symptom" mode, with the core lying in the "combination of disease with syndrome". The contained Discussion on Menstruation Regulation(Tiao Jing Pian) and Discussion on Getting Pregnant(Zhong Zi Pian) have important reference significance for later doctors in the diagnosis and treatment of inferti-lity, and many prescriptions are still in use due to good effects. It is believed in traditional Chinese medicine(TCM) that HPRL results from kidney deficiency and liver depression, among which kidney deficiency is the main cause. Liver depression accelerates the onset of HPRL, so the kidney-tonifying and liver-soothing herbs were mainly selected. The "disease-syndrome-symptom" mode in FU Qing-zhu's Obstetrics and Gynecology(FU Qing-zhu Nyu Ke) sheds enlightenment on the diagnosis and treatment of ovulation infertility caused by HPRL, in that it is not confined to disease entity and syndrome type. The integration of "disease-syndrome-symptom" highlights the main complaint of patients and emphasizes the main pathogenesis, thus giving full play to the overall advantage of syndrome differentiation. For multiple diseases in FU Qing-zhu's Obstetrics and Gynecology(FU Qing-zhu Nyu Ke) such as infertility due to liver depression, infertility due to obesity, delayed menstruation, and irregular menstruation, although the typical lactation symptom of HPRL is not mentioned, the medication can still be determined according to the chief complaint, syndrome type, and symptoms and signs, making up for the defects of excessive reliance on serum biochemical indicators in modern Chinese medicine. We should learn its diagnosis and treatment thoughts of paying attention to liver, spleen, kidney, and heart, holism, and strengthening body resistance to eliminate pathogenic factors.
    MeSH term(s) Female ; Gynecology ; Humans ; Hyperprolactinemia/complications ; Hyperprolactinemia/drug therapy ; Infertility ; Obstetrics ; Ovulation ; Pregnancy
    Language Chinese
    Publishing date 2022-03-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20211208.502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Zhong yi er ke xue

    Ma, Rong

    2015  

    Author's details zhu bian Ma Rong, Xu Hua
    MeSH term(s) Pediatrics ; Professional Competence ; Medicine, Chinese Traditional
    Language Chinese
    Size 12, 336 pages :, illustrations
    Edition Di 1 ban.
    Document type Book
    ISBN 9787117203548 ; 7117203544
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Article: Jiang Tang Xiao Ke Granule, a Classic Chinese Herbal Formula, Improves the Effect of Metformin on Lipid and Glucose Metabolism in Diabetic Mice.

    Zhang, Yi / An, Hong / Pan, Si-Yuan / Zhao, Dan-Dan / Zuo, Jia-Cheng / Li, Xiao-Ke / Gao, Ya / Mu, Qian-Qian / Yu, Na / Ma, Yue / Mo, Fang-Fang / Gao, Si-Hua

    Evidence-based complementary and alternative medicine : eCAM

    2016  Volume 2016, Page(s) 1592731

    Abstract: ... combined with Jiang Tang Xiao Ke (JTXK) granule derived from the "Di Huang Tang" were evaluated in mice ...

    Abstract In the present study, the hypoglycemic, hypolipidemic, and antioxidative effects of metformin (MET) combined with Jiang Tang Xiao Ke (JTXK) granule derived from the "Di Huang Tang" were evaluated in mice with type 2 diabetes mellitus (DM) induced by high-fat diet/streptozotocin. DM mice were orally treated with MET (0.19 g/kg) either alone or combined with different doses (1.75, 3.5, or 7 g/kg) of JTXK for 4 weeks. Results showed that the serum and hepatic glucose, lipids, and oxidative stress levels were elevated in DM mice, when compared with the normal mice. MET treatment decreased FBG and serum glucagon levels of DM mice. Combination treatment with MET and JTXK 3.5 g/kg increased the hypoglycemia and insulin sensitivity at 4 weeks when compared with the DM mice treated with MET alone. However, neither MET nor MET/JTXK treatment could completely reverse the hyperglycemia in DM mice. JTXK enhanced the serum triglyceride (TG) and hepatic lipid-lowering effect of MET in a dose-dependent manner in DM mice. JTXK 1.75 and 3.5 g/kg improved the hepatoprotective effect of MET in DM mice. Synergistic effect of combination treatment with MET and JTXK on antioxidant stress was also found in DM mice compared with MET alone.
    Language English
    Publishing date 2016-06-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2016/1592731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Xiao Ke Qing improves glycometabolism and ameliorates insulin resistance by regulating the PI3K/Akt pathway in KKAy mice.

    Li, Xiaoqing / Li, Xinxin / Wang, Genbei / Xu, Yan / Wang, Yuanyuan / Hao, Ruijia / Ma, Xiaohui

    Frontiers of medicine

    2018  Volume 12, Issue 6, Page(s) 688–696

    Abstract: Xiao Ke Qing (XKQ) granule has been clinically used to treat type 2 diabetes mellitus (T2DM) for 10 ...

    Abstract Xiao Ke Qing (XKQ) granule has been clinically used to treat type 2 diabetes mellitus (T2DM) for 10 years in Chinese traditional medication. However, its mechanisms against hyperglycemia remain poorly understood. This study aims to investigate XKQ mechanisms on diabetes and diabetic liver disease by using the KKAy mice model. Our results indicate that XKQ can significantly reduce food and water intake. XKQ treatment also remarkably decreases both the fasting blood glucose and blood glucose in the oral glucose tolerance test. Additionally, XKQ can significantly decrease the serum alanine aminotransferase level and liver index and can alleviate the fat degeneration in liver tissues. Moreover, XKQ can ameliorate insulin resistance and upregulate the expression of IRS-1, PI3K (p85), p-Akt, and GLUT4 in the skeletal muscle of KKAy mice. XKQ is an effective drug for T2DM by ameliorating insulin resistance and regulating the PI3K/Akt signaling pathway in the skeletal muscle.
    MeSH term(s) Animals ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Female ; Glucose Tolerance Test ; Glucose Transporter Type 4/metabolism ; Hypoglycemic Agents/pharmacology ; Insulin/blood ; Insulin Resistance ; Liver/drug effects ; Liver/pathology ; Mice ; Mice, Inbred C57BL ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects
    Chemical Substances Blood Glucose ; Drugs, Chinese Herbal ; Glucose Transporter Type 4 ; Hypoglycemic Agents ; Insulin ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2018-11-13
    Publishing country China
    Document type Journal Article
    ZDB-ID 2617113-2
    ISSN 2095-0225 ; 2095-0217
    ISSN (online) 2095-0225
    ISSN 2095-0217
    DOI 10.1007/s11684-018-0662-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Zhong yi fu chan ke ci dian

    Ma, Dazheng

    2015  

    Author's details Ma Dazheng bian zhu
    MeSH term(s) Obstetrics ; Genital Diseases, Female ; Medicine, Chinese Traditional ; Drugs, Chinese Herbal
    Language Chinese
    Size 82, 862 pages :, portraits
    Edition Di 1 ban.
    Document type Book
    ISBN 9787117218337 ; 7117218339
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Book: Zhongguo pi fu ke xue shi

    Ma, Zhenyou

    2015  

    Author's details Ma Zhenyou, Zhang Jianzhong, Zheng Huailin zhu bian
    MeSH term(s) Dermatology/history ; Sexually Transmitted Diseases/history ; Leprosy/history
    Keywords China
    Language Chinese
    Size 6, 614 p. :, ill., port.
    Edition Di 1 ban.
    Publisher Beijing ke xue ji shu chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787530469200 ; 7530469207
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article: Antidiabetic and antioxidative effect of jiang tang xiao ke granule in high-fat diet and low-dose streptozotocin induced diabetic rats.

    Zhao, Dan-Dan / Yu, Na / Li, Xiao-Ke / Fang, Xin / Mu, Qian-Qian / Qin, Pei-Jie / Ma, Yue / Mo, Fang-Fang / Zhang, Dong-Wei / Gao, Si-Hua

    Evidence-based complementary and alternative medicine : eCAM

    2014  Volume 2014, Page(s) 475192

    Abstract: ... in the world. The purpose of this study was to investigate the effect of Jiang Tang Xiao Ke (JTXK) granule ...

    Abstract Diabetes mellitus (DM), a kind of metabolic disease, is increasing over the last four decades in the world. The purpose of this study was to investigate the effect of Jiang Tang Xiao Ke (JTXK) granule, a naturally occurring ingredient from Chinese herbal medicines, on serum glucose, lipids, and oxidative stress in DM rats induced by high-fat diet and streptozotocin. JTXK granule 9 g/kg (based on crude herb equivalent) and pioglitazone 1.5 mg/kg (as a positive control for comparison) were orally administrated to DM rats for 4 weeks. Results showed that administration of JTXK granule reduced serum glucose, total cholesterol, triglyceride, and low density lipoprotein levels (by 12%, 33%, 57%, and 44%, resp.) but increased high-density lipoprotein level by 69%, compared with the drug-untreated DM rats. Serum malondialdehyde and nitric oxide levels were lowered (by 34% and 52%, resp.) associated with the elevation in serum superoxide dismutase levels (by 60%) after JTXK granule treatment. In addition, JTXK granule suppressed serum alanine aminotransferase activity (up to 50%) and alleviated pathological changes of pancreas and liver tissues in DM rats. The beneficial changes of pioglitazone on biomarkers were also found in DM rats. These findings suggested that JTXK granule may be an alternative medicine for the management of DM.
    Language English
    Publishing date 2014-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2014/475192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Metabolic profiling of hypoxia/reoxygenation injury in H9c2 cells reveals the accumulation of phytosphingosine and the vital role of Dan-Shen in Xin-Ke-Shu.

    Sun, Lili / Jia, Hongmei / Ma, Liyan / Yu, Meng / Yang, Yong / Liu, Yang / Zhang, Hongwu / Zou, Zhongmei

    Phytomedicine : international journal of phytotherapy and phytopharmacology

    2018  Volume 49, Page(s) 83–94

    Abstract: Background: Xin-Ke-Shu (XKS), a patent medicine consisting of five commonly used traditional ...

    Abstract Background: Xin-Ke-Shu (XKS), a patent medicine consisting of five commonly used traditional Chinese herbs, is used for the treatment of coronary heart diseases. A previous study showed that XKS has protective effects for ameliorating myocardial ischemia/reperfusion (I/R) injury.
    Purpose: This study was aimed to deeply understand the mechanisms and compatible principle of XKS against hypoxia/reoxygenation (H/R) injury and the contribution of each single herb to the efficacy of XKS.
    Methods: An H/R model in H9c2 cardiomyocytes was applied to mimic I/R injury observed in vivo. The cell viability, the levels of LDH, MDA, SOD, and apoptosis were determined to evaluate the cardioprotection of XKS and its subtracted formula (knocked out one herb) in H/R injury. Cell metabolomics, combined with western blot analysis, was performed to uncover the inert molecular mechanism of XKS against H/R injury.
    Results: Significant protective effects of XKS against oxidative stress and apoptosis induced by H/R injury were found in the pharmacodynamic evaluation. Moreover, the metabolic profile deviation of the H/R group from the control group was mainly ascribed to thirteen metabolites involved in four aberrant pathways, in which sphingolipid metabolism was revealed as the most relevant pathway involved in H/R injury (impact > 0.1). Notably, the accumulation of phytosphingosine (VIP = 5.84) was considered the most likely characteristic in H/R injury, which is well known to promote the opening of the mitochondrial permeability transition pore (mPTP) and activate cell apoptosis. Furthermore, XKS ameliorated all the abnormalities of the metabolic network in response to H/R injury. In agreement with this, a western blot analysis showed that XKS markedly regulated the over-expression of CaMK II and cleaved caspase-3. However, the subtracted formula showed no significant difference in comparison with the XKS group on protecting H/R injury except for QDS (subtracted Dan-Shen from XKS).
    Conclusion: The roots of Salvia miltiorrhiza Bge. (Dan-Shen) play an important role in the regulation of Ca
    MeSH term(s) Animals ; Apoptosis/drug effects ; Cell Hypoxia ; Cell Survival/drug effects ; Drugs, Chinese Herbal/pharmacology ; Metabolomics ; Mitochondrial Membrane Transport Proteins ; Myocardial Reperfusion Injury ; Myocytes, Cardiac/drug effects ; Oxidative Stress/drug effects ; Rats ; Salvia miltiorrhiza ; Sphingosine/analogs & derivatives ; Sphingosine/pharmacology
    Chemical Substances Drugs, Chinese Herbal ; Mitochondrial Membrane Transport Proteins ; mitochondrial permeability transition pore ; dan-shen root extract (79483-68-4) ; phytosphingosine (GIN46U9Q2Q) ; Sphingosine (NGZ37HRE42)
    Language English
    Publishing date 2018-06-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1205240-1
    ISSN 1618-095X ; 0944-7113
    ISSN (online) 1618-095X
    ISSN 0944-7113
    DOI 10.1016/j.phymed.2018.06.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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