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  1. Article: A population in perpetual motion: Highly dynamic roosting behavior of a tropical island endemic bat.

    Aguillon, Samantha / Le Minter, Gildas / Lebarbenchon, Camille / Hoarau, Axel O G / Toty, Céline / Joffrin, Léa / Ramanantsalama, Riana V / Augros, Stéphane / Tortosa, Pablo / Mavingui, Patrick / Dietrich, Muriel

    Ecology and evolution

    2023  Volume 13, Issue 2, Page(s) e9814

    Abstract: Although island endemic bats are a source of considerable conservation concerns, their biology remains poorly known. Here, we studied the phenology and roosting behavior of a tropical island endemic species: the Reunion free-tailed bat ( ...

    Abstract Although island endemic bats are a source of considerable conservation concerns, their biology remains poorly known. Here, we studied the phenology and roosting behavior of a tropical island endemic species: the Reunion free-tailed bat (
    Language English
    Publishing date 2023-02-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.9814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Development and characterization of 20 polymorphic microsatellite markers for the white-bellied pangolin Phataginus tricuspis (Mammalia, Pholidota)

    Aguillon, Samantha / Din Dipita, Alain / Lecompte, Emilie / Missoup, Alain Didier / Tindo, Maurice / Gaubert, Philippe

    Molecular biology reports. 2020 June, v. 47, no. 6

    2020  

    Abstract: Pangolins, or scaly anteaters, have recently been flagshiped as one of the most illegally traded mammals, and as a corollary, as potential intermediate hosts at the origin of the COVID-19 pandemic. In order to improve the traceability of their trade, we ... ...

    Abstract Pangolins, or scaly anteaters, have recently been flagshiped as one of the most illegally traded mammals, and as a corollary, as potential intermediate hosts at the origin of the COVID-19 pandemic. In order to improve the traceability of their trade, we developed 20 polymorphic microsatellite loci for the white-bellied pangolin (Phataginus tricuspis), the species most frequently found on African bushmeat markets. We genotyped 24 white-bellied pangolins from the Douala market, Cameroon, originating from the Ebo forest c. 75 km north-east of Douala. The number of alleles per locus ranged from 4 to 12 (mean = 6.95), and mean observed and expected heterozygosities were 0.592 (0.208–0.875) and 0.671 (0.469–0.836), respectively. Genetic diversity was higher than that cross-estimated from microsatellite loci developed for other species of pangolins. Two loci deviated from Hardy–Weinberg equilibrium and two loci showed linkage disequilibrium. Genetic variance (PCoA) was increased with the addition of 13 pangolins of unknown origin, possibly suggesting that the Douala market is fed from differentiated source populations of white-bellied pangolins. Each of the 37 individuals had a unique multilocus genotype. The unbiased probability of identity (uPI) and the probability of identity among siblings (PIsibs) were both very low (uPI = 8.443 e−21; PIsibs = 1.011 e−07). Only five microsatellite loci were needed to reach the conservative value of PIsibs < 0.01, overall indicating a powerful discriminating power of our combined loci. These 20 newly developed microsatellite loci might prove useful in tracing the local-to-global trade of the white-bellied pangolin, and will hopefully contribute to the DNA-assisted implementation of future conservation strategies at reasonable costs.
    Keywords COVID-19 infection ; Manis ; bushmeat ; forests ; genetic variance ; genetic variation ; linkage disequilibrium ; loci ; markets ; microsatellite repeats ; molecular biology ; probability ; traceability ; trade ; Cameroon
    Language English
    Dates of publication 2020-06
    Size p. 4827-4833.
    Publishing place Springer Netherlands
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-020-05511-6
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Development and characterization of 20 polymorphic microsatellite markers for the white-bellied pangolin Phataginus tricuspis (Mammalia, Pholidota).

    Aguillon, Samantha / Din Dipita, Alain / Lecompte, Emilie / Missoup, Alain Didier / Tindo, Maurice / Gaubert, Philippe

    Molecular biology reports

    2020  Volume 47, Issue 6, Page(s) 4827–4833

    Abstract: Pangolins, or scaly anteaters, have recently been flagshiped as one of the most illegally traded mammals, and as a corollary, as potential intermediate hosts at the origin of the COVID-19 pandemic. In order to improve the traceability of their trade, we ... ...

    Abstract Pangolins, or scaly anteaters, have recently been flagshiped as one of the most illegally traded mammals, and as a corollary, as potential intermediate hosts at the origin of the COVID-19 pandemic. In order to improve the traceability of their trade, we developed 20 polymorphic microsatellite loci for the white-bellied pangolin (Phataginus tricuspis), the species most frequently found on African bushmeat markets. We genotyped 24 white-bellied pangolins from the Douala market, Cameroon, originating from the Ebo forest c. 75 km north-east of Douala. The number of alleles per locus ranged from 4 to 12 (mean = 6.95), and mean observed and expected heterozygosities were 0.592 (0.208-0.875) and 0.671 (0.469-0.836), respectively. Genetic diversity was higher than that cross-estimated from microsatellite loci developed for other species of pangolins. Two loci deviated from Hardy-Weinberg equilibrium and two loci showed linkage disequilibrium. Genetic variance (PCoA) was increased with the addition of 13 pangolins of unknown origin, possibly suggesting that the Douala market is fed from differentiated source populations of white-bellied pangolins. Each of the 37 individuals had a unique multilocus genotype. The unbiased probability of identity (uPI) and the probability of identity among siblings (PIsibs) were both very low (uPI = 8.443 e-21; PIsibs = 1.011 e-07). Only five microsatellite loci were needed to reach the conservative value of PIsibs < 0.01, overall indicating a powerful discriminating power of our combined loci. These 20 newly developed microsatellite loci might prove useful in tracing the local-to-global trade of the white-bellied pangolin, and will hopefully contribute to the DNA-assisted implementation of future conservation strategies at reasonable costs.
    MeSH term(s) Alleles ; Animals ; Betacoronavirus/pathogenicity ; COVID-19 ; Cameroon/epidemiology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Disease Reservoirs/virology ; Eutheria/genetics ; Eutheria/virology ; Female ; Genetic Loci ; Genetic Markers ; Genotype ; Humans ; Linkage Disequilibrium ; Male ; Microsatellite Repeats ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Zoonoses/epidemiology ; Zoonoses/prevention & control ; Zoonoses/transmission ; Zoonoses/virology
    Chemical Substances Genetic Markers
    Keywords covid19
    Language English
    Publishing date 2020-05-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-020-05511-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A population in perpetual motion

    Samantha Aguillon / Gildas Le Minter / Camille Lebarbenchon / Axel O. G. Hoarau / Céline Toty / Léa Joffrin / Riana V. Ramanantsalama / Stéphane Augros / Pablo Tortosa / Patrick Mavingui / Muriel Dietrich

    Ecology and Evolution, Vol 13, Iss 2, Pp n/a-n/a (2023)

    Highly dynamic roosting behavior of a tropical island endemic bat

    2023  

    Abstract: Abstract Although island endemic bats are a source of considerable conservation concerns, their biology remains poorly known. Here, we studied the phenology and roosting behavior of a tropical island endemic species: the Reunion free‐tailed bat ( ... ...

    Abstract Abstract Although island endemic bats are a source of considerable conservation concerns, their biology remains poorly known. Here, we studied the phenology and roosting behavior of a tropical island endemic species: the Reunion free‐tailed bat (Mormopterus francoismoutoui). This widespread and abundant species occupies various natural and anthropogenic environments such as caves and buildings. We set up fine‐scale monitoring of 19 roosts over 27 months in Reunion Island and analyzed roost size and composition, sexual and age‐associated segregation of individuals, as well as the reproductive phenology and body condition of individuals. Based on extensive data collected from 6721 individuals, we revealed a highly dynamic roosting behavior, with marked seasonal sex‐ratio variation, linked to distinct patterns of sexual aggregation among roosts. Despite the widespread presence of pregnant females all over the island, parturition was localized in a few roosts, and flying juveniles dispersed rapidly toward all studied roosts. Our data also suggested a 7‐month delay between mating and pregnancy, highlighting a likely long interruption of the reproductive cycle in this tropical bat. Altogether, our results suggest a complex social organization in the Reunion free‐tailed bat, with important sex‐specific seasonal and spatial movements, including the possibility of altitudinal migration. Bat tracking and genetic studies would provide additional insights into the behavioral strategies that shape the biology of this enigmatic bat species. The fine‐scale spatiotemporal data revealed by our study will serve to the delineation of effective conservation plans, especially in the context of growing urbanization and agriculture expansion in Reunion Island.
    Keywords Chiroptera ; Molossidae ; reproductive seasonality ; Reunion Island ; sexual segregation ; tropical island bat ; Ecology ; QH540-549.5
    Subject code 910 ; 590
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Development and characterization of 20 polymorphic microsatellite markers for the white-bellied pangolin Phataginus tricuspis (Mammalia, Pholidota)

    Aguillon, Samantha / Din Dipita, Alain / Lecompte, Emilie / Missoup, Alain Didier / Tindo, Maurice / Gaubert, Philippe

    Mol Biol Rep

    Abstract: Pangolins, or scaly anteaters, have recently been flagshiped as one of the most illegally traded mammals, and as a corollary, as potential intermediate hosts at the origin of the COVID-19 pandemic. In order to improve the traceability of their trade, we ... ...

    Abstract Pangolins, or scaly anteaters, have recently been flagshiped as one of the most illegally traded mammals, and as a corollary, as potential intermediate hosts at the origin of the COVID-19 pandemic. In order to improve the traceability of their trade, we developed 20 polymorphic microsatellite loci for the white-bellied pangolin (Phataginus tricuspis), the species most frequently found on African bushmeat markets. We genotyped 24 white-bellied pangolins from the Douala market, Cameroon, originating from the Ebo forest c. 75 km north-east of Douala. The number of alleles per locus ranged from 4 to 12 (mean = 6.95), and mean observed and expected heterozygosities were 0.592 (0.208-0.875) and 0.671 (0.469-0.836), respectively. Genetic diversity was higher than that cross-estimated from microsatellite loci developed for other species of pangolins. Two loci deviated from Hardy-Weinberg equilibrium and two loci showed linkage disequilibrium. Genetic variance (PCoA) was increased with the addition of 13 pangolins of unknown origin, possibly suggesting that the Douala market is fed from differentiated source populations of white-bellied pangolins. Each of the 37 individuals had a unique multilocus genotype. The unbiased probability of identity (uPI) and the probability of identity among siblings (PIsibs) were both very low (uPI = 8.443 e-21; PIsibs = 1.011 e-07). Only five microsatellite loci were needed to reach the conservative value of PIsibs < 0.01, overall indicating a powerful discriminating power of our combined loci. These 20 newly developed microsatellite loci might prove useful in tracing the local-to-global trade of the white-bellied pangolin, and will hopefully contribute to the DNA-assisted implementation of future conservation strategies at reasonable costs.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #277073
    Database COVID19

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  6. Article ; Online: Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study.

    Sanchez, Justin S / Hanseeuw, Bernard J / Lopera, Francisco / Sperling, Reisa A / Baena, Ana / Bocanegra, Yamile / Aguillon, David / Guzmán-Vélez, Edmarie / Pardilla-Delgado, Enmanuelle / Ramirez-Gomez, Liliana / Vila-Castelar, Clara / Martinez, Jairo E / Fox-Fuller, Joshua T / Ramos, Claudia / Ochoa-Escudero, Martin / Alvarez, Sergio / Jacobs, Heidi I L / Schultz, Aaron P / Gatchel, Jennifer R /
    Becker, J Alex / Katz, Samantha R / Mayblyum, Danielle V / Price, Julie C / Reiman, Eric M / Johnson, Keith A / Quiroz, Yakeel T

    Alzheimer's research & therapy

    2021  Volume 13, Issue 1, Page(s) 27

    Abstract: Background: Neuroimaging studies of autosomal dominant Alzheimer's disease (ADAD) enable characterization of the trajectories of cerebral amyloid-β (Aβ) and tau accumulation in the decades prior to clinical symptom onset. Longitudinal rates of regional ... ...

    Abstract Background: Neuroimaging studies of autosomal dominant Alzheimer's disease (ADAD) enable characterization of the trajectories of cerebral amyloid-β (Aβ) and tau accumulation in the decades prior to clinical symptom onset. Longitudinal rates of regional tau accumulation measured with positron emission tomography (PET) and their relationship with other biomarker and cognitive changes remain to be fully characterized in ADAD.
    Methods: Fourteen ADAD mutation carriers (Presenilin-1 E280A) and 15 age-matched non-carriers from the Colombian kindred underwent 2-3 sessions of Aβ (11C-Pittsburgh compound B) and tau (18F-flortaucipir) PET, structural magnetic resonance imaging, and neuropsychological evaluation over a 2-4-year follow-up period. Annualized rates of change for imaging and cognitive variables were compared between carriers and non-carriers, and relationships among baseline measurements and rates of change were assessed within carriers.
    Results: Longitudinal measurements were consistent with a sequence of ADAD-related changes beginning with Aβ accumulation (16 years prior to expected symptom onset, EYO), followed by entorhinal cortex (EC) tau (9 EYO), neocortical tau (6 EYO), hippocampal atrophy (6 EYO), and cognitive decline (4 EYO). Rates of tau accumulation among carriers were most rapid in parietal neocortex (~ 9%/year). EC tau PET signal at baseline was a significant predictor of subsequent neocortical tau accumulation and cognitive decline within carriers.
    Conclusions: Our results are consistent with the sequence of biological changes in ADAD implied by cross-sectional studies and highlight the importance of EC tau as an early biomarker and a potential link between Aβ burden and neocortical tau accumulation in ADAD.
    MeSH term(s) Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/genetics ; Amyloid beta-Peptides ; Biomarkers ; Boston ; Colombia ; Cross-Sectional Studies ; Humans ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; tau Proteins/genetics
    Chemical Substances Amyloid beta-Peptides ; Biomarkers ; tau Proteins
    Language English
    Publishing date 2021-01-15
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2506521-X
    ISSN 1758-9193 ; 1758-9193
    ISSN (online) 1758-9193
    ISSN 1758-9193
    DOI 10.1186/s13195-020-00765-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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