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  1. Article ; Online: Childhood Circumstances and Mental Health in Old Age

    Huoyun Zhu / Mengting Liao

    International Journal of Environmental Research and Public Health, Vol 18, Iss 6420, p

    A Life Course Survey in China

    2021  Volume 6420

    Abstract: Current evidence and research of the life course approach on the association between life experiences and health in old age are fragmentary. This paper empirically examines the “long arm” effect of the childhood circumstances on mental health in later ... ...

    Abstract Current evidence and research of the life course approach on the association between life experiences and health in old age are fragmentary. This paper empirically examines the “long arm” effect of the childhood circumstances on mental health in later life using a large longitudinal dataset (CHARLS) conducted in 2014 and 2015. We operationalize the childhood circumstances as family economic conditions, community environment, and peer network to include the meaningful content and understand their interaction. The SEM results indicate that effects of those factors contributing to older people’s mental health are unequal and vary among age groups and genders. Of those, peer network in childhood determines to a large extent the mental health through the whole life course, while economic conditions and community environment are weakly associated with mental health. Furthermore, we find a distinct interaction mechanism linking those variables. The peer network completely mediates the effect of the community environment on the mental health of older adults and has a partial mediating effect on the economic conditions. Those findings suggest that social policies aimed at promoting older people’s mental health in the context of the active ageing and health ageing strategy should go beyond the old age stage and target social conditions early in childhood.
    Keywords population ageing ; childhood circumstances ; mental health ; life course ; active ageing ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Childhood Circumstances and Mental Health in Old Age: A Life Course Survey in China.

    Zhu, Huoyun / Liao, Mengting

    International journal of environmental research and public health

    2021  Volume 18, Issue 12

    Abstract: Current evidence and research of the life course approach on the association between life experiences and health in old age are fragmentary. This paper empirically examines the "long arm" effect of the childhood circumstances on mental health in later ... ...

    Abstract Current evidence and research of the life course approach on the association between life experiences and health in old age are fragmentary. This paper empirically examines the "long arm" effect of the childhood circumstances on mental health in later life using a large longitudinal dataset (CHARLS) conducted in 2014 and 2015. We operationalize the childhood circumstances as family economic conditions, community environment, and peer network to include the meaningful content and understand their interaction. The SEM results indicate that effects of those factors contributing to older people's mental health are unequal and vary among age groups and genders. Of those, peer network in childhood determines to a large extent the mental health through the whole life course, while economic conditions and community environment are weakly associated with mental health. Furthermore, we find a distinct interaction mechanism linking those variables. The peer network completely mediates the effect of the community environment on the mental health of older adults and has a partial mediating effect on the economic conditions. Those findings suggest that social policies aimed at promoting older people's mental health in the context of the active ageing and health ageing strategy should go beyond the old age stage and target social conditions early in childhood.
    MeSH term(s) Aged ; Aging ; China/epidemiology ; Female ; Healthy Aging ; Humans ; Male ; Mental Health ; Surveys and Questionnaires
    Language English
    Publishing date 2021-06-14
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph18126420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dissecting the brain with spatially resolved multi-omics.

    Fangma, Yijia / Liu, Mengting / Liao, Jie / Chen, Zhong / Zheng, Yanrong

    Journal of pharmaceutical analysis

    2023  Volume 13, Issue 7, Page(s) 694–710

    Abstract: Recent studies have highlighted spatially resolved multi-omics technologies, including spatial genomics, transcriptomics, proteomics, and metabolomics, as powerful tools to decipher the spatial heterogeneity of the brain. Here, we focus on two major ... ...

    Abstract Recent studies have highlighted spatially resolved multi-omics technologies, including spatial genomics, transcriptomics, proteomics, and metabolomics, as powerful tools to decipher the spatial heterogeneity of the brain. Here, we focus on two major approaches in spatial transcriptomics (next-generation sequencing-based technologies and image-based technologies), and mass spectrometry imaging technologies used in spatial proteomics and spatial metabolomics. Furthermore, we discuss their applications in neuroscience, including building the brain atlas, uncovering gene expression patterns of neurons for special behaviors, deciphering the molecular basis of neuronal communication, and providing a more comprehensive explanation of the molecular mechanisms underlying central nervous system disorders. However, further efforts are still needed toward the integrative application of multi-omics technologies, including the real-time spatial multi-omics analysis in living cells, the detailed gene profile in a whole-brain view, and the combination of functional verification.
    Language English
    Publishing date 2023-04-10
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2630174-X
    ISSN 2214-0883 ; 2095-1779
    ISSN (online) 2214-0883
    ISSN 2095-1779
    DOI 10.1016/j.jpha.2023.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: METTL3-Mediated m

    Huang, Nana / Gao, Yue / Zhang, Mengting / Guo, Liangjie / Qin, Litao / Liao, Shixiu / Wang, Hongdan

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 894810

    Abstract: ... ...

    Abstract N
    Language English
    Publishing date 2022-06-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.894810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pomegranate-Like FeNC with Optimized FeN

    Li, Jiantao / Lin, Mengting / Huang, Wenzhong / Liao, Xiaobin / Ma, Yao / Zhou, Liang / Mai, Liqiang / Lu, Jun

    Small methods

    2023  Volume 7, Issue 7, Page(s) e2201664

    Abstract: Catalysts with FeNC moieties have demonstrated remarkable activity toward oxygen reduction reaction (ORR), but precise synthesis and configuration regulation of FeNC to achieve bi-functional catalytic sites for ORR and oxygen evolution reaction (OER) ...

    Abstract Catalysts with FeNC moieties have demonstrated remarkable activity toward oxygen reduction reaction (ORR), but precise synthesis and configuration regulation of FeNC to achieve bi-functional catalytic sites for ORR and oxygen evolution reaction (OER) remain a great challenge. Herein, a pomegranate-like catalyst with optimized FeN
    Language English
    Publishing date 2023-04-22
    Publishing country Germany
    Document type Journal Article
    ISSN 2366-9608
    ISSN (online) 2366-9608
    DOI 10.1002/smtd.202201664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: MLF-IOSC: Multi-Level Fusion Network With Independent Operation Search Cell for Low-Dose CT Denoising.

    Shen, Jinbo / Luo, Mengting / Liu, Han / Liao, Peixi / Chen, Hu / Zhang, Yi

    IEEE transactions on medical imaging

    2023  Volume 42, Issue 4, Page(s) 1145–1158

    Abstract: Computed tomography (CT) is widely used in clinical medicine, and low-dose CT (LDCT) has become popular to reduce potential patient harm during CT acquisition. However, LDCT aggravates the problem of noise and artifacts in CT images, increasing diagnosis ...

    Abstract Computed tomography (CT) is widely used in clinical medicine, and low-dose CT (LDCT) has become popular to reduce potential patient harm during CT acquisition. However, LDCT aggravates the problem of noise and artifacts in CT images, increasing diagnosis difficulty. Through deep learning, denoising CT images by artificial neural network has aroused great interest for medical imaging and has been hugely successful. We propose a framework to achieve excellent LDCT noise reduction using independent operation search cells, inspired by neural architecture search, and introduce the Laplacian to further improve image quality. Employing patch-based training, the proposed method can effectively eliminate CT image noise while retaining the original structures and details, hence significantly improving diagnosis efficiency and promoting LDCT clinical applications.
    MeSH term(s) Humans ; Signal-To-Noise Ratio ; Radiation Dosage ; Tomography, X-Ray Computed/methods ; Neural Networks, Computer ; Artifacts
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 622531-7
    ISSN 1558-254X ; 0278-0062
    ISSN (online) 1558-254X
    ISSN 0278-0062
    DOI 10.1109/TMI.2022.3224396
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2546: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: Intertemporal Dynamics of Birds and Their Response to Habitat Change in Nansha Wetland Park, Guangzhou from 2014 to 2018

    Huang Yuanxin / Li Mengting / Hu Huijian / Yuan Qianmin / Liang Jianchao / Li Mei / Liao Baowen

    Redai dili, Vol 43, Iss 1, Pp 71-

    2023  Volume 87

    Abstract: As an important land and water transition zone on Earth, wetlands are good places for birds to breed and roost. Bird monitoring has become an important index for assessing the biodiversity and ecological environment of a region. Nansha Wetland Park in ... ...

    Abstract As an important land and water transition zone on Earth, wetlands are good places for birds to breed and roost. Bird monitoring has become an important index for assessing the biodiversity and ecological environment of a region. Nansha Wetland Park in Guangzhou is rich in biological resources and provides an important resting and wintering ground for global migratory birds as it is located on their migration route from East Asia to Australasia. To understand the migration patterns and annual dynamic changes of birds in the Nansha Wetland Park, line- and point-transect surveys were conducted to collect bird species and abundance data from January 2014 to December 2018. First, our results showed that 139 birds were recorded during the study period, of which migrant species were dominant. Combined with the available literature, a total of 186 bird species were recorded, belonging to 17 orders and 49 families. Of these bird species, 165 are under various levels of protection. Second, while the interannual changes in bird abundance were substantial, those of bird species richness were not, indicating that bird species tended to reach maximum abundance in bird communities. When compared to bird abundance in 2015, the number of individuals was relatively stable in other years of investigation, and the number of investigated species was the highest in 2017. Finally, monthly changes in bird species were in accordance with the annual rhythms of migration. Specifically, bird species richness increased rapidly during the wintering period, but remained constant during the breeding period. In addition, the migration time of waterbirds tended to increase over time. This may be related to a warming climate that prompts birds to migrate earlier. Differences in habitat patches are important influencers of bird feeding habits, and thus bird distribution and habitat. Among the habitat patches investigated, birds were primarily distributed in shallow tidal flats with rich food sources and in tall and lush mangrove communities, such ...
    Keywords nansha wetland park ; avian community ; biodiversity ; migration patterns ; habitat selection ; Geography (General) ; G1-922
    Language Chinese
    Publishing date 2023-01-01T00:00:00Z
    Publisher Editorial Committee of Tropical Geography
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Global characteristics and trends of presbycusis research from 2002 to 2021: a bibliometric study.

    Lv, Hao / Gao, Ziang / Wang, Yunfei / Xie, Yulie / Guan, Mengting / Liao, Hua / Xu, Yu

    American journal of translational research

    2023  Volume 15, Issue 4, Page(s) 2407–2425

    Abstract: Background and objective: Age-related hearing loss, also termed presbycusis, is the most prevalent sensory impairment in older adults. Presbycusis research has considerably advanced over the past few decades, however, comprehensive and objective reports ...

    Abstract Background and objective: Age-related hearing loss, also termed presbycusis, is the most prevalent sensory impairment in older adults. Presbycusis research has considerably advanced over the past few decades, however, comprehensive and objective reports on the current state of presbycusis research are lacking. We used bibliometric methods to objectively analyzed the progress of presbycusis research over the past 20 years and to identify the research hotspots and emerging trends in this field.
    Methods: Eligible literature metadata published between 2002 and 2021 were obtained from the Web of Science Core Collection on September 1, 2022. Bibliometric tools including CiteSpace, VOSviewer, Bibliometrix R Package, Microsoft Excel 2019, and an online bibliometric platform were used to conduct bibliometric and visualized analyses.
    Results: A total of 1,693 publications related to presbycusis were retrieved. The number of publications increased continuously from 2002 to 2021, and the USA occupied the lead position in the field, with the highest research output. The most productive and influential institution, author, and journal were the University of California, Frisina DR of the University of South Florida, and Hearing Research, respectively. Co-citation cluster and trend topics analyses revealed that "cochlear synaptopathy", "oxidative stress", and "dementia" were the predominant foci of presbycusis research. Burst detection of keywords indicated that "auditory cortex" and "Alzheimer's disease" were the newly-emerged aspects.
    Conclusion: During the past two decades, presbycusis research has been flourishing. The current research foci are "cochlear synaptopathy", "oxidative stress", and "dementia". "Auditory cortex" and "Alzheimer's disease" may be potential future directions in this field. This bibliometric analysis represents the first quantitative overview of presbycusis research, thus providing valuable references and insights for scholars, medical practitioners, and policymakers concerned with this field.
    Language English
    Publishing date 2023-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Hypoglycemic Effect of Nobiletin via Gut Microbiota-Metabolism Axis on Hyperglycemic Mice.

    Liao, Xiaoshan / Zou, Jiaxuan / Wu, Mengting / Deng, Yudi / Shi, Jinwei / Hao, Yuting / Deng, Hong / Liao, Wenzhen

    Molecular nutrition & food research

    2023  Volume 67, Issue 12, Page(s) e2200289

    Abstract: Scope: Prediabetes and diabetes are major public health problems worldwide without specific cure currently. Gut microbes have been recognized as one of the vital therapeutic targets for diabetes. The exploration that nobiletin (NOB) whether affects gut ... ...

    Abstract Scope: Prediabetes and diabetes are major public health problems worldwide without specific cure currently. Gut microbes have been recognized as one of the vital therapeutic targets for diabetes. The exploration that nobiletin (NOB) whether affects gut microbes provides a scientific basis for its application.
    Methods and results: A hyperglycemia animal model is established using high-fat-fed ApoE
    Conclusion: NOB probably plays a vital role in the hypoglycemic effect and pancreatic islets protection by improving microbiota composition and gut metabolism.
    MeSH term(s) Mice ; Animals ; Hypoglycemic Agents/pharmacology ; Gastrointestinal Microbiome ; Mice, Obese ; Diet, High-Fat
    Chemical Substances Hypoglycemic Agents ; nobiletin (D65ILJ7WLY)
    Language English
    Publishing date 2023-03-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202200289
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  10. Article ; Online: HNRNPC mediated m

    Zhang, Mengting / Huang, Nana / Gao, Yue / Feng, Zhanqi / Kang, Bing / Guo, Han / Jiang, Jincheng / Liao, Shixiu / Wang, Hongdan

    Journal of reproductive immunology

    2023  Volume 160, Page(s) 104160

    Abstract: ... ...

    Abstract N
    MeSH term(s) Pregnancy ; Female ; Humans ; Methylation ; Homocysteine S-Methyltransferase/metabolism ; Heterogeneous-Nuclear Ribonucleoprotein Group C/metabolism ; Abortion, Habitual/genetics ; Abortion, Habitual/metabolism ; RNA, Messenger/metabolism
    Chemical Substances Homocysteine S-Methyltransferase (EC 2.1.1.10) ; 5-methyltetrahydrofolate (TYK22LML8F) ; Heterogeneous-Nuclear Ribonucleoprotein Group C ; RNA, Messenger ; HNRNPC protein, human
    Language English
    Publishing date 2023-10-04
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424421-7
    ISSN 1872-7603 ; 0165-0378
    ISSN (online) 1872-7603
    ISSN 0165-0378
    DOI 10.1016/j.jri.2023.104160
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1483: Show issues Location:
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