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  1. Article ; Online: Pharmacokinetics of Hu-Pi-Cheng-Qi decoction administered via enema to rats with acute pancreatitis.

    Wu, Qiu-Ting / Chen, Huan / Xiang, Jin / Tang, Wen-Fu / Wan, Mei-Hua

    Chinese medical journal

    2020  Volume 133, Issue 12, Page(s) 1510–1512

    MeSH term(s) Acute Disease ; Animals ; Drugs, Chinese Herbal/therapeutic use ; Enema ; Pancreatitis/drug therapy ; Rats ; Rats, Sprague-Dawley
    Chemical Substances Drugs, Chinese Herbal
    Language English
    Publishing date 2020-06-04
    Publishing country China
    Document type Letter
    ZDB-ID 127089-8
    ISSN 2542-5641 ; 0366-6999 ; 1002-0187
    ISSN (online) 2542-5641
    ISSN 0366-6999 ; 1002-0187
    DOI 10.1097/CM9.0000000000000853
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: In Memory of Professor Yan-Cheng Tang—A Brief Biography and Academic Contributions

    Wang, Jin-Xiu / Xiang, Qiu-Yun (Jenny) / Chen, Zhi-Duan / Qin, Hai-Ning / Lu, An-Min

    Harvard papers in botany. 2020 Dec. 31, v. 25, no. 2

    2020  

    Abstract: Professor Yan-Cheng Tang, also known as Yen-Cheng Tang, (汤彦承, given name Yan-Cheng, surname Tang ...

    Abstract Professor Yan-Cheng Tang, also known as Yen-Cheng Tang, (汤彦承, given name Yan-Cheng, surname Tang; abbreviated Y. C. Tang), passed away on August 6, 2016, in Beijing at the age of 90. He was a highly respected plant taxonomist for his massive contributions to plant taxonomy in China and for the number of botanists he influenced. A brief biography and a summary of his importance in the development of plant taxonomy in China during the latter half of the 20th century is presented.
    Keywords age ; botanists ; memory ; plant taxonomy ; China
    Language English
    Dates of publication 2020-1231
    Size p. 245-251.
    Publishing place Harvard University Botany Libraries
    Document type Article
    Note NAL-light
    ZDB-ID 2276307-7
    ISSN 1938-2944 ; 1043-4534
    ISSN (online) 1938-2944
    ISSN 1043-4534
    DOI 10.3100/hpib.v25iss2.2020.n14
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Effectiveness of Xin Jia Xuan Bai Cheng Qi Decoction in treating acute exacerbation of chronic obstructive pulmonary disease: study protocol for a multicentre, randomised, controlled trial.

    Jin, Jin / Zhang, Hongchun / Li, Demin / Jing, Yue / Sun, Zengtao / Feng, Jihong / Zhang, Hong / Zhang, Yan / Cui, Tianhong / Lei, Xiang / Zhang, Jing / Cheng, Qijian / Li, Erran

    BMJ open

    2019  Volume 9, Issue 11, Page(s) e030249

    Abstract: ... of follow-up, the efficacy and safety of Xin Jia Xuan Bai Cheng Qi Decoction in patients with AECOPD will be ...

    Abstract Introduction: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) brings a serious impact on patients' quality of life, and has extremely high morbidity and mortality worldwide. Although there are many therapies being developed to alleviate symptoms and reduce mortality, a few studies have supported which treatment method is the best. Traditional Chinese medicine (TCM) has shown good potential in the prevention and treatment of AECOPD, especially in terms of supplementation and reduction of dosage and adverse effect of Western medicine. The purpose of this study is to compare the effectiveness of combination of TCM and Western medicine with conventional therapy alone for AECOPD, and to ensure whether the combined therapy may reduce the use of systemic glucocorticoid in AECOPD without influencing efficacy.
    Methods and analysis: A multicentre, randomised, double-blind, placebo-controlled study was conducted to enrol a total of 360 eligible patients who will be randomised into integrated Chinese and Western medicine group A, B and Western standard Medicine group C. After 5 days of intervention and 1 month of follow-up, the efficacy and safety of Xin Jia Xuan Bai Cheng Qi Decoction in patients with AECOPD will be observed. The results of evaluation indicators include: clinical symptoms, biochemical indicators such as blood gas analysis, inflammatory markers, hospitalisation time, TCM syndrome evaluation, biological indicators such as airway, intestinal flora sequencing.
    Ethics and dissemination: This trail has been approved by the Ethics Committee of China-Japan Friendship Hospital. The results will be disseminated in international peer-reviewed journals and be presented in academic conferences. The results will also be disseminated to patients by telephone, inquiring on patient's poststudy health status during the follow-up.
    Trial registration number: ChiCTR1800016915.
    MeSH term(s) Acute Disease ; Adult ; Aged ; Aged, 80 and over ; Double-Blind Method ; Drugs, Chinese Herbal/pharmacology ; Female ; Humans ; Male ; Medicine, Chinese Traditional/methods ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Treatment Outcome
    Chemical Substances Drugs, Chinese Herbal ; xuanbai chengqi
    Language English
    Publishing date 2019-11-28
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, N.I.H., Intramural
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2019-030249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Corrigendum to Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. "Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration." Kidney Int. 2022;101:541-550.

    Zhang, Jie / Cai, Jing / Cui, Yu / Jiang, Shan / Wei, Jin / Kim, Young Chul / Chan, Jenna / Thalakola, Anish / Le, Thanh / Xu, Lan / Wang, Lei / Jiang, Kun / Wang, Ximing / Wang, Haibo / Cheng, Feng / Buggs, Jacentha / Koepsell, Hermann / Vallon, Volker / Liu, Ruisheng

    Kidney international

    2022  Volume 102, Issue 2, Page(s) 448

    Language English
    Publishing date 2022-07-20
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2022.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Da-Cheng-Qi Decoction Alleviates Intestinal Injury in Rats with Severe Acute Pancreatitis by Inhibiting the JAK2-STAT3 Signaling Pathway.

    Jin, Wenyin / Shen, Yinfeng

    Evidence-based complementary and alternative medicine : eCAM

    2019  Volume 2019, Page(s) 3909468

    Abstract: Objective: To investigate the effect of Da-Cheng-Qi decoction (DCQD) on treating intestinal injury ...

    Abstract Objective: To investigate the effect of Da-Cheng-Qi decoction (DCQD) on treating intestinal injury in rats with severe acute pancreatitis (SAP), based on the Janus kinase 2 (JAK2)/signal transducers and transcription 3 (STAT3) signaling pathway.
    Methods: Rats were randomly divided into the SAP group, SAP + ruxolitinib (JAK2 inhibitor) group, SAP + Stattic (STAT3 inhibitor) group, SAP + DCQD group, and sham operation group. They were further divided into 3-hour, 6-hour, 12-hour, and 18-hour subgroups. Levels of amylase and the inflammatory cytokines tumor necrosis factor-
    Results: Rats with SAP had severe changes in plasma levels of amylase and inflammatory cytokines and showed an overexpression of JAK2 mRNA, STAT3 mRNA, p-JAK2 protein, and p-STAT3 protein in the pancreas and terminal ileum. The events could be downregulated by treatment with DCQD, JAK2 inhibitor, and STAT3 inhibitor.
    Conclusions: In rats with SAP, DCQD ameliorated inflammatory cytokines and intestinal injury, which may be closely associated with the inhibition of the JAK2/STAT3 signaling pathway.
    Language English
    Publishing date 2019-08-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2019/3909468
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Effect of extraction on the acoustic vibrational properties of Picea jezoensis var. microsperma (Lindl.) W.C.Cheng & L.K.Fu

    Miao, Yuanyuan / Li, Rui / Qian, Xiaodong / Yin, Yuxue / Yang, Yang / Jin, Xianglong / Lin, Bin / Liu, Yixing / Liu, Zhenbo

    Annals of forest science. 2021 Mar., v. 78, no. 1

    2021  

    Abstract: ... Lindl.) W.C.Cheng & L.K.Fu) were improved by extraction treatment with deionized water, dichloromethane ...

    Abstract • KEY MESSAGE : The specific dynamic elastic modulus, acoustic radiation, logarithmic decrement, sound transmission parameter, and acoustic conversion efficiency of spruce wood (Picea jezoensis var. microsperma (Lindl.) W.C.Cheng & L.K.Fu) were improved by extraction treatment with deionized water, dichloromethane, benzyl alcohol, and ethanol. A larger improvement was achieved after extraction with benzoyl alcohol and dichloromethane extraction than by using ethanol and deionized water. • CONTEXT : It is necessary to improve the acoustic vibrational properties of wood to solve the problem of resource shortage of wood with excellent acoustic vibrational properties for the soundboards of musical instruments and to improve the use value of wood. • AIMS : The effects of extraction treatment with deionized water, dichloromethane, benzyl alcohol, and ethanol on the acoustic vibrational properties of spruce wood were evaluated. • METHODS : After the acoustic vibrational properties of untreated wood samples were measured using the free-free flexural vibration test method with a fast Fourier transform spectrum analyzer (FFT, CF-5220Z), extraction treatment of the wood samples was separately performed with deionized water, dichloromethane, benzyl alcohol, and ethanol for 15 days at room temperature and pressure, followed by drying. The acoustic vibrational properties of the treated wood samples were then measured, and the effect of extraction treatment on the acoustic vibrational properties was analyzed. • RESULTS : The increase in the specific dynamic elastic modulus was highest (14.5%) after the benzyl alcohol treatment. The acoustic radiation clearly improved after the ethanol treatment (18.1%). The acoustic impedance of the wood treated by dichloromethane extraction decreased significantly (−4.35%), while the logarithmic decrement was significantly reduced (−52.0%) by benzyl alcohol treatment. From the viewpoint of energy utilization, with benzyl alcohol treatment, the acoustic conversion efficiency and transmission parameter increased by 124% and 125%, respectively. • CONCLUSION : The degree of improvement in the acoustic vibrational properties of wood differed depending on the solvent used. Greater improvement was observed after extraction with benzoyl alcohol and dichloromethane as compared to ethanol and deionized water.
    Keywords Picea jezoensis ; acoustic impedance ; ambient temperature ; benzyl alcohol ; energy ; ethanol ; forests ; methylene chloride ; modulus of elasticity ; solvents ; vibration ; wood
    Language English
    Dates of publication 2021-03
    Size p. 24.
    Publishing place Springer Paris
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1464978-0
    ISSN 1297-966X ; 1286-4560
    ISSN (online) 1297-966X
    ISSN 1286-4560
    DOI 10.1007/s13595-021-01048-1
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Tissue Pharmacology of Da-Cheng-Qi Decoction in Experimental Acute Pancreatitis in Rats.

    Zhao, Xianlin / Zhang, Yumei / Li, Juan / Wan, Meihua / Zhu, Shifeng / Guo, Hui / Xiang, Jin / Thrower, Edwin C / Tang, Wenfu

    Evidence-based complementary and alternative medicine : eCAM

    2015  Volume 2015, Page(s) 283175

    Abstract: Objectives. The Chinese herbal medicine Da-Cheng-Qi Decoction (DCQD) can ameliorate the severity ...

    Abstract Objectives. The Chinese herbal medicine Da-Cheng-Qi Decoction (DCQD) can ameliorate the severity of acute pancreatitis (AP). However, the potential pharmacological mechanism remains unclear. This study explored the potential effective components and the pharmacokinetic characteristics of DCQD in target tissue in experimental acute pancreatitis in rats. Methods. Acute pancreatitis-like symptoms were first induced in rats and then they were given different doses of DCQD (6 g/kg, 12 g/kg, and 24 g/kg body weight) orally. Tissue drug concentration, tissue pathological score, and inflammatory mediators in pancreas, intestine, and lung tissues of rats were examined after 24 hours, respectively. Results. Major components of DCQD could be found in target tissues and their concentrations increased in conjunction with the intake dose of DCQD. The high-dose compounds showed maximal effect on altering levels of anti-inflammatory (interleukin-4 and interleukin-10) and proinflammatory markers (tumor necrosis factor α and interleukin-6) and ameliorating the pathological damage in target tissues (P < 0.05). Conclusions. DCQD could alleviate pancreatic, intestinal, and lung injury by altering levels of inflammatory cytokines in AP rats with tissue distribution of its components.
    Language English
    Publishing date 2015-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2015/283175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pharmacokinetics of Hu-Pi-Cheng-Qi decoction administered via enema to rats with acute pancreatitis

    Qiu-Ting Wu / Huan Chen / Jin Xiang / Wen-Fu Tang / Mei-Hua Wan / Ning-Ning Wang

    Chinese Medical Journal, Vol 133, Iss 12, Pp 1510-

    2020  Volume 1512

    Keywords Medicine ; R
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Wolters Kluwer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Da-Cheng-Qi Decoction Combined with Conventional Treatment for Treating Postsurgical Gastrointestinal Dysfunction.

    Jin, Wei / Li, Qingjie / Luo, Xiaoqiong / Zhong, Juan / Song, Yang / Li, Yiwei

    Evidence-based complementary and alternative medicine : eCAM

    2017  Volume 2017, Page(s) 1987396

    Abstract: Aim: To assess the current clinical evidence of the effectiveness of Da-Cheng-Qi Decoction (DCQD ... RCTs) of Da-Cheng-Qi Decoction (DCQD) to PGD were searched from available major electronic databases ...

    Abstract Aim: To assess the current clinical evidence of the effectiveness of Da-Cheng-Qi Decoction (DCQD) for the treatment of Postoperative gastrointestinal dysfunction (PGD).
    Methods: Randomized controlled trails (RCTs) of Da-Cheng-Qi Decoction (DCQD) to PGD were searched from available major electronic databases to September 2016. The intervention must be a modified DCQD or DCQD integrated to Western Medicine (WM) compared with WM or placebo or blank. The main outcome index was clinical effectiveness and improvement of major symptoms. Data extraction, data analysis, and methodological quality assessment are conducted according to the Cochrane Handbook for Systematic Review of Interventions, version 5.0.2. RevMan 5.3 software was applied to our data analyses.
    Results: Seven RCTs involving 494 participants were recruited and identified. The methodological quality of all trials were assessed and generally of low-level. Those studies were published between 2004 and 2013. All 7 studies which used herbals (modified DCQD) integrate WM in test group compared with WM as the intervention and only one study (Sunyouxu 2013) integrates placebo to Western Medicine as the control group intervention. The treatment course was 1 week to 2 weeks. Evaluation of intervention effectiveness consists of the clinical effective rate indicator and the PGD symptoms indicator including time of borborygmus, time of gastrointestinal exhaust, and time of defecate. The clinical effectiveness results are beneficial to the test group.
    Conclusion: DCQD could improve PGD symptoms and promotion clinical effectiveness.
    Language English
    Publishing date 2017-05-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2017/1987396
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effects of Chai-Qin-Cheng-Qi decoction () on acute pancreatitis-associated lung injury in mice with acute necrotizing pancreatitis.

    Huang, Lei / Wang, Ming-Hao / Cheng, Zheng-Yu / Xue, Ping / Jin, Tao / Yang, Xiao-Nan / Xia, Qing

    Chinese journal of integrative medicine

    2012  

    Abstract: OBJECTIVE: To investigate the effects of Chai-Qin-Cheng-Qi Decoction (, CQCQD ...

    Abstract OBJECTIVE: To investigate the effects of Chai-Qin-Cheng-Qi Decoction (, CQCQD) on acute pancreatitis-associated lung injury in mice with acute necrotizing pancreatitis (ANP). METHODS: Thirty healthy mice were randomly divided into three groups: an ANP group (ANP+placebo, n=10); a treatment group (ANP+CQCQD, n=10); and a control group (normal mice+placebo, n=10). ANP was induced by intraperitoneal injection with 8% L-arginine (4 μg/kg), and the control group was injected with normal saline. The treatment group received CQCQD (20 mL/kg), and the ANP and control groups received placebo (sucrose and starch) intragastrically at 2 h intervals. After the third intragastric administration, blood, pancreatic tissues and right lung tissues were collected for measurement of serum interleukin-6 (IL-6) and interleukin-10 (IL-10) by enzyme-linked immunosorbent assay, and the expression of heat shock protein 70 (HSP70) in lung tissue was determined by Western blot analysis. Pathological changes of pancreatic tissue and lung tissue were examined. RESULTS: Serum IL-6 was significantly higher in the ANP group compared with the control and the treatment groups (1589.63±377.28 vs. 927.46±210.42 pg/mL, P<0.05, and 1589.63±377.28 vs. 1107.73±351.62 pg/mL, P<0.05, respectively). The IL-10 concentration was significantly lower in the ANP group compared with the treatment group (920.64±101.68 vs. 1177.84±201.72 pg/mL, P<0.05), but no signififi cant difference was found between the ANP and control groups and between the treatment and control groups. The expression level of HSP70 in the ANP and control groups was signififi cantly lower than in the treatment group (0.93±0.03 vs. 1.42±0.21, P<0.01, and 0.81±0.09 vs. 1.42±0.21, P<0.01, respectively). There was no signififi cant difference in HSP70 levels between the ANP and control groups. Histological scores of pancreatic and lung tissue were significantly decreased in the treatment group compared with the ANP groups (4.50±0.54 vs. 6.20±1.65, P<0.05, and 3.00±0.63 vs. 3.87±0.83, P<0.05, respectively). CONCLUSIONS: The incidence of acute pancreatitisassociated lung injury in ANP mice correlates positively with serum IL-6 concentration. CQCQD may inhibit IL-6 induction and increase IL-10 concentration and HSP70 expression, effectively reducing lung injury.
    Language English
    Publishing date 2012-09-21
    Publishing country China
    Document type Journal Article
    ZDB-ID 2171254-2
    ISSN 1993-0402 ; 1672-0415
    ISSN (online) 1993-0402
    ISSN 1672-0415
    DOI 10.1007/s11655-012-1207-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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