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  1. Book ; Online ; E-Book: Advances in applied microbiology / Volume 110 /

    Gadd, Geoffrey M. / Sariaslani, Sima

    (Advances in applied microbiology)

    2020  

    Author's details edited by Geoffrey M. Gadd, Sima Sariaslani
    Series title Advances in applied microbiology
    Keywords Industrial microbiology
    Subject code 660.62
    Language English
    Size 1 online resource (viii, 217 pages) :, illustrations.
    Publisher Academic Press
    Publishing place Cambridge, MA
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-12-820703-5 ; 978-0-12-820703-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Comorbid psychiatric conditions with temporomandibular disorders (TMD) in a tertiary referral clinic.

    Gadd, Madeleine / Attard, Alan / Green, Jason / Elledge, Ross O C

    The British journal of oral & maxillofacial surgery

    2024  

    Abstract: Patients with chronic pain have a higher prevalence of mood disorders with depression and anxiety contributing to higher pain intensity, emotional allodynia, and neuro-anatomical changes. We sought to quantify the prevalence of psychiatric comorbidities ( ...

    Abstract Patients with chronic pain have a higher prevalence of mood disorders with depression and anxiety contributing to higher pain intensity, emotional allodynia, and neuro-anatomical changes. We sought to quantify the prevalence of psychiatric comorbidities (PCs) in a tertiary referral clinic for temporomandibular disorders (TMDs). Medical records of all patients attending clinics run by three tertiary temporomandibular joint (TMJ) surgeons for the period January to April 2022 inclusive were audited for the prevalence of concomitant psychiatric conditions. A total of 166 patients were identified with a female to male ratio of 5:1 and mean (SD) age of 45.1 (15.2) years. A total of 124 (89.9%) of patients were tertiary referrals and 72 (43.4%) patients had concomitant psychiatric diagnoses, with 58 (34.9%) being on some form of psychotropic medication (PM) (patients on anticonvulsants for neuropathic pain were not included). A majority of 136 (81.9%) patients had some form of intervention (including Dysport® and minimally invasive surgery) which appeared more common in patients with co-existing psychiatric issues (p < 0.05). A higher proportion of mental health issues exist among TMD patients in a tertiary referral clinic than would be expected in the general population. We suggest a holistic approach to patients with multidisciplinary care taking into account this prevalence to ensure decision-making that contextualises the patient and not simply the pathology.
    Language English
    Publishing date 2024-01-11
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 605685-4
    ISSN 1532-1940 ; 0266-4356
    ISSN (online) 1532-1940
    ISSN 0266-4356
    DOI 10.1016/j.bjoms.2023.12.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online ; E-Book: Advances in applied microbiology / Volume eighty one /

    Sariaslani, Sima / Gadd, Geoffrey M.

    (Advances in Applied Microbiology ; Volume 81)

    2012  

    Abstract: Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent ... ...

    Author's details edited by Sima Sariaslani, Geoffrey M. Gadd
    Series title Advances in Applied Microbiology ; Volume 81
    Abstract Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndr
    Keywords Microbiology/Research ; Microbiology/Study and teaching
    Subject code 660.62
    Language English
    Size 1 online resource (295 p.)
    Edition 1st ed.
    Publisher Academic Press, an imprint of Elsevier
    Publishing place Amsterdam
    Document type Book ; Online ; E-Book
    Note English ; Description based upon print version of record.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-283-61984-9 ; 9786613932297 ; 0-12-398288-X ; 0-12-394382-5 ; 978-1-283-61984-4 ; 6613932299 ; 978-0-12-398288-9 ; 978-0-12-394382-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Accumulation and effects of cadmium on sulphate-reducing bacterial biofilms.

    White, Chris / Gadd, Geoffrey M

    Microbiology (Reading, England)

    2021  Volume 144, Issue 5, Page(s) 1407–1415

    Abstract: Biofilms comprising a pure and a mixed culture of sulphate-reducing bacteria (SRB) were grown in continuous culture. When exposed to 20 or 200 μM Cd, both cultures accumulated Cd but the mixed culture accumulated more and continued to accumulate Cd ... ...

    Abstract Biofilms comprising a pure and a mixed culture of sulphate-reducing bacteria (SRB) were grown in continuous culture. When exposed to 20 or 200 μM Cd, both cultures accumulated Cd but the mixed culture accumulated more and continued to accumulate Cd during the experiment, whereas accumulation by the pure cultures ceased after 4-6 d. Unlike the pure culture, the mixed culture also accumulated both protein and carbohydrate throughout the experiment proportionally to Cd which showed that accumulation required the production of biofilm material. Electron microscopy showed the presence of polysaccharide and particulates in both pure and mixed cultures, irrespective of the presence of Cd. However, energy-dispersive X-ray analysis (EDXA) showed that accumulation of Cd in the form of CdS occurred in biofilms exposed to Cd while back-scattered electron imaging of sections indicated that the accumulation of Cd was localized in a superficial layer of the biofilm. The mechanism of uptake, therefore, appeared to be entrapment and/or precipitation of CdS at the biofilm surface. The relatively low Cd uptake by the pure culture biofilm was attributed to its less efficient growth and polysaccharide production. These results indicate that mixed SRB cultures are more effective than pure cultures for metal removal and underlines significant differences between the biology of pure and mixed cultures.
    Language English
    Publishing date 2021-01-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1180712-x
    ISSN 1465-2080 ; 1350-0872
    ISSN (online) 1465-2080
    ISSN 1350-0872
    DOI 10.1099/00221287-144-5-1407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Conference proceedings: Fungi in the environment

    Gadd, Geoffrey M.

    [Symposium on Fungi in the Environment held at the University of Nottingham in September 2004]

    (British Mycological Society symposium series ; 25)

    2007  

    Institution British Mycological Society
    Event/congress Symposium on Fungi in the Environment (2004, Nottingham)
    Author's details [British Mycological Society Symposium]. Ed. by Geoffrey Michael Gadd
    Series title British Mycological Society symposium series ; 25
    Collection
    Language English
    Size XIX, 386 S. : Ill., graph. Darst., Kt.
    Edition [1. ed.]
    Publisher Cambridge Univ. Press
    Publishing place Cambridge u.a.
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    Note Literaturangaben
    HBZ-ID HT014798731
    ISBN 0-521-85029-0 ; 978-0-521-85029-2
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  6. Book: Micro-organisms and earth systems

    Gadd, Geoffrey M.

    advances in geomicrobiology

    (Symposia of the Society for General Microbiology ; 65)

    2005  

    Institution Society for General Microbiology
    Author's details Sixty-fifth symposium of the Society for General Microbiology, held at Keele University September 2005. Ed. by G. M. Gadd
    Series title Symposia of the Society for General Microbiology ; 65
    Symposium of the Society for General Microbiology
    Collection Symposium of the Society for General Microbiology
    Keywords Geomikrobiologie
    Subject Lithobiontik
    Language English
    Size XII, 376 S. : Ill., graph. Darst.
    Publisher Cambridge Univ. Press
    Publishing place Cambridge
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT014521258
    ISBN 978-0-521-86222-6 ; 978-0521-86222-6 ; 0521-86222-1 ; 0-521-86222-1
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Youth sport participation, injury history, and current physical activity among young adults.

    Gadd, Noah / Hoch, Johanna M / McKay, Chloe / Tinsley, Jennifer / Dlugonski, Deirdre

    Journal of American college health : J of ACH

    2023  , Page(s) 1–6

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-07-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604907-2
    ISSN 1940-3208 ; 0744-8481
    ISSN (online) 1940-3208
    ISSN 0744-8481
    DOI 10.1080/07448481.2023.2230303
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2.

    Davies, Faith C J / Marshall, Grant F / Pegram, Eleanor / Gadd, Danni / Abbott, Catherine M

    Molecular and cellular neurosciences

    2023  Volume 126, Page(s) 103879

    Abstract: All vertebrate species express two independently-encoded forms of translation elongation factor eEF1A. In humans and mice eEF1A1 and eEF1A2 are 92 % identical at the amino acid level, but the well conserved developmental switch between the two variants ... ...

    Abstract All vertebrate species express two independently-encoded forms of translation elongation factor eEF1A. In humans and mice eEF1A1 and eEF1A2 are 92 % identical at the amino acid level, but the well conserved developmental switch between the two variants in specific tissues suggests the existence of important functional differences. Heterozygous mutations in eEF1A2 result in neurodevelopmental disorders in humans; the mechanism of pathogenicity is unclear, but one hypothesis is that there is a dominant negative effect on eEF1A1 during development. The high degree of similarity between the eEF1A proteins has complicated expression analysis in the past; here we describe a gene edited mouse line in which we have introduced a V5 tag in the gene encoding eEF1A2. Expression analysis using anti-V5 and anti-eEF1A1 antibodies demonstrates that, in contrast to the prevailing view that eEF1A2 is only expressed postnatally, it is expressed from as early as E11.5 in the developing neural tube. Two colour immunofluorescence also reveals coordinated switching between eEF1A1 and eEF1A2 in different regions of postnatal brain. Completely reciprocal expression of the two variants is seen in post-weaning mouse brain with eEF1A1 expressed in oligodendrocytes and astrocytes and eEF1A2 in neuronal soma. Although eEF1A1 is absent from neuronal cell bodies after development, it is widely expressed in axons. This expression does not appear to coincide with myelin sheaths originating from oligodendrocytes but rather results from localised translation within the axon, suggesting that both variants are transcribed in neurons but show completely distinct subcellular localisation at the protein level. These findings will form an underlying framework for understanding how missense mutations in eEF1A2 result in neurodevelopmental disorders.
    MeSH term(s) Animals ; Humans ; Mice ; Mutation ; Mutation, Missense ; Neurodevelopmental Disorders ; Neurons/metabolism ; Peptide Elongation Factor 1/genetics ; Peptide Elongation Factor 1/chemistry ; Peptide Elongation Factor 1/metabolism
    Chemical Substances Peptide Elongation Factor 1 ; Eef1a1 protein, mouse ; Eef1a2 protein, mouse
    Language English
    Publishing date 2023-07-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1046640-x
    ISSN 1095-9327 ; 1044-7431
    ISSN (online) 1095-9327
    ISSN 1044-7431
    DOI 10.1016/j.mcn.2023.103879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Braden Scale cumulative score versus subscale scores: are we missing opportunities for pressure ulcer prevention?

    Gadd, Molly M

    Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society

    2014  Volume 41, Issue 1, Page(s) 86–89

    Abstract: Background: Hospital-acquired pressure ulcer incidence rates continue to rise in the United States in the acute care setting despite efforts to extinguish them, and pressure ulcers are a nursing-sensitive quality indicator. The Braden Scale for ... ...

    Abstract Background: Hospital-acquired pressure ulcer incidence rates continue to rise in the United States in the acute care setting despite efforts to extinguish them, and pressure ulcers are a nursing-sensitive quality indicator. The Braden Scale for Predicting Pressure Sore Risk instrument has been shown to be a valid and reliable instrument for assessing pressure ulcer risk.
    Case: This case study represented 1 patient out of a chart audit that reviewed 20 patients with confirmed hospital-acquired pressure ulcers. The goal of the audit was to determine whether these ulcers might be avoided if preventive interventions based on Braden subscale scores versus the cumulative score were implemented.
    Conclusion: This case study describes a patient who, deemed at low risk for pressure ulcer development based on cumulative Braden Scale, may have benefited from interventions based on the subscale scores of sensory perception, activity, and mobility. Further research is needed to determine whether interventions based on subscales may be effective for preventing pressure ulcers when compared to a protocol based exclusively on the cumulative score.
    MeSH term(s) Aged ; Hospitalization ; Humans ; Immobilization ; Male ; Pressure Ulcer/epidemiology ; Pressure Ulcer/nursing ; Pressure Ulcer/prevention & control ; Risk Assessment/methods ; Sensation
    Language English
    Publishing date 2014-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1188388-1
    ISSN 1528-3976 ; 1071-5754
    ISSN (online) 1528-3976
    ISSN 1071-5754
    DOI 10.1097/01.WON.0000438017.83110.6c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Oral vaccination of foxes and raccoon dogs against rabies with the 3rd generation oral rabies virus vaccine, SPBN GASGAS, in Finland.

    Vos, Ad / Nokireki, Tiina / Isomursu, Marja / Gadd, Tuija / Kovacs, Ferenc

    Acta veterinaria Scandinavica

    2021  Volume 63, Issue 1, Page(s) 40

    Abstract: Background: To prevent re-emergence of wildlife-mediated rabies in Finland, oral rabies vaccine baits are distributed every year during autumn in southern Finland in a vaccination zone bordering Russia. Recently, Finland introduced a 3rd generation oral ...

    Abstract Background: To prevent re-emergence of wildlife-mediated rabies in Finland, oral rabies vaccine baits are distributed every year during autumn in southern Finland in a vaccination zone bordering Russia. Recently, Finland introduced a 3rd generation oral rabies virus vaccine bait. By analysing bait uptake and seroconversion in red foxes and raccoon dogs, the field efficacy of this new vaccine strain, SPBN GASGAS, was compared with the originally used highly efficacious 1st generation vaccine SAD B19.
    Results: Overall, 74.6% and 53.9% of the animals submitted from the vaccination area after the campaigns (2017-2019) tested positive for the presence of the bait marker and anti-rabiesvirus antibodies, respectively. No significant difference was observed between years, species and vaccine.
    Conclusions: The field performance of the highly attenuated 3rd generation oral rabies vaccine, SPBN GASGAS, in terms of bait uptake and seroconversion was similar to the 1st generation vaccine, SAD B19, and therefore offers a suitable alternative.
    MeSH term(s) Administration, Oral ; Animals ; Finland ; Foxes ; Rabies/prevention & control ; Rabies/veterinary ; Rabies Vaccines ; Rabies virus ; Raccoon Dogs ; Vaccination/veterinary
    Chemical Substances Rabies Vaccines
    Language English
    Publishing date 2021-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 40137-7
    ISSN 1751-0147 ; 0044-605X
    ISSN (online) 1751-0147
    ISSN 0044-605X
    DOI 10.1186/s13028-021-00605-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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