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  1. Article: Communicating Science: A Shared Responsibility.

    Hanafiah, Khayriyyah Mohd

    The Malaysian journal of medical sciences : MJMS

    2018  Volume 25, Issue 5, Page(s) 1–5

    Abstract: Malaysia faces increasing alienation of science in the community. While this is a global and multifaceted issue, science communication plays a pivotal role in making science more intuitive for the general public. Scientific communication requires brevity ...

    Abstract Malaysia faces increasing alienation of science in the community. While this is a global and multifaceted issue, science communication plays a pivotal role in making science more intuitive for the general public. Scientific communication requires brevity and accuracy-targeted to an interested audience hungry for details. Conversely, science communication requires conveying the bigger picture with clarity and impact-targeted to an audience that needs to be courted by an idea. The challenge for scientists and academics is to find a balance between details sufficient to carry the scientific "truth", while appeasing the human desire for ease and simplicity. Critically, science communication is a powerful device to tackle the increasingly urgent challenge of sustaining scientific progress in a post-truth era. Here, I discuss the role of scientists, key elements of science communication, and propose instruction of Philosophy of Science and debate to equip scientists with the crucial skills required for impactful science communication.
    Language English
    Publishing date 2018-10-30
    Publishing country Malaysia
    Document type Editorial
    ZDB-ID 2197205-9
    ISSN 2180-4303 ; 1394-195X
    ISSN (online) 2180-4303
    ISSN 1394-195X
    DOI 10.21315/mjms2018.25.5.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Application of Proteomics to the Study of the Therapeutics and Pathogenicity of

    Aziz, Ahmad Fudail Eiyad / Roshidi, Norhamizah / Othman, Nurulhasanah / Mohd Hanafiah, Khayriyyah / Arifin, Norsyahida

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 11

    Abstract: ... Giardia ... ...

    Abstract Giardia duodenalis
    Language English
    Publishing date 2022-11-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12112744
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dimeric immunoglobulin A as a novel diagnostic marker of measles infection.

    Mohd Hanafiah, Khayriyyah / Hiebert, Joanne / Zubach, Vanessa / Severini, Alberto / Anderson, David A / Drummer, Heidi E

    Microbiology spectrum

    2023  Volume 12, Issue 1, Page(s) e0343723

    Abstract: Importance: The world is facing a measles resurgence, and improved diagnostic tests for measles infection are an urgent World Health Organization research priority. Detection of measles-specific immunoglobulin M (IgM) as a standard diagnostic test has ... ...

    Abstract Importance: The world is facing a measles resurgence, and improved diagnostic tests for measles infection are an urgent World Health Organization research priority. Detection of measles-specific immunoglobulin M (IgM) as a standard diagnostic test has low positive predictive value in elimination settings, and there is a need for new biomarkers of measles infection to enable enhanced surveillance and response to outbreaks. We demonstrate the detection of measles-specific dimeric immunoglobulin A (dIgA) in patients with confirmed measles infections using a new indirect enzyme-linked immunosorbent assay protocol that selects for the dIgA fraction from total IgA in the blood. The magnitude of measles-specific dIgA responses showed a low correlation with IgM responses, and our results highlight the potential of dIgA for further development as an alternative and/or complementary biomarker to IgM for serological diagnosis of measles infection.
    MeSH term(s) Humans ; Immunoglobulin A ; Antibodies, Viral ; Measles/diagnosis ; Measles/epidemiology ; Predictive Value of Tests ; Immunoglobulin M ; Biomarkers
    Chemical Substances Immunoglobulin A ; Antibodies, Viral ; Immunoglobulin M ; Biomarkers
    Language English
    Publishing date 2023-12-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03437-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effective Communication at Different Phases of COVID-19 Prevention: Roles, Enablers and Barriers.

    Mohd Hanafiah, Khayriyyah / Ng, Celine / Wan, Abdul Matiin

    Viruses

    2021  Volume 13, Issue 6

    Abstract: In an age of globalisation and hyperconnectivity, the COVID-19 pandemic has caused unprecedented and sustained impact worldwide. This article discusses issues related to (science) communication at different phases of the COVID-19 epidemic timeline. We ... ...

    Abstract In an age of globalisation and hyperconnectivity, the COVID-19 pandemic has caused unprecedented and sustained impact worldwide. This article discusses issues related to (science) communication at different phases of the COVID-19 epidemic timeline. We consider the role of communication for prevention from the ecological perspective, taking into consideration that many emerging pathogens, including COVID-19, likely arise in part due to anthropogenic changes to natural environments. Communication forms part of the early response setting the scene for public buy-in of public health interventions at the start of an outbreak, as well as to maintain precautions over time. Finally, communication is a key element in increasing acceptance for new tools that require mass uptake to be effective, as seen with roll-out challenges for the COVID-19 vaccines, which faced heightened concerns of efficacy and safety while mired with rampant misinformation. Ultimately, strategies for prevention of viral epidemics such as COVID-19 must include communication strategies at the forefront to reduce the risk of the emergence of new diseases and enhance efforts to control their spread and burden. Despite key themes emerging, what constitutes effective communication strategies for different people and contexts needs to be investigated further.
    MeSH term(s) COVID-19/prevention & control ; COVID-19/psychology ; Communication ; Disease Outbreaks/prevention & control ; Humans ; Public Health/education ; Public Health/methods ; Social Media
    Language English
    Publishing date 2021-06-03
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13061058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effective Communication at Different Phases of COVID-19 Prevention

    Khayriyyah Mohd Hanafiah / Celine Ng / Abdul Matiin Wan

    Viruses, Vol 13, Iss 1058, p

    Roles, Enablers and Barriers

    2021  Volume 1058

    Abstract: In an age of globalisation and hyperconnectivity, the COVID-19 pandemic has caused unprecedented and sustained impact worldwide. This article discusses issues related to (science) communication at different phases of the COVID-19 epidemic timeline. We ... ...

    Abstract In an age of globalisation and hyperconnectivity, the COVID-19 pandemic has caused unprecedented and sustained impact worldwide. This article discusses issues related to (science) communication at different phases of the COVID-19 epidemic timeline. We consider the role of communication for prevention from the ecological perspective, taking into consideration that many emerging pathogens, including COVID-19, likely arise in part due to anthropogenic changes to natural environments. Communication forms part of the early response setting the scene for public buy-in of public health interventions at the start of an outbreak, as well as to maintain precautions over time. Finally, communication is a key element in increasing acceptance for new tools that require mass uptake to be effective, as seen with roll-out challenges for the COVID-19 vaccines, which faced heightened concerns of efficacy and safety while mired with rampant misinformation. Ultimately, strategies for prevention of viral epidemics such as COVID-19 must include communication strategies at the forefront to reduce the risk of the emergence of new diseases and enhance efforts to control their spread and burden. Despite key themes emerging, what constitutes effective communication strategies for different people and contexts needs to be investigated further.
    Keywords communication ; science communication ; COVID-19 ; zoonosis ; prevention ; One Health ; Microbiology ; QR1-502
    Subject code 360
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: An Observational Case-Control Study to Determine Human Immunodeficiency Virus and Host Factor Influence on Biomarker Distribution and Serodiagnostic Potential in Adult Pulmonary Tuberculosis.

    Mohd Hanafiah, Khayriyyah / Garcia, Mary Louise / Anderson, David Andrew

    Tropical medicine and infectious disease

    2019  Volume 4, Issue 2

    Abstract: Influence of host factors, including human immunodeficiency virus (HIV) co-infection, on the distribution and diagnostic potential of previously evaluated biomarkers of pulmonary tuberculosis (PTB), such as anti-antigen 60 (A60) immunoglobulin (Ig) G, ... ...

    Abstract Influence of host factors, including human immunodeficiency virus (HIV) co-infection, on the distribution and diagnostic potential of previously evaluated biomarkers of pulmonary tuberculosis (PTB), such as anti-antigen 60 (A60) immunoglobulin (Ig) G, anti-A60 IgA, and C-reactive protein (CRP), remain unclear. Anti-A60 IgG, anti-A60 IgA, and CRP in PTB and non-PTB patient sera (
    Language English
    Publishing date 2019-03-31
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed4020057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Application of Proteomics to the Study of the Therapeutics and Pathogenicity of Giardia duodenalis

    Ahmad Fudail Eiyad Aziz / Norhamizah Roshidi / Nurulhasanah Othman / Khayriyyah Mohd Hanafiah / Norsyahida Arifin

    Diagnostics, Vol 12, Iss 2744, p

    2022  Volume 2744

    Abstract: Giardia duodenalis remains a neglected tropical disease. A key feature of the sustained transmission of Giardia is the ability to form environmentally resistant cysts. For the last 38 years, proteomics has been utilised to study various aspects of the ... ...

    Abstract Giardia duodenalis remains a neglected tropical disease. A key feature of the sustained transmission of Giardia is the ability to form environmentally resistant cysts. For the last 38 years, proteomics has been utilised to study various aspects of the parasite across different life cycle stages. Thirty-one articles have been published in PubMed from 2012 to 2022 related to the proteomics of G. duodenalis . Currently, mass spectrometry with LC-MS/MS and MALDI-TOF/TOF has been commonly utilised in proteomic analyses of Giardia , which enables researchers to determine potential candidates for diagnostic biomarkers as well as vaccine and drug targets, in addition to allowing them to investigate the virulence of giardiasis, the pathogenicity mechanisms of G. duodenalis , and the post-translational modifications of Giardia proteins throughout encystation. Over the last decade, valuable information from proteomics analyses of G. duodenalis has been discovered in terms of the pathogenesis and virulence of Giardia , which may provide guidance for the development of better means with which to prevent and reduce the impacts of giardiasis. Nonetheless, there is room for improving proteomics analyses of G. duodenalis , since genomic sequences for additional assemblages of Giardia have uncovered previously unknown proteins associated with the Giardia proteome. Therefore, this paper aims to review the applications of proteomics for the characterisation of G. duodenalis pathogenicity and the discovery of novel vaccine as well as drug targets, in addition to proposing some general directions for future Giardia proteomic research.
    Keywords Giardia duodenalis ; proteomics ; vaccine and drug development ; virulence ; pathogenicity mechanism ; PTMs ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Effective Communication at Different Phases of COVID-19 Prevention: Roles, Enablers and Barriers

    Mohd Hanafiah, Khayriyyah / Ng, Celine / Wan, Abdul Matiin

    Viruses. 2021 June 03, v. 13, no. 6

    2021  

    Abstract: In an age of globalisation and hyperconnectivity, the COVID-19 pandemic has caused unprecedented and sustained impact worldwide. This article discusses issues related to (science) communication at different phases of the COVID-19 epidemic timeline. We ... ...

    Abstract In an age of globalisation and hyperconnectivity, the COVID-19 pandemic has caused unprecedented and sustained impact worldwide. This article discusses issues related to (science) communication at different phases of the COVID-19 epidemic timeline. We consider the role of communication for prevention from the ecological perspective, taking into consideration that many emerging pathogens, including COVID-19, likely arise in part due to anthropogenic changes to natural environments. Communication forms part of the early response setting the scene for public buy-in of public health interventions at the start of an outbreak, as well as to maintain precautions over time. Finally, communication is a key element in increasing acceptance for new tools that require mass uptake to be effective, as seen with roll-out challenges for the COVID-19 vaccines, which faced heightened concerns of efficacy and safety while mired with rampant misinformation. Ultimately, strategies for prevention of viral epidemics such as COVID-19 must include communication strategies at the forefront to reduce the risk of the emergence of new diseases and enhance efforts to control their spread and burden. Despite key themes emerging, what constitutes effective communication strategies for different people and contexts needs to be investigated further.
    Keywords COVID-19 infection ; globalization ; misinformation ; public health ; risk reduction
    Language English
    Dates of publication 2021-0603
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13061058
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Chemicals Constituents Isolated from Cultivate

    Taib, Mohamad Nurul Azmi Mohamad / Anuar, Nursyazwani / Hanafiah, Khayriyyah Mohd / Al-Shammary, Aeman Ali Kudayr / Saaid, Mardiana / Awang, Khalijah

    Tropical life sciences research

    2020  Volume 31, Issue 1, Page(s) 159–178

    Abstract: ... Alpinia ... ...

    Abstract Alpinia conchigera
    Language English
    Publishing date 2020-04-07
    Publishing country Malaysia
    Document type Journal Article
    ZDB-ID 2607038-8
    ISSN 2180-4249 ; 1985-3718
    ISSN (online) 2180-4249
    ISSN 1985-3718
    DOI 10.21315/tlsr2020.31.1.10
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Public knowledge, perception and communication behavior surrounding COVID-19 in Malaysia

    Mohd Hanafiah, Khayriyyah / Wan, Chang Da

    2020  

    Abstract: The COVID-19 pandemic is the first to occur in an age of hyperconnectivity. This paper presents results from an online anonymous survey conducted in Malay, English, and Chinese, during the first week of the Movement Control Order in Malaysia (n=1075), ... ...

    Abstract The COVID-19 pandemic is the first to occur in an age of hyperconnectivity. This paper presents results from an online anonymous survey conducted in Malay, English, and Chinese, during the first week of the Movement Control Order in Malaysia (n=1075), which aimed to examine public knowledge, perception and communication behavior in the Malaysian society in the face of a sudden outbreak and social distancing measures. Although the level of public knowledge, risk perception and positive communication behavior surrounding COVID-19 was high, a majority of respondents reported receiving a lot of questionable information. Multinomial logistic regression further identified that responses to different items varied significantly across respondent survey language, gender, age, education level and employment status.
    Keywords covid19
    Publisher SAGE Publications
    Publishing country us
    Document type Book ; Online
    DOI 10.31124/advance.12102816.v1
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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