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  1. Article: Development of Point-of-Care Biosensors for COVID-19.

    Choi, Jane Ru

    Frontiers in chemistry

    2020  Volume 8, Page(s) 517

    Abstract: Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. While conventional technologies such as quantitative real ...

    Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. While conventional technologies such as quantitative real time polymerase chain reaction (qRT-PCR) have been broadly used to detect COVID-19, they are time-consuming, labor-intensive and are unavailable in remote settings. Point-of-care (POC) biosensors, including chip-based and paper-based biosensors are typically low-cost and user-friendly, which offer tremendous potential for rapid medical diagnosis. This mini review article discusses the recent advances in POC biosensors for COVID-19. First, the development of POC biosensors which are made of polydimethylsiloxane (PDMS), papers, and other flexible materials such as textile, film, and carbon nanosheets are reviewed. The advantages of each biosensors along with the commercially available COVID-19 biosensors are highlighted. Lastly, the existing challenges and future perspectives of developing robust POC biosensors to rapidly identify and manage the spread of COVID-19 are briefly discussed.
    Keywords covid19
    Language English
    Publishing date 2020-05-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2020.00517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Advances in single cell technologies in immunology.

    Choi, Jane Ru

    BioTechniques

    2020  Volume 69, Issue 3, Page(s) 226–236

    Abstract: The immune system is composed of heterogeneous populations of immune cells that regulate physiological processes and protect organisms against diseases. Single cell technologies have been used to assess immune cell responses at the single cell level, ... ...

    Abstract The immune system is composed of heterogeneous populations of immune cells that regulate physiological processes and protect organisms against diseases. Single cell technologies have been used to assess immune cell responses at the single cell level, which are crucial for identifying the causes of diseases and elucidating underlying biological mechanisms to facilitate medical therapy. In the present review we first discuss the most recent advances in the development of single cell technologies to investigate cell signaling, cell-cell interactions and cell migration. Each technology's advantages and limitations and its applications in immunology are subsequently reviewed. The latest progress toward commercialization, the remaining challenges and future perspectives for single cell technologies in immunology are also briefly discussed.
    MeSH term(s) Allergy and Immunology/trends ; Cell Communication/genetics ; Cell Communication/immunology ; Cell Movement/genetics ; Humans ; Immune System/immunology ; Single-Cell Analysis/trends
    Language English
    Publishing date 2020-08-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 48453-2
    ISSN 1940-9818 ; 0736-6205
    ISSN (online) 1940-9818
    ISSN 0736-6205
    DOI 10.2144/btn-2020-0047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Current Status and Perspectives of Human Mesenchymal Stem Cell Therapy 2020.

    Choi, Jane Ru / Yong, Kar Wey / Nam, Hui Yin

    Stem cells international

    2022  Volume 2022, Page(s) 9801358

    Language English
    Publishing date 2022-02-11
    Publishing country United States
    Document type Editorial
    ZDB-ID 2573856-2
    ISSN 1687-9678 ; 1687-966X
    ISSN (online) 1687-9678
    ISSN 1687-966X
    DOI 10.1155/2022/9801358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Development of Point-of-Care Biosensors for COVID-19

    Choi, Jane Ru

    Frontiers in Chemistry

    2020  Volume 8

    Keywords General Chemistry ; covid19
    Publisher Frontiers Media SA
    Publishing country ch
    Document type Article ; Online
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2020.00517
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Development of Point-of-Care Biosensors for COVID-19

    Jane Ru Choi

    Frontiers in Chemistry, Vol

    2020  Volume 8

    Abstract: Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. While conventional technologies such as quantitative real ...

    Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. While conventional technologies such as quantitative real time polymerase chain reaction (qRT-PCR) have been broadly used to detect COVID-19, they are time-consuming, labor-intensive and are unavailable in remote settings. Point-of-care (POC) biosensors, including chip-based and paper-based biosensors are typically low-cost and user-friendly, which offer tremendous potential for rapid medical diagnosis. This mini review article discusses the recent advances in POC biosensors for COVID-19. First, the development of POC biosensors which are made of polydimethylsiloxane (PDMS), papers, and other flexible materials such as textile, film, and carbon nanosheets are reviewed. The advantages of each biosensors along with the commercially available COVID-19 biosensors are highlighted. Lastly, the existing challenges and future perspectives of developing robust POC biosensors to rapidly identify and manage the spread of COVID-19 are briefly discussed.
    Keywords POC biosensors ; PDMS ; paper ; flexible materials ; COVID-19 ; Chemistry ; QD1-999
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Editorial for the Special Issue on Point-of-Care Devices.

    Choi, Jane Ru / Yong, Kar Wey

    Micromachines

    2020  Volume 11, Issue 4

    Abstract: Point-of-care (POC) devices, such as paper- and chip-based devices enable the quick collection of patients' health information to improve healthcare [ ... ]. ...

    Abstract Point-of-care (POC) devices, such as paper- and chip-based devices enable the quick collection of patients' health information to improve healthcare [...].
    Language English
    Publishing date 2020-04-09
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi11040389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Development of Point-of-Care Biosensors for COVID-19

    Choi, Jane Ru

    Front. Chem.

    Abstract: Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. While conventional technologies such as quantitative real ...

    Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. While conventional technologies such as quantitative real time polymerase chain reaction (qRT-PCR) have been broadly used to detect COVID-19, they are time-consuming, labor-intensive and are unavailable in remote settings. Point-of-care (POC) biosensors, including chip-based and paper-based biosensors are typically low-cost and user-friendly, which offer tremendous potential for rapid medical diagnosis. This mini review article discusses the recent advances in POC biosensors for COVID-19. First, the development of POC biosensors which are made of polydimethylsiloxane (PDMS), papers, and other flexible materials such as textile, film, and carbon nanosheets are reviewed. The advantages of each biosensors along with the commercially available COVID-19 biosensors are highlighted. Lastly, the existing challenges and future perspectives of developing robust POC biosensors to rapidly identify and manage the spread of COVID-19 are briefly discussed.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #613159
    Database COVID19

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  8. Article ; Online: Current Status and Perspectives of Human Mesenchymal Stem Cell Therapy 2020

    Jane Ru Choi / Kar Wey Yong / Hui Yin Nam

    Stem Cells International, Vol

    2022  Volume 2022

    Keywords Internal medicine ; RC31-1245
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Editorial: Advances in Nucleic Acid-Based Biosensors and Imaging.

    Choi, Jane Ru / Somasundrum, Mithran / Shiddiky, Muhammad J A / Surareungchai, Werasak / Hu, Yufang / Qing, Zhihe

    Frontiers in chemistry

    2022  Volume 10, Page(s) 925082

    Language English
    Publishing date 2022-05-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2022.925082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Epidemiology of Pathogenic Retroviruses and Domestic Cat Hepadnavirus in Community and Client-Owned Cats in Hong Kong.

    Beatty, Julia A / Choi, Yan Ru / Nekouei, Omid / Woodhouse, Fiona M / Gray, Jane J / Hofmann-Lehmann, Regina / Barrs, Vanessa R

    Viruses

    2024  Volume 16, Issue 2

    Abstract: Understanding the local epidemiology of feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) in Hong Kong will inform retrovirus prevention strategies. Domestic cat hepadnavirus (DCH), a novel hepatitis-B-like virus, is commonly detected ...

    Abstract Understanding the local epidemiology of feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) in Hong Kong will inform retrovirus prevention strategies. Domestic cat hepadnavirus (DCH), a novel hepatitis-B-like virus, is commonly detected among client-owned cats in Hong Kong, but community cats have not been studied. The aims of this study were to investigate the frequency and potential risk factors for (i) FeLV and FIV among community and client-owned cats and (ii) perform molecular detection of DCH among community cats in Hong Kong. Blood samples from 713 cats were obtained from client-owned (n = 415, residual diagnostic) and community cats (n = 298, at trap-neuter-return). Point-of-care (POC) testing for FeLV antigen and feline immunodeficiency virus (FIV) anti-p15 and p24 antibodies was performed. FeLV-positive samples were progressed to p27 sandwich enzyme-linked immunosorbent assay. Whole blood DNA was tested with qPCRs for FeLV U3 and gag, and nested PCRs where additional information was required. DCH qPCR was performed on a subset of community cats (n = 193). A single, regressive, FeLV infection was detected in a client-owned cat (1/415 FeLV U3 qPCR positive, 0.2%, 95% CI 0.0-1.3%). Five/415 client-owned cats tested presumably false FeLV-antigen positive (qPCR negative). No markers of FeLV infection were detected in community cats (0/298; 0%). FIV seroprevalence was much higher in community cats (46/298, 15.4%) than in client-owned cats (13/415, 3.1%) (
    MeSH term(s) Humans ; Animals ; Cats ; Feline Acquired Immunodeficiency Syndrome ; Retroviridae/genetics ; Hepadnaviridae/genetics ; Seroepidemiologic Studies ; Hong Kong/epidemiology ; Immunodeficiency Virus, Feline/genetics ; Leukemia, Feline ; Leukemia Virus, Feline/genetics ; Antibodies, Viral ; DNA ; Cat Diseases/diagnosis ; Cat Diseases/epidemiology
    Chemical Substances Antibodies, Viral ; DNA (9007-49-2)
    Language English
    Publishing date 2024-01-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16020167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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