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Book ; Online ; E-Book: Medicinal Plants Used in Traditional Persian Medicine

Schulz, Hartwig / Emami, Seyed Ahmad / Nadjafi, Farsad / Abadi, Mamak Hashemi Habib / Akabery, Maryam / Askari, Seyyed Ahmad / Askari, Sayyedeh Fatemeh / Ayati, Zahra / Azad, Sajad / Badr, Parmis

2023

Abstract: Traditional Persian Medicine (TPM) is one of the most ancient medical doctrines, and is well-documented in terms of information about diseases, diagnoses and treatments, especially by the application of medicinal plants. This book presents the key ... ...

Abstract	Traditional Persian Medicine (TPM) is one of the most ancient medical doctrines, and is well-documented in terms of information about diseases, diagnoses and treatments, especially by the application of medicinal plants. This book presents the key medicinal plants used in TPM.
Subject code	615.3/210955
Language	English
Size	1 online resource (636 pages)
Edition	1st ed.
Publisher	CAB International
Publishing place	Oxford
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	1-80062-167-1 ; 1-80062-166-3 ; 9781800621657 ; 978-1-80062-167-1 ; 978-1-80062-166-4 ; 1800621655
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: The effects of eight weeks of aerobic training with vitamin C on the expression pathway of antioxidants in the hippocampus tissue of TMT induced Alzheimer's disease rats.

Hashemi, Seyed Ahmad / Ghadimi, Zahra / Ghaedi, Hadi / Hashemi, Ayoub

Brain research

2023 Volume 1822, Page(s) 148645

Abstract: Introduction: Alzheimer's disease (AD) is one of the most common neurological disorders and, researchers believe that the impairment of oxidant-antioxidant system plays an important role in its progression. The PI3K/NRF2 pathway has particular ... ...

Abstract	Introduction: Alzheimer's disease (AD) is one of the most common neurological disorders and, researchers believe that the impairment of oxidant-antioxidant system plays an important role in its progression. The PI3K/NRF2 pathway has particular importance in increasing the expression of antioxidants. Thus present study aimed to investigate the effect of eight weeks of aerobic training (AT) with vitamin C (VC) on the expression pathway of antioxidants in the hippocampus tissue of trimethyltin chloride (TMT) induced Alzheimer's Disease Rats. Methods: In this experimental study, 28 male Sprague-Dawley rats (age 14-16 months, weight 270-320 g) were injected 10 mg/kg TMT and were divided into (1) TMT (n = 7), (2) TMT + VC (n = 7), (3) TMT + AT (n = 7) and (4) TMT + VC + AT (n = 7) groups. Also, 7 healthy rats without any intervention selected as healthy control (HC) group to investigate the effects of TMT on research variables. Groups 3 and 4 ran on the treadmill for eight weeks, for 15-48 min at a speed of 10-24 m/min. Also, groups 2 and 4 received 4 mg/kg VC orally. To measure PI3K, Nrf2, SOD and catalase in the hippocampus tissue of rats, ELISA method were used. To analyze the data, one-way analysis of variance with Tukey's post- hoc tests were used (P ≤ 0.05). Results: The hippocampal values of Nrf2 and SOD in TMT + VC, TMT + AT and TMT + VC + AT groups were higher than TMT group (P = 0.001). Catalase in TMT + AT and TMT + VC + AT groups was higher than TMT group (P = 0.001). Also, catalase and PI3K were higher in the TMT + VC + AT group than the TMT + VC group (P = 0.05). PI3K levels of TMT + VC + AT group were higher than TMT + AT group (P = 0.02). Conclusion: It seems that AT and VC, both alone and in combination, play a role in improving the transcription pathway of antioxidants in the hippocampus tissue of TMT induced Alzheimer's disease Rats. Therefore, the combination of these two interventions is suggested to improve the antioxidant system.
MeSH term(s)	Rats ; Male ; Animals ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Ascorbic Acid/pharmacology ; Ascorbic Acid/metabolism ; Alzheimer Disease/chemically induced ; Alzheimer Disease/metabolism ; Catalase/metabolism ; NF-E2-Related Factor 2/metabolism ; Rats, Sprague-Dawley ; Oxidative Stress ; Hippocampus/metabolism ; Superoxide Dismutase/metabolism ; Phosphatidylinositol 3-Kinases/metabolism
Chemical Substances	Antioxidants ; Ascorbic Acid (PQ6CK8PD0R) ; Catalase (EC 1.11.1.6) ; NF-E2-Related Factor 2 ; Superoxide Dismutase (EC 1.15.1.1) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-)
Language	English
Publishing date	2023-10-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1200-2
ISSN	1872-6240 ; 0006-8993
ISSN (online)	1872-6240
ISSN	0006-8993
DOI	10.1016/j.brainres.2023.148645
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Article ; Online: Kidney stones and dietary intake in adults: a population-based study in southwest Iran.

Cheraghian, Bahman / Meysam, Alipour / Hashemi, Seyed Jalal / Hosseini, Seyed Ahmad / Malehi, Amal Saki / Khazaeli, Dinyar / Rahimi, Zahra

BMC public health

2024 Volume 24, Issue 1, Page(s) 955

Abstract: Background: The prevalence of kidney stones is on the rise globally. Several risk factors, including lifestyle, contribute to the formation of kidney stones. Nevertheless, there is a contentious debate about the relationship between diet and kidney ... ...

Abstract	Background: The prevalence of kidney stones is on the rise globally. Several risk factors, including lifestyle, contribute to the formation of kidney stones. Nevertheless, there is a contentious debate about the relationship between diet and kidney stones. Therefore, our study aimed to assess the relationship between macronutrients and micronutrients and the formation of kidney stones. Methods: This population-based cross-sectional study was conducted in the baseline phase of the Hoveyzeh Cohort Study, focusing on adults aged 35-70 in southwest Iran. The information on demographic characteristics, anthropometrics, kidney stone history, and food frequency was collected. Chi-square and t-tests were utilized to assess the relationship between categorical and numerical variables with kidney stones. The ANCOVA and logistic regression models were used to evaluate the relationships while controlling for confounding factors. Results: Among 10,009 participants, the overall prevalence of kidney stones was 18.77% (95% CI: 17.99-19.53). A higher intake of carbohydrates [OR = 1.02 (95% CI:1.002-1.03), p = 0.026] and copper [OR = 1.04 (95% CI:1.01-1.09), p = 0.025] were found to be associated with kidney stones. No associations were found between the other assessed macronutrients or micronutrients and kidney stones (p-tvalues > 0.05). Conclusion: Our study's findings indicate a correlation between diet and the formation of kidney stones. However, the relationship between dietary factors and kidney stones is complex, and further research is needed.
MeSH term(s)	Adult ; Humans ; Cohort Studies ; Cross-Sectional Studies ; Iran/epidemiology ; Risk Factors ; Kidney Calculi/epidemiology ; Kidney Calculi/etiology ; Eating ; Micronutrients
Chemical Substances	Micronutrients
Language	English
Publishing date	2024-04-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-024-18393-1
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Article ; Online: The dietary patterns derived by reduced-rank regression in association with Framingham risk score and lower DASH score in Hoveyzeh cohort study

Marzieh Shoja / Fatemeh Borazjani / Kambiz Ahmadi Angali / Seyed Ahmad Hosseini / Seyed Jalal Hashemi

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 14

Abstract: Abstract The relationship between dietary patterns (DPs) and cardiovascular disease (CVD) has been the subject of much research, but given the significance of this disease, studying the factors affecting it through different methodological considerations ...

Abstract	Abstract The relationship between dietary patterns (DPs) and cardiovascular disease (CVD) has been the subject of much research, but given the significance of this disease, studying the factors affecting it through different methodological considerations is of utmost importance. This study aimed to investigate the association between the four dietary patterns (DPs) derived from reduced-rank regression (RRR) and the risk of CVD predicted by the Framingham Risk Score (FRS) in the Arab residence of Khuzestan, Iran. Furthermore, the predefined Dietary Approaches to Stop Hypertension (DASH) would be used as a comparative model to assess the validity of the extracted DPs. In this cross-sectional study, 5799 individuals aged 35–70 without a CVD diagnosis were selected among the participants of the Hoveyzeh cohort study (HCS). The Risk of CVD was assessed using the FRS model. A semi-quantitative food frequency questionnaire evaluated dietary intake. Four DPs were derived using RRR with 28 food groups as predictors and total protein (g/d), fiber(g/d), fat(g/d), and magnesium intake (mg/d) as response variables. Multinomial and binary logistic regression were used to assess the relationship of DPs with intermediate (10–20%) and high (> 20%) levels of FRS and lower DASH scores (< 4.5), respectively. Four primary DPs were derived, which explained 89.10 of the total explained variance in participants’ dietary intake. Multinomial regression was applied between FRS (10–20%) and (> 20%) across quartiles of four identified DPs. After adjustment for potential confounders, higher tendency to 1st and 2nd DPs in Model 1, OR = 4.67 (95% CI 3.65; 6.01), OR = 1.42 (95% CI 1.13; 1.79) were presented accordingly. The 1st DP, characterized by higher intake of refined grains and lower intake of vegetables oil, sugar, mayonnaise and artificial juices, the 2nd DP characterized by higher intake of hydrogenated fat and lower consumption of tomato sauce and soft drink was associated with greater odds of CVD with the intermediate level ...
Keywords	Medicine ; R ; Science ; Q
Subject code	910
Language	English
Publishing date	2023-07-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The dietary patterns derived by reduced-rank regression in association with Framingham risk score and lower DASH score in Hoveyzeh cohort study.

Shoja, Marzieh / Borazjani, Fatemeh / Ahmadi Angali, Kambiz / Hosseini, Seyed Ahmad / Hashemi, Seyed Jalal

Scientific reports

2023 Volume 13, Issue 1, Page(s) 11093

Abstract: The relationship between dietary patterns (DPs) and cardiovascular disease (CVD) has been the subject of much research, but given the significance of this disease, studying the factors affecting it through different methodological considerations is of ... ...

Abstract	The relationship between dietary patterns (DPs) and cardiovascular disease (CVD) has been the subject of much research, but given the significance of this disease, studying the factors affecting it through different methodological considerations is of utmost importance. This study aimed to investigate the association between the four dietary patterns (DPs) derived from reduced-rank regression (RRR) and the risk of CVD predicted by the Framingham Risk Score (FRS) in the Arab residence of Khuzestan, Iran. Furthermore, the predefined Dietary Approaches to Stop Hypertension (DASH) would be used as a comparative model to assess the validity of the extracted DPs. In this cross-sectional study, 5799 individuals aged 35-70 without a CVD diagnosis were selected among the participants of the Hoveyzeh cohort study (HCS). The Risk of CVD was assessed using the FRS model. A semi-quantitative food frequency questionnaire evaluated dietary intake. Four DPs were derived using RRR with 28 food groups as predictors and total protein (g/d), fiber(g/d), fat(g/d), and magnesium intake (mg/d) as response variables. Multinomial and binary logistic regression were used to assess the relationship of DPs with intermediate (10-20%) and high (> 20%) levels of FRS and lower DASH scores (< 4.5), respectively. Four primary DPs were derived, which explained 89.10 of the total explained variance in participants' dietary intake. Multinomial regression was applied between FRS (10-20%) and (> 20%) across quartiles of four identified DPs. After adjustment for potential confounders, higher tendency to 1st and 2nd DPs in Model 1, OR = 4.67 (95% CI 3.65; 6.01), OR = 1.42 (95% CI 1.13; 1.79) were presented accordingly. The 1st DP, characterized by higher intake of refined grains and lower intake of vegetables oil, sugar, mayonnaise and artificial juices, the 2nd DP characterized by higher intake of hydrogenated fat and lower consumption of tomato sauce and soft drink was associated with greater odds of CVD with the intermediate level of FRS. However, higher adherence to the 3rd DP, characterized by higher intake of fruits, vegetables and legumes and lower intake of fish, egg, red meat, processed meat, mayonnaise, sugar and artificial juices, the 4th DP characterized by higher intake of coffee, nuts and lower intake of sugar, mayonnaise and artificial juices was associated with a lower risk of FRS. Moreover, lower DASH score considered in binary logistic regression across quartiles of four identified dietary patterns. 1st and 2nd DPs were directly related to lower DASH scores, while 3rd and 4th DPs had high comparability with the DASH diet and inversely contributed to the lower DASH score. Total DASH score was significantly correlated to four derived DPs. Our findings confirm the current knowledge regarding the beneficial effects of healthy plant-based DPs and the avoidance of high-fat and processed foods to prevent CVD.
MeSH term(s)	Dietary Approaches To Stop Hypertension ; Cohort Studies ; Cross-Sectional Studies ; Risk Factors ; Diet ; Vegetables ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Cardiovascular Diseases/metabolism ; Sugars
Chemical Substances	Sugars
Language	English
Publishing date	2023-07-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-37809-3
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Article ; Online: The effect of using the reverse class approach on learning the experimental sciences of elementary school students

Khalil Forootan / Seyed Ahmad Hashemi / Abbas Qaltash / Ali Asghar Mashinchi

مجله علوم روانشناختی, Vol 21, Iss 119, Pp 2285-

2023 Volume 2302

Abstract: Background: Traditional teaching methods have faced many shortcomings that the technical advances and requirements of today's world, has necessitated the need for a new approach to education that the need for a mobile education approach is felt. Aims: ... ...

Abstract	Background: Traditional teaching methods have faced many shortcomings that the technical advances and requirements of today's world, has necessitated the need for a new approach to education that the need for a mobile education approach is felt. Aims: The aim of this study was to determine the effect of education using reverse learning on the learning of sixth grade elementary students in the course of experimental sciences. Methods: In terms of purpose of this research as applied research and in terms of implementation and data collection method, the quasi-experimental method of pretest-posttest design with control group was used. The statistical population of the present study included all 3,000 elementary school students in Lamerd city. Sampling method in this study was available which included 60 students and were selected through available sampling. Thus, two classes of 30 people were selected from the sixth grade elementary schools of Lamerd city. In order to collect information, a researcher-made learning test of science course was used. Univariate analysis of covariance (ANCOVA) was used to infer the hypotheses. Results: The results of data analysis showed that reverse learning is effective on students 'learning (P <0.01). Therefore, it can be concluded that education using reverse learning is effective and has increased students' learning. Conclusion: Considering the many effects of using the reverse class method, which has been emphasized in most studies, it is necessary to move scientifically and with careful and codified planning towards the rational use of this method in education.
Keywords	reverse learning ; science ; learning ; memorization ; students ; Psychology ; BF1-990
Subject code	370
Language	Persian
Publishing date	2023-01-01T00:00:00Z
Publisher	Dr. Mahmoud Mansour publication
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spectrum of Beta-Thalassemia Mutations in Potential Carriers with Microcytic Hypochromic Anemia from Mazandaran and Golestan, Northern Provinces of Iran.

Mousavi, Seyed Saeed / Karami, Hossein / Tamadoni, Ahmad / Mahmoudi, Hassan / Shekarriz, Ramin / Siami, Rita / Hashemi-Soteh, Mohammad Bagher

BioMed research international

2024 Volume 2024, Page(s) 8664803

Abstract: Introduction: β: Methods: 5425 microcytic and hypochromic individuals were investigated from Mazandaran and Golestan provinces. From these, 1323 beta carrier or affected individuals were selected where 938 persons were from Mazandaran and 385 people ... ...

Abstract	Introduction: β Methods: 5425 microcytic and hypochromic individuals were investigated from Mazandaran and Golestan provinces. From these, 1323 beta carrier or affected individuals were selected where 938 persons were from Mazandaran and 385 people were from Golestan province, respectively. Result: 53 different mutations were identified, IVSII-1 (G>A) was the most common (59.14%) followed by Cd 22/23/24 (-7 bp) (5.34%), Cd 8 (-AA) (4.93%), Cd30 (G>A) (4.00%), and IVSI-5 (G>C) (3.70%) with a total of 77.11% in Mazandaran Province, respectively. In Golestan Province, IVSI-5 (G>C) was the most frequent (44.62%) followed by IVSII-1 (G>A) (27.18%), Cd 15 (TGG>TAG) (4.36%), Fr 8/9(+G) (3.85%), and Cd 8(-AA) (2.05%) with a total of 82.06%, respectively. From the 53 different mutations, 22 numbers have been observed in both provinces. Two deletions of the beta gene named Sicilian and Asian-Indian have been detected in Mazandaran with a frequency of 0.72% each. Conclusion: The 53 different mutations identified in this study were the most ever reported mutations in the country. Due to diversity of different ethnic groups, there are many varieties of mutation in beta globin gene in Iran. It could be assumed that both founder effect and natural selection caused by migration from neighboring areas have complemented each other to produce the high frequency of unique alleles within each region.
MeSH term(s)	Humans ; beta-Thalassemia/genetics ; Iran ; Cadmium ; Mutation ; Anemia, Hypochromic
Chemical Substances	Cadmium (00BH33GNGH)
Language	English
Publishing date	2024-01-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2024/8664803
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Article ; Online: Relationship between healthy eating index and sarcopenia in elderly people.

Ghoreishy, Seyed Mojtaba / Koujan, Soraya Ebrahimpour / Hashemi, Rezvan / Heshmat, Ramin / Motlagh, Ahmadreza Dorosty / Esmaillzadeh, Ahmad

BMC geriatrics

2023 Volume 23, Issue 1, Page(s) 25

Abstract: Background: Data on the association of Alternative Healthy Eating Index-2010 (AHEI-2010) with sarcopenia are scarce. We aimed to evaluate the association between adherence to AHEI-2010 and sarcopenia and its components including low muscle mass, low ... ...

Abstract	Background: Data on the association of Alternative Healthy Eating Index-2010 (AHEI-2010) with sarcopenia are scarce. We aimed to evaluate the association between adherence to AHEI-2010 and sarcopenia and its components including low muscle mass, low muscle strength, and low muscle performance among elderly people. Methods: In this cross-sectional study, which was conducted on 300 older people (150 men and 150 women) aged ≥55 years. Dietary information was done using a valid 117-item food frequency questionnaire (FFQ). To construct AHEI-2010 score, earlier studies were used. Sarcopenia and its components were described based on both former and new European Working Group on Sarcopenia in Older People (EWGSOP) guidelines. Results: We found no significant association between AHEI-2010 score and odds of EWGSOP2-sarcopenia, either before (OR for the highest vs. lowest tertiles: 0.55; 95% CI: 0.19, 1.55) or after (OR: 0.44; 95% CI: 0.14, 1.34) adjustment for confounders. In gender-stratified analyses, we found a significant protective association between adherence to the AHEI-2010 score and odds of EWGSOP2-sarcopenia among women after controlling for confounders (0.20; 95%CI: 0.04, 0.91). Conclusions: In conclusion, healthy eating was inversely associated with odds of sarcopenia among women, but not in men. Further studies with a large sample size and prospective design are needed to examine this association.
MeSH term(s)	Male ; Aged ; Humans ; Female ; Sarcopenia/diagnosis ; Sarcopenia/epidemiology ; Diet, Healthy ; Cross-Sectional Studies ; Muscle Strength/physiology ; Diet ; Hand Strength/physiology
Language	English
Publishing date	2023-01-14
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-023-03734-3
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Article ; Online: The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model.

Khosrojerdi, Arezou / Soudi, Sara / Hosseini, Ahmad Zavaran / Khaligh, Sahar Ghaffari / Hashemi, Seyed Mahmoud

Life sciences

2023 Volume 326, Page(s) 121813

Abstract: Aim Sepsis is a medical emergency with no definitive treatment. Animal experiments have confirmed the therapeutic characteristics of exosomes in reducing inflammation and tissue damage. The study investigates the effect of MSC and hepatocyte-derived ... ...

Abstract	Aim Sepsis is a medical emergency with no definitive treatment. Animal experiments have confirmed the therapeutic characteristics of exosomes in reducing inflammation and tissue damage. The study investigates the effect of MSC and hepatocyte-derived exosomes along with imipenem in controlling systemic and local (liver) inflammation in a mouse model of sepsis. Main methods: To induce sepsis in C57BL/6 mice, the Cecal Ligation and Puncture (CLP) model was used. The mice were given various treatments, including imipenem, MSC-derived exosomes, hepatocyte-derived exosomes, and a mixture of exosomes. Blood and liver samples were collected and analyzed for cell blood count, liver enzymes, NO levels, cytokine concentrations, and bacterial presence. The percentages of TCD3 + CD4+/CD8+ and Treg in the spleen and mesenteric lymph nodes were also assessed using flow cytometry. The pathological changes were assessed in the liver, lung, and heart tissues. In addition, the cytokine content of exosomes was measured by ELISA. Key findings: Our results demonstrated that MSC-derived exosomes+imipenem could control systemic and local inflammation and increase the TCD4+ and Treg populations. Hepatocyte-derived exosomes+imipenem reduced inflammation in the liver and increased the TCD8+ and Treg populations. The mixture of exosomes+imipenem had the best function in reducing inflammation, maintaining all T lymphocyte populations, reducing liver damage, and ultimately increasing the survival rate. Significance: The mixture of exosomes derived from MSCs and hepatocytes, along with imipenem, in the inflammatory phase of sepsis could be a promising therapeutic strategy in sepsis treatment.
MeSH term(s)	Mice ; Animals ; Imipenem/pharmacology ; Exosomes/pathology ; Mice, Inbred C57BL ; Hepatocytes/pathology ; Cytokines ; Liver/pathology ; Inflammation/drug therapy ; Sepsis/pathology ; Mesenchymal Stem Cells/pathology
Chemical Substances	Imipenem (71OTZ9ZE0A) ; Cytokines
Language	English
Publishing date	2023-05-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2023.121813
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Article ; Online: Association between oral contraceptives with lipid profile: results from Hoveyzeh cohort study (HCS).

Hashemi, Seyed Jalal / Khezri, Rozhan / Saki, Nader / Nasehi, Nahal / Hosseini, Seyed Ahmad / Harizi, Mahmood / Rahimi, Zahra

BMC women's health

2023 Volume 23, Issue 1, Page(s) 552

Abstract: Background: Oral contraceptives (OCs) affect lipid metabolism, which can cause hyperlipidemia, a risk factor for cardiovascular diseases. The study was designed to evaluate the possible changes in lipid profile due to using OCs.: Methods: A cross- ... ...

Abstract	Background: Oral contraceptives (OCs) affect lipid metabolism, which can cause hyperlipidemia, a risk factor for cardiovascular diseases. The study was designed to evaluate the possible changes in lipid profile due to using OCs. Methods: A cross-sectional study was conducted from April 2016 to August 2018 among women from the baseline phase Hoveyzeh cohort study (HCS). Sociodemographic data, anthropometric measurements, physical activity, and biochemical blood tests were measured for every participant. Multiple logistic regression was used to adjust the potential confounders. Results: Among 2272 participants, 1549 women were OC users, and 723 women were non-user OCs. The mean lipid profile levels were higher in OC users than in non-user OCs. Odds of abnormal Total cholesterol (TC) in OC users were significantly higher than those of non-users OCs [OR = 1.29 (95% CI;1.05 to 1.58)]. Also, the Odds of abnormal low-density lipoprotein (LDL) in OC users was 12% higher than in non-user OCs. However, no significant relationship between abnormal LDL with Oral Contraceptive Pills (OCPs) was observed. Conclusions: The mean lipid profile was higher in OC users compared to non-user OCs. This finding highlights the need for public health strategies to prevent and detect hyperlipidemia in user OCs.
MeSH term(s)	Humans ; Female ; Contraceptives, Oral ; Cohort Studies ; Cross-Sectional Studies ; Lipoproteins, LDL ; Hyperlipidemias/epidemiology
Chemical Substances	Contraceptives, Oral ; Lipoproteins, LDL
Language	English
Publishing date	2023-10-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2050444-5
ISSN	1472-6874 ; 1472-6874
ISSN (online)	1472-6874
ISSN	1472-6874
DOI	10.1186/s12905-023-02703-7
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