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  1. Article ; Online: Multilevel Micronanoscale Texture Effects on Fly Wing Membrane-Water Droplet Interaction.

    Zeng, Gaofei / Wang, Zhou / Tian, Guangjian / Xia, Lu / Zhang, Yi

    ACS applied materials & interfaces

    2024  Volume 16, Issue 13, Page(s) 17007–17015

    Abstract: The wettable surface or nonwettable surface that is derived from a multilevel micronanoscale structure is abundant in nature and biomimetic commodities. Those hoverflies with the seta-coated wing membrane detached from impacting free-falling raindrops ... ...

    Abstract The wettable surface or nonwettable surface that is derived from a multilevel micronanoscale structure is abundant in nature and biomimetic commodities. Those hoverflies with the seta-coated wing membrane detached from impacting free-falling raindrops were observed in static states. A hoverfly wing membrane with well-ordered setae was identified as a robust nonwettable surface, and the static water contact angle θ on the wing membrane at the microscopic scale is 136.84 ± 0.98°. Hoverfly wing membrane-water droplet interaction with the actual truth and the theoretical models was discussed and indicated that the theoretical calculation might not state the actual situation, arising from the membrane or seta-drop-bubble interaction and those multilevel micronanoscale structure characteristics on the wing membrane. Detailed investigation on nonwettable surface-wettable surface transformation with surface CaCO
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.4c00275
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  2. Article: Transcriptomic and metabolic analysis unveils the mechanism behind leaf color development in

    Tian, Xiaoming / Xiang, Guangfeng / Lv, Hao / Zhu, Lu / Peng, Jing / Li, Gaofei / Mou, Cun

    Frontiers in molecular biosciences

    2024  Volume 11, Page(s) 1343123

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2024.1343123
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  3. Article ; Online: Transition-Metal-Free Cascade Approach for the Synthesis of Functionalized Biaryls by S

    Xu, Gaofei / Han, Zongtao / Guo, Lirong / Lu, Haifeng / Gao, Hongyin

    The Journal of organic chemistry

    2022  Volume 87, Issue 15, Page(s) 10449–10453

    Abstract: We report a transition-metal-free protocol for the synthesis of functionalized biaryls through nucleophilic aromatic substitution ( ... ...

    Abstract We report a transition-metal-free protocol for the synthesis of functionalized biaryls through nucleophilic aromatic substitution (S
    Language English
    Publishing date 2022-07-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.2c00990
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    Zs.A 4473: Show issues Location:
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  4. Article ; Online: Biomineralization and biotechnological applications of bacterial magnetosomes.

    Ying, Gaofei / Zhang, Guojing / Yang, Jiani / Hao, Ziyu / Xing, Weijia / Lu, Dong / Zhang, Shuang / Yan, Lei

    Colloids and surfaces. B, Biointerfaces

    2022  Volume 216, Page(s) 112556

    Abstract: Magnetosomes intracellularly biomineralized by Magnetotactic bacteria (MTB) are membrane-enveloped nanoparticles of the magnetic minerals magnetite ( ... ...

    Abstract Magnetosomes intracellularly biomineralized by Magnetotactic bacteria (MTB) are membrane-enveloped nanoparticles of the magnetic minerals magnetite (Fe
    MeSH term(s) Bacteria ; Bacterial Proteins ; Biomineralization ; Ferrosoferric Oxide ; Gram-Negative Bacteria ; Iron ; Magnetosomes
    Chemical Substances Bacterial Proteins ; Iron (E1UOL152H7) ; Ferrosoferric Oxide (XM0M87F357)
    Language English
    Publishing date 2022-05-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1500523-9
    ISSN 1873-4367 ; 0927-7765
    ISSN (online) 1873-4367
    ISSN 0927-7765
    DOI 10.1016/j.colsurfb.2022.112556
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  5. Article ; Online: The mechanism and therapy of aortic aneurysms

    Jianing Gao / Huanhuan Cao / Gaofei Hu / Yufei Wu / Yangkai Xu / Hongtu Cui / Hong S. Lu / Lemin Zheng

    Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-

    2023  Volume 20

    Abstract: Abstract Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally asymptomatic, it poses a significant threat to human life due to a high risk of rupture. Because of its strong concealment, it is difficult to ... ...

    Abstract Abstract Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally asymptomatic, it poses a significant threat to human life due to a high risk of rupture. Because of its strong concealment, it is difficult to diagnose the disease in the early stage. At present, there are no effective drugs for the treatment of aneurysms. Surgical intervention and endovascular treatment are the only therapies. Although current studies have discovered that inflammatory responses as well as the production and activation of various proteases promote aortic aneurysm, the specific mechanisms remain unclear. Researchers are further exploring the pathogenesis of aneurysms to find new targets for diagnosis and treatment. To better understand aortic aneurysm, this review elaborates on the discovery history of aortic aneurysm, main classification and clinical manifestations, related molecular mechanisms, clinical cohort studies and animal models, with the ultimate goal of providing insights into the treatment of this devastating disease. The underlying problem with aneurysm disease is weakening of the aortic wall, leading to progressive dilation. If not treated in time, the aortic aneurysm eventually ruptures. An aortic aneurysm is a local enlargement of an artery caused by a weakening of the aortic wall. The disease is usually asymptomatic but leads to high mortality due to the risk of artery rupture.
    Keywords Medicine ; R ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Gasless submental-transoral combined approach endoscopic thyroidectomy: a new surgical technique.

    Jiang, Jinxi / He, Gaofei / Chu, Junjie / Li, Jianbo / Lu, Xiaoxiao / Jiang, Xianfeng / Xie, Lei / Gao, Li / Zhang, Deguang

    Frontiers in oncology

    2023  Volume 13, Page(s) 1115927

    Abstract: Background: The development of transoral endoscopic vestibular approach thyroidectomy (TOETVA) has been limited by inherent defects, such as mental nerve injury and carbon dioxide (CO: Methods: We reviewed 75 patients who successfully underwent ... ...

    Abstract Background: The development of transoral endoscopic vestibular approach thyroidectomy (TOETVA) has been limited by inherent defects, such as mental nerve injury and carbon dioxide (CO
    Methods: We reviewed 75 patients who successfully underwent gasless STET using novel instruments at our institution from November 2020 to November 2021. A main incision of approximately 2 cm was made in the natural submental crease line and then combined with two vestibule incisions to complete the procedure. Demographic data, surgical technique and perioperative outcomes were retrospectively recorded.
    Results: Thirteen male and sixty-two female patients with a mean age of 34.0 ± 8.1 years were enrolled in this study. Sixty-eight patients had papillary thyroid carcinomas and seven had benign nodules. We successfully performed all gasless STET without conversion to open surgery. The average postoperative hospital stay was 4.2 ± 1.8 days. One transient recurrent laryngeal nerve injury and two transient hypoparathyroidisms were observed. Three patients complained of slight lower lip numbness on the first postoperative day. One case of lymphatic fistula, subcutaneous effusion, and incision swelling occurred each, all of which were conservatively cured. One patient developed a recurrence six months after surgery.
    Conclusions: Gasless STET using our own designed suspension system is technically safe and feasible with reasonable operative and oncologic results.
    Language English
    Publishing date 2023-05-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1115927
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  7. Article ; Online: The mechanism and therapy of aortic aneurysms.

    Gao, Jianing / Cao, Huanhuan / Hu, Gaofei / Wu, Yufei / Xu, Yangkai / Cui, Hongtu / Lu, Hong S / Zheng, Lemin

    Signal transduction and targeted therapy

    2023  Volume 8, Issue 1, Page(s) 55

    Abstract: Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally asymptomatic, it poses a significant threat to human life due to a high risk of rupture. Because of its strong concealment, it is difficult to diagnose the ... ...

    Abstract Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally asymptomatic, it poses a significant threat to human life due to a high risk of rupture. Because of its strong concealment, it is difficult to diagnose the disease in the early stage. At present, there are no effective drugs for the treatment of aneurysms. Surgical intervention and endovascular treatment are the only therapies. Although current studies have discovered that inflammatory responses as well as the production and activation of various proteases promote aortic aneurysm, the specific mechanisms remain unclear. Researchers are further exploring the pathogenesis of aneurysms to find new targets for diagnosis and treatment. To better understand aortic aneurysm, this review elaborates on the discovery history of aortic aneurysm, main classification and clinical manifestations, related molecular mechanisms, clinical cohort studies and animal models, with the ultimate goal of providing insights into the treatment of this devastating disease. The underlying problem with aneurysm disease is weakening of the aortic wall, leading to progressive dilation. If not treated in time, the aortic aneurysm eventually ruptures. An aortic aneurysm is a local enlargement of an artery caused by a weakening of the aortic wall. The disease is usually asymptomatic but leads to high mortality due to the risk of artery rupture.
    MeSH term(s) Animals ; Humans ; Aortic Aneurysm, Abdominal/surgery ; Aortic Rupture/genetics ; Aortic Rupture/therapy ; Cohort Studies
    Language English
    Publishing date 2023-02-03
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2886872-9
    ISSN 2059-3635 ; 2095-9907
    ISSN (online) 2059-3635
    ISSN 2095-9907
    DOI 10.1038/s41392-023-01325-7
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  8. Article ; Online: Novel suspension system for gasless transoral vestibular thyroidectomy.

    Jiang, Jinxi / He, Gaofei / Chu, Junjie / Li, Jianbo / Lu, Xiaoxiao / Zhang, Deguang

    Surgical endoscopy

    2022  Volume 37, Issue 2, Page(s) 1070–1076

    Abstract: Background: The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is receiving increased attention, frequently due to growing requirements for cosmetic incisions. Here, we report our initial experience and discuss the safety and efficacy ... ...

    Abstract Background: The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is receiving increased attention, frequently due to growing requirements for cosmetic incisions. Here, we report our initial experience and discuss the safety and efficacy of the innovative surgical working space suspension system for gasless TOETVA.
    Methods: We retrospectively analyzed 75 consecutive patients for whom gasless TOETVA with our novel working space suspension system was used. This suspension system included self-developed retractors, a sterile bandage, and an anesthesia stand. We also improved some main surgical instruments in gasless TOETVA.
    Results: The study included 75 patients who successfully underwent thyroidectomy and central neck dissection via gasless TOETVA. The mean operating time was 143.27 ± 34.60 min. The mean number of retrieved lymph nodes was 8.00 ± 5.39. Conversion to open surgery did not occur, nor did patients exhibit serious postoperative complications. Postoperative complications included 4 cases of transient recurrent laryngeal nerve (RLN) palsy, 9 of transient hypoparathyroidism, and 3 of transient mental nerve injury. One patient with subcutaneous fluid after surgery recovered after aspiration. Another patient with submental minor perforation recovered well after suturing. There was no evidence of specific complications related to self-designed retractors.
    Conclusion: The innovative working space suspension system for gasless TOETVA provided enough and stable working space and optimized the clarity of the surgical field without CO
    MeSH term(s) Humans ; Thyroidectomy/adverse effects ; Retrospective Studies ; Natural Orifice Endoscopic Surgery/adverse effects ; Hypoparathyroidism/complications ; Hypoparathyroidism/surgery ; Vocal Cord Paralysis/etiology ; Postoperative Complications/etiology ; Thyroid Neoplasms/surgery
    Language English
    Publishing date 2022-09-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-022-09528-9
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    Zs.A 2214: Show issues Location:
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  9. Article ; Online: Erratum for Lu et al., "Development of a Simple

    Lu, Gaofei / Zhang, Xi / Zheng, Weinan / Sun, Jialei / Hua, Lan / Xu, Lan / Chu, Xin-Jie / Ding, Sheng / Xiong, Wen

    Antimicrobial agents and chemotherapy

    2021  Volume 65, Issue 7, Page(s) e0082021

    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/AAC.00820-21
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    Zs.A 809: Show issues Location:
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    Einzelsignatur: Show issues

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  10. Article: Comparative transcriptome analysis of leaf, stem, and root tissues of Semiliquidambar cathayensis reveals candidate genes involved in terpenoid biosynthesis

    Tian, Xiaoming / Yan, Lihong / Jiang, Liyuan / Xiang, Guangfeng / Li, Gaofei / Zhu, Lu / Wu, Jia

    Molecular biology reports. 2022 June, v. 49, no. 6

    2022  

    Abstract: BACKGROUND: Semiliquidambar cathayensis is a traditional medicinal plant and endemic species in China. Its roots, branches, leaves, bark, and nectar are known to have therapeutic effects against rheumatoid arthritis, lumbar muscle strain, and several ... ...

    Abstract BACKGROUND: Semiliquidambar cathayensis is a traditional medicinal plant and endemic species in China. Its roots, branches, leaves, bark, and nectar are known to have therapeutic effects against rheumatoid arthritis, lumbar muscle strain, and several other diseases. However, limited knowledge regarding the molecular properties of S. cathayensis highlights the need for further research in order to elucidate the underlying pathways governing the synthesis of its active ingredients and regulation of its accumulation processes. METHODS: We conducted transcriptome sequencing of the leaf, stem and root epidermises, and stem and root xylems of S. cathayensis with three biological replicates. Moreover, candidate genes involved in terpenoid biosynthesis, such as IDI, FPPS, DXR, SQS, GPPS, and HMGR were selected for quantitative real-time PCR analysis. RESULTS: We identified 88,582 unigenes. Among which, 36,144 unigenes were annotated to the nr protein database, 21,981 to the Gene Ontology database, 11,565 to the Clusters of Orthologous Groups database, 24,209 to the Pfam database, 21,685 to the SWISS-PROT database, and 12,753 to the Kyoto Encyclopedia of Genes and Genomes (KEGG), with 5072 unigenes common to all six databases. Of those annotated using the KEGG database, 187 unigenes were related to the terpenoid metabolism pathway, and expression analysis of the related genes indicated that the mevalonate and methylerythritol 4-phosphate pathways play different roles in terpenoid biosynthesis in different tissues of S. cathayensis. CONCLUSIONS: These findings greatly expand gene resources of S. cathayensis and provide basic data for the study of the biosynthetic pathways and molecular mechanisms of terpenoids.
    Keywords bark ; biosynthesis ; gene ontology ; indigenous species ; leaves ; medicinal plants ; molecular biology ; muscles ; nectar ; quantitative polymerase chain reaction ; rheumatoid arthritis ; terpenoids ; therapeutics ; transcriptome ; transcriptomics ; unigenes ; China
    Language English
    Dates of publication 2022-06
    Size p. 5585-5593.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-022-07492-0
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