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  1. Article ; Online: Corrigendum to "SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation"[Eur. J. Pharmacol. 924 (2022) 174980].

    Gao, Anbo / Zou, Jin / Mao, Zhenjiang / Zhou, Hong / Zeng, Gaofeng

    European journal of pharmacology

    2024  Volume 968, Page(s) 176456

    Language English
    Publishing date 2024-02-22
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 80121-5
    ISSN 1879-0712 ; 0014-2999
    ISSN (online) 1879-0712
    ISSN 0014-2999
    DOI 10.1016/j.ejphar.2024.176456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Unveiling the potential of Butylphthalide: inhibiting osteoclastogenesis and preventing bone loss.

    Yanbin, Feng / Yilin, Teng / Yaomin, Mo / Deshuang, Xi / Junhong, Zhou / Gaofeng, Zeng / Shaohui, Zong

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1347241

    Abstract: Osteoporosis, resulting from overactive osteoclasts and leading to elevated fracture risk, has emerged as a global public health concern due to the aging population. Therefore, inhibiting osteoclastogenesis and bone resorption function represents a ... ...

    Abstract Osteoporosis, resulting from overactive osteoclasts and leading to elevated fracture risk, has emerged as a global public health concern due to the aging population. Therefore, inhibiting osteoclastogenesis and bone resorption function represents a crucial approach for preventing and treating osteoporosis. The purpose of this study was to examine the effects and molecular mechanisms of Butylphthalide (NBP) on the differentiation and function of osteoclasts induced by RANKL. Osteoclastogenesis was assessed through TRAP staining and bone slice assay. An animal model that underwent ovariectomy, simulating postmenopausal women's physiological characteristics, was established to investigate the impact of Butylphthalide on ovariectomy-induced bone loss. To delve deeper into the specific mechanisms, we employed Western blot, PCR, immunofluorescence, and immunohistochemical staining to detect the expression of proteins that are associated with the osteoclast signaling pathway. In this study, we found that Butylphthalide not only suppressed osteoclastogenesis and bone resorption
    Language English
    Publishing date 2024-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1347241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: What compromised the effect of reducing atelectasis by lung protective ventilation?

    Zhou, Chengcheng / Li, Xiangyu / Zhao, Gaofeng / Li, Dewei

    European journal of anaesthesiology

    2022  Volume 39, Issue 10, Page(s) 843–845

    MeSH term(s) Humans ; Lung ; Pulmonary Atelectasis/diagnosis ; Pulmonary Atelectasis/etiology ; Pulmonary Atelectasis/prevention & control ; Respiration, Artificial/adverse effects
    Language English
    Publishing date 2022-09-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 605770-6
    ISSN 1365-2346 ; 0265-0215
    ISSN (online) 1365-2346
    ISSN 0265-0215
    DOI 10.1097/EJA.0000000000001733
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Which incision is better for Lewis to Brown Norway rat liver transplantation, transverse or midline?

    Gaofeng Tang / Huibo Zhao / Guoyong Chen / Shaotang Zhou

    Heliyon, Vol 9, Iss 7, Pp e18213- (2023)

    2023  

    Abstract: Orthotopic rat liver transplantation (OLT) is a complex microsurgical procedure extensively applied to basic science, myriad complications can occur, but incision-related self-biting has not been reported after OLT. For the project of tolerance induction ...

    Abstract Orthotopic rat liver transplantation (OLT) is a complex microsurgical procedure extensively applied to basic science, myriad complications can occur, but incision-related self-biting has not been reported after OLT. For the project of tolerance induction through stem cells, we performed OLT from Lewis to Brown Norway (BN) rats as an acute rejection model and divided the study was into the transverse incision group (n = 15) and midline incision group (n = 22), while cyclosporine A was subcutaneously injected for 10-day immunosuppression use, lidocaine cream was used for pain-relieving. The recipient survival and wound status were the primary endpoint of this study. For the transverse incision group, 30-day survival rate was 40% (6/15), self-biting occurred in 13 cases in 7–39 days, the degree 1 of biting occurred in 1 cases, the degree 2 in 2 cases. The degree 3 in 10 cases, which caused death or euthanasia, the self-biting rate was 86.7% (13/15), For the midline incision group, 30-day survival rate was 100% (22/22), the degree 1 of self-biting occurred in 3 cases, no severe self-biting occurred. There were significant differences for survival (p = 0.0003) and for self-biting rate (p < 0.01) between two groups. In conclusion, incision-related self-biting behavior occurs due to incisional injury, the transverse incision is severely pain-causing; the midline one is effective to avert occurrences.
    Keywords Orthotopic liver transplantation ; Rat ; Self-biting ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 610
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Editorial: Domestication of Agronomic Traits in Legume Crops.

    Chen, Xin / Zhou, Gaofeng / Pang, Jiayin / Srinives, Peerasak

    Frontiers in genetics

    2021  Volume 12, Page(s) 707600

    Language English
    Publishing date 2021-07-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2021.707600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Which incision is better for Lewis to Brown Norway rat liver transplantation, transverse or midline?

    Tang, Gaofeng / Zhao, Huibo / Chen, Guoyong / Zhou, Shaotang

    Heliyon

    2023  Volume 9, Issue 7, Page(s) e18213

    Abstract: Orthotopic rat liver transplantation (OLT) is a complex microsurgical procedure extensively applied to basic science, myriad complications can occur, but incision-related self-biting has not been reported after OLT. For the project of tolerance induction ...

    Abstract Orthotopic rat liver transplantation (OLT) is a complex microsurgical procedure extensively applied to basic science, myriad complications can occur, but incision-related self-biting has not been reported after OLT. For the project of tolerance induction through stem cells, we performed OLT from Lewis to Brown Norway (BN) rats as an acute rejection model and divided the study was into the transverse incision group (n = 15) and midline incision group (n = 22), while cyclosporine A was subcutaneously injected for 10-day immunosuppression use, lidocaine cream was used for pain-relieving. The recipient survival and wound status were the primary endpoint of this study. For the transverse incision group, 30-day survival rate was 40% (6/15), self-biting occurred in 13 cases in 7-39 days, the degree 1 of biting occurred in 1 cases, the degree 2 in 2 cases. The degree 3 in 10 cases, which caused death or euthanasia, the self-biting rate was 86.7% (13/15), For the midline incision group, 30-day survival rate was 100% (22/22), the degree 1 of self-biting occurred in 3 cases, no severe self-biting occurred. There were significant differences for survival (
    Language English
    Publishing date 2023-07-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e18213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bimetallic metal-organic framework as a high-performance peracetic acid activator for sulfamethoxazole degradation.

    Zhou, Gaofeng / Liu, Yiqing / Zhou, Runyu / Zhang, Li / Fu, Yongsheng

    Chemosphere

    2023  Volume 349, Page(s) 140958

    Abstract: A novel 3D bimetallic metal-organic framework (MOF(Fe-Co)) was successfully prepared and its performance on sulfamethoxazole (SMX) removal in advanced oxidation process (AOP) based on peracetic acid (PAA) was evaluated. MOF(Fe-Co) exhibited an efficient ... ...

    Abstract A novel 3D bimetallic metal-organic framework (MOF(Fe-Co)) was successfully prepared and its performance on sulfamethoxazole (SMX) removal in advanced oxidation process (AOP) based on peracetic acid (PAA) was evaluated. MOF(Fe-Co) exhibited an efficient catalytic performance on PAA activation for SMX degradation under neutral condition. Increasing PAA concentration could enhance SMX removal, while the variation of MOF(Fe-Co) dosage from 0.05 to 0.2 g/L had an inappreciable effect on SMX removal. According to the results of inductively coupled plasma mass spectrometry analyses and X-ray photoelectron spectroscopy, catalytic reactions mainly occurred on the surface of MOF(Fe-Co). Organic radicals (i.e., CH
    MeSH term(s) Peracetic Acid ; Sulfamethoxazole/chemistry ; Metal-Organic Frameworks ; Water Pollutants, Chemical/analysis ; Oxidation-Reduction ; Hydrogen Peroxide/chemistry
    Chemical Substances Peracetic Acid (I6KPI2E1HD) ; Sulfamethoxazole (JE42381TNV) ; Metal-Organic Frameworks ; Water Pollutants, Chemical ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2023-12-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.140958
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Investigate large gaps and improve genetic map in narrow-leafed lupin (Lupinus angustifolius L.)

    Zhou, Gaofeng / Yang, Huaan / Renshaw, Daniel / Li, Chengdao

    Euphytica. 2023 Jan., v. 219, no. 1 p.12-12

    2023  

    Abstract: Genetic map is of vital importance to plant molecular genetic studies. It has been used for QTL mapping, gene cloning, and physical map construction. One common issue for construction of genetic maps is that one chromosome is divided into two or more ... ...

    Abstract Genetic map is of vital importance to plant molecular genetic studies. It has been used for QTL mapping, gene cloning, and physical map construction. One common issue for construction of genetic maps is that one chromosome is divided into two or more groups based on low LOD values between each group. In this study, we constructed a genetic map from a F₈ RIL population derived from two domesticated narrow-leafed lupin cultivars Uncrop and Tanjil. In the first round of analysis, 37 linkage subgroups were constructed for the 20 chromosomes. The number of subgroups was greater than the number of chromosomes. And then we merged the linkage subgroups belonging to the same chromosomes based on physical maps and other genetic maps constructed from different mapping populations. The DNA variations between the parents revealed that variation density was highly consistent with marker density in the genetic map, and that the large gaps (> 15 cM) in the same linkage groups resulted from the low DNA variations density in the large regions. Furthermore, the regions with less DNA variations between the two parents will facilitate the screening of the candidate genes located in the region. A single major QTL for grey leaf spot was identified on chromosome 19 from this mapping population.
    Keywords DNA ; Lupinus angustifolius ; chromosome mapping ; chromosomes ; cultivars ; genes ; grey leaf spot disease
    Language English
    Dates of publication 2023-01
    Size p. 12.
    Publishing place Springer Netherlands
    Document type Article ; Online
    ZDB-ID 216568-5
    ISSN 1573-5060 ; 0014-2336
    ISSN (online) 1573-5060
    ISSN 0014-2336
    DOI 10.1007/s10681-022-03139-0
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Cobalt doped graphitic carbon nitride as an effective catalyst for peracetic acid to degrade sulfamethoxazole.

    Zhou, Runyu / Zhou, Gaofeng / Liu, Yiqing / Wang, Shixiang / Fu, Yongsheng

    RSC advances

    2022  Volume 12, Issue 22, Page(s) 13810–13819

    Abstract: In this study, cobalt doped graphitic carbon nitride (Co-CN) was prepared and applied as a catalyst to activate peracetic acid (PAA) for sulfamethoxazole (SMX) degradation at neutral pH. PAA could be efficiently activated by Co-CN resulting in the ... ...

    Abstract In this study, cobalt doped graphitic carbon nitride (Co-CN) was prepared and applied as a catalyst to activate peracetic acid (PAA) for sulfamethoxazole (SMX) degradation at neutral pH. PAA could be efficiently activated by Co-CN resulting in the efficient degradation of SMX. Characterization results of fresh and used Co-CN suggested that cobalt was successfully doped in graphitic carbon nitride (g-C
    Language English
    Publishing date 2022-05-09
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d2ra00821a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Network pharmacology combined with Mendelian randomization analysis to identify the key targets of renin-angiotensin-aldosterone system inhibitors in the treatment of diabetic nephropathy.

    Zhou, Dongqi / Zhou, Ting / Tang, Shiyun / Li, Qing / Li, Wen / Gan, Gaofeng / Li, Mingqiao / Chen, Qiu

    Frontiers in endocrinology

    2024  Volume 15, Page(s) 1354950

    Abstract: Background: Diabetic Nephropathy (DN) is one of the microvascular complications of diabetes. The potential targets of renin-angiotensin-aldosterone system (RAAS) inhibitors for the treatment of DN need to be explored.: Methods: The GSE96804 and ... ...

    Abstract Background: Diabetic Nephropathy (DN) is one of the microvascular complications of diabetes. The potential targets of renin-angiotensin-aldosterone system (RAAS) inhibitors for the treatment of DN need to be explored.
    Methods: The GSE96804 and GSE1009 datasets, 729 RAAS inhibitors-related targets and 6,039 DN-related genes were derived from the public database and overlapped with the differentially expressed genes (DN vs. normal) in GSE96804 to obtain the candidate targets. Next, key targets were screened via the Mendelian randomization analysis and expression analysis. The diagnostic nomogram was constructed and assessed in GSE96804. Additionally, enrichment analysis was conducted and a 'core active ingredient-key target-disease pathway' network was established. Finally, molecular docking was performed.
    Results: In total, 60 candidate targets were derived, in which
    Conclusion: CTSC
    MeSH term(s) Humans ; Diabetic Nephropathies/drug therapy ; Diabetic Nephropathies/genetics ; Diabetic Nephropathies/metabolism ; Renin-Angiotensin System/genetics ; Molecular Docking Simulation ; Mendelian Randomization Analysis ; Network Pharmacology ; Cyclooxygenase 2/metabolism ; Acute Kidney Injury/complications ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Diphenhydramine/pharmacology ; Diphenhydramine/therapeutic use ; Diabetes Mellitus/drug therapy
    Chemical Substances Cyclooxygenase 2 (EC 1.14.99.1) ; Anti-Inflammatory Agents, Non-Steroidal ; Diphenhydramine (8GTS82S83M)
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2024.1354950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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