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  1. Article: [Transition and current state of the classification and diagnostic strategy in the ischemic stroke].

    Hoshino, Haruhiko

    Nihon rinsho. Japanese journal of clinical medicine

    2016  Volume 74, Issue 4, Page(s) 555–559

    Abstract: Since 1990, the classification of cerebrovascular disease released from the NINDS has been used. The subtypes of ischemic stroke have been diagnosed based on the diagnostic criteria used in the TOAST. For classifying the subtypes of ischemic stroke, we ... ...

    Abstract Since 1990, the classification of cerebrovascular disease released from the NINDS has been used. The subtypes of ischemic stroke have been diagnosed based on the diagnostic criteria used in the TOAST. For classifying the subtypes of ischemic stroke, we need to know the size and location of the infarcts and the presence of the stenosis or occlusion in the stem arteries. The cardiac evaluation including the long-term ECG monitor should be done for excluding the embolic source. Although the branch atheromatous disease (BAD) is not recognized in the western countries, it should be established as one clinical entity because of the high incidence rate in Japan.
    MeSH term(s) Antibodies, Antiphospholipid/blood ; Biomarkers/blood ; Diagnostic Imaging ; Humans ; Neuroimaging ; Reference Standards ; Stroke/classification ; Stroke/diagnosis
    Chemical Substances Antibodies, Antiphospholipid ; Biomarkers
    Language Japanese
    Publishing date 2016-04
    Publishing country Japan
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 390903-7
    ISSN 0047-1852
    ISSN 0047-1852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 429: Show issues Location:
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  2. Article ; Online: Underestimating hypoactive delirium?

    Hoshino, Haruhiko / Watanabe, Jun / Banno, Masahiro

    Journal of anesthesia

    2020  Volume 36, Issue 1, Page(s) 157

    MeSH term(s) Delirium/diagnosis ; Delirium/etiology ; Humans
    Language English
    Publishing date 2020-08-02
    Publishing country Japan
    Document type Letter ; Comment
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-020-02833-4
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    Zs.A 3408: Show issues Location:
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  3. Article ; Online: Safety and Effectiveness of Apixaban Versus Warfarin in Japanese Patients with Nonvalvular Atrial Fibrillation Stratified by Renal Function: A Retrospective Cohort Study.

    Morimoto, Takeshi / Hoshino, Haruhiko / Matsuo, Yukako / Ibuki, Tatsuki / Miyata, Kayoko / Koretsune, Yukihiro

    American journal of cardiovascular drugs : drugs, devices, and other interventions

    2023  Volume 23, Issue 6, Page(s) 721–733

    MeSH term(s) Humans ; Warfarin/adverse effects ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/epidemiology ; Retrospective Studies ; East Asian People ; Anticoagulants/adverse effects ; Pyridones/adverse effects ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control ; Hemorrhage/chemically induced ; Hemorrhage/epidemiology ; Kidney/physiology ; Rivaroxaban/adverse effects
    Chemical Substances Warfarin (5Q7ZVV76EI) ; apixaban (3Z9Y7UWC1J) ; Anticoagulants ; Pyridones ; Rivaroxaban (9NDF7JZ4M3)
    Language English
    Publishing date 2023-10-17
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2052547-3
    ISSN 1179-187X ; 1175-3277
    ISSN (online) 1179-187X
    ISSN 1175-3277
    DOI 10.1007/s40256-023-00611-7
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    Zs.A 5487: Show issues Location:
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  4. Article ; Online: Difficulty in Applying Recombinant Tissue Plasminogen Activator (rt-PA).

    Sugimura, Yusuke / Hoshino, Haruhiko

    Internal medicine (Tokyo, Japan)

    2016  Volume 55, Issue 8, Page(s) 1027–1028

    Language English
    Publishing date 2016
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.55.6118
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    Zs.A 240: Show issues Location:
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  5. Article ; Online: [Current state of recanalization therapy in acute ischemic stroke].

    Hoshino, Haruhiko

    Rinsho shinkeigaku = Clinical neurology

    2012  Volume 52, Issue 11, Page(s) 882–884

    Abstract: Thrombolytic therapy with intravenous tissue plasminogen activator (IV tPA) is initiated within 3 hours from the onset of ischemic stroke now. Following the publication of the results of ECASS III in 2008, IV tPA treatment has been initiated within 4.5 ... ...

    Abstract Thrombolytic therapy with intravenous tissue plasminogen activator (IV tPA) is initiated within 3 hours from the onset of ischemic stroke now. Following the publication of the results of ECASS III in 2008, IV tPA treatment has been initiated within 4.5 hours abroad. Expanding the therapeutic time window from 3 to 4.5 hours had been applied, but not approved yet in Japan. Evidence of mechanical intraarterial (IA) thrombectomy within 8 hours is not sufficient. Since a mismatch between PWI and DWI is very attractive for selecting patients for recanalization, the standardization of neuroimaging analysis must be established. For efficacious and safe recanalization, it is necessary to select patients based on accurate information on neuroimages and to establish the most useful therapy (IV tPA and/or IA thrombectomy) for each patient.
    MeSH term(s) Aged, 80 and over ; Fibrinolytic Agents/administration & dosage ; Humans ; Injections, Intravenous ; Stroke/drug therapy ; Time Factors ; Tissue Plasminogen Activator/administration & dosage
    Chemical Substances Fibrinolytic Agents ; Tissue Plasminogen Activator (EC 3.4.21.68)
    Language Japanese
    Publishing date 2012-11-08
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 604200-4
    ISSN 1882-0654 ; 0009-918X
    ISSN (online) 1882-0654
    ISSN 0009-918X
    DOI 10.5692/clinicalneurol.52.882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 223: Show issues

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  6. Article ; Online: Comparative Safety and Effectiveness of Apixaban vs. Warfarin in Oral Anticoagulant-Naïve Japanese Patients With Non-Valvular Atrial Fibrillation　- A Retrospective Chart Review Study.

    Koretsune, Yukihiro / Hoshino, Haruhiko / Matsuo, Yukako / Ibuki, Tatsuki / Morimoto, Takeshi

    Circulation journal : official journal of the Japanese Circulation Society

    2021  Volume 86, Issue 2, Page(s) 213–221

    Abstract: Background: The risk of bleeding and stroke/systemic embolism (SE) events associated with apixaban vs. warfarin among oral anticoagulant-naïve Japanese patients with non-valvular atrial fibrillation (NVAF) has not been well studied in daily clinical ... ...

    Abstract Background: The risk of bleeding and stroke/systemic embolism (SE) events associated with apixaban vs. warfarin among oral anticoagulant-naïve Japanese patients with non-valvular atrial fibrillation (NVAF) has not been well studied in daily clinical practice.Methods and Results:Clinical data for 12,090 patients were retrospectively extracted from the medical records of patients with NVAF (aged ≥20 years, creatinine clearance [CrCl] ≥15 mL/min) newly initiated to apixaban or warfarin treatment between January 1, 2010, and December 31, 2017, at 315 general practitioner clinics and 87 hospitals across Japan. After applying propensity score matching, patient characteristics were well-balanced between the apixaban and warfarin groups (4,523 patients each). The incidence rate (per 100 person-years) of major bleeding was lower in the apixaban vs. warfarin group (1.17 vs. 1.64; hazard ratio [HR], 0.71; 95% confidence interval [CI], 0.54-0.93; P=0.01), as was that of stroke/SE (1.14 vs. 1.73; HR, 0.65; 95% CI, 0.50-0.85; P<0.01). When patients were stratified by CrCl (≥50 mL/min and <50 mL/min), the P value for interaction was not statistically significant between subgroups (P=0.31 for major bleeding and P=0.32 for stroke/SE).
    Conclusions: The benefit of apixaban over warfarin for the reduction in risk of major bleeding and stroke/SE could be generalizable to daily clinical practice and to patients with reduced renal function.
    MeSH term(s) Anticoagulants/adverse effects ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/epidemiology ; Embolism ; Hemorrhage/chemically induced ; Hemorrhage/epidemiology ; Humans ; Japan/epidemiology ; Pyrazoles/adverse effects ; Pyridones/adverse effects ; Retrospective Studies ; Stroke/chemically induced ; Stroke/epidemiology ; Warfarin/adverse effects
    Chemical Substances Anticoagulants ; Pyrazoles ; Pyridones ; apixaban (3Z9Y7UWC1J) ; Warfarin (5Q7ZVV76EI)
    Language English
    Publishing date 2021-12-23
    Publishing country Japan
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2068090-9
    ISSN 1347-4820 ; 1346-9843
    ISSN (online) 1347-4820
    ISSN 1346-9843
    DOI 10.1253/circj.CJ-21-0682
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  7. Article ; Online: Electric Transport Properties of NaAlB

    Iwasaki, Suguru / Hoshino, Mihiro / Morito, Haruhiko / Kumagai, Masaya / Katsura, Yukari / Jeem, Melbert / Ono, Madoka / Nishii, Junji / Fujioka, Masaya

    Inorganic chemistry

    2022  Volume 61, Issue 10, Page(s) 4378–4383

    Abstract: A synthetic protocol was developed for obtaining a single phase of polycrystalline ... ...

    Abstract A synthetic protocol was developed for obtaining a single phase of polycrystalline NaAlB
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.1c03722
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  8. Article ; Online: A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases.

    Sasaki, Jun / Matsuoka, Masanobu / Kinoshita, Takashi / Horii, Takayuki / Tsuneyoshi, Shingo / Murata, Daiki / Takaki, Reiko / Tominaga, Masaki / Tanaka, Mio / Maruyama, Haruhiko / Kawayama, Tomotaka / Hoshino, Tomoaki

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 1

    Abstract: Paragonimiasis caused by trematodes belonging to the ... ...

    Abstract Paragonimiasis caused by trematodes belonging to the genus
    MeSH term(s) Humans ; Paragonimiasis/diagnosis ; Paragonimiasis/complications ; Cough/etiology ; Delayed Diagnosis/adverse effects ; COVID-19/complications ; Chest Pain ; COVID-19 Testing
    Language English
    Publishing date 2023-01-10
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59010137
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  9. Article ; Online: Association between intensive care unit delirium and delusional memory after critical care in mechanically ventilated patients.

    Yoshino, Yasuyo / Unoki, Takeshi / Sakuramoto, Hideaki / Ouchi, Akira / Hoshino, Haruhiko / Matsuishi, Yujiro / Mizutani, Taro

    Nursing open

    2021  Volume 8, Issue 3, Page(s) 1436–1443

    Abstract: Aim: To determine the relationship between the delirium of patients with mechanical ventilation during intensive care unit (ICU) stay and delusional memory after ICU discharge.: Design: Prospective cohort study.: Methods: Delirium in adult ... ...

    Abstract Aim: To determine the relationship between the delirium of patients with mechanical ventilation during intensive care unit (ICU) stay and delusional memory after ICU discharge.
    Design: Prospective cohort study.
    Methods: Delirium in adult patients who received mechanical ventilation for more than 24 hr was assessed twice daily using the Confusion Assessment Method for the ICU. Delusional memories were evaluated using the ICU Memory Tool 5-10 days after ICU discharge. The associations between the presence of delirium during the ICU stay and delusional memories were evaluated.
    Results: Of 60 enrolled patients, 62% had delirium during their ICU stay, and 68% experienced delusional memories 5-10 days after discharge. Delirium during ICU stay was an independent factor to experience delusional memories following discharge. Preventing delirium during ICU stay might reduce delusional memory. We recommend that patients with delirium during their ICU stay should be carefully followed up after discharge from the ICU.
    MeSH term(s) Adult ; Critical Care ; Delirium/diagnosis ; Humans ; Intensive Care Units ; Prospective Studies ; Respiration, Artificial/adverse effects
    Language English
    Publishing date 2021-01-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2809556-X
    ISSN 2054-1058 ; 2054-1058
    ISSN (online) 2054-1058
    ISSN 2054-1058
    DOI 10.1002/nop2.760
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  10. Article ; Online: PERSonality, Ehical, and PROfessional quality of life in Pediatric/Adult Intensive Nurses study: PERSEPRO PAIN study.

    Matsuishi, Yujiro / Mathis, Bryan J / Hoshino, Haruhiko / Enomoto, Yuki / Shimojo, Nobutake / Kawano, Satoru / Sakuramoto, Hideaki / Inoue, Yoshiaki

    PloS one

    2022  Volume 17, Issue 3, Page(s) e0259721

    Abstract: Background: The World Health Organization included burnout syndrome criteria that reduce both professional quality of life and work satisfaction in its 11th Revision of the International Classification of Diseases in 2019 while nursing bodies have ... ...

    Abstract Background: The World Health Organization included burnout syndrome criteria that reduce both professional quality of life and work satisfaction in its 11th Revision of the International Classification of Diseases in 2019 while nursing bodies have issued action calls to prevent burnout syndrome. Despite this, the effect of social factors, personality traits and cross-interaction on professional quality of life is still unclear.
    Aim: To reveal the association between ethical climate, personal trait and professional quality of life.
    Method: An online survey of registered nurses working in adult, pediatric or both ICUs. We used the ten-item personality measure based on The Big Five theory and Type-D personality Scale-14 then measured the ethical climate with the Hospital Ethical Climate Survey and the professional domains of burnout syndrome, secondary traumatic stress and compassion satisfaction by the Professional Quality of Life Scale Version 5 simultaneously. Multivariate analysis confirmed the triangular association of hospital ethical climate, personality traits and professional quality of life.
    Result: We enrolled 310 participants from September 2019 to February 2020. Mean age was 33.1 years (± 5.9) and about 70% were female. In the multivariate analysis, neuroticism (p = 0.03, p = 0.01) and Type D personality (both of p<0.01) were associated with burnout syndrome and secondary traumatic stress while agreeableness (p<0.01) was associated with secondary traumatic stress. Conversely, extraversion (p = 0.01), agreeableness (p<0.01) and openness (p<0.01) were associated with compassion satisfaction. We also observed interactions between hospital ethical climate and conscientiousness (p = 0.01) for burnout syndrome and secondary traumatic stress. Neuroticism was related to (p<0.01) BOS and compassion satisfaction while Type D personality (p<0.01) correlated with burnout syndrome and secondary traumatic stress.
    Conclusion: Hospital ethical climate strongly affects professional quality of life in nurses with specific personality traits. Therefore, it is important to maintain an ethical hospital climate, considering individual personalities to prevent burnout syndrome.
    MeSH term(s) Adult ; Burnout, Professional ; Child ; Compassion Fatigue ; Cross-Sectional Studies ; Female ; Humans ; Job Satisfaction ; Nurses ; Personality ; Quality of Life ; Surveys and Questionnaires
    Language English
    Publishing date 2022-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0259721
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