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Article: Experiences of Frontline Managers during the COVID-19 Pandemic: Recommendations for Organizational Resilience.

Udod, Sonia / Baxter, Pamela / Gagnon, Suzanne / Halas, Gayle / Raja, Saba

2024 Volume 12, Issue 3

Abstract: The COVID-19 pandemic caused a global health crisis directly impacting the healthcare system. Healthcare leaders influence and shape the ability of an organization to cope with and recover from a crisis such as the COVID-19 pandemic. Their actions serve ... ...

Abstract	The COVID-19 pandemic caused a global health crisis directly impacting the healthcare system. Healthcare leaders influence and shape the ability of an organization to cope with and recover from a crisis such as the COVID-19 pandemic. Their actions serve to guide and support nurses' actions through unpredictable health service demands. The purpose of this paper was to examine frontline managers' experiences and organizational leadership responses that activated organizational resilience during the COVID-19 pandemic, and to learn for ongoing and future responses to healthcare crises. Fourteen managers participated in semi-structured interviews. We found that: (1) leadership challenges (physical resources and emotional burden), (2) the influence of senior leader decision-making on managers (constant change, shortage of human resources, adapting care delivery, and cooperation and collaboration), and (3) lessons learned (managerial caring behaviours and role modelling, adaptive leadership, education and training, culture of care for self, and others) were evidence of managers' responses to the crisis. Overall, the study provides evidence of managers experiences during the early waves of the pandemic in supporting nurses and fostering organizational resilience. Knowing manager's experiences can facilitate planning, preparing, and strengthening their leadership strategies to improve work conditions is a high priority to manage and sustain nurses' mental health and wellbeing.
Language	English
Publishing date	2024-02-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare12030407
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Estimating is not measuring: the use of non-invasive estimations of somatic maturity in youth football.

Fransen, J / Skorski, S / Baxter-Jones, A D G

Science & medicine in football

2021 Volume 5, Issue 4, Page(s) 261–262

MeSH term(s)	Adolescent ; Anthropometry ; Football ; Humans ; Soccer
Language	English
Publishing date	2021-01-19
Publishing country	England
Document type	Editorial
ISSN	2473-4446
ISSN (online)	2473-4446
DOI	10.1080/24733938.2021.1975808
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Article ; Online: Motor Unit Magnetic Resonance Imaging (MUMRI) In Skeletal Muscle.

Heskamp, Linda / Birkbeck, Matthew G / Baxter-Beard, Daniel / Hall, Julie / Schofield, Ian S / Elameer, Mathew / Whittaker, Roger G / Blamire, Andrew M

Journal of magnetic resonance imaging : JMRI

2024

Abstract: Magnetic resonance imaging (MRI) is routinely used in the musculoskeletal system to measure skeletal muscle structure and pathology in health and disease. Recently, it has been shown that MRI also has promise for detecting the functional changes, which ... ...

Abstract	Magnetic resonance imaging (MRI) is routinely used in the musculoskeletal system to measure skeletal muscle structure and pathology in health and disease. Recently, it has been shown that MRI also has promise for detecting the functional changes, which occur in muscles, commonly associated with a range of neuromuscular disorders. This review focuses on novel adaptations of MRI, which can detect the activity of the functional sub-units of skeletal muscle, the motor units, referred to as "motor unit MRI (MUMRI)." MUMRI utilizes pulsed gradient spin echo, pulsed gradient stimulated echo and phase contrast MRI sequences and has, so far, been used to investigate spontaneous motor unit activity (fasciculation) and used in combination with electrical nerve stimulation to study motor unit morphology and muscle twitch dynamics. Through detection of disease driven changes in motor unit activity, MUMRI shows promise as a tool to aid in both earlier diagnosis of neuromuscular disorders and to help in furthering our understanding of the underlying mechanisms, which proceed gross structural and anatomical changes within diseased muscle. Here, we summarize evidence for the use of MUMRI in neuromuscular disorders and discuss what future research is required to translate MUMRI toward clinical practice. LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY: Stage 3.
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1146614-5
ISSN	1522-2586 ; 1053-1807
ISSN (online)	1522-2586
ISSN	1053-1807
DOI	10.1002/jmri.29218
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Zs.A 3648: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 236: Show issues

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Article ; Online: Are there Sensitive Periods for Skill Development in Male Adolescent Basketball Players?

Guimarães, Eduardo / Baxter-Jones, Adam D G / Williams, A Mark / Anderson, David I / Janeira, Manuel A / Garbeloto, Fernando / Pereira, Sara / Maia, José

Medicine and science in sports and exercise

2024

Abstract: ... prior to PHV attainment (intensity = 0.18 m·s-1·year-1), whereas in speed shot shooting (intensity = 9 ... 91 pts·year-1), passing (intensity = 19.13 pts·year-1), and slalom sprint (intensity = 0.19 m·s-1 ... dribble (intensity = 0.10 m·s-1·year-1) and defensive movement (intensity = 0.12 m·s-1·year-1) peaks ...

Abstract	Purpose: Although spurts in physical capacities during adolescence are well-known, little is known about the existence of such spurts in sport-specific skill development, especially during the period of rapid growth in stature. Our aims were to examine the timing, intensity, and sequence of basketball-specific skill spurts aligned with biological [years from peak height velocity (PHV)] rather than chronological age. We then defined putative sensitive periods (windows of optimal development) for each skill aligned to the adolescent growth spurt. Methods: Altogether, 160 adolescent male basketballers, aged 11-15 years, were tested bi-annually over three consecutive years. The years from attainment of PHV were estimated and six skill tests were aligned to each year from PHV in 3-month intervals. Skill velocities were estimated using a non-smooth polynomial model. Results: Maximal gains in slalom dribble occurred 12 months prior to PHV attainment (intensity = 0.18 m·s-1·year-1), whereas in speed shot shooting (intensity = 9.91 pts·year-1), passing (intensity = 19.13 pts·year-1), and slalom sprint (intensity = 0.19 m·s-1·year-1) these skill spurts were attained 6 months prior to PHV attainment. The mean gains in control dribble (intensity = 0.10 m·s-1·year-1) and defensive movement (intensity = 0.12 m·s-1·year-1) peaks coincided with attainment of PHV. We identified different sized windows for optimal development for each skill. Conclusions: Peak spurts in skill development, for most basketball skills, were attained at the same time as PHV. The multiple peaks observed within the defined windows of optimal development suggest that there is room for skill improvement even if gains might be greater earlier rather than later in practice. Our findings highlight the need to make coaches aware of where their players are relative to the attainment of PHV since different skills appear to develop differently relative to PHV. Such knowledge may help in designing more relevant training regimes that incorporate the athlete's current growth status so that skill development can be maximized.
Language	English
Publishing date	2024-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	603994-7
ISSN	1530-0315 ; 0195-9131 ; 0025-7990
ISSN (online)	1530-0315
ISSN	0195-9131 ; 0025-7990
DOI	10.1249/MSS.0000000000003439
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Zs.A 869: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Patient experiences and perspectives of health service access for carpal tunnel syndrome in Aotearoa New Zealand: a normalisation process theory-informed qualitative study.

Bűhler, Miranda / Atmore, Carol / Perry, Meredith / Crengle, Sue / Norris, Pauline / Baxter, G David

BMC health services research

2024 Volume 24, Issue 1, Page(s) 465

Abstract: Background: Early access to care for carpal tunnel syndrome (CTS) can avoid higher rates of surgery and permanent harm yet is often delayed, particularly for populations more likely to underutilise care.: Objective: We sought to explore patient ... ...

Abstract	Background: Early access to care for carpal tunnel syndrome (CTS) can avoid higher rates of surgery and permanent harm yet is often delayed, particularly for populations more likely to underutilise care. Objective: We sought to explore patient experiences and perspectives of health service access for CTS to inform an equity-focussed co-design of a health service for improving early care access. Methods: In this Normalisation Process Theory (NPT)-informed qualitative study we conducted semistructured in-depth interviews with 19 adults with experience of CTS. Recruitment prioritised New Zealand Māori, Pasifika, low-income, and rural populations. Data were analysed using deductive then inductive thematic analysis. Results: We identified five major themes: (1) the 'Significant Impact of CTS' of the sense-making and relational work to understand the condition, deciding when to get care, compelling clinicians to provide care, and garnering help from others; (2) 'Waiting and Paying for Care'- the enacting, relational, and appraising work to avoid long wait times unless paying privately, particularly where quality of care was low, employment relations poor, or injury compensation processes faltered; (3) circumstances of 'Occupation and CTS Onset' whereby the burden of proof to relate onset of CT symptoms to occupation created excessive relational and enacting work; (4) the 'Information Scarcity' of good information about CTS and the high relational and appraising work associated with using online resources; (5) 'Negotiating Telehealth Perspectives' where telehealth was valued if it meant earlier access for all despite the challenges it held for many. Conclusion: Quality, culturally and linguistically responsive information and communication from clinicians and health services will improve equitable early access to CTS care including realising the potential of telehealth modes of care. Policy changes that reduce individual burden of proof in injury compensation claims processes, enable time off work to attend health appointments, and increase public funding for surgical resources would improve early access to CTS care particularly for Māori and Pacific populations and those in small and rural workplaces. NPT is valuable for understanding where opportunities lie to reduce inequitable delays to accessing care including the impact of racism, particularly for populations more likely to underutilise care.
MeSH term(s)	Adult ; Humans ; Carpal Tunnel Syndrome/therapy ; Maori People ; New Zealand ; Health Services Accessibility ; Patient Outcome Assessment
Language	English
Publishing date	2024-04-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-024-10871-x
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Article ; Online: Characterization of tissue types in basal cell carcinoma images via generative modeling and concept vectors.

Thomas, S M / Lefevre, J G / Baxter, G / Hamilton, N A

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society

2021 Volume 94, Page(s) 101998

Abstract: The promise of machine learning methods to act as decision support systems for pathologists continues to grow. However, central to their successful adoption must be interpretable implementations so that people can trust and learn from them effectively. ... ...

Abstract	The promise of machine learning methods to act as decision support systems for pathologists continues to grow. However, central to their successful adoption must be interpretable implementations so that people can trust and learn from them effectively. Generative modeling, most notable in the form of adversarial generative models, is a naturally interpretable technique because the quality of the model is explicit from the quality of images it generates. Such a model can be further assessed by exploring its latent space, using human-meaningful concepts by defining concept vectors. Motivated by these ideas, we apply for the first time generative methods to histological images of basal cell carcinoma (BCC). By simultaneously learning to generate and encode realistic image patches, we extract feature rich latent vectors that correspond to various tissue morphologies, namely BCC, epidermis, keratin, papillary dermis and inflammation. We show that a logistic regression model trained on these latent vectors can achieve high classification accuracies across 6 binary tasks (86-98%). Further, by projecting the latent vectors onto learned concept vectors we can generate a score for the absence or degree of presence for a given concept, providing semantically accurate "conceptual summaries" of the various tissues types within a patch. This can be extended to generate multi-dimensional heat maps for whole-image specimens, which characterizes the tissue in a similar way to a pathologist. We additionally find that accurate concept vectors can be defined using a small labeled dataset.
MeSH term(s)	Carcinoma, Basal Cell/diagnostic imaging ; Humans ; Machine Learning ; Skin Neoplasms/diagnostic imaging
Language	English
Publishing date	2021-10-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639451-6
ISSN	1879-0771 ; 0895-6111
ISSN (online)	1879-0771
ISSN	0895-6111
DOI	10.1016/j.compmedimag.2021.101998
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Zs.A 1323: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Maternity services' responses to the COVID-19 pandemic: how Public Health England guidance was implemented in practice.

Hanley, S / Raybould, G / Baxter, E / Gray, J / Sharkey, D / Walker, K F

The Journal of hospital infection

2022 Volume 129, Page(s) 214–218

Abstract: Introduction: The rapidly evolving COVID-19 pandemic required systemic change in how healthcare was delivered to minimize virus transmission whilst maintaining safe service delivery. Deemed at 'moderate-high risk', maternity patients are an important ... ...

Abstract	Introduction: The rapidly evolving COVID-19 pandemic required systemic change in how healthcare was delivered to minimize virus transmission whilst maintaining safe service delivery. Deemed at 'moderate-high risk', maternity patients are an important patient group that require consideration. Public Health England (PHE) issued national guidance on how to adjust these services. Aim: To explore how maternity units in England implemented PHE guidance. Methods: An online survey of 22 items was distributed to individuals that had worked on an England-based maternity unit during the COVID-19 pandemic. The questionnaire was designed and tested by the multidisciplinary research team. Data was collected from November 2020 to July 2021. Findings: Forty-four participants across 33 maternity units responded. Ninety-three percent were able to test all women requiring an overnight stay for COVID-19. Only 27% reported birth partners were tested for COVID-19. Only 73% reported they were able to isolate all COVID-19-positive patients in single rooms. Eighty-four percent stated they were aware of current PHE guidance on personal protective equipment (PPE) and 82% felt 'confident' in donning/doffing of PPE. Priorities for the future include rapid testing and a focus on community service provision. Conclusions: PHE COVID-19 guidance was implemented differently in maternity units across England due to the varying resources available at each trust leading to variable ability to test and isolate patients as recommended. More specific, tailored guidance for infection control measures against COVID-19 is needed for maternity settings due to their unique position.
MeSH term(s)	Female ; Humans ; Pregnancy ; COVID-19/epidemiology ; COVID-19/prevention & control ; Pandemics/prevention & control ; SARS-CoV-2 ; Public Health ; Health Personnel ; Personal Protective Equipment
Language	English
Publishing date	2022-05-15
Publishing country	England
Document type	Journal Article
ZDB-ID	779366-2
ISSN	1532-2939 ; 0195-6701
ISSN (online)	1532-2939
ISSN	0195-6701
DOI	10.1016/j.jhin.2022.04.019
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Zs.A 1586: Show issues

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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Conference proceedings ; Online: Using impact assessment to classify unconfined pyroclastic density currents and what it means for hazard assessment at stratovolcanoes

Lerner, G. / Jenkins, S. / Charbonnier, S. / Komorowski, J. / Baxter, P. / Tennant, E.

XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

2023

Abstract: ... PDCs can be categorized based on some of their primary dynamic characteristics (e.g., velocity ... of these PDCs (e.g., in modelling) significantly impacts hazard planning for areas prone to volcanic eruptions ...

Abstract	Pyroclastic density currents (PDCs) that escape their confining channels are among the most dangerous of volcanic hazards. These unconfined PDCs are capable of inundating inhabited areas that may be unprepared for these hazards, resulting in significant loss of life and damage to infrastructure. Unconfined PDCs can be categorized based on some of their primary dynamic characteristics (e.g., velocity, concentration, dynamic pressure, temperature), which also determine the impacts that they have on humans and infrastructure. Here, we used impact assessments following eruptions at Merapi (Indonesia) in 2010 and Fuego (Guatemala) in 2018 to better understand the dynamics of the PDCs during the eruptions. By analyzing these and similar events, we identified four main categories of unconfined PDC based on their dynamic characteristics: 1. fast overspill flows, 2. slow overspill flows, 3. high-energy surges, and 4. low-energy detached surges (LEDS). How we treat the uncertainty associated with forecasting the inundation area of these PDCs (e.g., in modelling) significantly impacts hazard planning for areas prone to volcanic eruptions. We provide an example of this using hazard modelling of lava dome collapse PDCs from several high-risk volcanoes in Southeast Asia, which show a difference in the projected impacts depending on the overspill buffer with which the PDC is modelled.
Language	English
Publishing country	de
Document type	Conference proceedings ; Online
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Article ; Online: Moving towards a standardized definition of antimicrobial resistance: a comparison of the antimicrobial susceptibility profile of difficult-to-treat resistance (DTR) versus multidrug-resistant (MDR) Pseudomonas aeruginosa clinical isolates (CANWARD, 2016-2021).

Walkty, A / Karlowsky, J A / Lagacé-Wiens, P R S / Baxter, M R / Adam, H J / Bay, D C / Zhanel, G G

Diagnostic microbiology and infectious disease

2023 Volume 108, Issue 2, Page(s) 116130

Abstract: Pseudomonas aeruginosa clinical isolates demonstrating difficult-to-treat resistance (DTR) and multidrug-resistant (MDR) phenotypes were evaluated by broth microdilution. Susceptibility was lower for all antimicrobials versus DTR relative to MDR isolates. ...

Abstract	Pseudomonas aeruginosa clinical isolates demonstrating difficult-to-treat resistance (DTR) and multidrug-resistant (MDR) phenotypes were evaluated by broth microdilution. Susceptibility was lower for all antimicrobials versus DTR relative to MDR isolates. Ceftazidime-avibactam, ceftolozane-tazobactam, and imipenem-relebactam susceptibility was 35.9%, 64.5%, and 47.0% for DTR isolates and 60.5%, 80.6%, and 71.5% for MDR isolates.
MeSH term(s)	Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Pseudomonas aeruginosa ; Drug Resistance, Bacterial ; Ceftazidime/pharmacology ; Ceftazidime/therapeutic use ; Cephalosporins/pharmacology ; Cephalosporins/therapeutic use ; Pseudomonas Infections/drug therapy ; Anti-Infective Agents/pharmacology ; Azabicyclo Compounds/pharmacology ; Azabicyclo Compounds/therapeutic use ; Drug Combinations ; Microbial Sensitivity Tests ; Drug Resistance, Multiple, Bacterial
Chemical Substances	Anti-Bacterial Agents ; Ceftazidime (9M416Z9QNR) ; Cephalosporins ; Anti-Infective Agents ; Azabicyclo Compounds ; Drug Combinations
Language	English
Publishing date	2023-11-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	604920-5
ISSN	1879-0070 ; 0732-8893
ISSN (online)	1879-0070
ISSN	0732-8893
DOI	10.1016/j.diagmicrobio.2023.116130
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Zs.A 1845: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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Article: Estimation of Pediatric Dosage of Antimalarial Drugs, Using Pharmacokinetic and Physiological Approach.

Mhango, Ellen K G / Snorradottir, Bergthora S / Kachingwe, Baxter H K / Katundu, Kondwani G H / Gizurarson, Sveinbjorn

Pharmaceutics

2023 Volume 15, Issue 4

Abstract: Most of the individuals who die of malaria in sub-Saharan Africa are children. It is, therefore, important for this age group to have access to the right treatment and correct dose. Artemether-lumefantrine is one of the fixed dose combination therapies ... ...

Abstract	Most of the individuals who die of malaria in sub-Saharan Africa are children. It is, therefore, important for this age group to have access to the right treatment and correct dose. Artemether-lumefantrine is one of the fixed dose combination therapies that was approved by the World Health Organization to treat malaria. However, the current recommended dose has been reported to cause underexposure or overexposure in some children. The aim of this article was, therefore, to estimate the doses that can mimic adult exposure. The availability of more and reliable pharmacokinetic data is essential to accurately estimate appropriate dosage regimens. The doses in this study were estimated using the physiological information from children and some pharmacokinetic data from adults due to the lack of pediatric pharmacokinetic data in the literature. Depending on the approach that was used to calculate the dose, the results showed that some children were underexposed, and others were overexposed. This can lead to treatment failure, toxicity, and even death. Therefore, when designing a dosage regimen, it is important to know and include the distinctions in physiology at various phases of development that influence the pharmacokinetics of various drugs in order to estimate the dose in young children. The physiology at each time point during the growth of a child may influence how the drug is absorbed, gets distributed, metabolized, and eliminated. From the results, there is a very clear need to conduct a clinical study to further verify if the suggested (i.e., 0.34 mg/kg for artemether and 6 mg/kg for lumefantrine) doses could be clinically efficacious.
Language	English
Publishing date	2023-03-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527217-2
ISSN	1999-4923
ISSN	1999-4923
DOI	10.3390/pharmaceutics15041076
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