LIVIVO - Search results -

Search results

Result 1 - 10 of total 36

Search options

Article: Cervical Precancerous Lesions and Associated Factors Among Women Screened in Two Hospitals in the City of Douala, Cameroon.

Tagne Simo, Richard / Mbock, Claude Verdiane / Nwabo Kamdje, Armel Herve / Djoko Nono, Arsène Godlove / Nangue, Charlette / Telefo, Phelix Bruno

Cureus

2023 Volume 15, Issue 7, Page(s) e41993

Abstract: Introduction: Cervical cancer remains the second leading cause of death among women in Cameroon despite the new strategies put in place. This study was conducted in order to determine the prevalence of precancerous cervical lesions and its associated ... ...

Abstract	Introduction: Cervical cancer remains the second leading cause of death among women in Cameroon despite the new strategies put in place. This study was conducted in order to determine the prevalence of precancerous cervical lesions and its associated factors in Douala (Cameroon). Methods: A cross-sectional study was conducted over a period of nine months in two hospitals of the city of Douala, Cameroon (Laquintinie Hospital and Gyneco-Ostetric and Pediatric Hospital). Cervico-vaginal and endocervical samples were taken from women attending the above-mentioned hospitals in order to identify and characterize precancerous lesions by cytological examination and to genotype for human papillomavirus (HPV) using the Abbott RealTime High-Risk (HR) HPV kit. Data of sociodemographic characteristics, clinical history, and knowledge about cervical cancer were collected using a questionnaire. Results: Of the 196 women included in this study, 17% had precancerous lesions, including 1.53% for atypical glandular cells (AGC), 4.53% for atypical squamous cells (ASC), 4.53% for low-grade squamous intraepithelial lesion (LSIL), 5.61% for high-grade squamous intraepithelial lesion (HSIL), 0.51% for atypical squamous cells of undetermined significance (ASC-US), and 0.51% for atypical squamous cells cannot exclude HSIL (ASC-H). In addition, the prevalence of HPV infection was 18%, of which 2% was for HPV 16, 2% for HPV 18, and 14% for undetermined HPV. A positive association was recorded between the occurrence of precancerous lesions and HPV infection ( Discussion: Precancerous lesions were predominantly HSIL, and the factor most associated with these lesions was HPV infection. Conclusion: This study demonstrates that diagnosis is made at a relatively late stage due to a low level of knowledge about cervical cancer in the population.
Language	English
Publishing date	2023-07-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.41993
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Correction: Effects of Vitellaria paradoxa (C.F. Gaertn.) Aqueous leaf extract administration on Salmonella typhimurium-infected rats.

Fodouop, Siméon Pierre Chegaing / Tala, Sedric Donald / Keilah, Lunga Paul / Kodjio, Norbert / Yemele, Mefokou Didiane / Nwabo Kamdje, Armel Herve / Nji-Kah, Bridget / Tchoumboue, Joseph / Gatsing, Donatien

BMC complementary medicine and therapies

2023 Volume 23, Issue 1, Page(s) 40

Language	English
Publishing date	2023-02-07
Publishing country	England
Document type	Published Erratum
ISSN	2662-7671
ISSN (online)	2662-7671
DOI	10.1186/s12906-023-03846-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Correction

Siméon Pierre Chegaing Fodouop / Sedric Donald Tala / Lunga Paul Keilah / Norbert Kodjio / Mefokou Didiane Yemele / Armel Herve Nwabo Kamdje / Bridget Nji-kah / Joseph Tchoumboue / Donatien Gatsing

BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-

Effects of Vitellaria paradoxa (C.F. Gaertn.) Aqueous leaf extract administration on Salmonella typhimurium-infected rats

2023 Volume 1

Keywords	Other systems of medicine ; RZ201-999
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Awareness of Breast Cancer Screening among the Medical and General Population of the North Region of Cameroon.

Tagne Simo, Richard / Baiguerel, Erika Myriam / Nwabo Kamdje, Armel Hervé / Seke Etet, Paul Faustin / Ahmadou, Mohamadou / Nangue, Charlette / Telefo, Phelix Bruno

International journal of breast cancer

2021 Volume 2021, Page(s) 6663195

Abstract: Breast cancer has become a real public health problem in Cameroon, particularly in rural areas due to late diagnosis, resulting partly from the absence of national screening programs. This work is aimed at assessing breast cancer awareness in the North ... ...

Abstract	Breast cancer has become a real public health problem in Cameroon, particularly in rural areas due to late diagnosis, resulting partly from the absence of national screening programs. This work is aimed at assessing breast cancer awareness in the North Region of Cameroon. Participants were selected in six health centers surrounding the rural area of Garoua, North Region, Cameroon, and administered a questionnaire aimed at assessing their awareness about breast cancer risk factors and screening. Out of the 475 women (including 37 medical personnel) interviewed, 45.5% attended at least secondary school; 91.3% were aware of the disease with the main sources of information from those around them (64.8%), media (46.5%), and health professionals in health facilities (42.7%). 23.3% had misconceptions and myth-based ideas on the origin of the disease. Ignorance was the main reason preventing the performance of breast self-examination, and the high cost prevents individuals from going for mammography. The highest awareness rate was observed in employed women with higher level of education. Our study highlights the need to raise awareness among the populations in North Region, Cameroon, about the risk factors and clinical signs of breast cancer and the importance of screening practice for early diagnosis of breast cancer.
Language	English
Publishing date	2021-07-27
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2603566-2
ISSN	2090-3189 ; 2090-3170
ISSN (online)	2090-3189
ISSN	2090-3170
DOI	10.1155/2021/6663195
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: A new flavonoid glycoside from

Gade, Isaac Silvère / Chadeneau, Corinne / Tagne Simo, Richard / Atchade, Alex De Théodore / Talla, Emmanuel / Seite, Paul / Vannier, Brigitte / Guillard, Jérôme / Laurent, Sophie / Henoumont, Celine / Nwabo Kamdje, Armel Herve / Muller, Jean-Marc

Natural product research

2021 Volume 36, Issue 16, Page(s) 4085–4093

Abstract: The present work describes the isolation and anticancer activity ... ...

Abstract	The present work describes the isolation and anticancer activity of
MeSH term(s)	Cardiac Glycosides ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Glycosides/pharmacology ; Loranthaceae ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Leaves
Chemical Substances	Cardiac Glycosides ; Flavonoids ; Glycosides ; Plant Extracts
Language	English
Publishing date	2021-08-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2021.1963243
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Methylation Dynamics of

Malpeli, Giorgio / Innamorati, Giulio / Decimo, Ilaria / Bencivenga, Maria / Nwabo Kamdje, Armel Herve / Perris, Roberto / Bassi, Claudio

Cancers

2019 Volume 11, Issue 7

Abstract: 5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for transcriptional enhancers or inhibitor proteins binding to their target ...

Abstract	5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for transcriptional enhancers or inhibitor proteins binding to their target sequences. As a result, an additional level of regulation is added to the signals that organize the access to the chromatin and its structural components. The tumor suppressor gene
Language	English
Publishing date	2019-07-09
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers11070959
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Estimation of Reference Values of Biochemical Parameters Exploring the Renal Function in Adults in Ngaoundere, Cameroon

Armel Herve Nwabo Kamdje / Gaetan Nkem / Haverie Ghislaine Ateba Mimfoumou

International Biological and Biomedical Journal (2018)

2018

Abstract: Clinical examinations are accompanied by biological analyzes to guide or confirm the clinical diagnosis. The results of these analyzes are interpreted by comparison with reference values. Studies on the biological norms of Africans are rare if not quasi- ... ...

Abstract	Clinical examinations are accompanied by biological analyzes to guide or confirm the clinical diagnosis. The results of these analyzes are interpreted by comparison with reference values. Studies on the biological norms of Africans are rare if not quasi-nonexistent. The aim of this study was to establish population-specific reference values for biochemical indices serving as renal function biomarkers in adults living in Ngaoundere, Cameroon. 205 presumed healthy subjects (118 women and 87 men) residing in the city of Ngaoundere aged 18 to 50 years from various socio-cultural backgrounds, were included in this study. Blood urea and creatinine were tested under standard conditions. Reference intervals varied between 10-44 mg/dl and 0.6-1.4 mg/dl for urea and creatinine, respectively. Urea mean values (27.93± 8.15 mg/dl) were higher in males in comparison with females (23.56± 7.14 mg/dl) (P= 0.02). Similarly, creatinine mean values (1.11 ± 0.13 mg/dl) were higher in males in comparison with females (0.82± 0.11 mg/dl) (P= 0.04). Also, an increase in uraemia was observed with age. The gender differences for creatinemia and uraemia may be related to anthropometric features differences such as the muscle mass. The increase of uraemia with age could be explained by the increase of poor hygiene, notably the consumption of alcohol, tobacco and meat, which is mostly a male habit. The results of this study may help to a better interpretation of the biochemical indices of African subjects, and avoid errors of appreciation by excess or by default.
Keywords	Biology (General) ; QH301-705.5
Subject code	630
Language	English
Publishing date	2018-01-01T00:00:00Z
Publisher	1001 Medical Association
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Breast cancer awareness and screening practice amongst health personnel and general population of the littoral region of Cameroon.

Halmata, Mohamadou / Tagne Simo, Richard / Nganwa Kembaou, Grace / Baiguerel, Erika Myriam / Ndopwang, Lydiane C C / Nwabo Kamdje, Armel Herve / Telefo, Phelix Bruno / Nangue, Charlette / Nchiwan Nukenine, Elias

Heliyon

2021 Volume 7, Issue 7, Page(s) e07534

Abstract: Introduction: Late diagnosis has been observed as the hallmark of breast cancer in Cameroonian women where over 70% of patients report with either stage III or IV of the disease, with high mortality and dire socioeconomic consequences. The present study ...

Abstract	Introduction: Late diagnosis has been observed as the hallmark of breast cancer in Cameroonian women where over 70% of patients report with either stage III or IV of the disease, with high mortality and dire socioeconomic consequences. The present study was undertaken to assess the awareness of breast cancer, warning signs and screening methods among Health professionals and general population of Douala. Methods: Participants included in this study were health practitioners and women randomly selected and enrolled in six health facilities in the city of Douala, Littoral Region, Cameroon. A self-administered questionnaire was designed for each group and aimed at assessing their knowledge about breast cancer, warning signs and screening practices. Then, 616 women underwent breast palpation, followed by fine needle aspiration (FNA) when a nodule was found. Results: Out of a total of 737 participants (121 health personnel and 616 women) interviewed, a majority (96.3%) were aware of the disease with the main source of information being the hospital (76.0%), media (47.1%) and vocational training schools (45.4%) for health personnel; medias (39.9%), health professionals (26.1%) and their entourage (21.9%) for the population. Health workforce presented suitable awareness of the risk factors for breast cancer and its clinical signs even though 37.1% of them had misconceptions and myth-based ideas on the origin of the disease. Both the population and health personnel were aware of the possibility of early screening for breast cancer and cited breast self-examination, clinical breast examination and mammography as screening techniques. Nonetheless, screening practice amongst all women is very poor and mainly due to ignorance, high cost of mammography, together with a lack of mastery of the BSE technique and the fear of actually discovering signs of the disease. Conclusion: Our findings show lack of awareness and low practice of breast cancer screening amongst women in Douala and highlight the need to raise awareness and provide the right information to the public for early detection of breast cancer.
Language	English
Publishing date	2021-07-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2021.e07534
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A new flavonoid glycoside from Tapinanthus sp. (Loranthaceae) and evaluation of anticancer activity of extract and some isolated compounds

Natural Product Research. 2022 Aug. 18, v. 36, no. 16 p.4085-4093

2022

Abstract: The present work describes the isolation and anticancer activity of Tapinanthus sp. which is a hemi parasitic plant harvested on Combretum glutinosum, the host plant. Phytochemical study afforded a new flavonoid glycoside, tapinantoside (1) isolated for ... ...

Abstract	The present work describes the isolation and anticancer activity of Tapinanthus sp. which is a hemi parasitic plant harvested on Combretum glutinosum, the host plant. Phytochemical study afforded a new flavonoid glycoside, tapinantoside (1) isolated for the first time from natural source, alongside six known compounds (2-7). Structure of compounds were elucidated by extensive spectroscopic analyses including 1 D and 2 D NMR, mass spectrometry and by comparison with literature data. The anticancer activity of extract and some isolated compounds were evaluated on glioblastoma (U87MG, C6) and prostate (PC-3) cancer cells. The methanol leaves extract showed good anticancer activity against U87 (IC₅₀ = 21.40 µg/mL) and PC-3 cells (IC₅₀ = 10.26 µg/mL). Compound 3 powerfully inhibits the proliferation of C6 (IC₅₀ = 38.84 µM) and PC-3 cells (IC₅₀ = 21.33 µM), while its effect was moderated on U87MG cells. Compound 1 and 7 were not active on all tested cancer cell lines.
Keywords	Combretum ; Tapinanthus ; antineoplastic activity ; flavonoids ; glioblastoma ; glycosides ; host plants ; mass spectrometry ; methanol ; neoplasm cells ; parasitic plants ; research ; Tapinanthus sp. ; tapinantoside ; flavonoid glycoside ; anticancer activity
Language	English
Dates of publication	2022-0818
Size	p. 4085-4093.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2021.1963243
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Breast cancer awareness and screening practice amongst health personnel and general population of the littoral region of Cameroon

Mohamadou Halmata / Richard Simo Tagne / Grace Nganwa Kembaou / Erika Myriam Baiguerel / Lydiane C.C. Ndopwang / Armel Herve Nwabo Kamdje / Phelix Bruno Telefo / Charlette Nangue / Elias Nchiwan Nukenine

Heliyon, Vol 7, Iss 7, Pp e07534- (2021)

2021

Abstract	Introduction: Late diagnosis has been observed as the hallmark of breast cancer in Cameroonian women where over 70% of patients report with either stage III or IV of the disease, with high mortality and dire socioeconomic consequences. The present study was undertaken to assess the awareness of breast cancer, warning signs and screening methods among Health professionals and general population of Douala. Methods: Participants included in this study were health practitioners and women randomly selected and enrolled in six health facilities in the city of Douala, Littoral Region, Cameroon. A self-administered questionnaire was designed for each group and aimed at assessing their knowledge about breast cancer, warning signs and screening practices. Then, 616 women underwent breast palpation, followed by fine needle aspiration (FNA) when a nodule was found. Results: Out of a total of 737 participants (121 health personnel and 616 women) interviewed, a majority (96.3%) were aware of the disease with the main source of information being the hospital (76.0%), media (47.1%) and vocational training schools (45.4%) for health personnel; medias (39.9%), health professionals (26.1%) and their entourage (21.9%) for the population. Health workforce presented suitable awareness of the risk factors for breast cancer and its clinical signs even though 37.1% of them had misconceptions and myth-based ideas on the origin of the disease. Both the population and health personnel were aware of the possibility of early screening for breast cancer and cited breast self-examination, clinical breast examination and mammography as screening techniques. Nonetheless, screening practice amongst all women is very poor and mainly due to ignorance, high cost of mammography, together with a lack of mastery of the BSE technique and the fear of actually discovering signs of the disease. Conclusion: Our findings show lack of awareness and low practice of breast cancer screening amongst women in Douala and highlight the need to raise awareness and ...
Keywords	Breast cancer awareness ; Screening practices ; Fine needle aspiration ; Littoral Region ; Cameroon ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	610
Language	English
Publishing date	2021-07-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED