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  1. Article ; Online: The elements of eloquence by Mark Forsyth.

    Nye, Charles J S

    Practical neurology

    2024  

    Language English
    Publishing date 2024-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2170881-2
    ISSN 1474-7766 ; 1474-7758
    ISSN (online) 1474-7766
    ISSN 1474-7758
    DOI 10.1136/pn-2024-004099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6001: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: The research foundation for COVID-19 vaccine development.

    Messan, Komi S / Sulima, Pawel P / Ghosh, Dolan / Nye, Jonathan

    Frontiers in research metrics and analytics

    2023  Volume 8, Page(s) 1078971

    Abstract: The development of effective vaccines in <1 year to combat the spread of coronavirus disease 19 (COVID-19) is an example of particularly rapid progress in biomedicine. However, this was only made possible by decades of investment in scientific research. ... ...

    Abstract The development of effective vaccines in <1 year to combat the spread of coronavirus disease 19 (COVID-19) is an example of particularly rapid progress in biomedicine. However, this was only made possible by decades of investment in scientific research. Many important research commentaries and reviews have been provided to describe the various contributions and scientific breakthroughs that led to the development of COVID-19 vaccines. In this work, we sought to complement those efforts by adding a systematic and quantitative study of the research foundations that led to these vaccines. Here, we analyzed citations from COVID-19 vaccine research articles to determine which scientific areas of study contributed the most to this research. Our findings revealed that coronavirus research was cited most often, and by a large margin. However, significant contributions were also seen from a diverse set of fields such as cancer, diabetes, and HIV/AIDS. In addition, we examined the publication history of the most prolific authors of COVID-19 vaccine research to determine their research expertise prior to the pandemic. Interestingly, although COVID-19 vaccine research relied most heavily on previous coronavirus work, we find that the most prolific authors on these publications most often had expertise in other areas including influenza, cancer, and HIV/AIDS. Finally, we used machine learning to identify and group together publications based on their major topic areas. This allowed us to elucidate the differences in citations between research areas. These findings highlight and quantify the relevance of prior research from a variety of scientific fields to the rapid development of a COVID-19 vaccine. This study also illustrates the importance of funding and sustaining a diverse research enterprise to facilitate a rapid response to future pandemics.
    Language English
    Publishing date 2023-03-24
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2504-0537
    ISSN (online) 2504-0537
    DOI 10.3389/frma.2023.1078971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Asymptomatic Progression of Stress Injury to Complete Long Bone Fracture in Three Military Personnel.

    Ferguson, Lauren P / Boden, Barry P / Bailey, Jonathan / Nye, Nathaniel S

    Current sports medicine reports

    2023  Volume 22, Issue 12, Page(s) 405–409

    MeSH term(s) Humans ; Military Personnel ; Fractures, Stress/diagnostic imaging ; Fractures, Stress/therapy
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2080040-X
    ISSN 1537-8918 ; 1537-890X
    ISSN (online) 1537-8918
    ISSN 1537-890X
    DOI 10.1249/JSR.0000000000001120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5922: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Book: Governance in a globalizing world

    Nye, Joseph S.

    2000  

    Author's details Joseph S. Nye ..., ed
    Keywords Globalisierung ; Governance
    Subject Weltwirtschaft ; Weltgesellschaft ; Globalisation ; Globalization
    Language English
    Size XII, 386 S. : graph. Darst.
    Publisher Visions of Governance for the 21st Century u.a.
    Publishing place Cambridge, Mass
    Publishing country United States
    Document type Book
    HBZ-ID HT012972190
    ISBN 0-8157-6408-1 ; 0-8157-6407-3 ; 978-0-8157-6408-3 ; 978-0-8157-6407-6
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    008/4263 available for loan (reading room) Freihandmagazin (U1)

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  5. Article ; Online: Short-term outcomes for surgical correction of feline medial patellar luxations via semi-cylindrical recession trochleoplasty.

    Deom, Kristen / Conzemius, Michael G / Tarricone, Jason / Nye, Carolyn / Veytsman, Stan

    JFMS open reports

    2023  Volume 9, Issue 2, Page(s) 20551169231179543

    Abstract: ... postoperatively. At the final rechecks, all cats had resolution of lameness of the operated limb(s) and no ...

    Abstract Case series summary: Three cats (five stifles) were diagnosed with varying degrees of pelvic limb lameness secondary to medial patellar luxations (MPLs). Lameness did not resolve with medical management in any cat before referral for orthopedic evaluation. All cats underwent semi-cylindrical recession trochleoplasty (SCRT), medial fascial release and lateral imbrication for surgical repair of MPLs. All cats were re-evaluated at 3 and 8 weeks postoperatively and two cats were also evaluated at 16 weeks postoperatively. At the final rechecks, all cats had resolution of lameness of the operated limb(s) and no evidence of recurrence of patellar luxation.
    Relevance and novel information: This case series demonstrated SCRT with soft tissue reconstruction as an acceptable option for surgical correction in three cats with MPLs. Short-term outcomes revealed minor complications and all patellae remained centralized.
    Language English
    Publishing date 2023-07-05
    Publishing country England
    Document type Case Reports
    ZDB-ID 2822177-1
    ISSN 2055-1169 ; 2055-1169
    ISSN (online) 2055-1169
    ISSN 2055-1169
    DOI 10.1177/20551169231179543
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Alterations in adolescent brain serotonin (5HT)

    Wakeford, Alison G P / Nye, Jonathon A / Morin, Elyse L / Mun, Jiyoung / Meyer, Jerrold S / Goodman, Mark / Howell, Leonard L / Sanchez, Mar M

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2024  

    Abstract: Stress affects brain serotonin (5HT) and dopamine (DA) function, and the effectiveness of 5HT and DA to regulate stress and emotional responses. However, our understanding of the long-term impact of early life adversity (ELA) on primate brain ... ...

    Abstract Stress affects brain serotonin (5HT) and dopamine (DA) function, and the effectiveness of 5HT and DA to regulate stress and emotional responses. However, our understanding of the long-term impact of early life adversity (ELA) on primate brain monoaminergic systems during adolescence is scarce and inconsistent. Filling this gap in the literature is critical, given that the emergence of psychopathology during adolescence has been related to deficits in these systems. Here, we use a translational nonhuman primate (NHP) model of ELA (infant maltreatment by the mother) to examine the long-term impact of ELA on adolescent 5HT
    Language English
    Publishing date 2024-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-023-01784-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2379: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Information geometry for phylogenetic trees.

    Garba, M K / Nye, T M W / Lueg, J / Huckemann, S F

    Journal of mathematical biology

    2021  Volume 82, Issue 3, Page(s) 19

    Abstract: We propose a new space of phylogenetic trees which we call wald space. The motivation is to develop a space suitable for statistical analysis of phylogenies, but with a geometry based on more biologically principled assumptions than existing spaces: in ... ...

    Abstract We propose a new space of phylogenetic trees which we call wald space. The motivation is to develop a space suitable for statistical analysis of phylogenies, but with a geometry based on more biologically principled assumptions than existing spaces: in wald space, trees are close if they induce similar distributions on genetic sequence data. As a point set, wald space contains the previously developed Billera-Holmes-Vogtmann (BHV) tree space; it also contains disconnected forests, like the edge-product (EP) space but without certain singularities of the EP space. We investigate two related geometries on wald space. The first is the geometry of the Fisher information metric of character distributions induced by the two-state symmetric Markov substitution process on each tree. Infinitesimally, the metric is proportional to the Kullback-Leibler divergence, or equivalently, as we show, to any f-divergence. The second geometry is obtained analogously but using a related continuous-valued Gaussian process on each tree, and it can be viewed as the trace metric of the affine-invariant metric for covariance matrices. We derive a gradient descent algorithm to project from the ambient space of covariance matrices to wald space. For both geometries we derive computational methods to compute geodesics in polynomial time and show numerically that the two information geometries (discrete and continuous) are very similar. In particular, geodesics are approximated extrinsically. Comparison with the BHV geometry shows that our canonical and biologically motivated space is substantially different.
    MeSH term(s) Algorithms ; Markov Chains ; Models, Biological ; Phylogeny
    Language English
    Publishing date 2021-02-15
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187101-8
    ISSN 1432-1416 ; 0303-6812
    ISSN (online) 1432-1416
    ISSN 0303-6812
    DOI 10.1007/s00285-021-01553-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1495: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Vaccination with

    Timm, Morgan R / Tamadonfar, Kevin O / Nye, Taylor M / Pinkner, Jerome S / Dodson, Karen W / Ellebedy, Ali H / Hultgren, Scott J

    Research square

    2023  

    Abstract: Catheter-associated urinary tract infections (CAUTIs) contribute greatly to the burden of healthcare associated infections. ...

    Abstract Catheter-associated urinary tract infections (CAUTIs) contribute greatly to the burden of healthcare associated infections.
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-3213777/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Limitations associated with thermoregulation and cardiovascular research assessing laborers performing work in the heat.

    Morrissey, Margaret C / Langan, Sean P / Brewer, Gabrielle J / Struder, Jeb F / Navarro, John S / Nye, Megan N / Casa, Douglas J

    American journal of industrial medicine

    2023  Volume 66, Issue 4, Page(s) 267–280

    Abstract: Purpose: To quantify the current literature and limitations associated with research examining thermoregulatory and cardiovascular strain in laborers working in the heat.: Methods: PubMed, SCOPUS, and SPORTDiscus were searched for terms related to ... ...

    Abstract Purpose: To quantify the current literature and limitations associated with research examining thermoregulatory and cardiovascular strain in laborers working in the heat.
    Methods: PubMed, SCOPUS, and SPORTDiscus were searched for terms related to the cardiovascular system, heat stress, and physical work. Qualifying studies included adult participants (18-65 years old), a labor-intensive environment or exercise protocol simulating a labor environment, a minimum duration of 120 min of physical work, and environmental heat stress (ambient temperature ≥26.0°C and ≥30% relative humidity). Studies included at least one of the following outcomes: pre- and peak physical work, core temperature, heart rate (HR), systolic blood pressure, diastolic blood pressure, HR variability, and rate pressure product.
    Results: Twenty-one out of 1559 potential studies qualified from our search. There was a total of 598 participants (mean = 28 ± 50 participants per study, range = 4-238 participants per study), which included 51 females (8.5%) and 547 males (91.5%). Of the participants, 3.8% had cardiovascular risk factors (diabetes: n = 10; hypertension: n = 13) and 96.2% were characterized as "healthy". Fifty-seven percent of the included studies were performed in a laboratory setting.
    Conclusions: Studies were predominantly in men (91.5%), laboratory settings (57%), and "healthy" individuals (96.2%). To advance equity in protection against occupational heat stress and better inform future heat safety recommendations to protect all workers, future studies must focus on addressing these limitations. Employers, supervisors, and other safety stakeholders should consider these limitations while implementing current heat safety recommendations.
    MeSH term(s) Male ; Adult ; Female ; Humans ; Adolescent ; Young Adult ; Middle Aged ; Aged ; Body Temperature Regulation/physiology ; Blood Pressure ; Hypertension ; Exercise/physiology ; Heart Rate ; Heat Stress Disorders/prevention & control ; Cardiovascular System ; Hot Temperature
    Language English
    Publishing date 2023-02-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604538-8
    ISSN 1097-0274 ; 0271-3586
    ISSN (online) 1097-0274
    ISSN 0271-3586
    DOI 10.1002/ajim.23462
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1605: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Leaky barriers to gene sharing between locally co-existing coagulase-negative Staphylococcus species.

    Ikhimiukor, Odion O / Souza, Stephanie S R / Marcovici, Michael M / Nye, Griffin J / Gibson, Robert / Andam, Cheryl P

    Communications biology

    2023  Volume 6, Issue 1, Page(s) 482

    Abstract: Coagulase-negative Staphylococcus (CoNS) are opportunistic pathogens implicated in many human and animal infections. The evolutionary history of CoNS remains obscure because of the historical lack of recognition for their clinical importance and poor ... ...

    Abstract Coagulase-negative Staphylococcus (CoNS) are opportunistic pathogens implicated in many human and animal infections. The evolutionary history of CoNS remains obscure because of the historical lack of recognition for their clinical importance and poor taxonomic sampling. Here, we sequenced the genomes of 191 CoNS isolates representing 15 species sampled from diseased animals diagnosed in a veterinary diagnostic laboratory. We found that CoNS are important reservoirs of diverse phages, plasmids and mobilizable genes encoding antimicrobial resistance, heavy metal resistance, and virulence. Frequent exchange of DNA between certain donor-recipient partners suggests that specific lineages act as hubs of gene sharing. We also detected frequent recombination between CoNS regardless of their animal host species, indicating that ecological barriers to horizontal gene transfer can be surmounted in co-circulating lineages. Our findings reveal frequent but structured patterns of transfer that exist within and between CoNS species, which are driven by their overlapping ecology and geographical proximity.
    MeSH term(s) Animals ; Humans ; Coagulase/genetics ; Staphylococcus/genetics ; Plasmids ; Bacteriophages
    Chemical Substances Coagulase
    Language English
    Publishing date 2023-05-03
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-023-04877-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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