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  1. Article: Radiation-spin interaction, Gilbert damping, and spin torque.

    Ho, Jeongwon / Khanna, F C / Choi, B C

    Physical review letters

    2004  Volume 92, Issue 9, Page(s) 97601

    Abstract: Magnetization relaxation processes, which are represented by the Gilbert damping term and the spin ... torque term in the Landau-Lifshitz-Gilbert (LLG) equation, are described by the radiation-spin ... shown that the LLG equation including the Gilbert damping term and the spin torque term is derived ...

    Abstract Magnetization relaxation processes, which are represented by the Gilbert damping term and the spin torque term in the Landau-Lifshitz-Gilbert (LLG) equation, are described by the radiation-spin interaction (RSI), where the radiation field is produced by magnetization precessional motion itself. It is shown that the LLG equation including the Gilbert damping term and the spin torque term is derived from the spin Hamiltonian containing the RSI. The derivation of the LLG equation is given in a self-consistent method. It is also shown that, according to RSI, the magnitude of the magnetization vector deviates from the magnetization saturation with the order of O(alpha(2)), where alpha is the Gilbert damping parameter.
    Language English
    Publishing date 2004-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.92.097601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Automated determination of gallium in seawater using seaFAST pre-concentration and high-resolution inductively-coupled plasma mass spectrometry.

    Gilbert, Melissa / Ho, Peng / Whitmore, Laura / Shiller, Alan

    Analytica chimica acta

    2023  Volume 1241, Page(s) 340799

    Abstract: There has been increased interest in dissolved gallium (Ga) in natural waters due to its long residence time and its usefulness in tracking water masses; however, current analytical approaches are time consuming and labor intensive (e.g., magnesium ... ...

    Abstract There has been increased interest in dissolved gallium (Ga) in natural waters due to its long residence time and its usefulness in tracking water masses; however, current analytical approaches are time consuming and labor intensive (e.g., magnesium hydroxide co-precipitation method, (Mg(OH)
    Language English
    Publishing date 2023-01-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1483436-4
    ISSN 1873-4324 ; 0003-2670
    ISSN (online) 1873-4324
    ISSN 0003-2670
    DOI 10.1016/j.aca.2023.340799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Differential involvement of amyloidogenic evolvability in oligodendropathies; Multiple Sclerosis and Multiple System Atrophy.

    Wei, Jianshe / Ho, Gilbert / Masliah, Eliezer / Hashimoto, Makoto

    Prion

    2023  Volume 17, Issue 1, Page(s) 29–34

    Abstract: Although multiple sclerosis (MS) and multiple system atrophy (MSA) are both characterized by impaired oligodendrocytes (OLs), the aetiological relevance remains obscure. Given inherent stressors affecting OLs, the objective of the present study was to ... ...

    Abstract Although multiple sclerosis (MS) and multiple system atrophy (MSA) are both characterized by impaired oligodendrocytes (OLs), the aetiological relevance remains obscure. Given inherent stressors affecting OLs, the objective of the present study was to discuss the possible role of amyloidogenic evolvability (aEVO) in these conditions. Hypothetically, in aEVO, protofibrils of amyloidogenic proteins (APs), including β-synuclein and β-amyloid, might form in response to diverse stressors in parental brain. Subsequently, the AP protofibrils might be transmitted to offspring via germ cells in a prion-like fashion. By virtue of the stress information conferred by protofibrillar APs, the OLs in offspring's brain might be more resilient to forthcoming stressors, perhaps reducing MS risk. aEVO could be comparable to a gene for the inheritance of acquired characteristics. On the contrary, during ageing, MSA risk is increased through antagonistic pleiotropy. Consistently, the expression levels of APs are reduced in MS, but are increased in MSA compared to controls. Furthermore, β-synuclein, the non-amyloidogenic homologue of β-synuclein, might exert a buffering effect on aEVO, and abnormal β-synuclein could also increase MS and MSA disease activity. Collectively, a better understanding of the role of aEVO in the OL diseases might lead to novel interventions for such chronic degenerative conditions.
    MeSH term(s) Humans ; Multiple System Atrophy/genetics ; Multiple System Atrophy/metabolism ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism ; beta-Synuclein/metabolism ; Multiple Sclerosis/genetics ; Multiple Sclerosis/metabolism ; Brain/metabolism ; Amyloidogenic Proteins/genetics ; Amyloidogenic Proteins/metabolism
    Chemical Substances alpha-Synuclein ; beta-Synuclein ; Amyloidogenic Proteins
    Language English
    Publishing date 2023-02-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267671-5
    ISSN 1933-690X ; 1933-690X
    ISSN (online) 1933-690X
    ISSN 1933-690X
    DOI 10.1080/19336896.2023.2172912
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Differential involvement of amyloidogenic evolvability in oligodendropathies; Multiple Sclerosis and Multiple System Atrophy

    Jianshe Wei / Gilbert Ho / Eliezer Masliah / Makoto Hashimoto

    Prion, Vol 17, Iss 1, Pp 29-

    2023  Volume 34

    Abstract: ABSTRACTAlthough multiple sclerosis (MS) and multiple system atrophy (MSA) are both characterized by impaired oligodendrocytes (OLs), the aetiological relevance remains obscure. Given inherent stressors affecting OLs, the objective of the present study ... ...

    Abstract ABSTRACTAlthough multiple sclerosis (MS) and multiple system atrophy (MSA) are both characterized by impaired oligodendrocytes (OLs), the aetiological relevance remains obscure. Given inherent stressors affecting OLs, the objective of the present study was to discuss the possible role of amyloidogenic evolvability (aEVO) in these conditions. Hypothetically, in aEVO, protofibrils of amyloidogenic proteins (APs), including β-synuclein and β-amyloid, might form in response to diverse stressors in parental brain. Subsequently, the AP protofibrils might be transmitted to offspring via germ cells in a prion-like fashion. By virtue of the stress information conferred by protofibrillar APs, the OLs in offspring’s brain might be more resilient to forthcoming stressors, perhaps reducing MS risk. aEVO could be comparable to a gene for the inheritance of acquired characteristics. On the contrary, during ageing, MSA risk is increased through antagonistic pleiotropy. Consistently, the expression levels of APs are reduced in MS, but are increased in MSA compared to controls. Furthermore, β-synuclein, the non-amyloidogenic homologue of β-synuclein, might exert a buffering effect on aEVO, and abnormal β-synuclein could also increase MS and MSA disease activity. Collectively, a better understanding of the role of aEVO in the OL diseases might lead to novel interventions for such chronic degenerative conditions.
    Keywords Multiple sclerosis (MS) ; multiple system atrophy (MSA) ; oligodendrocytes (OLs) ; amyloidogenic evolvability (aEVO) ; amyloidogenic proteins (APs) ; β-amyloid (aβ) ; Neurology. Diseases of the nervous system ; RC346-429 ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Feasibility of Using TriClip Guide for Combined MitraClip and TriClip Transcatheter Edge-to-Edge Repair: First-in-Human Experience.

    So, Kent Chak-Yu / Kam, Kevin Ka-Ho / Tang, Gilbert H L / Lee, Alex P W

    JACC. Cardiovascular interventions

    2024  Volume 17, Issue 8, Page(s) 1071–1072

    MeSH term(s) Humans ; Cardiac Catheterization/instrumentation ; Feasibility Studies ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/instrumentation ; Mitral Valve/surgery ; Mitral Valve/diagnostic imaging ; Mitral Valve/physiopathology ; Mitral Valve Insufficiency/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/physiopathology ; Prosthesis Design ; Recovery of Function ; Treatment Outcome
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Video-Audio Media ; Case Reports ; Letter
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2024.02.024
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  6. Article ; Online: Determinants of parental vaccine hesitancy in Canada: results from the 2017 Childhood National Immunization Coverage Survey.

    Chen, Ruoke / Guay, Mireille / Gilbert, Nicolas L / Dubé, Eve / Witteman, Holly O / Hakim, Hina

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 2327

    Abstract: Background: In 2019, the World Health Organization (WHO) designated vaccine hesitancy as one of the ten leading threats to global health. Vaccine hesitancy exists when vaccination services are available and accessible, but vaccine uptake is lower than ... ...

    Abstract Background: In 2019, the World Health Organization (WHO) designated vaccine hesitancy as one of the ten leading threats to global health. Vaccine hesitancy exists when vaccination services are available and accessible, but vaccine uptake is lower than anticipated. It is often attributed to lack of trust in vaccine safety and effectiveness, or low level of concern about the risk of many vaccine-preventable diseases. This study aimed to examine the sociodemographic factors associated with parental vaccine hesitancy and vaccine refusal in Canada using data from the 2017 Childhood National Immunization Coverage Survey (CNICS).
    Method: The 2017 CNICS was a cross-sectional and nationally representative survey to estimate national vaccine uptake and to collect information about parents' Knowledge, Attitudes and Beliefs (KAB) regarding vaccination. Using the KAB questions, parental vaccine hesitancy (i.e., parental hesitation, delay or refusal of at least one recommended vaccination) and refusal (i.e., unvaccinated children) by sociodemographic factors was estimated using weighted prevalence proportions. A multinomial logistic regression model was fitted to examine associations between parental vaccine hesitancy or refusal and sociodemographic factors among parents of two-year-old children in Canada. Adjusted odds ratios (aOR) of being vaccine-hesitant or vaccine-refusing versus being non-vaccine-hesitant were generated.
    Results: Both unadjusted and adjusted logistic regressions models showed that parents with lower household income (aOR 1.7, 95% CI 1.2-2.5), and those with a higher number of children in the household (aOR 2.2, 95% CI 1.4-3.5) had higher vaccine hesitancy. Conversely, lower vaccine hesitancy was observed among non-immigrant parents (aOR 0.4, 95% CI 0.3-0.6). In addition, lower household income (aOR 4.0, 95% CI 1.3-12.9), and higher number of children in the household (aOR 6.9, 95% CI 2.1-22.9) were significantly associated with parental vaccine refusal. Regional variations were also observed.
    Conclusion: Several sociodemographic determinants are associated with parental vaccine hesitancy and refusal. The findings of the study could help public health officials and policymakers to develop and implement targeted interventions to improve childhood vaccination programs.
    MeSH term(s) Child ; Humans ; Child, Preschool ; Vaccination Coverage ; Vaccination Hesitancy ; Cross-Sectional Studies ; Vaccination ; Canada ; Parents ; Vaccines ; Health Knowledge, Attitudes, Practice
    Chemical Substances Vaccines
    Language English
    Publishing date 2023-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-17079-4
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  7. Article: Therapeutic Potential of

    Wei, Jianshe / Ho, Gilbert / Takamatsu, Yoshiki / Masliah, Eliezer / Hashimoto, Makoto

    Parkinson's disease

    2021  Volume 2021, Page(s) 6318067

    Abstract: The majority of Parkinson's disease (PD) is sporadic in elderly and is characterized ... ...

    Abstract The majority of Parkinson's disease (PD) is sporadic in elderly and is characterized by
    Language English
    Publishing date 2021-11-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2573854-9
    ISSN 2042-0080 ; 2090-8083
    ISSN (online) 2042-0080
    ISSN 2090-8083
    DOI 10.1155/2021/6318067
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  8. Article ; Online: Addendum: Histological and molecular analysis of a progressive diffuse intrinsic pontine glioma and synchronous metastatic lesions: a case report.

    Nazarian, Javad / Mason, Gary E / Ho, Cheng Ying / Panditharatna, Eshini / Kambhampati, Madhuri / Vezina, L Gilbert / Packer, Roger J / Hwang, Eugene I

    Oncotarget

    2023  Volume 14, Page(s) 449

    Language English
    Publishing date 2023-05-12
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.28286
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  9. Article ; Online: Chemical Composition and Strain at Interfaces between Different Morphologies in Block Copolymer Thin Films.

    Ho, Kevin / Kim, Kris S / de Beer, Sissi / Walker, Gilbert C

    Langmuir : the ACS journal of surfaces and colloids

    2021  Volume 37, Issue 43, Page(s) 12723–12731

    Abstract: Transitional composition between two thin-film morphologies of the block copolymer, polystyrene- ...

    Abstract Transitional composition between two thin-film morphologies of the block copolymer, polystyrene-
    Language English
    Publishing date 2021-10-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.1c02169
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  10. Article ; Online: Reconsideration of Alzheimer's Disease Therapy from a Viewpoint of Amyloidogenic Evolvability.

    Ho, Gilbert / Choo, Pei Chen / Waragai, Masaaki / Inoue, Satoshi / Masliah, Eliezer / Hashimoto, Makoto

    Journal of Alzheimer's disease reports

    2022  Volume 6, Issue 1, Page(s) 207–210

    Abstract: Presuming that Alzheimer's disease (AD) might represent an antagonistic pleiotropic phenomenon derived from the evolvability of multiple amyloidogenic proteins, targeting such proteins simultaneously could enhance therapeutic efficacy. Furthermore, ... ...

    Abstract Presuming that Alzheimer's disease (AD) might represent an antagonistic pleiotropic phenomenon derived from the evolvability of multiple amyloidogenic proteins, targeting such proteins simultaneously could enhance therapeutic efficacy. Furthermore, considering that amyloid-β (Aβ) immunotherapies during reproductive life stage might adversely decrease Aβ evolvability in an offspring's brain, the disease-modifying Aβ immunotherapies should be limited to post-reproductive time in lifespan. Thus, current Aβ immunotherapy strategies should be revised accordingly. Given that the "adiponectin paradox" might underlie both amyloidosis and cognitive dysfunction in aging brain, blocking activin signaling situated downstream of the adiponectin paradox might be an alternative strategy to prevent AD.
    Language English
    Publishing date 2022-04-27
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2542-4823
    ISSN (online) 2542-4823
    DOI 10.3233/ADR-210021
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