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  1. Article: Awareness of First Aid Management of Epistaxis in Children Among Parents in Arar, Saudi Arabia.

    Elsayed Elboraei, Yahia Abdelgawad / Alanazi, Mada Muteb / Fawzan Almesned, Bishri / Alanazi, Wujud Khalid / Almutairi, Dhai Nasser / Alanazi, Iftikhar Lafi N / Alanazi, Ghadah Khalid H / Fawzy, Manal S

    Cureus

    2023  Volume 15, Issue 11, Page(s) e49557

    Abstract: Background: Epistaxis is a relatively common condition, particularly among children, necessitating that parents be well informed about its effective management.: Objectives: This study aims to explore the current level of awareness among parents in ... ...

    Abstract Background: Epistaxis is a relatively common condition, particularly among children, necessitating that parents be well informed about its effective management.
    Objectives: This study aims to explore the current level of awareness among parents in the Arar region, Saudi Arabia, regarding the first aid management of epistaxis and to highlight the importance of education in empowering parents to handle such situations.
    Methods: A cross-sectional study was conducted using a survey distributed among the Arar population (aged >18 years) who had at least one child and were willing to participate. Data were collected between mid-July and the end of September 2023 using a self-administered questionnaire, which included a consent form, sociodemographic and background items, and epistaxis knowledge-related questions.
    Results: A total of 342 participants (27.8% males) completed the questionnaire. It was observed that 47.4% of the participants' children had experienced epistaxis. Only around half of them (n=84; 51.9%) had received first aid management for epistaxis, and only 40.4% of the parents correctly identified all the necessary steps for managing it through first aid. There was inadequate knowledge regarding the causes/risk factors and appropriate first aid techniques for epistaxis. Certain sociodemographic factors were significantly associated with better knowledge of first aid management of epistaxis, such as female gender (p = 0.003), older participants (p = 0.002), and a higher educational level (p = 0.001).
    Conclusion: The study found low awareness of first aid management of epistaxis among parents residing in Arar, Saudi Arabia. Factors related to the demographic characteristics of the study participants were associated with this level of knowledge. These findings emphasize the need to improve awareness about first aid management of epistaxis, particularly among younger individuals, males, and those with limited education. Effective interventions should be developed to enhance first aid training, considering the specific risk factors associated with epistaxis.
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.49557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cobalt-modulated dual emission carbon dots for ratiometric fluorescent vancomycin detection.

    Alhazzani, Khalid / Alanazi, Ahmed Z / Mostafa, Aya M / Barker, James / El-Wekil, Mohamed M / Ali, Al-Montaser Bellah H

    RSC advances

    2024  Volume 14, Issue 8, Page(s) 5609–5616

    Abstract: This work presents a simple yet selective fluorometric protocol for the quantification of vancomycin, an important antibiotic for treating infections caused by Gram-positive bacteria. A novel ratiometric fluorometric method for the determination of ... ...

    Abstract This work presents a simple yet selective fluorometric protocol for the quantification of vancomycin, an important antibiotic for treating infections caused by Gram-positive bacteria. A novel ratiometric fluorometric method for the determination of vancomycin is developed based on dual emissive carbon dots (DECDs) with emission at 382 nm and 570 nm in combination with Co
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra08899e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical Peri-Implant Parameters and Marginal Bone Loss for Early Mandibular Implant Overdentures: A Follow-Up of 60 Months.

    AlHelal, Abdulaziz A / Alzaid, Abdulaziz A / Almujel, Saad H / Alsaloum, Mohammed / Alanazi, Khalid K / Althubaitiy, Ramzi O / Al-Aali, Khulud A

    Medicina (Kaunas, Lithuania)

    2024  Volume 60, Issue 4

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Humans ; Female ; Denture, Overlay ; Male ; Prospective Studies ; Alveolar Bone Loss/etiology ; Middle Aged ; Follow-Up Studies ; Mandible/surgery ; Aged ; Dental Prosthesis, Implant-Supported/methods ; Dental Prosthesis, Implant-Supported/adverse effects ; Dental Implants/adverse effects ; Cohort Studies ; Adult
    Chemical Substances Dental Implants
    Language English
    Publishing date 2024-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina60040588
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Selective fluorescence turn-on detection of combination cisplatin-etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe.

    Alhazzani, Khalid / Alanazi, Ahmed Z / Mostafa, Aya M / Barker, James / El-Wekil, Mohamed M / Ali, Al-Montaser Bellah H

    RSC advances

    2024  Volume 14, Issue 4, Page(s) 2380–2390

    Abstract: Cisplatin (CIS) and etoposide (ETP) combination therapy is highly effective for treating various cancers. However, the potential for pharmacokinetic interactions between these drugs necessitates selective sensing methods to quantitate both CIS and ETP ... ...

    Abstract Cisplatin (CIS) and etoposide (ETP) combination therapy is highly effective for treating various cancers. However, the potential for pharmacokinetic interactions between these drugs necessitates selective sensing methods to quantitate both CIS and ETP levels in patient's plasma. This work develops a dual fluorescence probe strategy using glutathione-capped copper nanoclusters (GSH-CuNCs) and nitrogen-doped carbon dots (N-CDs) for the simultaneous analysis of CIS and ETP. The fluorescence signal of GSH-CuNCs at 615 nm increased linearly with CIS concentration while the N-CD emission at 480 nm remained unaffected. Conversely, the N-CD fluorescence was selectively enhanced by ETP with no interference with the CuNC fluorescence. Extensive materials characterization including UV-vis, fluorescence spectroscopy, XRD, and TEM confirmed the synthesis of the nanoprobes. The sensor showed high sensitivity with limits of detection of 6.95 ng mL
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra07844b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Knowledge and Attitude of Parents Regarding the Human Papillomavirus Vaccine as a New Component in the Saudi Vaccination Schedule.

    Bin Alamir, Abdulrahman A / Almotairi, Abdullah H / Almutairi, Fahad H / Almujel, Khaled N / Almhmd, Abdalah E / Alanazi, Abdulrahman F / Alotaibi, Khalid F / Alanazi, Mohammed H / Alsaeri, Amer S / Alruwaili, Meshal A / Alghamdi, Rayan S

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52508

    Abstract: Background The most frequent gynecologic cancer in women is cervical cancer. The majority of incidents take place in less developed nations without access to reliable screening tools. Human papillomavirus (HPV) exposure, smoking, and immune system ... ...

    Abstract Background The most frequent gynecologic cancer in women is cervical cancer. The majority of incidents take place in less developed nations without access to reliable screening tools. Human papillomavirus (HPV) exposure, smoking, and immune system dysfunction are risk factors. As a result of effective screening, its incidence and death have significantly decreased in many nations. Hence, this study aims to assess the level of knowledge and awareness among parents regarding HPV, including its associated health risks and the benefits of vaccination. Methodology A descriptive cross-sectional study was carried out in the Riyadh region of Saudi Arabia from September to November 2023. The main tool used for gathering data was an online, self-administered survey via Google Forms. Collected data was analysed using SPSS v. 24 (IBM Corp., Armonk, NY), where all applicable statistical tests were used. Results Females exhibited higher levels of confidence and agreement with COVID-19 and HPV vaccination recommendations compared to males. A substantial percentage of males expressed strong disagreement and reduced confidence in HPV vaccination, contributing to the gender-based divergence. Individuals with higher education levels, such as university degree graduates, showed greater support for compulsory vaccines and a preference for natural immunity development in their children. Marital status played a role in vaccine-related decisions, with variations in vaccine refusal rates and difficulty discussing the HPV vaccine noted among individuals based on their marital status. Conclusion The study highlights the value of medical experts and specifically created training programs to close knowledge gaps and boost HPV vaccination rates. Demographic factors have an impact on attitudes, which highlights the need for targeted interventions.
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Awareness About Osteoporosis Among the General Population Based on the Osteoporosis Knowledge Assessment Tool (OKAT): A Cross-Sectional Study in the Northern Border Region of Saudi Arabia.

    Elmorsy, Ekramy / Elsawi, Amgad N / Alruwaili, Nasser M / Alruwaili, Abdulelah H / Alanazi, Sultan N / Alenezi, Khalid R

    Cureus

    2024  Volume 16, Issue 3, Page(s) e56839

    Abstract: Objective: Osteoporosis is a progressive systemic skeletal disease characterized by increasing susceptibility to fractures. The current study was conducted to assess the awareness about osteoporosis among the general population in the Northern Border ... ...

    Abstract Objective: Osteoporosis is a progressive systemic skeletal disease characterized by increasing susceptibility to fractures. The current study was conducted to assess the awareness about osteoporosis among the general population in the Northern Border region of Saudi Arabia to improve awareness and proper planning for public awareness about osteoporosis.
    Methods: The study was conducted as a cross-sectional survey study, based on the online distribution of the Arabic-translated Osteoporosis Knowledge Assessment Tool (OKAT). The questionnaire questions cover the demographic characteristics of the participants, as well as symptoms, risk factors, prevention, and knowledge of treatment centers for osteoporosis in Saudi Arabia.
    Results: 395 participants were enrolled in the study after their informed consenting. After scoring all correct answers for each participant, the mean score of all participants' answers was 12.5±3.4 (range 0-19). Participants with poor knowledge (0-7 scores), moderate knowledge (8-13 scores), and good knowledge (13-20 scores) represent 61 (15.4%), 213 (53.9%), and 121 (30.6%), respectively. The mean percentage of right answers to all the questions is 44.1%. The highest awareness level was shown in the area of osteoporosis symptoms and risk of fractures, while the lowest was recorded in the questions covering the risk factors. Ages, genders, jobs, and levels of education significantly affected the participants' levels of awareness.
    Conclusion: The public awareness among the population in the Northern Border region about osteoporosis is less than satisfactory. More awareness activities targeting the risky groups should be planned especially in the area of risk factors and preventive measures for osteoporosis.
    Language English
    Publishing date 2024-03-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.56839
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evaluation of Peri-Implant Parameters and Functional Outcome of Immediately Placed and Loaded Mandibular Overdentures: A 5-year Follow-up Study.

    AlHelal, Abdulaziz A / Alzaid, Abdulaziz A / Almujel, Saad H / Alsaloum, Mohammed / Alanazi, Khalid K / Althubaitiy, Ramzi O / Al-Aali, Khulud A

    Oral health & preventive dentistry

    2024  Volume 22, Issue 1, Page(s) 23–30

    Abstract: Purpose: To evaluate the peri-implant parameters of immediately placed and loaded mandibular overdentures over a 5-year follow-up period.: Materials and methods: All subjects who had been advised and planned for two-implant mandibular overdenture ... ...

    Abstract Purpose: To evaluate the peri-implant parameters of immediately placed and loaded mandibular overdentures over a 5-year follow-up period.
    Materials and methods: All subjects who had been advised and planned for two-implant mandibular overdenture treatment were included in this study. The peri-implant parameters -including plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) as well as marginal bone loss (MBL) - were assessed. In addition, prosthodontic parameters including abutment-, implant- and denture-related complications were assessed. Patients were evaluated at follow-up visits, scheduled at 1, 12, 24, 36, 48, and 60 months. The data distribution was analysed with the Shapiro-Wilk test. Data within follow-up categories were compared using ANOVA and the Tukey-Kramer test. A p-value < 0.05 was considered statistically significant.
    Results: Among the 32 participants, 19 were males and 13 were females, with a mean age of 60.5 ± 7.33. The mean plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) varied over time. However, no statistically significant difference was observed in the plaque index, bleeding index and peri-implant pocket depth over time (p > 0.05). The mean value at baseline was found to be -0.9 ± 0.3. The values increased over time, with the highest value observed at 60 months 2.6 ± 0.7, which was statistically significant (p < 0.001).
    Conclusion: Immediately placed and loaded mandibular implant overdentures using two un-splinted implants with locator attachments showed acceptable PI, BI and PIPD at the 5-year follow-up. Statistically significantly greater marginal bone loss was observed from baseline to follow-up, but it was within acceptable limits. A moderate number of restorative and abutment complications were observed during the follow-up of IODs.
    MeSH term(s) Male ; Female ; Humans ; Middle Aged ; Aged ; Follow-Up Studies ; Denture, Overlay ; Treatment Outcome ; Alveolar Bone Loss/diagnostic imaging ; Alveolar Bone Loss/etiology ; Mandible ; Dental Implants
    Chemical Substances Dental Implants
    Language English
    Publishing date 2024-01-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2136786-3
    ISSN 1757-9996 ; 1602-1622
    ISSN (online) 1757-9996
    ISSN 1602-1622
    DOI 10.3290/j.ohpd.b4836045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Single-Anastomosis Sleeve Jejunal Bypass as a Treatment for Morbid Obesity: A Systematic Review and Meta-Analysis.

    Alenezi, Mohamad Ahmad M / Alkhaldi, Sanad Inad H / Alrumaih, Yahya Khaled I / Alzalabani, Abdullah Khalid M / Alnujaydi, Mohammed Ahmed M / Alanazi, Sultan Mohammed F / Alotibi, Fahad Abdullah J / Alanazi, Rakan Zuwayyid A / Alanazi, Malek Saad M / Alanazi, Alshaymaa Akram A

    Cureus

    2023  Volume 15, Issue 12, Page(s) e51296

    Abstract: Single-anastomosis sleeve jejunal (SASJ) bypass is a bariatric surgery technique with promising results. However, evidence of its efficacy and safety is still lacking. This study aimed to summarize the evidence regarding the efficacy and safety of SASJ ... ...

    Abstract Single-anastomosis sleeve jejunal (SASJ) bypass is a bariatric surgery technique with promising results. However, evidence of its efficacy and safety is still lacking. This study aimed to summarize the evidence regarding the efficacy and safety of SASJ bypass surgery in the treatment of morbid obesity. The literature was searched for English-language studies published from inception till November 26, 2023, on MEDLINE/PubMed, Cochrane Library, Web of Science, ProQuest, Scopus, SCINAPSE, and Google Scholar. The search terms included "morbid obesity," "bariatric surgery," and "single anastomosis sleeve jejunal bypass." Extracted data included the body mass index (BMI) before and after surgery, percent total weight loss (%TWL), percent excess weight loss (%EWL), and improvement in preoperative comorbidities. Pooling of the data was done using random effects or fixed-effect models based on the presence of significant heterogeneity. Nine studies were included in this systematic review and meta-analysis. The change in BMI from baseline at 12 months after SASJ bypass was significant (standardized mean difference (SMD) = -3.576, 95% confidence interval (CI) = -5.423, -1.730; I² = 99.23%). At 12 months after surgery, the pooled %TWL was 42.526 (95% CI = 37.948, 47.105; I² = 97.15%), and the pooled %EWL was 75.258 (95% CI = 67.061, 83.456; I² = 99.26%). The pooled incidence of postoperative improvement in diabetes mellitus was 91% (95% CI = 79.6%, 98%, I² = 82%). The overall rate of complications was 9.9% (95% CI = 2.5%, 21.6%; I² = 92.64%). Regarding the short- and mid-term outcomes, SASJ bypass is a safe and effective procedure for weight loss in patients with morbid obesity, with an acceptable rate of complications. The procedure is also associated with a marked improvement in obesity-related comorbidities.
    Language English
    Publishing date 2023-12-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Evaluation of Child Preference for Dentist Attire and Usage of a Camouflage Syringe in Reduction of Anxiety.

    Ahmad, Mohammad Shakil / Alruwaili, Abdulsalam Alshami M / Alruwaili, Khalid Hussain A / Alanazi, Abdullah Khalaf M / Alarjan, Layan Mohammed M / Alanazi, Abdulmajeed Mamdouh M / Aljunaydi, Naif Abdulrahman N / Alkhaldi, Abdulrahman Muharrab M / Alabdali, Meshari Farhan H / Alrashedi, Faisal Fraih

    Journal of pharmacy & bioallied sciences

    2024  Volume 16, Issue Suppl 1, Page(s) S757–S760

    Abstract: Objective: This study aimed to evaluate the effect of child-friendly dentist attire and camouflage syringes on reducing dental anxiety in children.: Methods: A cross-sectional study was conducted with 120 pediatric patients aged 6 to 12 years. ... ...

    Abstract Objective: This study aimed to evaluate the effect of child-friendly dentist attire and camouflage syringes on reducing dental anxiety in children.
    Methods: A cross-sectional study was conducted with 120 pediatric patients aged 6 to 12 years. Participants were assigned to one of three groups: group A (child-friendly dentist attire), group B (camouflage syringe), or group C (control group). Child preference for dentist attire was assessed using a visual analog scale, while dental anxiety was measured using the Modified Child Dental Anxiety Scale and the Facial Image Scale.
    Results: The results showed a significant decrease in dental anxiety scores in both group 2 and group 3 compared to group 1 (
    Conclusion: Child-friendly dentist attire and camouflage syringes were found to be effective in reducing dental anxiety among pediatric patients. These interventions were well received by children and their parents, highlighting the importance of considering child preferences in dental settings.
    Language English
    Publishing date 2024-01-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2573569-X
    ISSN 0975-7406 ; 0976-4879
    ISSN (online) 0975-7406
    ISSN 0976-4879
    DOI 10.4103/jpbs.jpbs_997_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Author Correction: Ultrasensitive and selective molecularly imprinted electrochemical oxaliplatin sensor based on a novel nitrogen-doped carbon nanotubes/Ag@cu MOF as a signal enhancer and reporter nanohybrid.

    Mahnashi, Mater H / Mahmoud, Ashraf M / Alhazzani, Khalid / Alanazi, A Z / Alaseem, Ali Mohammed / Algahtani, Mohammad M / El-Wekil, Mohamed M

    Mikrochimica acta

    2023  Volume 190, Issue 6, Page(s) 227

    Language English
    Publishing date 2023-05-18
    Publishing country Austria
    Document type Published Erratum
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-023-05810-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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