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  1. Book ; Online: Type 2 Diabetes

    Pantea Stoian, Anca

    From Pathophysiology to Cyber Systems

    2021  

    Keywords Endocrinology ; diabetes mellitus, insulin resistance, metabolic syndrome, type 2 diabetes mellitus, oxidative stress, machine learning
    Language English
    Size 1 electronic resource (440 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030646723
    ISBN 9781838819057 ; 1838819053
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Metformin

    Mihaela Pantea Stoian, Anca / Rizzo, Manfredi

    2020  

    Keywords Pharmacology
    Size 1 electronic resource (242 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021049379
    ISBN 9781838807603 ; 1838807608
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Lipoprotein subclasses and early kidney dysfunction in young type 1 diabetes mellitus patients.

    Vekic, Jelena / Stoian, Anca Pantea / Rizzo, Manfredi

    Journal of diabetes and its complications

    2023  Volume 37, Issue 3, Page(s) 108412

    MeSH term(s) Humans ; Diabetes Mellitus, Type 1 ; Lipoproteins ; Lipoproteins, HDL ; Kidney
    Chemical Substances Lipoproteins ; Lipoproteins, HDL
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1105840-7
    ISSN 1873-460X ; 1056-8727
    ISSN (online) 1873-460X
    ISSN 1056-8727
    DOI 10.1016/j.jdiacomp.2023.108412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Glucagon-like peptide-1 receptor agonists for improving cardiorenal outcomes in type 1 diabetes mellitus?

    Popovic, Djordje S / Stoian, Anca Pantea / Papanas, Nikolaos

    Endocrine

    2023  Volume 80, Issue 1, Page(s) 232–233

    MeSH term(s) Humans ; Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/drug therapy ; Glucagon-Like Peptide-1 Receptor/agonists ; Hypoglycemic Agents/therapeutic use
    Chemical Substances Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1194484-5
    ISSN 1559-0100 ; 1355-008X ; 0969-711X
    ISSN (online) 1559-0100
    ISSN 1355-008X ; 0969-711X
    DOI 10.1007/s12020-022-03294-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Editorial: Diet-microbe-host interactions in metabolic syndrome.

    Gradisteanu Pircalabioru, Gratiela / Rizzo, Manfredi / Pantea Stoian, Anca / Chifiriuc, Mariana Carmen

    Frontiers in nutrition

    2023  Volume 10, Page(s) 1129200

    Language English
    Publishing date 2023-01-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2023.1129200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Tirzepatide and glucagon-like peptide-1 receptor agonists: safety always comes first!

    Patoulias, Dimitrios / Caprio, Massimiliano / Stoian, Anca Pantea / Rizzo, Manfredi

    Expert opinion on drug safety

    2023  Volume 22, Issue 9, Page(s) 763–765

    MeSH term(s) Humans ; Glucagon-Like Peptide-1 Receptor ; Gastric Inhibitory Polypeptide ; Diabetes Mellitus, Type 2 ; Hypoglycemic Agents/adverse effects
    Chemical Substances tirzepatide (OYN3CCI6QE) ; Glucagon-Like Peptide-1 Receptor ; Gastric Inhibitory Polypeptide (59392-49-3) ; Hypoglycemic Agents
    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Editorial
    ZDB-ID 2088728-0
    ISSN 1744-764X ; 1474-0338
    ISSN (online) 1744-764X
    ISSN 1474-0338
    DOI 10.1080/14740338.2023.2247984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Could cardiorenal benefits of sodium-glucose co-transporter 2 inhibitors be extended to type 1 diabetes mellitus?

    Popovic, Djordje S / Stoian, Anca Pantea / Papanas, Nikolaos

    Journal of diabetes and its complications

    2022  Volume 36, Issue 11, Page(s) 108338

    MeSH term(s) Humans ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/drug therapy ; Sodium-Glucose Transporter 2 ; Hypoglycemic Agents/therapeutic use ; Hypoglycemic Agents/pharmacology ; Glucose ; Sodium
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors ; Sodium-Glucose Transporter 2 ; Hypoglycemic Agents ; Glucose (IY9XDZ35W2) ; Sodium (9NEZ333N27)
    Language English
    Publishing date 2022-10-10
    Publishing country United States
    Document type Letter
    ZDB-ID 1105840-7
    ISSN 1873-460X ; 1056-8727
    ISSN (online) 1873-460X
    ISSN 1056-8727
    DOI 10.1016/j.jdiacomp.2022.108338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Interactions between Gut Microbiota and Oral Antihyperglycemic Drugs: A Systematic Review.

    Mindrescu, Nicoleta Mihaela / Guja, Cristian / Jinga, Viorel / Ispas, Sorina / Curici, Antoanela / Nelson Twakor, Andreea / Pantea Stoian, Anca Mihaela

    International journal of molecular sciences

    2024  Volume 25, Issue 6

    Abstract: The intestinal microbiota refers to the collection of microorganisms that exist in the human gut. It has been said that bacteria influence the development of metabolic diseases, such as diabetes mellitus, as they have roles in immunomodulation, ... ...

    Abstract The intestinal microbiota refers to the collection of microorganisms that exist in the human gut. It has been said that bacteria influence the development of metabolic diseases, such as diabetes mellitus, as they have roles in immunomodulation, protection against pathogens, blood vessel growth, repairing the intestinal wall, and the development of the neurological system. In this review, we look at the latest research regarding interactions between gut microbiota and oral antihyperglycemic drugs and we present data suggesting that the microbiome may help counteract the reduced glucose tolerance and insulin resistance associated with metabolic disorders. We found that antidiabetic drugs can have significant impacts on gut microbiota composition and function, potentially influencing both the efficacy and side effects of these medications. Additionally, we discovered that microbial-based therapeutics, including probiotics, prebiotics, and postbiotics, and fecal microbiota can be considered when discussing preventive measures and personalized treatment options for type 2 diabetes mellitus. Understanding how antidiabetic drugs modulate gut microbiota composition and function is essential for optimizing their therapeutic efficacy and minimizing potential adverse effects. The relationship between the gut microbiota and glycemic agents, not fully understood, is currently the subject of increasing research and discussion. It has been proven that the microbiome can impact the effectiveness of the medications, but further research in this field may uncover novel therapeutic strategies for diabetes and other metabolic disorders by targeting the gut microbiota.
    MeSH term(s) Humans ; Gastrointestinal Microbiome ; Diabetes Mellitus, Type 2/metabolism ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Intestines/microbiology ; Prebiotics ; Probiotics/therapeutic use
    Chemical Substances Hypoglycemic Agents ; Prebiotics
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25063540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Skin Autofluorescence as a Potential Adjunctive Marker for Cardiovascular Risk Assessment in Type 2 Diabetes: A Systematic Review.

    Reurean-Pintilei, Delia / Pantea Stoian, Anca / Potcovaru, Claudia-Gabriela / Salmen, Teodor / Cinteză, Delia / Stoica, Roxana-Adriana / Lazăr, Sandra / Timar, Bogdan

    International journal of molecular sciences

    2024  Volume 25, Issue 7

    Abstract: Diabetes mellitus (DM), due to its long-term hyperglycemia, leads to the accumulation of advanced glycation end-products (AGEs), especially in the vessel walls. Skin autofluorescence (SAF) is a non-invasive tool that measures AGEs. DM patients have a ... ...

    Abstract Diabetes mellitus (DM), due to its long-term hyperglycemia, leads to the accumulation of advanced glycation end-products (AGEs), especially in the vessel walls. Skin autofluorescence (SAF) is a non-invasive tool that measures AGEs. DM patients have a rich dietary source in AGEs, associated with high oxidative stress and long-term inflammation. AGEs represent a cardiovascular (CV) risk factor, and they are linked with CV events. Our objective was to assess whether SAF predicts future CV events (CVE) by examining its association with other CV risk factors in patients with type 2 DM (T2DM). Additionally, we assessed the strengths and limitations of SAF as a predictive tool for CVE. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology, we conducted a systematic review with CRD42024507397 protocol, focused on AGEs, T2DM, SAF, and CV risk. We identified seven studies from 2014 to 2024 that predominantly used the AGE Reader Diagnostic Optic tool. The collective number of patients involved is 8934, with an average age of 63. So, SAF is a valuable, non-invasive marker for evaluating CV risk in T2DM patients. It stands out as a CV risk factor associated independently with CVE. SAF levels are influenced by prolonged hyperglycemia, lifestyle, aging, and other chronic diseases such as depression, and it can be used as a predictive tool for CVE.
    MeSH term(s) Humans ; Middle Aged ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/etiology ; Risk Factors ; Diabetes Mellitus, Type 2/complications ; Heart Disease Risk Factors ; Hyperglycemia
    Language English
    Publishing date 2024-03-31
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25073889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Associations between Skin Autofluorescence Levels with Cardiovascular Risk and Diabetes Complications in Patients with Type 2 Diabetes.

    Reurean-Pintilei, Delia / Pantea Stoian, Anca / Salmen, Teodor / Stoica, Roxana-Adriana / Mititelu-Tartau, Liliana / Lazăr, Sandra / Timar, Bogdan

    Biomedicines

    2024  Volume 12, Issue 4

    Abstract: Advanced Glycation End Products (AGEs) contribute to the pathophysiology of type 2 diabetes mellitus (T2DM) and cardiovascular (CV) diseases (CVDs), making their non-invasive assessment through skin autofluorescence (SAF) increasingly important. This ... ...

    Abstract Advanced Glycation End Products (AGEs) contribute to the pathophysiology of type 2 diabetes mellitus (T2DM) and cardiovascular (CV) diseases (CVDs), making their non-invasive assessment through skin autofluorescence (SAF) increasingly important. This study aims to investigate the relationship between SAF levels, cardiovascular risk, and diabetic complications in T2DM patients. We conducted a single-center, cross-sectional study at Consultmed Hospital in Iasi, Romania, including 885 T2DM patients. The assessment of SAF levels was performed with the AGE Reader™, (Diagnoptics, Groningen, The Netherlands). CVD prevalence was 13.9%, and according to CV risk category distribution, 6.1% fell into the moderate-risk, 1.13% into the high-risk, and 92.77% into the very-high-risk category. The duration of DM averaged 9.0 ± 4.4 years and the mean HbA1c was 7.1% ± 1.3. After adjusting for age and eGFR, HbA1c values showed a correlation with SAF levels in the multivariate regression model, where a 1 SD increase in HbA1c was associated with a 0.105 SD increase in SAF levels (Nagelkerke R
    Language English
    Publishing date 2024-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12040890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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