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Article ; Online: Type 2 Diabetes.

Vijan, Sandeep

2020 Volume 172, Issue 10, Page(s) 705

MeSH term(s)	Diabetes Mellitus, Type 1 ; Diabetes Mellitus, Type 2 ; Humans
Language	English
Publishing date	2020-05-18
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/L20-0012
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Article ; Online: Type 2 Diabetes.

Vijan, Sandeep

Annals of internal medicine

2019 Volume 171, Issue 9, Page(s) ITC65–ITC80

Abstract: Type 2 diabetes is a prevalent illness that causes major vascular, renal, and neurologic complications. Prevention and treatment of diabetes and its complications are of paramount importance. Many new treatments have emerged over the past 5-10 years. ... ...

Abstract	Type 2 diabetes is a prevalent illness that causes major vascular, renal, and neurologic complications. Prevention and treatment of diabetes and its complications are of paramount importance. Many new treatments have emerged over the past 5-10 years. Recent evidence shows that newer treatments may substantially reduce risk for cardiac and renal disease, suggesting that it may be necessary to change existing treatment paradigms. This review summarizes the evidence supporting diabetes prevention and treatment, focusing on aspects that are commonly in the purview of primary care physicians.
MeSH term(s)	Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/therapy ; Disease Management ; Global Health ; Humans ; Kidney Diseases/epidemiology ; Kidney Diseases/etiology ; Kidney Diseases/prevention & control ; Mass Screening/methods ; Morbidity/trends ; Risk Factors
Language	English
Publishing date	2019-11-04
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/AITC201911050
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Type 2 diabetes.

Vijan, Sandeep

Annals of internal medicine

2015 Volume 163, Issue 4, Page(s) 322

MeSH term(s)	Diabetes Mellitus, Type 2 ; Humans
Language	English
Publishing date	2015-08-18
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/L15-5122-2
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Article ; Online: In the clinic. Type 2 diabetes.

Vijan, Sandeep

Annals of internal medicine

2015 Volume 162, Issue 5, Page(s) ITC1–16

Abstract: This issue provides a clinical overview of Type 2 Diabetes focusing on prevention, diagnosis, treatment, practice improvement, and patient information. The content of In the Clinic is drawn from the clinical information and education resources of the ... ...

Abstract	This issue provides a clinical overview of Type 2 Diabetes focusing on prevention, diagnosis, treatment, practice improvement, and patient information. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including ACP Smart Medicine and MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic from these primary sources in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of science writers and physician writers. Editorial consultants from ACP Smart Medicine and MKSAP provide expert review of the content. Readers who are interested in these primary resources for more detail can consult http://smartmedicine.acponline.org, http://mksap.acponline.org, and other resources referenced in each issue of In the Clinic.
MeSH term(s)	Blood Glucose Self-Monitoring ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/prevention & control ; Diabetes Mellitus, Type 2/therapy ; Diet, Diabetic ; Exercise Therapy ; Humans ; Hypoglycemic Agents/therapeutic use ; Mass Screening ; Patient Education as Topic ; Risk Factors
Chemical Substances	Hypoglycemic Agents
Language	English
Publishing date	2015-03-03
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/AITC201503030
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diabetes: treating hypertension.

Vijan, Sandeep

BMJ clinical evidence

2014 Volume 2014

Abstract: Introduction: Between 2007 and 2010, the age-adjusted prevalence of hypertension in US adults with diabetes was 59%, more than double the prevalence in those without diabetes. Major cardiac events occur in approximately 5% of people with diabetes and ... ...

Abstract	Introduction: Between 2007 and 2010, the age-adjusted prevalence of hypertension in US adults with diabetes was 59%, more than double the prevalence in those without diabetes. Major cardiac events occur in approximately 5% of people with diabetes and untreated hypertension each year, and the risk is higher in those with other risk factors, such as diabetic nephropathy. Methods and outcomes: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of different blood pressure targets in people with diabetes and hypertension? We searched: Medline, Embase, The Cochrane Library, and other important databases up to October 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results: We found 10 studies that met our inclusion criteria. Conclusions: In this systematic review, we present information relating to the effectiveness and safety of the following intervention: more intensive (lower) blood pressure targets versus less intensive (higher) targets in people with diabetes and hypertension.
MeSH term(s)	Antihypertensive Agents/therapeutic use ; Blood Pressure ; Diabetes Complications/complications ; Humans ; Hypertension/complications ; Hypertension/drug therapy ; Risk Factors
Chemical Substances	Antihypertensive Agents
Language	English
Publishing date	2014-06-26
Publishing country	England
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	2393858-4
ISSN	1752-8526 ; 1757-0816 ; 1475-9225
ISSN (online)	1752-8526
ISSN	1757-0816 ; 1475-9225
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Retrospective multi-center study of robotic-assisted cholecystectomy: after-hours surgery and business-hours surgery outcomes.

Choudhry, Vineet / Patel, Yogesh K / McIntosh, Bruce B / Badrudduja, Mustafa / Jandali, Majed / Vijan, Sandeep / Brown, Kayla

Journal of robotic surgery

2024 Volume 18, Issue 1, Page(s) 48

Abstract: The effect of robotic-assisted cholecystectomy (RAC), when performed after hours, on perioperative outcomes has not been evaluated against outcomes achieved during normal business hours. Subjects 18-80 years old who underwent da Vinci robotic-assisted ... ...

Abstract	The effect of robotic-assisted cholecystectomy (RAC), when performed after hours, on perioperative outcomes has not been evaluated against outcomes achieved during normal business hours. Subjects 18-80 years old who underwent da Vinci robotic-assisted cholecystectomy from August 2018 to February 2021 were included. Baseline and 30-day perioperative outcomes were retrospectively and consecutively collected and analyzed. Inverse probability treatment weighting (IPTW) was performed to balance patient characteristics between groups. A weighted comparative analysis was followed. Outcomes from 505 patients (after hours, n = 169; business hours, n = 336) undergoing RAC across 5 U.S. medical institutions were analyzed. The higher rates of acute cholecystitis and gallbladder inflammation, gangrene, and intraoperative abnormalities in the after-hours group were associated with higher rates of urgent cases and longer operative times-but not increased complication rates-compared to the business-hours group. There were no significant differences in rates of intraoperative or postoperative complications, readmissions, or reoperations. Integrated da Vinci Firefly fluorescence imaging system was used extensively, and the critical view of safety was achieved in > 96% of cases in both groups. No conversions occurred in the after-hours group compared to four conversions in the business-hours group (p = 0.0266). After-hours patients had shorter outpatient lengths of stay. No mortalities were reported for either group (p = 0.0139). After-hours RAC with integrated da Vinci Firefly imaging performed by surgeons experienced in RAC is associated with similar or improved outcomes than the same procedures during business hours in terms of complications, conversions, readmissions, reoperations, and length of stay. ClinicalTrials.gov identifier: NCT04551820; August 5, 2020.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Humans ; Middle Aged ; Young Adult ; Cholecystectomy/methods ; Operative Time ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Retrospective Studies ; Robotic Surgical Procedures/methods ; Treatment Outcome
Language	English
Publishing date	2024-01-20
Publishing country	England
Document type	Clinical Study ; Journal Article ; Multicenter Study
ZDB-ID	2268283-1
ISSN	1863-2491 ; 1863-2483
ISSN (online)	1863-2491
ISSN	1863-2483
DOI	10.1007/s11701-023-01765-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diabetes: treating hypertension.

Vijan, Sandeep

American family physician

2013 Volume 87, Issue 8, Page(s) 574–575

MeSH term(s)	Aged ; Antihypertensive Agents/adverse effects ; Antihypertensive Agents/classification ; Antihypertensive Agents/pharmacokinetics ; Blood Pressure/drug effects ; Blood Pressure Determination/methods ; Blood Pressure Determination/standards ; Comorbidity ; Diabetes Complications/epidemiology ; Diabetes Complications/prevention & control ; Humans ; Hypertension/drug therapy ; Hypertension/epidemiology ; Hypertension/etiology ; Middle Aged ; Prevalence ; Prognosis ; Risk Factors ; Treatment Outcome
Chemical Substances	Antihypertensive Agents
Language	English
Publishing date	2013-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	412694-4
ISSN	1532-0650 ; 0002-838X ; 0572-3612
ISSN (online)	1532-0650
ISSN	0002-838X ; 0572-3612
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diabetes: treating hypertension.

Vijan, Sandeep

BMJ clinical evidence

2012 Volume 2012

Abstract: Introduction: Among people with diabetes, about 40% of those aged 45 years, and more than 60% of those aged 75 years or over, will have a blood pressure over 140/90 mmHg. Major cardiac events occur in approximately 5% of people with diabetes and ... ...

Abstract	Introduction: Among people with diabetes, about 40% of those aged 45 years, and more than 60% of those aged 75 years or over, will have a blood pressure over 140/90 mmHg. Major cardiac events occur in approximately 5% of people with diabetes and untreated hypertension each year, and the risk is higher in those with other risk factors, such as diabetic nephropathy. Methods and outcomes: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of antihypertensives in people with diabetes and hypertension? What are the effects of different blood pressure targets in people with diabetes and hypertension? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2011 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results: We found 24 systematic reviews, RCTs, or observational studies that met our inclusion criteria. Conclusions: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: alpha-blockers, angiotensin II receptor antagonists, angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, blood pressure targets (lower or higher), calcium-channel blockers, and diuretics.
MeSH term(s)	Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Antihypertensive Agents ; Blood Pressure/drug effects ; Calcium Channel Blockers/pharmacology ; Humans ; Hypertension/chemically induced
Chemical Substances	Angiotensin-Converting Enzyme Inhibitors ; Antihypertensive Agents ; Calcium Channel Blockers
Language	English
Publishing date	2012-03-28
Publishing country	England
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	2393858-4
ISSN	1752-8526 ; 1757-0816 ; 1475-9225
ISSN (online)	1752-8526
ISSN	1757-0816 ; 1475-9225
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: In the clinic. Type 2 diabetes.

Vijan, Sandeep

Annals of internal medicine

2010 Volume 152, Issue 5, Page(s) ITC31–15; quiz ITC316

Abstract: This issue provides a clinical overview of type 2 diabetes focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual ... ...

Abstract	This issue provides a clinical overview of type 2 diabetes focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual subscribers can access the electronic features of In the Clinic. Non-subscribers who wish to access this issue of In the Clinic can elect "Pay for View." Subscribers can receive 1.5 category 1 CME credits by completing the CME quiz that accompanies this issue of In the Clinic. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including PIER (Physicians' Information and Education Resource) and MKSAP (Medical Knowledge and Self Assessment Program). Annals of Internal Medicine editors develop In the Clinic from these primary sources in collaboration with the ACP's Medical Education and Publishing division and with assistance of science writers and physician writers. Editorial consultants from PIER and MKSAP provide expert review of the content. Readers who are interested in these primary resources for more detail can consult www.acponline.org, http://pier.acponline.org, and other resources referenced within each issue of In the Clinic.
MeSH term(s)	Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/prevention & control ; Diabetes Mellitus, Type 2/therapy ; Exercise Therapy ; Feeding Behavior ; Humans ; Hypoglycemic Agents/therapeutic use ; Mass Screening ; Quality of Health Care ; United States
Chemical Substances	Hypoglycemic Agents
Language	English
Publishing date	2010-03-02
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/0003-4819-152-5-201003020-01003
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Article ; Online: Cost-Effectiveness of Bridging Anticoagulation Among Patients with Nonvalvular Atrial Fibrillation.

Pappas, Matthew A / Barnes, Geoffrey D / Vijan, Sandeep

Journal of general internal medicine

2019 Volume 34, Issue 4, Page(s) 583–590

Abstract: Background: Bridging anticoagulation is commonly prescribed to patients with atrial fibrillation during initiation and interruption of warfarin. Guidelines recommend bridging patients at high risk of stroke, while a recent randomized trial demonstrated ... ...

Abstract	Background: Bridging anticoagulation is commonly prescribed to patients with atrial fibrillation during initiation and interruption of warfarin. Guidelines recommend bridging patients at high risk of stroke, while a recent randomized trial demonstrated overall harm in a population at comparatively low risk of ischemic stroke. Theory suggests that patients at high risk of stroke and low risk of hemorrhage may benefit from bridging, but data informing patient selection are scant. Objective: To estimate the utility and cost-effectiveness of bridging anticoagulation among patients with nonvalvular atrial fibrillation, stratified by thromboembolic and hemorrhagic risk DESIGN: Cost-effectiveness analysis with lifelong time horizon, from the perspective of a third-party payer MAIN MEASURES: Quality-adjusted life years (QALYs) per bridged patient; US dollars per QALY gained KEY RESULTS: Unselected patients with nonvalvular atrial fibrillation may be harmed by bridging anticoagulation. Hospital admission for bridging is almost never cost-effective, and generally harmful. Among patients carefully selected by both thromboembolic and hemorrhagic risks, outpatient bridging can be beneficial and cost-effective. Results were sensitive to how effectively heparin products reduce stroke risk. Conclusions: Outpatient bridging anticoagulation can be beneficial and cost-effective for a subset of patients with nonvalvular atrial fibrillation during interruption or initiation of warfarin. Admission for bridging should be avoided.
MeSH term(s)	Anticoagulants/economics ; Anticoagulants/therapeutic use ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/economics ; Blood Coagulation/drug effects ; Cost-Benefit Analysis ; Databases, Factual ; Humans ; Quality-Adjusted Life Years ; Risk Assessment ; Stroke/prevention & control
Chemical Substances	Anticoagulants
Language	English
Publishing date	2019-01-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	639008-0
ISSN	1525-1497 ; 0884-8734
ISSN (online)	1525-1497
ISSN	0884-8734
DOI	10.1007/s11606-018-4796-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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