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Article ; Online: Uncovering the inhibitory potentials of

Johnson, Titilayo Omolara / Adegboyega, Abayomi Emmanuel / Johnson, Grace I / Umedum, Ngozi L / Bamidele, Olasunkanmi D / Elekan, Ayodele O / Tarkaa, Christopher T / Mahe, Asma'u / Abdulrahman, Adamu / Adeyemi, Olugbenga E / Okafor, Desmond / Yusuf, Amina J / Atewolara-Odule, Odunayo C / Ogunmoye, Abdulrazaq O / Ishaya, Tanko

Journal of biomolecular structure & dynamics

2022 Volume 41, Issue 19, Page(s) 9787–9796

Abstract: Malaria control efforts have been hampered due to the emergence of resistant malaria parasite strains and the coinciding events of Covid-19. The quest for more effective and safe treatment alternatives is driving a slew of new studies that must be ... ...

Abstract	Malaria control efforts have been hampered due to the emergence of resistant malaria parasite strains and the coinciding events of Covid-19. The quest for more effective and safe treatment alternatives is driving a slew of new studies that must be accelerated if malaria can be overcome. Due to its reported antimalarial activity, we studied the effects of extract and fractions of
MeSH term(s)	Mice ; Animals ; L-Lactate Dehydrogenase ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Malaria/drug therapy ; Malaria/parasitology ; Antimalarials/chemistry ; Chloroquine/pharmacology ; Plasmodium berghei ; Plasmodium falciparum
Chemical Substances	ethyl acetate (76845O8NMZ) ; L-Lactate Dehydrogenase (EC 1.1.1.27) ; Plant Extracts ; Antimalarials ; Chloroquine (886U3H6UFF)
Language	English
Publishing date	2022-11-21
Publishing country	England
Document type	Journal Article
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2022.2146750
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Article ; Online: Burden of chronic kidney disease: an international perspective.

Ayodele, Olugbenga E / Alebiosu, C Olutayo

Advances in chronic kidney disease

2010 Volume 17, Issue 3, Page(s) 215–224

Abstract: CKD is associated with increased cardiovascular mortality and a loss of disability-adjusted life years. Diseases of the genitourinary system were responsible for 928,000 deaths and 14,754,000 disability-adjusted life years in 2004. However, the absence ... ...

Abstract	CKD is associated with increased cardiovascular mortality and a loss of disability-adjusted life years. Diseases of the genitourinary system were responsible for 928,000 deaths and 14,754,000 disability-adjusted life years in 2004. However, the absence of kidney registries in most of the low- and middle-income countries has made it difficult to ascertain the true burden of CKD in these countries. The global increase in the incidence and prevalence of CKD is being driven by the global increase in the prevalence of diabetes mellitus, hypertension, obesity, and aging. Most patients in low- and middle-income countries die because they cannot access renal replacement therapy because of the exorbitant cost. Community surveys have shown that the number of people with end-stage kidney disease is just the tip of the "CKD iceberg." The preventive strategies to stem the tide of CKD should involve educating the population on how to prevent renal disease; identifying those at risk of developing CKD; raising the awareness of the general public, policy makers, and health care workers; modifying the lifestyle of susceptible individuals; detecting early stage of CKD; arresting or hindering the progression of disease; and creating facilities for global assistance.
MeSH term(s)	Chronic Disease ; Cost of Illness ; Early Diagnosis ; Humans ; Incidence ; Internationality ; Kidney Diseases/epidemiology ; Kidney Diseases/etiology ; Kidney Diseases/physiopathology ; Kidney Diseases/prevention & control ; Kidney Failure, Chronic/epidemiology ; Prevalence ; Risk Factors
Language	English
Publishing date	2010-05
Publishing country	United States
Document type	Journal Article
ISSN	1548-5609 ; 1548-5595
ISSN (online)	1548-5609
ISSN	1548-5595
DOI	10.1053/j.ackd.2010.02.001
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Article ; Online: Urinary Transforming Growth Factor-Beta 1 (uTGF-β1) and Prevalent CKD Risk in HIV-Positive Patients in West Africa.

Ekrikpo, Udeme E / Okuku, Cecilia N / Ajayi, Samuel O / Ayodele, Olugbenga E / Bello, Aminu K / Wonkam, Ambroise / Dandara, Collet / Kengne, Andre-Pascal / Okpechi, Ikechi

Kidney international reports

2019 Volume 4, Issue 12, Page(s) 1698–1704

Abstract: Introduction: This study investigated the association of urinary transforming growth factor-β1 (uTGF-β1) with prevalent chronic kidney disease (CKD) in the HIV-infected population.: Methods: HIV-positive patients without CKD (HIV: Results: The age ...

Abstract	Introduction: This study investigated the association of urinary transforming growth factor-β1 (uTGF-β1) with prevalent chronic kidney disease (CKD) in the HIV-infected population. Methods: HIV-positive patients without CKD (HIV Results: The age of the participants was 38.3 ± 10.3 years with 73.4% women. The median uTGF-β1Cr was higher among HIV Conclusion: HIV
Language	English
Publishing date	2019-07-27
Publishing country	United States
Document type	Journal Article
ISSN	2468-0249
ISSN (online)	2468-0249
DOI	10.1016/j.ekir.2019.07.011
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Article ; Online: Long-term renal outcome and complications in South Africans with proliferative lupus nephritis.

Ayodele, Olugbenga E / Okpechi, Ikechi G / Swanepoel, Charles R

International urology and nephrology

2013 Volume 45, Issue 5, Page(s) 1289–1300

Abstract: Aim: To report the long-term outcome and complication profile of South African patients with proliferative lupus nephritis (PLN).: Methods: A retrospective review of 66 patients with biopsy-proven PLN [58 diffuse proliferative LN (Class IV) and 8 ... ...

Abstract	Aim: To report the long-term outcome and complication profile of South African patients with proliferative lupus nephritis (PLN). Methods: A retrospective review of 66 patients with biopsy-proven PLN [58 diffuse proliferative LN (Class IV) and 8 focal proliferative LN (Class III)] under our care from January 1995 to December 2009 was done. Results: Thirty-three (50 %) patients reached the composite end point of doubling of serum creatinine, end-stage renal disease (ESRD) or death. The 5-, 10- and 15-year cumulative event-free survival rates were 54, 34 and 27 %, respectively. Variables associated with the composite end point were simultaneous diagnosis of SLE and LN (p = 0.048); elevated serum creatinine at onset (p = 0.009); elevated systolic blood pressure (SBP) (p < 0.001) and elevated diastolic blood pressure (DBP) (p < 0.001) on follow-up; and non-remission following induction therapy (p < 0.001). The 5-, 10- and 15-year renal survival rates in our patients were 63, 52 and 52 %, respectively. Hypertension at onset of LN (p = 0.037), nephrotic-range proteinuria (p = 0.033), eGFR < 60 ml/min/1.73 m(2) (p = 0.013) and lack of remission following induction therapy (p < 0.001) were all associated with development of end-stage renal disease (ESRD). Elevated SBP on follow-up (95 % CI 1.03-1.34, p = 0.017) was the only factor associated with composite end point while failure to achieve remission following induction therapy was the only factor associated with ESRD on multivariate analysis. Thirty-five (53 %) patients developed complications with persistent leukopenia, gastritis, sepsis, tuberculosis (TB) and herpes zoster being the leading complications. Ovarian failure occurred in 4 (11 %) patients. Conclusion: The 5-, 10 and 15-year event-free survival rates were 54, 34 and 27 % and failure to achieve remission following induction therapy predicted poor renal survival on multivariate analysis.
MeSH term(s)	Adult ; Anti-Inflammatory Agents/therapeutic use ; Azathioprine/therapeutic use ; Blood Pressure ; Creatinine/blood ; Cyclophosphamide/therapeutic use ; Disease Progression ; Disease-Free Survival ; Female ; Glomerular Filtration Rate ; Humans ; Hypertension/complications ; Immunosuppressive Agents/therapeutic use ; Kidney Failure, Chronic/etiology ; Lupus Nephritis/complications ; Lupus Nephritis/drug therapy ; Lupus Nephritis/pathology ; Male ; Methylprednisolone/therapeutic use ; Prednisone/therapeutic use ; Proteinuria/etiology ; Remission Induction ; Retrospective Studies ; Risk Assessment ; Risk Factors ; South Africa ; Survival Rate ; Time Factors ; Treatment Failure ; Young Adult
Chemical Substances	Anti-Inflammatory Agents ; Immunosuppressive Agents ; Cyclophosphamide (8N3DW7272P) ; Creatinine (AYI8EX34EU) ; Azathioprine (MRK240IY2L) ; Prednisone (VB0R961HZT) ; Methylprednisolone (X4W7ZR7023)
Language	English
Publishing date	2013-01-10
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	204048-7
ISSN	1573-2584 ; 0301-1623 ; 0042-1162
ISSN (online)	1573-2584
ISSN	0301-1623 ; 0042-1162
DOI	10.1007/s11255-012-0376-9
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Article: Acute kidney injury requiring hemodialysis in the tropics.

Okunola, Oluyomi O / Ayodele, Olugbenga E / Adekanle, Adebode D

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

2012 Volume 23, Issue 6, Page(s) 1315–1319

Abstract: ... were in ARF, i.e. stage 3 AKI requiring hemodialysis. There were 24 males and 21 females. The most ...

Abstract	The morbidity and mortality from acute kidney injury (AKI) have remained relatively high over the last six decades. The triad of infections, nephrotoxins and obstetric complications are still major causes of acute kidney injury in the tropics. This retrospective study is a five-year audit of acute renal failure (ARF) (or stage 3 AKI) in patients requiring hemodialysis at the renal unit of the Department of Medicine of the Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Osogbo, Nigeria. A total of 80 patients with AKI were treated over a five-year period at our center, of which 45 (56.2%) were in ARF, i.e. stage 3 AKI requiring hemodialysis. There were 24 males and 21 females. The most common cause of ARF among the patients was sepsis syndrome 16 (35.5%), while pregnancy-related cases accounted for 15 (33.3%) and nephrotoxins for 6 (13.3%). Five (33%) of the 15 pregnancy-related patients survived, and all were cases of septic abortion. Of the other 10 patients that did not survive, three (30%) had post-partum hemorrhage and seven (70%) post-partum eclampsia. In all, the mortality rate among our AKI presenting for hemodialysis at our center over a given year period was 28.8%. Majority of these were eclampsia related. The causes of ARF still remain the same in the tropics, eclampsia portends poor prognosis. Concerted efforts should be made at limiting this trend by active preventive services and early recognition of high-risk obstetrics cases.
MeSH term(s)	Abortion, Septic/etiology ; Acute Kidney Injury/etiology ; Acute Kidney Injury/mortality ; Acute Kidney Injury/therapy ; Adolescent ; Adult ; Aged ; Eclampsia/etiology ; Female ; Hospitals, University ; Humans ; Male ; Middle Aged ; Nigeria/epidemiology ; Postpartum Hemorrhage/etiology ; Pregnancy ; Pregnancy Complications/etiology ; Pregnancy Complications/mortality ; Pregnancy Complications/therapy ; Renal Dialysis/adverse effects ; Renal Dialysis/mortality ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Systemic Inflammatory Response Syndrome/complications ; Time Factors ; Treatment Outcome ; Tropical Climate ; Young Adult
Language	English
Publishing date	2012-11
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	1379955-1
ISSN	1319-2442
ISSN	1319-2442
DOI	10.4103/1319-2442.103587
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Zs.A 4735: Show issues

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Article ; Online: Spectrum of skin diseases presented at LAUTECH Teaching Hospital, Osogbo, southwest Nigeria.

Akinboro, Adeolu O / Mejiuni, Ayodele D / Akinlade, Mathias O / Audu, Bosede M / Ayodele, Olugbenga E

International journal of dermatology

2015 Volume 54, Issue 4, Page(s) 443–450

Abstract: Background: Patterns of skin disease in developing nations are changing as frequencies of non-communicable diseases continue to increase. Appraisal of the current status of the disease profile is of utmost importance for health planning and resource ... ...

Abstract	Background: Patterns of skin disease in developing nations are changing as frequencies of non-communicable diseases continue to increase. Appraisal of the current status of the disease profile is of utmost importance for health planning and resource allocation. Methods: A prospective analysis of 895 cases of outpatient consultation during the years 2005-2010 was conducted. Results: The mean ± standard deviation age of patients was 31.1 ± 19.1 years. Non-infectious skin diseases accounted for 80.9% of all cases. Eczemas/dermatitis (27.0%), urticarias/erythemas (11.0%), fungal infections (9.5%), skin appendage disorders (8.9%), papulosquamous diseases (8.2%), pigmentary diseases (8.2%), viral infections (6.8%), and tumors and malignant skin lesions (5.4%) represented the most common presentations. Atopic dermatitis was the most common type of eczema (29.8%) among children (odds ratio [OR] 1.53, 95% confidence interval [CI] 1.09-2.13; P = 0.013), in whom cornification disorders (OR 3.90, 95% CI 1.73-8.92; P < 0.001) and viral infections (OR 1.80, 95% CI 1.09-3.25; P = 0.021) were also frequent. Adults were more likely to be diagnosed with drug eruptions (OR 3.58, 95% CI 1.09-11.80; P = 0.003), tumors/malignancy (OR 4.97, 95% CI 1.53-16.10; P = 0.030), or autoimmune connective tissue disorders (OR 8.13, 95% CI 1.09-60.20; P = 0.015). Female subjects were significantly affected by urticarias (OR 1.53, 95% CI 1.00-2.33; P = 0.030) and papulosquamous diseases (OR 1.80, 95% CI 1.09-3.03; P = 0.019). Conclusions: The present pattern shows that non-infectious skin diseases are predominant. Occurrences of eczemas and urticarias are increasing at similar rates, whereas infectious skin diseases are decreasing in frequency. Resources and research should be directed towards the prevention of non-infectious skin diseases at this time as the campaign for a cleaner environment continues.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Hospitals, Teaching ; Humans ; Infant ; Male ; Middle Aged ; Nigeria ; Prospective Studies ; Skin Diseases/diagnosis ; Skin Diseases/epidemiology ; Young Adult
Language	English
Publishing date	2015-04
Publishing country	England
Document type	Journal Article
ZDB-ID	412254-9
ISSN	1365-4632 ; 0011-9059 ; 1461-1244
ISSN (online)	1365-4632
ISSN	0011-9059 ; 1461-1244
DOI	10.1111/ijd.12693
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Article: Kidney disease in elderly South Africans.

Okpechi, Ikechi G / Ayodele, Olugbenga E / Rayner, Brian L / Swanepoel, Charles R

Clinical nephrology

2013 Volume 79, Issue 4, Page(s) 269–276

Abstract: Background: Life expectancy is low in many African countries due to several factors including the ongoing HIV epidemic. However, the global increase in life expectancy has translated to more elderly patients living with chronic kidney disease (CKD). The ...

Abstract	Background: Life expectancy is low in many African countries due to several factors including the ongoing HIV epidemic. However, the global increase in life expectancy has translated to more elderly patients living with chronic kidney disease (CKD). The patterns of kidney disease in the elderly have never been described from sub-Saharan Africa. Methods: This study was a retrospective study of 111 elderly patients (age ≥ 60 years) who had a renal biopsy performed at the Groote Schuur Hospital in Cape Town between 1st January 2000 and 31st December 2009. Results: The mean age of patients at time of biopsy was 66.3 ± 5.7 years (males: 66.4 ± 5.6; females: 66.3 ± 5.9 years). Primary glomerular diseases were seen in 38.7%, secondary glomerular diseases in 36.0%, tubulointerstitial diseases in 17.1% and diseases classified as miscellaneous in 8.1% of all patients. Nephrotic syndrome was the most common indication for the performance of a renal biopsy (48.6%). Membranous lomerulonephritis (MGN) was the most common type of disease observed (14.4%) and was significantly more frequent in males than in females (p = 0.029). Other common histological diagnoses included diabetes nephropathy (12.6%), chronic glomerulonephritis (5.4%), and lupus nephritis (4.5%). HIV associated nephropathy (HIVAN) was only seen in 1 patient (0.9%). Conclusion: The patterns of renal disease currently seen in elderly South Africans closely resembles that reported from other countries but is at complete variance with the pattern reported in the general population of South Africa in which HIV plays a significant role.
MeSH term(s)	Age Distribution ; Age Factors ; Aged ; Aged, 80 and over ; Analysis of Variance ; Biopsy ; Chi-Square Distribution ; Female ; Humans ; Kidney/pathology ; Kidney Diseases/diagnosis ; Kidney Diseases/epidemiology ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Sex Distribution ; Sex Factors ; South Africa/epidemiology ; Time Factors
Language	English
Publishing date	2013-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	185101-9
ISSN	0301-0430
ISSN	0301-0430
DOI	10.5414/CN107746
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Article ; Online: Denture impaction in the oesophagus experience of a young ENT practice in Nigeria.

Adedeji, Taiwo Olugbemiga / Olaosun, Adedayo Olugbenga / Sogebi, Olusola Ayodele / Tobih, James E

The Pan African medical journal

2014 Volume 18, Page(s) 330

Abstract: Introduction: The effect of dental loss and associated desire to restore its function and aesthesis has led to an increase in the number of people wearing dentures. This study therefore reviews the cases of impacted acrylic dentures in the oesophagus.!## ...

Abstract	Introduction: The effect of dental loss and associated desire to restore its function and aesthesis has led to an increase in the number of people wearing dentures. This study therefore reviews the cases of impacted acrylic dentures in the oesophagus. Methods: A retrospective review of patients that were managed for oesophageal denture impaction at Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Osun State, Nigeria, over an eight year period from 2005 to 2012. Results: A total of 14 patients (M:F 2.5:1). The age ranged from 32-75 years. Majority 64.3%) were 51 years and above. Over 70% presented early. Major presenting symptoms were throat pain (100%), odynophageal (92.9%) and dysphageal (78.6%). The radiographic findings were air entrapment (64.3%) and increase in prevertebral soft tissue shadow (78.6%). Majority (87.5%) were impacted at the upper (cervical) oesophagus. Over 78% had successful extraction with rigid oesophagoscopy. Two (14.3%) had spontaneous expulsion of the denture and 1 (7.1%) discharged himself against medical advice. Complications were mucosa tear (28.6%), laryngeal spasm/ airway obstruction (14.3%), mucosa oedema/ erythema (57.1%), neck abscess (7.1%). Conclusion: Impaction of esophageal dentures is relatively common in our locality; most patients present early for medical attention and associated with successful rigid oesophagoscopies and denture extraction under GA, and generally good outcome. Education of the wearers of dentures was emphasized as a way of preventing dentures impaction.
MeSH term(s)	Adult ; Aged ; Deglutition Disorders/etiology ; Dentures/adverse effects ; Esophagoscopy/methods ; Esophagus/pathology ; Female ; Foreign Bodies/complications ; Hospitals, Teaching ; Humans ; Male ; Middle Aged ; Nigeria ; Retrospective Studies
Language	English
Publishing date	2014
Publishing country	Uganda
Document type	Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2014.18.330.2871
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Article ; Online: Sodium butyrate arrests pancreato-hepatic synchronous uric acid and lipid dysmetabolism in high fat diet fed Wistar rats.

Adeyanju, Oluwaseun A / Badejogbin, Olabimpe C / Areola, Damilare E / Olaniyi, Kehinde S / Dibia, Chinaza / Soetan, Olaniyi A / Oniyide, Adesola A / Michael, Olugbenga S / Olatunji, Lawrence A / Soladoye, Ayodele O

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2020 Volume 133, Page(s) 110994

Abstract: High fat diet (HFD) is a risk factor for metabolic syndrome which is characterized by overt glucose dysmetabolism and tissue derangement. The liver and pancreas are important metabolic tissues with anatomical proximity sharing splanchnic and mesenteric ... ...

Abstract	High fat diet (HFD) is a risk factor for metabolic syndrome which is characterized by overt glucose dysmetabolism and tissue derangement. The liver and pancreas are important metabolic tissues with anatomical proximity sharing splanchnic and mesenteric circulation but it is unclear whether, there is an associated metabolic status between the two organs in health and disease. Uric acid (UA) hypersecretion and ectopic lipid accumulation are characteristic pathophysiology of an array of non-communicable diseases. Sodium butyrate (BUT) is reputed for therapeutic roles in metabolic derangement. Therefore, the present study investigated synchrony in hepatic and pancreatic UA and lipid metabolic status in HFD-induced glucose dysregulation and probed the beneficial effects of BUT. Twenty-four female Wistar rats were treated with normal rat chow and distilled water (po) or sodium butyrate (200 mg/kg; po) or high fat diet and distilled water (po) or high fat diet and sodium butyrate. Results showed that HFD increased plasma, pancreatic and hepatic triglyceride, triglyceride-glucose index, malondialdehyde, uric acid (UA), lactate dehydrogenase but reduced glucose-6-phosphate dehydrogenase. Histological analysis revealed hepatic and pancreatic architectural derangement and cellular degeneration in HFD-fed animals. However, BUT reversed the HFD-induced systemic, pancreatic and hepatic synchronous dysmetabolism with evidence of improved histology. HFD-induced lipid and UA alterations were synchronous in the pancreas and liver. BUT elicits beneficial effects on systemic and tissue HFD-induced deleterious metabolic changes which were synchronized in pancreas and liver of rats.
MeSH term(s)	Animals ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Butyric Acid/pharmacology ; Diet, High-Fat ; Disease Models, Animal ; Dyslipidemias/blood ; Dyslipidemias/drug therapy ; Dyslipidemias/etiology ; Dyslipidemias/pathology ; Female ; Glucose Metabolism Disorders/blood ; Glucose Metabolism Disorders/drug therapy ; Glucose Metabolism Disorders/etiology ; Hyperuricemia/blood ; Hyperuricemia/drug therapy ; Hyperuricemia/etiology ; Hyperuricemia/pathology ; Hypoglycemic Agents/pharmacology ; Hypolipidemic Agents/pharmacology ; Lipids/blood ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Metabolic Syndrome/blood ; Metabolic Syndrome/drug therapy ; Metabolic Syndrome/etiology ; Metabolic Syndrome/pathology ; Pancreas/drug effects ; Pancreas/metabolism ; Pancreas/pathology ; Rats, Wistar ; Uric Acid/blood ; Rats
Chemical Substances	Blood Glucose ; Hypoglycemic Agents ; Hypolipidemic Agents ; Lipids ; Butyric Acid (107-92-6) ; Uric Acid (268B43MJ25)
Language	English
Publishing date	2020-11-13
Publishing country	France
Document type	Journal Article
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2020.110994
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Article ; Online: Interest in neurology during medical clerkship in three Nigerian medical schools.

Sanya, Emmanuel O / Ayodele, Olugbenga E / Olanrewaju, Timothy O

BMC medical education

2010 Volume 10, Page(s) 36

Abstract: Background: This study sought to ascertain perception of Nigerian medical students of neurology in comparison with 7 other major medical specialties. To also determine whether neurology was the specialty students consider most difficult and the reasons ... ...

Abstract	Background: This study sought to ascertain perception of Nigerian medical students of neurology in comparison with 7 other major medical specialties. To also determine whether neurology was the specialty students consider most difficult and the reasons for this and to appraise their opinion on how neurosciences and neurology were taught in their different universities. Methods: Self-administered questionnaires were used to obtain information from randomly selected clinical students from 3 medical colleges in Nigeria (University of Ibadan, Ibadan; University of Ilorin, Ilorin; Ladoke Akintola University of Technology, Osogbo). Results: Of 320 questionnaires sent out, 302 were returned given 94% response rate. Students felt they knew neurology least of all the 8 medical specialties, and were not confident of making neurological diagnoses. About 82% of the students indicated they learnt neurology best from bedside teaching, followed by use of medical textbooks. Close to 15% found online resources very useful for learning neurology and 6% indicated that group discussion was quite useful in the acquisition of knowledge on neurology. Histology and biochemistry were the preclinical subjects participants opined were least useful in learning neurology. The most frequent reasons students felt neurology was difficult were problems with understanding neuroanatomy (49%), insufficient exposure to neurological cases (41%), too many complex diagnoses (32%) and inadequate neurology teachers (32%). Conclusions: Nigerian medical students perceived neurology as the most difficult medical specialty and are not interested in specializing in it. Neurology education could be improved upon by provision of more bedside tutorials and increased availability of online resources to enhance learning. There is need to emphasize increased frequency of small group discussions amongst students so that they will be used to teamwork after graduation.
MeSH term(s)	Clinical Clerkship ; Female ; Humans ; Male ; Neurology/education ; Nigeria ; Schools, Medical ; Students, Medical/psychology ; Surveys and Questionnaires
Language	English
Publishing date	2010-05-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2044473-4
ISSN	1472-6920 ; 1472-6920
ISSN (online)	1472-6920
ISSN	1472-6920
DOI	10.1186/1472-6920-10-36
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In stock of ZB MED Cologne/Königswinter

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Full text online

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In stock of ZB MED Cologne/Königswinter

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More links

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Order via subito