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  1. Article: Deep learning architectures for diagnosing the severity of apple frog-eye leaf spot disease in complex backgrounds.

    Liu, Bo / Fan, Hongyu / Zhang, Yuting / Cai, Jinjin / Cheng, Hong

    Frontiers in plant science

    2024  Volume 14, Page(s) 1289497

    Abstract: Introduction: In precision agriculture, accurately diagnosing apple frog-eye leaf spot disease is critical for effective disease management. Traditional methods, predominantly relying on labor-intensive and subjective visual evaluations, are often ... ...

    Abstract Introduction: In precision agriculture, accurately diagnosing apple frog-eye leaf spot disease is critical for effective disease management. Traditional methods, predominantly relying on labor-intensive and subjective visual evaluations, are often inefficient and unreliable.
    Methods: To tackle these challenges in complex orchard environments, we develop a specialized deep learning architecture. This architecture consists of a two-stage multi-network model. The first stage features an enhanced Pyramid Scene Parsing Network (L-DPNet) with deformable convolutions for improved apple leaf segmentation. The second stage utilizes an improved U-Net (D-UNet), optimized with bilinear upsampling and batch normalization, for precise disease spot segmentation.
    Results: Our model sets new benchmarks in performance, achieving a mean Intersection over Union (mIoU) of 91.27% for segmentation of both apple leaves and disease spots, and a mean Pixel Accuracy (mPA) of 94.32%. It also excels in classifying disease severity across five levels, achieving an overall precision of 94.81%.
    Discussion: This approach represents a significant advancement in automated disease quantification, enhancing disease management in precision agriculture through data-driven decision-making.
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1289497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Study of Optimal Adsorption Conditions of Phosphate on Fe-Modified Biochar by Response Surface Methodology.

    Qian, Jing / Zhou, Xiaoyu / Cai, Qingsong / Zhao, Jinjin / Huang, Xianhuai

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 5

    Abstract: A batch of Fe-modified biochars MS (for soybean straw), MR (for rape straw), and MP (for peanut shell) were prepared by impregnating biochars pyrolyzed from three different raw biomass materials, i.e., peanut shell, soybean straw, and rape straw, with ... ...

    Abstract A batch of Fe-modified biochars MS (for soybean straw), MR (for rape straw), and MP (for peanut shell) were prepared by impregnating biochars pyrolyzed from three different raw biomass materials, i.e., peanut shell, soybean straw, and rape straw, with FeCl
    MeSH term(s) Phosphates ; Adsorption ; Charcoal/chemistry ; Phosphorus ; Water Pollutants, Chemical/chemistry
    Chemical Substances biochar ; Phosphates ; Charcoal (16291-96-6) ; Phosphorus (27YLU75U4W) ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-03-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28052323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Clinical and genetic analysis

    Zhang, Jinjin / Cai, Bo / Ma, Limei / Qin, Yixuan / Li, Shuai / Sun, Caihong / Liang, Jing / Han, Yu / Zhuang, Wenjuan

    Frontiers in genetics

    2023  Volume 14, Page(s) 1145426

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2023-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1145426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Study of Optimal Adsorption Conditions of Phosphate on Fe-Modified Biochar by Response Surface Methodology

    Jing Qian / Xiaoyu Zhou / Qingsong Cai / Jinjin Zhao / Xianhuai Huang

    Molecules, Vol 28, Iss 2323, p

    2023  Volume 2323

    Abstract: A batch of Fe-modified biochars MS (for soybean straw), MR (for rape straw), and MP (for peanut shell) were prepared by impregnating biochars pyrolyzed from three different raw biomass materials, i.e., peanut shell, soybean straw, and rape straw, with ... ...

    Abstract A batch of Fe-modified biochars MS (for soybean straw), MR (for rape straw), and MP (for peanut shell) were prepared by impregnating biochars pyrolyzed from three different raw biomass materials, i.e., peanut shell, soybean straw, and rape straw, with FeCl 3 solution in different Fe/C impregnation ratios (0, 0.112, 0.224, 0.448, 0.560, 0.672, and 0.896) in this research. Their characteristics (pH, porosities, surface morphologies, crystal structures, and interfacial chemical behaviors) and phosphate adsorption capacities and mechanisms were evaluated. The optimization of their phosphate removal efficiency (Y%) was analyzed using the response surface method. Our results indicated that MR, MP, and MS showed their best phosphate adsorption capacity at Fe/C ratios of 0.672, 0.672, and 0.560, respectively. Rapid phosphate removal was observed within the first few minutes and the equilibrium was attained by 12 h in all treatment. The optimal conditions for phosphorus removal were pH = 7.0, initial phosphate concentration = 132.64 mg L −1 , and ambient temperature = 25 °C, where the Y% values were 97.76, 90.23, and 86.23% of MS, MP, and MR, respectively. Among the three biochars, the maximum phosphate removal efficiency determined was 97.80%. The phosphate adsorption process of three modified biochars followed a pseudo-second-order adsorption kinetic model, indicating monolayer adsorption based on electrostatic adsorption or ion exchange. Thus, this study clarified the mechanism of phosphate adsorption by three Fe-modified biochar composites, which present as low-cost soil conditioners for rapid and sustainable phosphate removal.
    Keywords phosphate removal ; Fe-modified biochar ; response surface method ; optimization ; adsorption–desorption ; Organic chemistry ; QD241-441
    Subject code 620
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The challenge of managing ischemic stroke in brucellosis: a case report.

    Chen, Linfa / Lin, Xiaolong / Cai, Xiuqu / Zeng, Shiting / Yuan, Yanquan / Huang, Zhiyong / Yan, Jinjin / Li, You

    Frontiers in immunology

    2024  Volume 15, Page(s) 1347216

    Abstract: A 64-year-old woman was admitted to the hospital for sudden weakness in one of her left limbs. The patient was diagnosed with acute ischemic stroke (IS) of undetermined cause and received intravenous thrombolysis. Following thrombolysis, the patient's ... ...

    Abstract A 64-year-old woman was admitted to the hospital for sudden weakness in one of her left limbs. The patient was diagnosed with acute ischemic stroke (IS) of undetermined cause and received intravenous thrombolysis. Following thrombolysis, the patient's left limb weakness improved, but she subsequently developed recurrent high fever and delirium. Further diagnostic tests revealed that she had been infected with
    MeSH term(s) Humans ; Female ; Middle Aged ; Ischemic Stroke ; Brucellosis ; Brucella melitensis ; Stroke/complications ; Anti-Infective Agents
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2024-03-12
    Publishing country Switzerland
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1347216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effect of preheating-induced denaturation of proteins and oleosomes on the structure of protein and soymilk properties.

    Huangfu, Junjing / Huang, Lihua / Gu, Yue / Yang, Shuo / Wu, Jinjin / Liu, Tongxun / Cai, Yongjian / Zhao, Mouming / Zhao, Qiangzhong

    International journal of biological macromolecules

    2024  Volume 268, Issue Pt 2, Page(s) 131999

    Abstract: In this paper, effects of preheating-induced denaturation of proteins and oleosomes on protein structure and soymilk quality were studied. The protein in soybeans baked at 55 °C (B-55) and 85 °C (B-85) showed an increase of β-sheet content by 3.2 % and a ...

    Abstract In this paper, effects of preheating-induced denaturation of proteins and oleosomes on protein structure and soymilk quality were studied. The protein in soybeans baked at 55 °C (B-55) and 85 °C (B-85) showed an increase of β-sheet content by 3.2 % and a decrease of α-helix content by 3.3 %, indicating that proteins were gradually unfolded while oleosomes remained intact. The protein resisted thermal denaturation during secondary heating, and soymilks were stable as reflected by a small d
    Language English
    Publishing date 2024-04-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.131999
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Systematic investigation of the material basis, multiple mechanisms and quality control of Simiao Yong'an decoction combined with antibiotic in the treatment of sepsis.

    Cai, Zhihui / He, Jinjin / Jiang, Jun / Zhao, Zihan / Shu, Ye

    Phytomedicine : international journal of phytotherapy and phytopharmacology

    2023  Volume 116, Page(s) 154910

    Abstract: Background: Sepsis is one of the major threats to human health with high mortality. Simiao Yong'an decoction (SMYAD) has the efficacy of anti-inflammation, improving coagulation and microcirculation, which is applicable for the clinical assistance ... ...

    Abstract Background: Sepsis is one of the major threats to human health with high mortality. Simiao Yong'an decoction (SMYAD) has the efficacy of anti-inflammation, improving coagulation and microcirculation, which is applicable for the clinical assistance treatment of sepsis. Yet, its material basis and relevant mechanisms are still vague.
    Purpose: Explore the quality markers (Q-markers), biomarkers and potential mechanisms of SMYAD combined with imipenem/cilastatin sodium for anti-sepsis.
    Methods: Linear-Trap-LC/MS
    Results: The 25 serum migrant ingredients derived from 113 chemical compounds of SMYAD were identified for the first time, and 6 components were determined as the Q-markers of SMYAD. The enrichment analysis indicated that the potential mechanism was mainly associated with the IL-17 signaling pathway, complement-coagulation cascades signaling pathway and VEGF signaling pathway. Then, SMYAD united antibiotic declined the mortality of septic rats, restored cytokine levels, ameliorated histopathological lesions and decreased the mRNA and protein expression of target proteins in a dose-dependent way. Furthermore, 8 differential metabolites were regarded as latent biomarkers related to the antiseptic effect of SMYAD united antibiotic, which were mainly involved in the Citrate cycle (TCA cycle) metabolic pathway.
    Conclusions: Different skeletons of compounds, including iridoids, phenylpropanoids, organic acids, triterpenes and others, were the main compositions of SMYAD. Among them, 6 components were determined as the Q-markers, which provided a basis for the construction of quality standards for this ancient classic formula. The combination therapy of SMYAD and antibiotic obviously ameliorated inflammatory reaction, coagulation dysfunction and microcirculation abnormalities for sepsis by inhibiting IL-17 signaling pathway, complement-coagulation cascades signaling pathway and VEGF signaling pathway.
    MeSH term(s) Humans ; Rats ; Animals ; Drugs, Chinese Herbal/pharmacology ; Interleukin-17 ; Anti-Bacterial Agents/pharmacology ; Vascular Endothelial Growth Factor A ; Sepsis/drug therapy ; Quality Control
    Chemical Substances Drugs, Chinese Herbal ; Interleukin-17 ; Anti-Bacterial Agents ; Vascular Endothelial Growth Factor A
    Language English
    Publishing date 2023-05-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1205240-1
    ISSN 1618-095X ; 0944-7113
    ISSN (online) 1618-095X
    ISSN 0944-7113
    DOI 10.1016/j.phymed.2023.154910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Subchronic Toxicity of Microcystin-LR on Young Frogs (

    Li, Jinjin / Sun, Hongzhao / Wang, Chun / Li, Shangchun / Cai, Yunfei

    Frontiers in microbiology

    2022  Volume 13, Page(s) 895383

    Abstract: Although toxic effects of microcystins (MCs) in mammals and fish have been extensively studied, the effects of MCs on the immune system and gut microbiota of amphibians have not received sufficient attention. As MCs cause general damage to the vertebrate ...

    Abstract Although toxic effects of microcystins (MCs) in mammals and fish have been extensively studied, the effects of MCs on the immune system and gut microbiota of amphibians have not received sufficient attention. As MCs cause general damage to the vertebrate liver and immune system and trigger an inflammatory response, and the gut microbiota is closely related to host metabolism and immunity, we speculated that MCs can cause changes in the immune system and gut microbiota of amphibians. To verify this, we examined the intestinal and liver injury of
    Language English
    Publishing date 2022-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.895383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Machine-learning-assisted rational design of 2D doped tellurene for fin field-effect transistor devices.

    Chen, An / Ye, Simin / Wang, Zhilong / Han, Yanqiang / Cai, Junfei / Li, Jinjin

    Patterns (New York, N.Y.)

    2023  Volume 4, Issue 4, Page(s) 100722

    Abstract: Fin field-effect transistors (FinFETs) have been widely used in electronic devices on account of their excellent performance, but this new type of device is facing many challenges because of size constraints. Two-dimensional (2D) materials with a layer ... ...

    Abstract Fin field-effect transistors (FinFETs) have been widely used in electronic devices on account of their excellent performance, but this new type of device is facing many challenges because of size constraints. Two-dimensional (2D) materials with a layer structure can meet the required thickness of FinFETs and provide ideal carrier transport performance. In this work, we used 2D tellurene as the parent material and modified it with doping techniques to improve electronic device performance. High-performance FinFET devices were prepared with 23 systems screened from 385 doping systems by a combination of first-principle calculations and a machine-learning (ML) model. Moreover, theoretical calculations demonstrated that 1S1@Te and 2S2@Te have high carrier mobility and stability with an electron mobility and a hole mobility of 6.211 × 10
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3899
    ISSN (online) 2666-3899
    DOI 10.1016/j.patter.2023.100722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Single atom modified two-dimensional bismuthenes for toxic gas detection.

    Chen, An / Han, Yanqiang / Wang, Zhilong / Cai, Junfei / Ye, Simin / Li, Jinjin

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 13, Page(s) 9249–9255

    Abstract: Accurate detection of toxic gases at low concentrations is often difficult because they are colorless, odorless, flammable and denser than air. Therefore, it is urgent to develop highly stable and sensitive toxic gas detectors. However, most gas sensors ... ...

    Abstract Accurate detection of toxic gases at low concentrations is often difficult because they are colorless, odorless, flammable and denser than air. Therefore, it is urgent to develop highly stable and sensitive toxic gas detectors. However, most gas sensors operate at high temperatures, making the detection of toxic gases more challenging. Two-dimensional materials with high specific surface area and abundant modulation methods of properties provide new inspirations for the development of new toxic gas sensing materials. Here, bismuthene, a single element two-dimensional material with high carrier mobility and excellent stability, was used as a substrate material to investigate the effects of anchoring and doping on its gas detection performance by density functional theory (DFT) calculations. It is revealed that the surface structure altered by single metal atoms (Ba, Be, Ca, K, Li, Mg, Na, and Sr) can promote the improvement of gas detection sensitivity. Buckled honeycomb bismuthene (bBi) with the Be atom anchored (A-Be-Bi) show superior sensitivity to H
    Language English
    Publishing date 2023-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp00103b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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