LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 693

Search options

  1. Book ; Thesis: Medische microbiologie en infectieziekten

    Verweij, Paul Eduard

    duellum aut dualitas

    2005  

    Author's details door P. E. Verweij
    Language Dutch
    Size 16 S. : Ill.
    Publishing country Netherlands
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Nijmegen, Radboud Univ., Rede, 2005
    HBZ-ID HT014569326
    ISBN 90-9019208-5 ; 978-90-9019208-6
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 E 2190 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Antifungal Resistance in Pulmonary Aspergillosis.

    Verweij, Paul E / Song, Yinggai / Buil, Jochem B / Zhang, Jianhua / Melchers, Willem J G

    Seminars in respiratory and critical care medicine

    2024  Volume 45, Issue 1, Page(s) 32–40

    Abstract: Aspergilli may cause various pulmonary diseases in humans, including allergic bronchopulmonary aspergillosis (ABPA), chronic pulmonary aspergillosis (CPA), and acute invasive pulmonary aspergillosis (IPA). In addition, chronic colonization may occur in ... ...

    Abstract Aspergilli may cause various pulmonary diseases in humans, including allergic bronchopulmonary aspergillosis (ABPA), chronic pulmonary aspergillosis (CPA), and acute invasive pulmonary aspergillosis (IPA). In addition, chronic colonization may occur in cystic fibrosis (CF).
    MeSH term(s) Humans ; Antifungal Agents/pharmacology ; Antifungal Agents/therapeutic use ; Pulmonary Aspergillosis/drug therapy ; Pulmonary Aspergillosis/diagnosis ; Pulmonary Aspergillosis/microbiology ; Aspergillus fumigatus/genetics ; Aspergillus ; Aspergillosis, Allergic Bronchopulmonary/drug therapy ; Cystic Fibrosis/drug therapy ; Chronic Disease ; Persistent Infection
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1183617-9
    ISSN 1098-9048 ; 1069-3424
    ISSN (online) 1098-9048
    ISSN 1069-3424
    DOI 10.1055/s-0043-1776997
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1555: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Fungal infections should be part of the core outcome set for COVID-19.

    Verweij, Paul E / Alanio, Alexandre

    The Lancet. Infectious diseases

    2020  Volume 21, Issue 6, Page(s) e145

    MeSH term(s) COVID-19/complications ; COVID-19/diagnosis ; Humans ; Influenza, Human ; Intensive Care Units ; Mycoses/complications ; Mycoses/diagnosis ; Mycoses/drug therapy ; Mycoses/microbiology ; Outcome Assessment, Health Care ; Pulmonary Aspergillosis ; Risk Factors ; SARS-CoV-2 ; COVID-19 Drug Treatment
    Language English
    Publishing date 2020-12-07
    Publishing country United States
    Document type Letter
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30591-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5743: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Aspergillus fumigatus and pan-azole resistance: who should be concerned?

    Wiederhold, Nathan P / Verweij, Paul E

    Current opinion in infectious diseases

    2020  Volume 33, Issue 4, Page(s) 290–297

    Abstract: Purpose of review: Although clinical outcomes in the treatment of aspergillosis have markedly improved with the availability of newer triazoles, the development of resistance to these antifungals, especially in Aspergillus fumigatus, is a growing ... ...

    Abstract Purpose of review: Although clinical outcomes in the treatment of aspergillosis have markedly improved with the availability of newer triazoles, the development of resistance to these antifungals, especially in Aspergillus fumigatus, is a growing concern. The purpose of this review is to provide an update on azole resistance mechanisms and their epidemiology in A. fumigatus, the clinical implications of azole resistance, and to discuss future treatment options against azole-resistant aspergillosis.
    Recent findings: Resistance may develop through either patient or environmental azole exposure. Environmental exposure is the most prevalent means of resistance development, and these isolates can cause disease in various at-risk groups, which now include those with influenza, and potentially COVID-19. Although current treatment options are limited, newer therapies are in clinical development. These include agents with novel mechanisms of action which have in vitro and in vivo activity against azole-resistant A. fumigatus.
    Summary: Azole-resistant A. fumigatus is an emerging threat that hampers our ability to successfully treat patients with aspergillosis. Certain geographic regions and patient populations appear to be at increased risk for this pathogen. As new patient groups are increasingly recognized to be at increased risk for invasive aspergillosis, studies to define the epidemiology and management of azole-resistant A. fumigatus are critically needed. While treatment options are currently limited, new agents under clinical development may offer hope.
    MeSH term(s) Antifungal Agents/pharmacology ; Antifungal Agents/therapeutic use ; Aspergillosis/drug therapy ; Aspergillosis/immunology ; Aspergillosis/microbiology ; Aspergillus fumigatus/drug effects ; Aspergillus fumigatus/immunology ; Betacoronavirus/immunology ; COVID-19 ; Coronavirus Infections/immunology ; Drug Resistance, Multiple, Fungal/immunology ; Environmental Exposure ; Humans ; Immunocompromised Host/immunology ; Microbial Sensitivity Tests ; Pandemics ; Pneumonia, Viral/immunology ; SARS-CoV-2 ; Triazoles/pharmacology ; Triazoles/therapeutic use
    Chemical Substances Antifungal Agents ; Triazoles
    Keywords covid19
    Language English
    Publishing date 2020-07-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645085-4
    ISSN 1473-6527 ; 1535-3877 ; 0951-7375 ; 1355-834X
    ISSN (online) 1473-6527 ; 1535-3877
    ISSN 0951-7375 ; 1355-834X
    DOI 10.1097/QCO.0000000000000662
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2462: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints.

    Jansen, Anouk M E / Ter Heine, Rob / Verweij, Paul E / Brüggemann, Roger J M

    Clinical pharmacokinetics

    2023  Volume 62, Issue 12, Page(s) 1695–1699

    Abstract: Isavuconazole exposure-response relationships have been studied with a focus on total rather than unbound exposure, assuming a constant unbound fraction of 1%. We observed a median (range) unbound fraction of 1.59% (0.42-5.30%) in patients. This highly ... ...

    Abstract Isavuconazole exposure-response relationships have been studied with a focus on total rather than unbound exposure, assuming a constant unbound fraction of 1%. We observed a median (range) unbound fraction of 1.59% (0.42-5.30%) in patients. This highly variable protein binding asks for re-evaluation of current pharmacokinetic and pharmacodynamic targets for isavuconazole.
    MeSH term(s) Humans ; Protein Binding ; Nitriles/pharmacokinetics ; Pyridines/therapeutic use ; Pyridines/pharmacokinetics ; Triazoles/pharmacokinetics
    Chemical Substances isavuconazole (60UTO373KE) ; Nitriles ; Pyridines ; Triazoles
    Language English
    Publishing date 2023-10-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 197627-8
    ISSN 1179-1926 ; 0312-5963
    ISSN (online) 1179-1926
    ISSN 0312-5963
    DOI 10.1007/s40262-023-01311-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1246: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Fungal Fog in Viral Storms: Necessity for Rigor in Aspergillosis Diagnosis and Research.

    Feys, Simon / Hoenigl, Martin / Gangneux, Jean-Pierre / Verweij, Paul E / Wauters, Joost

    American journal of respiratory and critical care medicine

    2023  Volume 209, Issue 6, Page(s) 631–633

    MeSH term(s) Humans ; Aspergillosis/diagnosis ; Aspergillosis/drug therapy ; Lung Diseases, Fungal/diagnosis
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202310-1815VP
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Managing secondary fungal infections in severe COVID-19: how to move forward?

    Verweij, Paul E / van de Veerdonk, Frank L

    The Lancet. Respiratory medicine

    2021  Volume 10, Issue 2, Page(s) 127–128

    MeSH term(s) COVID-19 ; Coinfection ; Humans ; Mycoses ; SARS-CoV-2
    Language English
    Publishing date 2021-11-26
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00500-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 7041: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Aspergillus

    Hiel, Stephan J P / Hendriks, Amber C A / Eijkenboom, Jos J A / Bosch, Thijs / Coolen, Jordy P M / Melchers, Willem J G / Anröchte, Paul / Camps, Simone M T / Verweij, Paul E / Zhang, Jianhua / Dommelen, Laura van

    Journal of fungi (Basel, Switzerland)

    2024  Volume 10, Issue 1

    Abstract: Whole genome sequencing (WGS) is widely used for outbreak analysis of bacteriology and virology but is scarcely used in mycology. Here, we used WGS for ... ...

    Abstract Whole genome sequencing (WGS) is widely used for outbreak analysis of bacteriology and virology but is scarcely used in mycology. Here, we used WGS for genotyping
    Language English
    Publishing date 2024-01-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof10010051
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Differential Functions of Individual Transcription Factor Binding Sites in the Tandem Repeats Found in Clinically Relevant

    Paul, Sanjoy / Verweij, Paul E / Melchers, Willem J G / Moye-Rowley, W Scott

    mBio

    2022  Volume 13, Issue 3, Page(s) e0070222

    Abstract: Aspergillus fumigatus is the major filamentous fungal pathogen in humans. The gold standard treatment of A. fumigatus is based on azole drug use, but the appearance of azole-resistant isolates is increasing at an alarming rate. ... ...

    Abstract Aspergillus fumigatus is the major filamentous fungal pathogen in humans. The gold standard treatment of A. fumigatus is based on azole drug use, but the appearance of azole-resistant isolates is increasing at an alarming rate. The
    MeSH term(s) Antifungal Agents/metabolism ; Antifungal Agents/pharmacology ; Aspergillus fumigatus/metabolism ; Azoles/pharmacology ; Binding Sites ; Cytochrome P-450 Enzyme System/genetics ; Cytochrome P-450 Enzyme System/metabolism ; Drug Resistance, Fungal/genetics ; Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Microbial Sensitivity Tests ; Promoter Regions, Genetic ; Tandem Repeat Sequences ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Voriconazole/metabolism
    Chemical Substances Antifungal Agents ; Azoles ; Fungal Proteins ; Transcription Factors ; Cytochrome P-450 Enzyme System (9035-51-2) ; cytochrome P-450 CYP51A, Aspergillus (EC 1.14.14.-) ; Voriconazole (JFU09I87TR)
    Language English
    Publishing date 2022-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mbio.00702-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Selective Flamingo Medium for the Isolation of

    Zhang, Jianhua / Debets, Alfons J M / Verweij, Paul E / Schoustra, Sijmen E

    Microorganisms

    2021  Volume 9, Issue 6

    Abstract: For various studies in the clinic as well as the environment, it is essential to be able to selectively ... ...

    Abstract For various studies in the clinic as well as the environment, it is essential to be able to selectively isolate
    Language English
    Publishing date 2021-05-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9061155
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top