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  1. Article ; Online: Pre-Heart Failure Risk Assessment: Don't Get Lost in an Echo Chamber!

    Khan, Sadiya S / Shah, Sanjiv J

    Journal of cardiac failure

    2023  Volume 29, Issue 11, Page(s) 1490–1493

    MeSH term(s) Humans ; Heart Failure/diagnosis ; Risk Adjustment
    Language English
    Publishing date 2023-07-31
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.07.007
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    Zs.A 4340: Show issues Location:
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  2. Article ; Online: HFpEF in Japan: When an Epidemiological Transition Becomes an Epidemiological Opportunity.

    Mitter, Sumeet S / Shah, Sanjiv J

    Journal of cardiac failure

    2023  Volume 29, Issue 8, Page(s) 1228–1230

    MeSH term(s) Humans ; Heart Failure/epidemiology ; Heart Failure/therapy ; Stroke Volume ; Japan/epidemiology
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.02.005
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  3. Article ; Online: Hereditary Transthyretin Amyloid Cardiomyopathy.

    Youmans, Quentin R / Shah, Sanjiv J / Khan, Sadiya S

    JAMA cardiology

    2022  Volume 7, Issue 2, Page(s) 236

    MeSH term(s) Amyloid Neuropathies, Familial/diagnosis ; Amyloid Neuropathies, Familial/metabolism ; Amyloid Neuropathies, Familial/physiopathology ; Amyloid Neuropathies, Familial/therapy ; Cardiomyopathies/diagnosis ; Cardiomyopathies/metabolism ; Cardiomyopathies/physiopathology ; Cardiomyopathies/therapy ; Humans
    Language English
    Publishing date 2022-01-05
    Publishing country United States
    Document type Journal Article ; Patient Education Handout
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2021.5006
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  4. Article ; Online: Case Reviews in Head and Neck Vascular Lesion Management.

    Kumar, Balasubramanya / Chandra, Srinivasa R / Nair, Sanjiv / Shah, Anjan Kumar

    Oral and maxillofacial surgery clinics of North America

    2023  Volume 36, Issue 1, Page(s) 81–92

    Abstract: ... upon the size of the lesion(s), morphology, location, presence or possibility of complications, the potential ...

    Abstract The treatment of hemangiomas and vascular malformations should be individualized, based upon the size of the lesion(s), morphology, location, presence or possibility of complications, the potential for scarring or disfigurement, the age of the patient, and the rate of growth or involution at the time of evaluation. The major challenge is the location in a head and neck can lead to unsightly scars if approached improperly, or with inadequate approaches can lead to intraoperative and postoperative morbidity with neurovascular damage and inadequate lesion excision. Facial, trigeminal, and other cranial nerve branches are of key importance in the functional outcome while accessing and approaching head and neck vascular lesions.
    MeSH term(s) Humans ; Neck/surgery ; Face/surgery
    Language English
    Publishing date 2023-09-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1316546-x
    ISSN 1558-1365 ; 1042-3699
    ISSN (online) 1558-1365
    ISSN 1042-3699
    DOI 10.1016/j.coms.2023.09.003
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  5. Article ; Online: Could a Low-Dose Diuretic Polypill Improve Outcomes in Heart Failure With Preserved Ejection Fraction?

    Khan, Sadiya S / Huffman, Mark D / Shah, Sanjiv J

    Circulation. Heart failure

    2021  Volume 14, Issue 3, Page(s) e008090

    MeSH term(s) Drug Combinations ; Heart Failure/drug therapy ; Heart Failure/physiopathology ; Hospitalization ; Humans ; Mineralocorticoid Receptor Antagonists/administration & dosage ; Sodium Chloride Symporter Inhibitors/administration & dosage ; Sodium Potassium Chloride Symporter Inhibitors/administration & dosage ; Sodium-Glucose Transporter 2 Inhibitors/administration & dosage ; Stroke Volume
    Chemical Substances Drug Combinations ; Mineralocorticoid Receptor Antagonists ; Sodium Chloride Symporter Inhibitors ; Sodium Potassium Chloride Symporter Inhibitors ; Sodium-Glucose Transporter 2 Inhibitors
    Language English
    Publishing date 2021-03-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429459-7
    ISSN 1941-3297 ; 1941-3289
    ISSN (online) 1941-3297
    ISSN 1941-3289
    DOI 10.1161/CIRCHEARTFAILURE.120.008090
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  6. Article ; Online: COVID-19 and Heart Failure With Preserved Ejection Fraction.

    Freaney, Priya Mehta / Shah, Sanjiv J / Khan, Sadiya S

    JAMA

    2020  Volume 324, Issue 15, Page(s) 1499–1500

    MeSH term(s) COVID-19/complications ; Cardiometabolic Risk Factors ; Heart Failure/etiology ; Heart Failure/physiopathology ; Humans ; Inflammation/complications ; Stroke Volume
    Keywords covid19
    Language English
    Publishing date 2020-10-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2020.17445
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  7. Article ; Online: Association of thyroid dysfunction in individuals ≥ 65 years of age with subclinical cardiac abnormalities.

    Barasch, Eddy / Gottdiener, John / Buzkova, Petra / Cappola, Anne / Shah, Sanjiv / DeFilippi, Christopher / Gardin, Julius / Kizer, Jorge R

    The Journal of clinical endocrinology and metabolism

    2024  

    Abstract: ... tracking echocardiography.: Main outcome measure(s): Left heart myocardial deformation, circulating ...

    Abstract Context: The relationship between thyroid dysfunction and measures of myocardial disease in older individuals remains to be defined.
    Objective: To evaluate the impact of thyroid dysfunction on structure and function of the left-heart chambers and blood markers of cardiac disease.
    Design: Cross-sectional analysis.
    Setting: The Cardiovascular Health Study, a community-based cohort of older individuals recruited from four urban areas in the United States.
    Patients: Of 3163 participants studied, 2477 were euthyroid, 465 had subclinical hypothyroidism (SCH), 47 overt hypothyroidism (OH), 45 endogenous (endo) subclinical hyperthyroidism (endo-SCT), and 129 had exogenous (exo) SCT due to thyroid hormone supplementation.
    Interventions: Clinical evaluation, blood sampling and biomarker measurement, 2-dimensional and speckle-tracking echocardiography.
    Main outcome measure(s): Left heart myocardial deformation, circulating biomarkers of diastolic overload (NT-proBNP), fibrosis (sST2, gal-3), and cardiomyocyte injury (hs-cTnT).
    Results: SCH was associated with higher NT-proBNP (beta = 0.17, p = 0.004), whereas OH was associated with higher hs-cTnT (beta = 0.29, p = 0.005). There were also suggestive associations of SCH with higher sST2, as well as endo-SCT with higher gal-3 and lower (worse) left atrial reservoir strain. Left ventricular longitudinal strain and end-diastolic strain rate did not differ significantly from euthyroid participants in SCH, OH, or exo-SCT.
    Conclusions: In this free-living elderly cohort, subclinical and overt hypothyroidism were associated with abnormalities of blood biomarkers consistent with diastolic overload and myocardial necrosis respectively, whereas subclinical hyperthyroidism tended to be associated with myocardial fibrosis and decreased left atrial strain. Our findings could represent stage B heart failure and illuminate distinct aspects of the pathobiology of heart disease related to thyroid gland dysfunction with potential clinical implications.
    Language English
    Publishing date 2024-01-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgae001
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  8. Article ; Online: Embarking upon atrial fibrillation management in heart failure with preserved ejection fraction: Charting a course.

    Patel, Ravi B / Passman, Rod S / Shah, Sanjiv J

    Journal of cardiovascular electrophysiology

    2020  Volume 31, Issue 9, Page(s) 2284–2287

    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/therapy ; Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Prognosis ; Stroke Volume
    Language English
    Publishing date 2020-07-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.14635
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    Zs.A 2863: Show issues Location:
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  9. Article: Advances in Machine Learning Approaches to Heart Failure with Preserved Ejection Fraction.

    Ahmad, Faraz S / Luo, Yuan / Wehbe, Ramsey M / Thomas, James D / Shah, Sanjiv J

    Heart failure clinics

    2022  Volume 18, Issue 2, Page(s) 287–300

    Abstract: Heart failure with preserved ejection fraction (HFpEF) represents a prototypical cardiovascular condition in which machine learning may improve targeted therapies and mechanistic understanding of pathogenesis. Machine learning, which involves algorithms ... ...

    Abstract Heart failure with preserved ejection fraction (HFpEF) represents a prototypical cardiovascular condition in which machine learning may improve targeted therapies and mechanistic understanding of pathogenesis. Machine learning, which involves algorithms that learn from data, has the potential to guide precision medicine approaches for complex clinical syndromes such as HFpEF. It is therefore important to understand the potential utility and common pitfalls of machine learning so that it can be applied and interpreted appropriately. Although machine learning holds considerable promise for HFpEF, it is subject to several potential pitfalls, which are important factors to consider when interpreting machine learning studies.
    MeSH term(s) Heart Failure/drug therapy ; Heart Failure/therapy ; Humans ; Machine Learning ; Precision Medicine ; Stroke Volume ; Ventricular Function, Left
    Language English
    Publishing date 2022-03-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2212019-1
    ISSN 1551-7136
    ISSN 1551-7136
    DOI 10.1016/j.hfc.2021.12.002
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  10. Article ; Online: Cardiac Mechanics and Kidney Function Decline in the Cardiovascular Health Study.

    Mehta, Rupal / Buzkova, Petra / Patel, Harnish / Cheng, Jeanette / Kizer, Jorge R / Gottdiener, John S / Psaty, Bruce / Khan, Sadiya S / Ix, Joachim H / Isakova, Tamara / Shlipak, Michael G / Bansal, Nisha / Shah, Sanjiv J

    Kidney360

    2023  Volume 4, Issue 5, Page(s) 622–630

    MeSH term(s) Heart ; Kidney ; Cardiovascular System
    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0000000000000100
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