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  1. Book ; Online ; E-Book: Emergency radiology of the chest and cardiovascular system

    Scaglione, Mariano / Linsenmaier, Ulrich / Schueller, Gerd / Berger, Ferco / Wirth, Stefan

    (Medical radiology)

    2017  

    Author's details Mariano Scaglione, Ulrich Linsenmaier, Gerd Schueller, Ferco Berger, Stefan Wirth editors
    Series title Medical radiology
    Language English
    Size 1 Online-Ressource (xiv, 374 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019151389
    ISBN 978-3-319-42584-9 ; 9783319425825 ; 3-319-42584-6 ; 331942582X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Emergency radiology of the abdomen

    Scaglione, Mariano / Linsenmaier, Ulrich H. / Schueller, Gerd

    imaging features and differential diagnosis for a timely management approach

    (Medical radiology : Diagnostic imaging)

    2012  

    Author's details Mariano Scaglione ; Ulrich Linsenmaier ; Gerd Schueller, ed
    Series title Medical radiology : Diagnostic imaging
    Language English
    Size XVII, 277 S. : zahlr. Ill., 260 mm x 193 mm
    Publisher Springer
    Publishing place Heidelberg u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017176979
    ISBN 978-88-470-2512-7 ; 9788847025134 ; 88-470-2512-5 ; 8847025133
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2012 A 1286 order for loan Magazin

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  3. Book ; Thesis: Basic Fibroblast growth factor aus Schilddrüsengewebe

    Linsenmaier, Ulrich H.

    biochemische, partielle, strukturelle und biologische Charakterisierung eines parakrinen Wachstumsfaktors mit mitogener Wirkung auf Endothelzellen in-vitro

    1994  

    Author's details vorgelegt von Ulrich H. Linsenmaier
    Language German
    Size V, 149 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 1994
    HBZ-ID HT006506357
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Online ; Thesis: Ganzkörper-CT Untersuchungen bei Patienten nach Polytrauma – Untersuchungen zur Strahlendosis und Potentiale zur Dosisreduktion

    Harrieder, Andreas [Verfasser] / Linsenmaier, Ulrich [Akademischer Betreuer]

    2022  

    Author's details Andreas Harrieder ; Betreuer: Ulrich Linsenmaier
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Article: CT Marker in Emergency Imaging of Acute Basilar Artery Occlusion: Thrombosis vs. Embolism.

    Mueck, Fabian / Hernandez Petzsche, Moritz / Boeckh-Behrens, Tobias / Maegerlein, Christian / Linsenmaier, Ulrich / Scaglione, Mariano / Zimmer, Claus / Ikenberg, Benno / Berndt, Maria

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 8

    Abstract: Purpose: Acute basilar artery occlusion, a neurovascular emergency leading to high rates of morbidity and mortality, is usually diagnosed by CT imaging. The outcome is partly dependent on etiology, with a worse outcome in occlusions with underlying ... ...

    Abstract Purpose: Acute basilar artery occlusion, a neurovascular emergency leading to high rates of morbidity and mortality, is usually diagnosed by CT imaging. The outcome is partly dependent on etiology, with a worse outcome in occlusions with underlying basilar artery stenosis. As this occlusion type requires a more complex angiographic therapy, this study aimed to develop new CT markers in emergency admission imaging to rapidly identify underlying stenosis. Methods: A total of 213 consecutive patients (female n = 91, age in years (mean/SD/range): 72/13/28−97), who received endovascular treatment at a single comprehensive stroke center for acute basilar artery occlusion, were included in this study. After applying strict inclusion criteria for imaging analyses, novel CT imaging markers, such as ‘absolute density loss’ (ADL) and relative thrombus attenuation (CTA-index), that measure perviousness, were assessed for n = 109 patients by use of CT-angiography and correlated to different occlusion patterns (thrombotic vs. embolic). Inter-observer agreement was assessed using an intraclass correlation coefficient for independent measures of a radiologist and a neuroradiologist. Associations between the imaging markers and clinical and interventional parameters were tested. Results: CT markers differ between the subgroups of basilar artery occlusions with and without underlying stenosis (for ADL: 169 vs. 227 HU (p = 0.03), for CTA-index: 0.55 vs. 0.70 (p < 0.001)), indicating a higher perviousness in the case of stenosis. A good inter-rater agreement was observed for ADL and CTA-index measures (ICC 0.92/0.88). For the case of embolic occlusions, a more pervious thrombus correlates to shorter time intervals, longer procedure times, and worse reperfusion success (p-values < 0.05, respectively). Conclusions: ADL and CTA-index are easy to assess in the emergency setting of acute basilar artery occlusion with the use of routinely acquired CT-angiography. They show a high potential to differentiate thrombotic from embolic occlusions, with an impact on therapeutic decisions and angiographic procedures. Measurements can be quickly performed with good reliability, facilitating implementation in clinical practice.
    Language English
    Publishing date 2022-07-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12081817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Is It Possible to Replace Conventional Radiography (CR) with a Dose Neutral Computed Tomography (CT) of the Cervical Spine in Emergency Radiology-An Experimental Cadaver Study.

    Deak, Zsuzsanna / Brummund, Lindis / Kirchhoff, Sonja / Körner, Markus / Geyer, Lucas / Mück, Fabian / Scaglione, Mariano / Reiser, Maximilian / Linsenmaier, Ulrich

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 8

    Abstract: The purpose of this experimental study on recently deceased human cadavers was to investigate whether (I) the radiation exposure of the cervical spine CT can be reduced comparable to a dose level of conventional radiography (CR); and (II) whether and ... ...

    Abstract The purpose of this experimental study on recently deceased human cadavers was to investigate whether (I) the radiation exposure of the cervical spine CT can be reduced comparable to a dose level of conventional radiography (CR); and (II) whether and which human body parameters can be predictive for higher dose reduction potential (in this context).
    Materials and methods: Seventy serial CT scans of the cervical spine of 10 human cadavers undergoing postmortem virtual autopsy were taken using stepwise decreasing upper limits of the tube current (300 mAs, 150 mAs, 110 mAs, 80 mAs, 60 mAs, 40 mAs, and 20 mAs) at 120 kVp. An additional scan acquired at a fixed tube current of 300 mAs served as a reference. Images were reconstructed with filtered back projection and the upper (C1-4) and lower (C4-7) cervical spine were evaluated by three blinded readers for image quality, regarding diagnostic value and resolution of anatomical structures according to a semiquantitative three-point-scale. Dose values and individual physical parameters were recorded. The relationship of diagnostic IQ, dose reduction level, and patients' physical parameters were investigated. The high-contrast resolution of the applied CT protocols was tested in an additional phantom study.
    Results: The IQ of the upper cervical spine was diagnostic at 1.69 ± 0.58 mGy (CTDI) corresponding to 0.20 ± 0.07 mSv (effective dose) in all cadavers. IQ of the lower cervical spine was diagnostic at 4.77 ± 1.86 mGy corresponding to 0.560 ± 0.21 mSv (effective dose) in seven cadavers and at 2.60 ± 0.93 mGy corresponding to 0.31 ± 0.11 mSv in four cadavers. Significant correlation was detected for BMI (0.8366;
    Conclusions: Conventional radiography can be replaced with a nearly dose-neutral CT scan of the cervical spine.
    Language English
    Publishing date 2022-08-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12081872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; Thesis: Untersuchungen zum dosisneutralen Ersatz der Projektionsradiographie (CR) in der Bildgebung der HWS durch Niedrigdosis Multidetektor-Computertomographie (MDCT)

    Brummund, Lindis [Verfasser] / Linsenmaier, Ulrich [Akademischer Betreuer]

    eine experimentelle Studie

    2017  

    Author's details Lindis Brummund ; Betreuer: Ulrich Linsenmaier
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
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  8. Article ; Online: Imaging minor head injury (MHI) in emergency radiology: MRI highlights additional intracranial findings after measurement of trauma biomarker S-100B in patients with normal CCT.

    Linsenmaier, Ulrich / Wirth, Stefan / Kanz, Karl-Georg / Geyer, Lucas L

    The British journal of radiology

    2016  Volume 89, Issue 1061, Page(s) 20150827

    Abstract: Objective: To investigate whether MRI in emergency radiology can detect (a) additional trauma-related findings after minor head injury (MHI) or (b) structural, non-trauma-related intracranial lesions when trauma biomarker S-100B concentration is raised, ...

    Abstract Objective: To investigate whether MRI in emergency radiology can detect (a) additional trauma-related findings after minor head injury (MHI) or (b) structural, non-trauma-related intracranial lesions when trauma biomarker S-100B concentration is raised, or clinical symptoms are unexplained, or both.
    Methods: 41 patients with MHI were included. Concentrations of S-100B in serum were measured and categorized using an established cut-off at 0.1 μg l(-1). Intracerebral trauma-related as well as non-trauma-related chronic structural findings (atrophy, microangiopathy and chronic parenchymal defects) were assessed by cranial CT (CCT) and MRI by two independent radiologists (UL and LLG). All CCT and MRI results were compared with biomarker S-100B.
    Results: Compared with CCT, MRI detected 10 additional lesions. 5 patients had abnormal MRI with a total of 15 trauma-related lesions and showed elevated S-100B concentrations. Although sensitivity of S-100B was 100%, specificity was only 25%. Patients with structural brain lesions showed significantly higher S-100B serum levels (0.50 and 0.14 μg l(-1), p = 0.01).
    Conclusion: Biomarker S-100B has proven its high negative-predictive value to rule out intracranial bleeding in patients after MHI even if MRI is used as imaging modality. Regarding the low specificity of S-100B, structural lesions of the brain parenchyma not related to the acute trauma may be associated with increased serum concentrations of protein S-100B.
    Advances in knowledge: Biomarker S-100B has a high negative-predictive value to rule out intracranial bleeding after MHI. Biomarker S-100B's low specificity may be associated with non-traumatic brain parenchyma lesions. MRI is superior to CCT in detecting subtle findings in neuroimaging after MHI. Biomarker S-100B can potentially reduce the large number of normal CCT studies after MHI.
    MeSH term(s) Biomarkers/blood ; Brain/diagnostic imaging ; Brain/pathology ; Craniocerebral Trauma/blood ; Craniocerebral Trauma/diagnosis ; Emergency Medical Services ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Observer Variation ; Reproducibility of Results ; S100 Calcium Binding Protein beta Subunit/blood ; Sensitivity and Specificity ; Tomography, X-Ray Computed
    Chemical Substances Biomarkers ; S100 Calcium Binding Protein beta Subunit
    Language English
    Publishing date 2016
    Publishing country England
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20150827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Conference proceedings: Future: Trauma- und Notfallradiologie morgen – Was bringt die Zukunft?

    Linsenmaier, U

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2012  

    Abstract: ... Institut für Klinische Radioologie, Nussbaumstr 20, 80336 München E-Mail: Ulrich.Linsenmaier@med.uni ... for many other emergency indications of radiological imaging as well. Korrespondierender Autor: Linsenmaier U LMU München ...

    Event/congress 93. Deutscher Röntgenkongress, Hamburg, 2012
    Abstract Lernziele/Themen: Massiver Anstieg der Anzahl bildgebender Untersuchungen in der Notfallmedizin: Herausforderung Konsequenzen und Ausblick für die Radiologie Aktuelle und zukünftige Positionierung der radiologischen Notfalldiagnostik/Emergency Radiology in interdisziplinären Teams: Organisationsstruktur in spezialisierten Zentren und in Versorgungskrankenhäusern. Aktuelle und zukünftige Anforderungen an die personelle und apparative Ausstattung. in der Notfallradiologie/Emergency Radiology Trade off zwischen (Sub-) Spezialisierung in der Radiologie mit Ausbildung von Schwerpunkten (Notfallradiologie/Emergency Radiology) und den Erfordernissen der allgemeinen Versorgung Zukünftige Entwicklung der Notfallradiologie in Forschung und Lehre, Rolle der European Society of Emergency Radiology (ESER)
    Lernziele: Background: The use of crossectional imaging modalities MDCT and MRI have dramatically risen in emergency imaging mostly due to their now wider availability, shorter scan time, robust technique and high spatial and temporal resolution. Emergency medicine very much relies today on the early and comprehesive use of these imaging modalities. In recent years, the number of CT scans has exceeded 70 millions per year in the US [1]. While the emergency department patient volumes grew there at about 13% between 2000 and 2005, the number of CT examinations increased by 51% –463%, depending on the institution and the relevant body region resulting in a doubling time of emergency CT studies of only 4 years [1,2]. In multiple trauma, acute abdomen, acute chest pain and stroke MDCT is widely accepted as the imaging procedure of choice [3–4]. A detailed analysis has in a first clinical outcome study proven that standardized whole-body CT (WBCT) e.g. in polytrauma clearly improves the survival rate after severe trauma [5]. In the future similar results can be expected for many other emergency indications of radiological imaging as well. Korrespondierender Autor: Linsenmaier U LMU München, Institut für Klinische Radioologie, Nussbaumstr 20, 80336 München E-Mail: Ulrich.Linsenmaier@med.uni-muenchen.de
    Language German
    Publishing date 2012-04-25
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/s-0032-1310615
    Database Thieme publisher's database

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  10. Article ; Conference proceedings: Typische Verletzungen bei Polytrauma – Was muss und was kann erkannt werden?

    Linsenmaier, U

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2011  

    Abstract: ... Linsenmaier U LMU München, Institut für Klinische Radioologie, Nussbaumstr 20, 80336 München E-Mail: Ulrich ... Linsenmaier@med.uni-muenchen.de ...

    Event/congress 92. Deutscher Röntgenkongress und 6. Gemeinsamer Kongress der DRG und ÖRG, Hamburg, 2011
    Abstract Die radiologische Diagnostik bei Polytraumata stellt an die Radiologie besondere Herausforderungen. Unverzüglich müssen alle wesentlichen und lebensbedrohlichen Verletzungen erkannt und priorisiert werden. Nachrangige Verletzungen und Nebenbefunde müssen davon differenziert werden und dürfen die strukturierten diagnostischen und therapeutischen Maßnahmen in der frühen klinischen Behandlungsphase nicht behindern. Es muss sichergestellt sein, dass nichts Wesentliches übersehen wird, was zu einem anderen Therapiemanagement führen könnte. Hierbei haben sich Algorithmen bewährt, die die klinische Versorgung und die Diagnostik sinnvoll koordinieren. Die MDCT wird in modernen Traumzentren bereits zur Primary Patient Survey (nach ATLS) eingesetzt. Die Bildbefundung selbst sollte strukturiert erfolgen, um in Stresssituationen und bei Einsatz weniger erfahrener Radiologen eine adäquate Befundqualität sicherzustellen. Voraussetzung hierfür ist die Kenntnis typischer und atypischer seltener Verletzungsmuster. Diese werden systematisch von Kopf- bis Fuß dargestellt, erläutert und in Zusammenhang mit dem weiteren Management gebracht. Abschließend wird noch ein Ausblick auf die Anwendungsmöglichkeiten neuer Techniken gegeben, die zwar z.T. in der Routine schon etabliert, im Schockraum aber meist noch die Ausnahme sind. Hierunter zählen Verfahren wie z.B. CT-Perfusion, EKG-gating, Dual-Energy-Techniken oder Untersuchungen unter laufender Reanimation.
    Lernziele: Systematische Befundung typischer Verletzungen der Körperregionen von Kopf bis Fuß anhand Ihrer Erscheinungsbilder in der MDCT Kenntnis seltener, aber wichtiger weiterer Verletzungen Neue Möglichkeiten in der Schockraumdiagnostik wie z.B. CT-Perfusion, EKG-gating, Dual-Energy-Techniken oder Untersuchungen unter laufender Reanimation Korrespondierender Autor: Linsenmaier U LMU München, Institut für Klinische Radioologie, Nussbaumstr 20, 80336 München E-Mail: Ulrich.Linsenmaier@med.uni-muenchen.de
    Language German
    Publishing date 2011-04-29
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/s-0031-1278803
    Database Thieme publisher's database

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