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  1. Book ; Online ; E-Book: Gigantism and acromegaly

    Stratakis, Constantine A.

    genetics, diagnosis, and treatment

    2021  

    Abstract: Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis ... ...

    Author's details Constantine A. Stratakis
    Abstract "Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies"--
    Keywords Acromegaly
    Subject code 616.47
    Language English
    Size 1 online resource (312 pages)
    Publisher Elsevier
    Publishing place London, England ; San Diego, California
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-12-814538-2 ; 0-12-814537-4 ; 978-0-12-814538-8 ; 978-0-12-814537-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Genetics of primary hyperparathyroidism, our first Batrinos' scholar review, metabolic syndrome, and quite a bit of reproductive endocrinology: a great issue.

    Stratakis, Constantine A

    Hormones (Athens, Greece)

    2024  Volume 23, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Metabolic Syndrome ; Hyperparathyroidism, Primary ; Endocrinology
    Language English
    Publishing date 2024-01-10
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2075912-5
    ISSN 2520-8721 ; 1109-3099
    ISSN (online) 2520-8721
    ISSN 1109-3099
    DOI 10.1007/s42000-023-00523-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Genetics of endocrine disorders

    Stratakis, Constantine A.

    (Endocrinology and metabolism clinics of North America ; volume 46, number 2 (June 2017))

    2017  

    Author's details editor Constantine A. Stratakis
    Series title Endocrinology and metabolism clinics of North America ; volume 46, number 2 (June 2017)
    Collection
    Language English
    Size xvi Seiten, Seite 248-592, Illustrationen
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT019411444
    ISBN 978-0-323-53005-7 ; 0-323-53005-2
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Studies on transgender medicine, exploring databases, and more on metabolic syndrome and diabetes.

    Stratakis, Constantine A

    Hormones (Athens, Greece)

    2023  Volume 22, Issue 3, Page(s) 355–356

    MeSH term(s) Humans ; Diabetes Mellitus/epidemiology ; Metabolic Syndrome/epidemiology ; Metabolic Syndrome/etiology ; Transgender Persons ; Male ; Female
    Language English
    Publishing date 2023-08-24
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 2075912-5
    ISSN 2520-8721 ; 1109-3099
    ISSN (online) 2520-8721
    ISSN 1109-3099
    DOI 10.1007/s42000-023-00478-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: From obesity in ancient times to the very latest vital research data on metabolic syndrome and other significant updates.

    Stratakis, Constantine A

    Hormones (Athens, Greece)

    2023  Volume 22, Issue 2, Page(s) 149–150

    MeSH term(s) Humans ; Metabolic Syndrome/epidemiology ; Obesity/epidemiology
    Language English
    Publishing date 2023-05-24
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 2075912-5
    ISSN 2520-8721 ; 1109-3099
    ISSN (online) 2520-8721
    ISSN 1109-3099
    DOI 10.1007/s42000-023-00452-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Using music to soothe our patients, measuring hair cortisol, and machine learning in diabetes: Prof. Batrinos would have been very happy!

    Stratakis, Constantine A

    Hormones (Athens, Greece)

    2023  Volume 22, Issue 4, Page(s) 533–535

    MeSH term(s) Humans ; Music ; Hydrocortisone ; Diabetes Mellitus ; Hair ; Machine Learning
    Chemical Substances Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2023-11-09
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2075912-5
    ISSN 2520-8721 ; 1109-3099
    ISSN (online) 2520-8721
    ISSN 1109-3099
    DOI 10.1007/s42000-023-00501-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19, diabetes mellitus type 2, endocrine genetics, and pituitary and adrenal diseases.

    Stratakis, Constantine A

    Hormones (Athens, Greece)

    2023  Volume 22, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; COVID-19 ; Diabetes Mellitus, Type 2/genetics ; Adrenal Gland Diseases ; Pituitary Diseases ; Pituitary Gland ; Endocrine System Diseases/genetics ; Diabetes Mellitus
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2075912-5
    ISSN 2520-8721 ; 1109-3099
    ISSN (online) 2520-8721
    ISSN 1109-3099
    DOI 10.1007/s42000-023-00436-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: O tempora, o mores: The Age We Live In, Machine Learning, Hypertension, and Primary Aldosteronism.

    Stratakis, Constantine A

    JACC. Asia

    2023  Volume 3, Issue 4, Page(s) 676–677

    Language English
    Publishing date 2023-08-15
    Publishing country United States
    Document type Editorial
    ISSN 2772-3747
    ISSN (online) 2772-3747
    DOI 10.1016/j.jacasi.2023.06.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Genomics and precision medicine and their impact on endocrinology.

    Stratakis, Constantine A

    Endocrine connections

    2023  Volume 12, Issue 7

    Language English
    Publishing date 2023-06-08
    Publishing country England
    Document type Editorial
    ZDB-ID 2668428-7
    ISSN 2049-3614
    ISSN 2049-3614
    DOI 10.1530/EC-23-0106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Genes and environment: An old pair in a new era.

    Stratakis, Constantine A

    Maturitas

    2023  Volume 178, Page(s) 107851

    Abstract: What is the relationship between our genes and the environment we live in with regard to health? Like the debate about nature or nurture in the determination of our personality and behavior, the issue of genes and environment has been discussed intensely ...

    Abstract What is the relationship between our genes and the environment we live in with regard to health? Like the debate about nature or nurture in the determination of our personality and behavior, the issue of genes and environment has been discussed intensely in the last two centuries. Is it Darwin or Lamarck who is right about the basic determinants of our health, especially as we age in a rapidly changing environment? Evolutionary biology as proposed by Darwin with natural selection at its core may not be able to explain almost instant adjustments of phenotypic traits to the pressures of the environment. Epigenesis, a concept that dates from Aristotle, provides a mechanism for the environment to affect variation in genetic traits that may become heritable. Indeed, Lamarck first described the inheritance of acquired characteristics. Thus, it appears that in contemporary genetics, both Darwin and Lamarck are right: environmental pressures may affect our genes through epigenetics, in ways that allow for inheritance of the changes, a Lamarckian concept; however, evolution through natural selection is the basis for incorporation (or rejection) of new traits and their sustained inheritance, a Darwinian concept. In this review, we present the synthesis of Darwin's and Lamarck's theories, the only way to understand how our health, and that of our progeny, responds to challenging and fast-changing environmental cues. In addition, we present other examples of environment-driven changes in disease frequency or expression.
    MeSH term(s) Humans ; Biological Evolution ; Epigenesis, Genetic ; Phenotype ; Selection, Genetic
    Language English
    Publishing date 2023-09-26
    Publishing country Ireland
    Document type Review ; Journal Article
    ZDB-ID 80460-5
    ISSN 1873-4111 ; 0378-5122
    ISSN (online) 1873-4111
    ISSN 0378-5122
    DOI 10.1016/j.maturitas.2023.107851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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