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Book ; Online: DAVID

Wu, Junru / Yu, Xiang / Liu, Ding / Chandraker, Manmohan / Wang, Zhangyang

Dual-Attentional Video Deblurring

2019

Abstract: Blind video deblurring restores sharp frames from a blurry sequence without any prior. It is a challenging task because the blur due to camera shake, object movement and defocusing is heterogeneous in both temporal and spatial dimensions. Traditional ... ...

Abstract	Blind video deblurring restores sharp frames from a blurry sequence without any prior. It is a challenging task because the blur due to camera shake, object movement and defocusing is heterogeneous in both temporal and spatial dimensions. Traditional methods train on datasets synthesized with a single level of blur, and thus do not generalize well across levels of blurriness. To address this challenge, we propose a dual attention mechanism to dynamically aggregate temporal cues for deblurring with an end-to-end trainable network structure. Specifically, an internal attention module adaptively selects the optimal temporal scales for restoring the sharp center frame. An external attention module adaptively aggregates and refines multiple sharp frame estimates, from several internal attention modules designed for different blur levels. To train and evaluate on more diverse blur severity levels, we propose a Challenging DVD dataset generated from the raw DVD video set by pooling frames with different temporal windows. Our framework achieves consistently better performance on this more challenging dataset while obtaining strongly competitive results on the original DVD benchmark. Extensive ablative studies and qualitative visualizations further demonstrate the advantage of our method in handling real video blur. Comment: Accepted in WACV 2020
Keywords	Computer Science - Computer Vision and Pattern Recognition
Subject code	006
Publishing date	2019-12-07
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Study for Some Eccentricity-based Topological Indices of Second Type of Dominating David-derived Network.

Liu, Jia-Bao / Ali, Haidar / Ali, Didar Abdulkhaleq / Umer, Ayesha / Ali, Parvez / Kirmani, Syed Ajaz K

Combinatorial chemistry & high throughput screening

2023

Abstract: Background: Dominating David-derived networks are widely studied due to their fractal nature ... of dominating David-derived derived network. Thermodynamic characteristics, physicochemical properties, and ... of dominating David-derived network, denoted as D_2 (m).: Conclusion: These calculations will assist ...

Abstract	Background: Dominating David-derived networks are widely studied due to their fractal nature, with applications in topology, chemistry, and computer sciences. The use of molecular structure descriptors is a standard procedure that is used to correlate the biological activity of molecules with their chemical structures, which can be useful in the field of pharmacology. Objective: This article's goal is to develop analytically closed computing formulas for eccentricity-based descriptors of the second type of dominating David-derived derived network. Thermodynamic characteristics, physicochemical properties, and chemical and biological activities of chemical graphs are just a few of the many properties that may be determined using these computation formulas. Methods: Vertex sets were initially divided according to their degrees, eccentricities, and cardinalities of occurrence. The eccentricity-based indices are then computed using some combinatorics and these partitions. Results: Total eccentricity, average eccentricity, and the Zagreb index are distance-based topological indices utilized in this study for the second type of dominating David-derived network, denoted as D_2 (m). Conclusion: These calculations will assist the readers in estimating the fractal and difficult-to-handle thermodynamic and physicochemical aspects of chemical structure. Apart from configuration and impact resistance, the D_2 (m) design has been used for fundamental reasons in a variety of technical and scientific advancements.
Language	English
Publishing date	2023-08-31
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2064785-2
ISSN	1875-5402 ; 1386-2073
ISSN (online)	1875-5402
ISSN	1386-2073
DOI	10.2174/1386207326666230831125646
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Article ; Online: Robust Behavior of Charge Density Wave Quantum Motif Star-of-David in 2D NbSe

Song, Xuan / Huang, Xinyu / Yang, Han / Jia, Liangguang / Zhang, Quanzhen / Huang, Yuan / Wu, Xu / Liu, Liwei / Gao, Hong-Jun / Wang, Yeliang

Small (Weinheim an der Bergstrasse, Germany)

2023 Volume 19, Issue 52, Page(s) e2305159

Abstract: Charge density wave (CDW) is a typical collective phenomenon, and the phase change is generally accompanied by electronic transition with potential device applications. For the continuous miniaturization of devices, it is important to investigate the ... ...

Abstract	Charge density wave (CDW) is a typical collective phenomenon, and the phase change is generally accompanied by electronic transition with potential device applications. For the continuous miniaturization of devices, it is important to investigate the size effect down to the nanoscale. In this work, single-layer (SL) 1T-NbSe
Language	English
Publishing date	2023-08-27
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2168935-0
ISSN	1613-6829 ; 1613-6810
ISSN (online)	1613-6829
ISSN	1613-6810
DOI	10.1002/smll.202305159
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Article ; Online: A novel NFKB2 mutation in a Chinese patient with DAVID syndrome.

Xiao, Bing / Fang, Di / Liu, Huili / Wang, Lili / Qiu, Wenjuan

Gene

2018 Volume 687, Page(s) 319–322

MeSH term(s)	Asian Continental Ancestry Group/genetics ; Child ; China ; Common Variable Immunodeficiency/genetics ; Humans ; Male ; Mutation ; NF-kappa B p52 Subunit/genetics ; NF-kappa B p52 Subunit/metabolism ; Pedigree ; Pituitary Diseases/genetics ; Syndrome ; Whole Exome Sequencing/methods
Chemical Substances	NF-kappa B p52 Subunit ; NFKB2 protein, human
Language	English
Publishing date	2018-12-29
Publishing country	Netherlands
Document type	Case Reports ; Letter
ZDB-ID	391792-7
ISSN	1879-0038 ; 0378-1119
ISSN (online)	1879-0038
ISSN	0378-1119
DOI	10.1016/j.gene.2018.12.050
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Article ; Online: Statistics and Calculation of Entropy of Dominating David Derived Networks

Xuemei Zhao / Haidar Ali / Bilal Ali / Muhammad Ahsan Binyamin / Jia-Bao Liu / Ali Raza

Complexity, Vol

2021 Volume 2021

Abstract: ... of probability on its vertex set. In the theory of information, graph entropy has its origins. Dominating David ... administration. In this study, we discuss dominating David derived network of type 1, 2, and 3 written as D1n ...

Abstract	A graph’s entropy is a functional one, based on both the graph itself and the distribution of probability on its vertex set. In the theory of information, graph entropy has its origins. Dominating David derived networks have a variety of important applications in medication store, hardware, and system administration. In this study, we discuss dominating David derived network of type 1, 2, and 3 written as D1n, D2n, and D3n, respectively of order n. We also compute some degree-based entropies such as Randić, ABC, and GA entropy of D1n, D2n, and D3n.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: DAVID Knowledgebase

Baseler Michael W / Stephens Robert / Liu David / Bour Stephan / Guo Yongjian / Tan Qina / Huang Da / Sherman Brad T / Lane H Clifford / Lempicki Richard A

BMC Bioinformatics, Vol 8, Iss 1, p

a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis

2007 Volume 426

Abstract: ... knowledgebase is in demand for high throughput gene functional analysis. Description The DAVID Knowledgebase is ... built around the DAVID Gene Concept, a single-linkage method to agglomerate tens of millions of gene ... protein identifiers from a variety of public genomic resources into DAVID gene clusters. The grouping ...

Abstract	Abstract Background Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by many independent groups. Analysts usually need to visit many of these bioinformatics databases in order to integrate comprehensive annotation information for their genes, which becomes one of the bottlenecks, particularly for the analytic task associated with a large gene list. Thus, a highly centralized and ready-to-use gene-annotation knowledgebase is in demand for high throughput gene functional analysis. Description The DAVID Knowledgebase is built around the DAVID Gene Concept, a single-linkage method to agglomerate tens of millions of gene/protein identifiers from a variety of public genomic resources into DAVID gene clusters. The grouping of such identifiers improves the cross-reference capability, particularly across NCBI and UniProt systems, enabling more than 40 publicly available functional annotation sources to be comprehensively integrated and centralized by the DAVID gene clusters. The simple, pair-wise, text format files which make up the DAVID Knowledgebase are freely downloadable for various data analysis uses. In addition, a well organized web interface allows users to query different types of heterogeneous annotations in a high-throughput manner. Conclusion The DAVID Knowledgebase is designed to facilitate high throughput gene functional analysis. For a given gene list, it not only provides the quick accessibility to a wide range of heterogeneous annotation data in a centralized location, but also enriches the level of biological information for an individual gene. Moreover, the entire DAVID Knowledgebase is freely downloadable or searchable at http://david.abcc.ncifcrf.gov/knowledgebase/ .
Keywords	Computer applications to medicine. Medical informatics ; R858-859.7 ; Biology (General) ; QH301-705.5
Subject code	004
Language	English
Publishing date	2007-11-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Professor David Ball: prophylactic cranial irradiation (PCI) benefits patients with SCLC.

Liu, Macy

Translational lung cancer research

2018 Volume 7, Issue Suppl 1, Page(s) S81–S82

Language	English
Publishing date	2018-03-06
Publishing country	China
Document type	News
ZDB-ID	2754335-3
ISSN	2226-4477 ; 2218-6751
ISSN (online)	2226-4477
ISSN	2218-6751
DOI	10.21037/tlcr.2018.01.12
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Article ; Online: Integrated strategy for anti-fatigue markers screening of gonads of Rana temporaria chensinensis David based on comprehensive chemical analysis and in vivo activity

Wang, Zhongyao / Liu, Yunhe / Zhou, Yue / Wang, Shihan / Xu, Xinxin / Fan, Xuanrui / Chen, Miao / Yang, Yong / Wang, Zhihan / Wang, Yongsheng

Journal of Functional Foods. 2023 Aug., v. 107 p.105680-

2023

Abstract: This work is the first attempt to reveal the chemical compositions, as well as the relationships between the chemical compositions and anti-fatigue effect of Oviductus Ranae (OR) and Rana chensinensis ovum (RCO). In this work, an integrated strategy was ... ...

Abstract	This work is the first attempt to reveal the chemical compositions, as well as the relationships between the chemical compositions and anti-fatigue effect of Oviductus Ranae (OR) and Rana chensinensis ovum (RCO). In this work, an integrated strategy was applied containing comprehensive chemical profiling analysis, extraction methods, in vivo study, multivariate statistics, and network pharmacology. Here, 138 compounds were identified or briefly characterized using UPLC-Q/TOF-MS. About 24 and 35 variables were considered to be discriminating compounds from petroleum ether and ethanol extracts of OR and RCO, respectively. In addition, 41 identified compounds in OR and RCO were significantly correlated with anti-fatigue parameters. Finally, 22 candidate markers in OR and RCO were screened. Network pharmacology analysis was employed to verify those markers and screen the potential targets for anti-fatigue effect. Screened targets were further validated using RT-PCR. In muscle tissues, AKT mRNA, PI3K mRNA, and mTOR mRNA were upregulated following OR and RCO administration. This work not only paved the way for further study of OR and RCO in anti-fatigue function, but also provided essential information for their products quality control.
Keywords	Rana chensinensis ; chemical analysis ; ethanol ; multivariate analysis ; muscles ; ova ; petroleum ; pharmacology ; phosphatidylinositol 3-kinase ; quality control ; Oviductus Ranae ; Rana chensinensis ovum ; Chemical compositon ; Activity marker ; OR ; RCO ; UPLC-Q/TOF-MS ; ANOVA ; s.e.m ; EPA ; ALA ; DHA ; AA ; DPA ; LA ; OA ; PG ; TX ; Rv ; HODE ; DiHETE ; LT ; HDPA ; HDHA ; LX ; HpEPE ; NP ; HpDoHE ; KODE ; HEPE ; HETE ; oxo-ETE ; EpOME ; HpETE ; EpETrE ; LPC ; PC ; LPE ; PE
Language	English
Dates of publication	2023-08
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	2511964-3
ISSN	1756-4646
ISSN	1756-4646
DOI	10.1016/j.jff.2023.105680
Database	NAL-Catalogue (AGRICOLA)

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Article: Effect of Different Dietary Regimes on the Gut Microbiota and Fecal Metabolites of Père David’s Deer

Zhen, Junai / Ren, Yijun / Zhang, Huidan / Yuan, Xueli / Wang, Libo / Shen, Hua / Liu, Ping / Chen, Yuqing

Animals. 2022 Feb. 25, v. 12, no. 5

2022

Abstract: ... David’s deer in Dafeng Reserve will contribute greatly to Père David’s deer’s protection ... combined with tandem mass spectrometry, the gut microbiota and fecal metabolites of Père David’s deer under ... PLANT diets, suggesting that the COMB diet had more of an effect on the metabolism of Père David’s deer ...

Abstract	A deep understanding of the effect of seasonal dietary changes on the nutrition and health of Père David’s deer in Dafeng Reserve will contribute greatly to Père David’s deer’s protection. In this reserve, there were three seasonal dietary regimes: feeding on naturally occurring plants (PLANT diet), silage (SILAGE diet), and a combination of natural plants and silage (COMB diet). To some extent, the COMB diet reflects the seasonal transition from silage to the all-natural plant diet, especially in early spring. However, little is known regarding the gut microbiota changes and metabolic consequences under the COMB diet. Based on 16S rRNA sequencing and ultra-high performance liquid chromatography combined with tandem mass spectrometry, the gut microbiota and fecal metabolites of Père David’s deer under these three diets were compared. Results showed the alpha diversity of the gut microbiota was significantly lower under the COMB diet compared to either the SILAGE or PLANT diets. Although no significant changes were observed in the core phyla, Firmicutes and Bacteroidetes, among the three dietary regimes, a significant lower abundance of several other phyla (Spirochaetes, Melainabacteria, Proteobacteria, and Verrucobacteria) was observed in the COMB diet compared to the SILAGE diet. A greater number of fecal metabolite differences was identified between the COMB and SILAGE or COMB and PLANT diets than between the SILAGE and PLANT diets, suggesting that the COMB diet had more of an effect on the metabolism of Père David’s deer. The integrated pathway analysis showed that several metabolic pathways were significantly affected by the different dietary regimes, such as tryptophan metabolism, vitamin metabolism, and the platelet activation pathways. These metabolic changes reflect the responses and adaptations of Père David’s deer to different diets. Taken overall, our data reveal the difference in the gut microbiota and metabolic pathways of Père David’s deer under three dietary regimes in Dafeng Reserve, which provides important information for Père David’s deer conservation.
Keywords	Bacteroidetes ; Firmicutes ; Proteobacteria ; Spirochaetes ; diet ; intestinal microorganisms ; metabolites ; platelet activation ; silage ; species diversity ; spring ; tandem mass spectrometry ; tryptophan ; ultra-performance liquid chromatography ; vitamin metabolism
Language	English
Dates of publication	2022-0225
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani12050584
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Effect of Different Dietary Regimes on the Gut Microbiota and Fecal Metabolites of Père David’s Deer

Junai Zhen / Yijun Ren / Huidan Zhang / Xueli Yuan / Libo Wang / Hua Shen / Ping Liu / Yuqing Chen

Animals, Vol 12, Iss 584, p

2022 Volume 584

Abstract	A deep understanding of the effect of seasonal dietary changes on the nutrition and health of Père David’s deer in Dafeng Reserve will contribute greatly to Père David’s deer’s protection. In this reserve, there were three seasonal dietary regimes: feeding on naturally occurring plants (PLANT diet), silage (SILAGE diet), and a combination of natural plants and silage (COMB diet). To some extent, the COMB diet reflects the seasonal transition from silage to the all-natural plant diet, especially in early spring. However, little is known regarding the gut microbiota changes and metabolic consequences under the COMB diet. Based on 16S rRNA sequencing and ultra-high performance liquid chromatography combined with tandem mass spectrometry, the gut microbiota and fecal metabolites of Père David’s deer under these three diets were compared. Results showed the alpha diversity of the gut microbiota was significantly lower under the COMB diet compared to either the SILAGE or PLANT diets. Although no significant changes were observed in the core phyla, Firmicutes and Bacteroidetes, among the three dietary regimes, a significant lower abundance of several other phyla (Spirochaetes, Melainabacteria, Proteobacteria, and Verrucobacteria) was observed in the COMB diet compared to the SILAGE diet. A greater number of fecal metabolite differences was identified between the COMB and SILAGE or COMB and PLANT diets than between the SILAGE and PLANT diets, suggesting that the COMB diet had more of an effect on the metabolism of Père David’s deer. The integrated pathway analysis showed that several metabolic pathways were significantly affected by the different dietary regimes, such as tryptophan metabolism, vitamin metabolism, and the platelet activation pathways. These metabolic changes reflect the responses and adaptations of Père David’s deer to different diets. Taken overall, our data reveal the difference in the gut microbiota and metabolic pathways of Père David’s deer under three dietary regimes in Dafeng Reserve, which ...
Keywords	silage ; combination diet ; metabolic pathway ; nutrition ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
Subject code	590
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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