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  1. Article ; Online: Correction: ClearSight™ finger cuff versus invasive arterial pressure measurement in patients with body mass index above 45 kg/m

    Eley, Victoria / Christensen, Rebecca / Guy, Louis / Wyssusek, Kerstin / Pelecanos, Anita / Dodd, Benjamin / Stowasser, Michael / van Zundert, Andre

    BMC anesthesiology

    2023  Volume 23, Issue 1, Page(s) 75

    Language English
    Publishing date 2023-03-10
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2091252-3
    ISSN 1471-2253 ; 1471-2253
    ISSN (online) 1471-2253
    ISSN 1471-2253
    DOI 10.1186/s12871-023-02034-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: ClearSight™ finger cuff versus invasive arterial pressure measurement in patients with body mass index above 45 kg/m

    Eley, Victoria / Christensen, Rebecca / Guy, Louis / Wyssusek, Kerstin / Pelecanos, Anita / Dodd, Benjamin / Stowasser, Michael / van Zundert, Andre

    BMC anesthesiology

    2021  Volume 21, Issue 1, Page(s) 152

    Abstract: ... in patients with obesity.: Methods: Participants had a body mass index (BMI) ≥45 kg/m: Results: The 30 ... participants had a median (IQR) BMI of 50.2 kg/m: Conclusions: The vascular unloading technique was not ... before recommending this technique for intraoperative monitoring of patients with BMI ≥45 kg/m ...

    Abstract Background: Measuring blood pressure in patients with obesity is challenging. The ClearSight™ finger cuff (FC) uses the vascular unloading technique to provide continuous non-invasive blood pressure measurements. We aimed to test the agreement of the FC with invasive radial arterial monitoring (INV) in patients with obesity.
    Methods: Participants had a body mass index (BMI) ≥45 kg/m
    Results: The 30 participants had a median (IQR) BMI of 50.2 kg/m
    Conclusions: The vascular unloading technique was not adequately in agreement with radial arterial monitoring. Evaluation in a larger sample is required before recommending this technique for intraoperative monitoring of patients with BMI ≥45 kg/m
    MeSH term(s) Adult ; Aged ; Bariatric Surgery ; Blood Pressure/physiology ; Blood Pressure Determination/instrumentation ; Blood Pressure Determination/methods ; Body Mass Index ; Female ; Humans ; Male ; Middle Aged ; Monitoring, Intraoperative/instrumentation ; Monitoring, Intraoperative/methods ; Obesity/physiopathology ; Obesity/surgery ; Prospective Studies ; Radial Artery/physiology ; Reproducibility of Results ; Young Adult
    Language English
    Publishing date 2021-05-18
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091252-3
    ISSN 1471-2253 ; 1471-2253
    ISSN (online) 1471-2253
    ISSN 1471-2253
    DOI 10.1186/s12871-021-01374-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Emeritus Professor Richard D. Gordon AO, MD, PhD, FRACP 3/1/1934-4/7/2023.

    Stowasser, Michael

    Journal of human hypertension

    2023  Volume 38, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2023-09-22
    Publishing country England
    Document type Editorial
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-023-00858-2
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    Zs.A 2380: Show issues Location:
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  4. Article ; Online: Aldosterone and Primary Aldosteronism: Star Performers in Hypertension Research.

    Stowasser, Michael

    Hypertension (Dallas, Tex. : 1979)

    2021  Volume 78, Issue 3, Page(s) 747–750

    MeSH term(s) Adrenalectomy ; Aldosterone ; Humans ; Hyperaldosteronism/diagnosis ; Hyperaldosteronism/surgery ; Hypertension
    Chemical Substances Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2021-08-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.121.17594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Aldosterone, gut microbiome and hypertension: selected papers from APCH 2019.

    Stowasser, Michael

    Journal of human hypertension

    2021  Volume 35, Issue 2, Page(s) 109

    MeSH term(s) Aldosterone ; Gastrointestinal Microbiome ; Humans ; Hypertension
    Chemical Substances Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2021-01-27
    Publishing country England
    Document type Editorial
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-020-00481-5
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  6. Article ; Online: Can unilateral forms of primary aldosteronism be excluded with confidence preoperatively by methods other than adrenal venous sampling? The search continues.

    Stowasser, Michael

    Journal of hypertension

    2020  Volume 38, Issue 7, Page(s) 1259–1261

    MeSH term(s) Adrenal Glands ; Aldosterone ; Humans ; Hyperaldosteronism/diagnosis ; Potassium
    Chemical Substances Aldosterone (4964P6T9RB) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2020-06-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 605532-1
    ISSN 1473-5598 ; 0263-6352 ; 0952-1178
    ISSN (online) 1473-5598
    ISSN 0263-6352 ; 0952-1178
    DOI 10.1097/HJH.0000000000002417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 614: Show issues

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  7. Article: Editorial: Adrenal neuroendocrine system and cardiometabolic health: pathophysiology and clinical implications.

    Thuzar, Moe / Hannah-Shmouni, Fady / Stowasser, Michael

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1295655

    MeSH term(s) Humans ; Aldosterone ; Hydrocortisone ; Neurosecretory Systems ; Cardiovascular Diseases
    Chemical Substances Aldosterone (4964P6T9RB) ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2023-10-27
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1295655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The mineralocorticoid receptor-an emerging player in metabolic syndrome?

    Thuzar, Moe / Stowasser, Michael

    Journal of human hypertension

    2021  Volume 35, Issue 2, Page(s) 117–123

    Abstract: Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular diseases, and comprises obesity, hypertension, impaired glucose metabolism and dyslipidaemia. It is well recognised that the mineralocorticoid receptor (MR) plays an ... ...

    Abstract Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular diseases, and comprises obesity, hypertension, impaired glucose metabolism and dyslipidaemia. It is well recognised that the mineralocorticoid receptor (MR) plays an important role in blood pressure regulation via its effect on salt and water retention in renal tubules, with hypertension being a key feature in primary aldosteronism patients with excess adrenal production of aldosterone, the primary ligand for MRs in the epithelial tissues. MRs are also expressed in a number of non-epithelial tissues including adipose tissue; in these tissues, glucocorticoids or cortisol can also activate MRs due to low levels of 11-beta-hydroxysteroid-dehydrogenase type 2 (11-βHSD2), the enzyme which inactivates cortisol. There is increasing evidence suggesting that over-activation of MRs plays a role in the pathophysiology of the other components of metabolic syndrome, promoting adiposity, inflammation and glucose intolerance, and that MR antagonists may confer beneficial effects on energy and substrate homeostasis and cardiometabolic diseases. This review discusses the advances in the literature shedding light on the MR as an emerging player in metabolic syndrome.
    MeSH term(s) Aldosterone ; Humans ; Hyperaldosteronism ; Hypertension ; Metabolic Syndrome ; Mineralocorticoid Receptor Antagonists ; Receptors, Mineralocorticoid
    Chemical Substances Mineralocorticoid Receptor Antagonists ; Receptors, Mineralocorticoid ; Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2021-02-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-020-00467-3
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2380: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Aldosterone-producing adenoma associated with non-suppressed renin: a case series.

    Jansen, Pieter Martijn / Stowasser, Michael

    Journal of human hypertension

    2021  Volume 36, Issue 4, Page(s) 373–380

    Abstract: Although the aldosterone/renin ratio (ARR) is the preferred screening test for primary aldosteronism (PA), patients with non-suppressed renin and a falsely negative ARR on non-interfering medications have occasionally been reported. This report describes ...

    Abstract Although the aldosterone/renin ratio (ARR) is the preferred screening test for primary aldosteronism (PA), patients with non-suppressed renin and a falsely negative ARR on non-interfering medications have occasionally been reported. This report describes the clinical characteristics and outcomes of seven patients with proven aldosterone-producing adenoma (APA) and non-suppressed renin.Chart review of seven PA patients with an APA and a non-suppressed plasma renin concentration (PRC > 8.4 mU/L) was undertaken to collect data on anthropometric and biochemical characteristics, diagnostic evaluation and postsurgical outcomes.Seven patients (two women and five men) with a proven APA had median (range) PRC, plasma aldosterone and ARR of 20 (9-43) mU/L, 750 (270-1940) pmol/L and 45 (8-62, normal <70), respectively, on non-interfering medications. Six patients had two consecutive ARR measurements and in five of them both were normal. Renal artery stenosis was carefully excluded in all patients. Further evaluation for PA was pursued because of high clinical suspicion (either hypokalaemia and/or a known adrenal mass lesion on imaging). All underwent adrenal vein sampling confirming unilateral PA which was managed by unilateral adrenalectomy. Postsurgical follow-up data either confirmed or were highly suggestive of cure of PA.Strict control of factors known to influence the ARR is crucial to avoid false-negative results. Other causes that could explain a non-suppressed renin should be excluded. In patients with a consistently non-suppressed renin further diagnostic workup for PA should be considered if clinical suspicion remains high.
    MeSH term(s) Adenoma/complications ; Adenoma/diagnosis ; Adenoma/surgery ; Adrenocortical Adenoma/complications ; Adrenocortical Adenoma/diagnosis ; Adrenocortical Adenoma/surgery ; Aldosterone ; Female ; Humans ; Hyperaldosteronism/complications ; Hyperaldosteronism/diagnosis ; Hyperaldosteronism/surgery ; Hypertension/drug therapy ; Male ; Renin
    Chemical Substances Aldosterone (4964P6T9RB) ; Renin (EC 3.4.23.15)
    Language English
    Publishing date 2021-03-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-021-00525-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  10. Article ; Online: Is It the Beginning of the End for the Recumbent Saline Infusion Test?

    Stowasser, Michael

    Hypertension (Dallas, Tex. : 1979)

    2016  Volume 68, Issue 4, Page(s) 857–858

    Language English
    Publishing date 2016-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.116.07337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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