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  1. Article ; Online: Scar, Fat, and Fibrosis: Rethinking Re-Entry.

    Tung, Roderick / Tamarappoo, Balaji / Morris, Michael F

    JACC. Clinical electrophysiology

    2023  Volume 9, Issue 8 Pt 1, Page(s) 1246–1247

    MeSH term(s) Humans ; Cicatrix/pathology ; Myocardium/pathology ; Fibrosis
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2023.06.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: From alkaline earth to coinage metal carboranyls.

    Pearce, Kyle G / Morris, Louis J / Robinson, Thomas P / Johnson, Andrew L / Mahon, Mary F / Hill, Michael S

    Dalton transactions (Cambridge, England : 2003)

    2024  Volume 53, Issue 15, Page(s) 6653–6659

    Abstract: The β-diketiminato calcium and magnesium complexes, [(BDI) ... ...

    Abstract The β-diketiminato calcium and magnesium complexes, [(BDI)Mg
    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d4dt00478g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Invasive Lobular Carcinoma: A Review of Imaging Modalities with Special Focus on Pathology Concordance.

    Pereslucha, Alicia M / Wenger, Danielle M / Morris, Michael F / Aydi, Zeynep Bostanci

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 5

    Abstract: Invasive lobular cancer (ILC) is the second most common type of breast cancer. It is characterized by a unique growth pattern making it difficult to detect on conventional breast imaging. ILC can be multicentric, multifocal, and bilateral, with a high ... ...

    Abstract Invasive lobular cancer (ILC) is the second most common type of breast cancer. It is characterized by a unique growth pattern making it difficult to detect on conventional breast imaging. ILC can be multicentric, multifocal, and bilateral, with a high likelihood of incomplete excision after breast-conserving surgery. We reviewed the conventional as well as newly emerging imaging modalities for detecting and determining the extent of ILC- and compared the main advantages of MRI vs. contrast-enhanced mammogram (CEM). Our review of the literature finds that MRI and CEM clearly surpass conventional breast imaging in terms of sensitivity, specificity, ipsilateral and contralateral cancer detection, concordance, and estimation of tumor size for ILC. Both MRI and CEM have each been shown to enhance surgical outcomes in patients with newly diagnosed ILC that had one of these imaging modalities added to their preoperative workup.
    Language English
    Publishing date 2023-03-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11050746
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Republication of "Peroneus Brevis Tenodesis: Side-to-Side or Weave?"

    Janney, Cory F / Iloanya, Michael / Morris, Randal / Panchbhavi, Vinod K

    Foot & ankle orthopaedics

    2023  Volume 8, Issue 3, Page(s) 24730114231195333

    Abstract: Background: Inversion ankle injuries are extremely common, sometimes causing injury to the peroneus brevis tendon. If more than 50% of the tendon is injured, it oftentimes requires tenodesis to the adjacent peroneus longus tendon. Both Pulvertaft (PT) ... ...

    Abstract Background: Inversion ankle injuries are extremely common, sometimes causing injury to the peroneus brevis tendon. If more than 50% of the tendon is injured, it oftentimes requires tenodesis to the adjacent peroneus longus tendon. Both Pulvertaft (PT) and side-to-side (SS) techniques have been used for joining the 2 tendons. The purpose of this study was to compare the strength and stiffness of these 2 techniques.
    Methods: Five matched pairs of cadaver ankle specimens were randomized to receive either an SS or PT tenodesis of the peroneus brevis to longus tendons. Following the tenodesis, the specimens were tested for failure load, displacement, energy absorbed at failure, and peak load. Stiffness was also calculated. Paired
    Results: There were no statistically significant differences between the SS and PT tenodesis for any of the metrics measured. For stiffness, the techniques were very similar (SS = 10.14 [4.35], PT = 12.85 [1.72]).
    Conclusion: There is no difference in failure load, displacement, energy absorbed at failure, peak load or stiffness between the PT and SS techniques for peroneal tenodesis.
    Level of evidence: Level V, cadaver study.
    Language English
    Publishing date 2023-08-19
    Publishing country United States
    Document type Journal Article
    ISSN 2473-0114
    ISSN (online) 2473-0114
    DOI 10.1177/24730114231195333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Expected Disability From Isolated Small Airway Disease.

    Holley, Aaron B / Collen, Jacob F / Morris, Michael J

    Military medicine

    2021  Volume 186, Issue 7-8, Page(s) 203–204

    MeSH term(s) Airway Obstruction ; Humans ; Pulmonary Disease, Chronic Obstructive
    Language English
    Publishing date 2021-02-22
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usab096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Role of advanced imaging with cardiac computed tomography and MRI in atrial and ventricular ablation.

    Morris, Michael F / Carlson, Chelsea / Bhagat, Abhishek

    Current opinion in cardiology

    2022  Volume 37, Issue 5, Page(s) 431–438

    Abstract: Purpose of review: Increasing evidence supports the use of advanced imaging with cardiac computed tomography (CCT) and cardiac magnetic resonance (CMR) in the work-up of patients with arrythmias being considered for ablation.: Recent findings: ... ...

    Abstract Purpose of review: Increasing evidence supports the use of advanced imaging with cardiac computed tomography (CCT) and cardiac magnetic resonance (CMR) in the work-up of patients with arrythmias being considered for ablation.
    Recent findings: Advances in imaging technology and postprocessing are facilitating the use of advanced imaging before, during and after ablation in patients with both atrial and ventricular arrhythmias.In atrial arrythmias, quantitative assessment of left atrial wall thickness on CCT and quantification of late gadolinium enhancement (LGE) on CMR identify patients more likely to develop recurrent atrial arrythmias following ablation. In addition, in patients with recurrent arrythmia post ablation, LGE CMR can potentially identify targets for repeat ablation.In ventricular arrythmias, qualitative assessment of LGE can aide in determining the optimal ablation approach and predicts likelihood of ventricular arrythmias inducibility. Quantitative assessment of LGE can identify conduction channels that can be targeted for ablation. On CCT, quantitative assessment of left ventricular wall thickness can demonstrate myocardial ridges associated with re-entrant circuits for ablation.
    Summary: This review focuses on the utility of CCT and CMR in identifying key anatomical components and arrhythmogenic substrate contributing to both atrial and ventricular arrhythmias in patients being considered for ablation. Advanced imaging has the potential to improve procedural outcomes, decrease complications and shorten procedural time.
    MeSH term(s) Atrial Fibrillation/complications ; Atrial Fibrillation/diagnostic imaging ; Atrial Fibrillation/surgery ; Catheter Ablation/methods ; Contrast Media ; Gadolinium ; Humans ; Magnetic Resonance Imaging/methods
    Chemical Substances Contrast Media ; Gadolinium (AU0V1LM3JT)
    Language English
    Publishing date 2022-07-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645186-x
    ISSN 1531-7080 ; 0268-4705
    ISSN (online) 1531-7080
    ISSN 0268-4705
    DOI 10.1097/HCO.0000000000000986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Lake Erie ice is a repository of organisms.

    Iwaloye, Opeoluwa F / Michaud, Brenna / Alloy, Tessa / D'Souza, Nigel / McKay, R Michael L / Morris, Paul / Gura, Colby / Rogers, Scott O

    Microbiology resource announcements

    2024  Volume 13, Issue 4, Page(s) e0109423

    Abstract: Organism abundance and diversity were assessed in Lake Erie ice samples using sequences derived from a combined metagenomic and metatranscriptomic analysis. The 68,417 unique sequences were from Bacteria (77.5%), Eukarya (22.3%), and Archaea (0.2%) and ... ...

    Abstract Organism abundance and diversity were assessed in Lake Erie ice samples using sequences derived from a combined metagenomic and metatranscriptomic analysis. The 68,417 unique sequences were from Bacteria (77.5%), Eukarya (22.3%), and Archaea (0.2%) and indicated diverse species of organisms from 32 bacterial, 8 eukaryotic, and 2 archaeal taxonomic groups.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.01094-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Response.

    Holley, Aaron B / McMahon, Michael J / Warren, Whittney A / Collen, Jacob F / Sherner, John H / Zeman, Joseph E / Morris, Michael J

    Chest

    2022  Volume 161, Issue 4, Page(s) e253–e254

    Language English
    Publishing date 2022-03-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.10.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: High Aspect Ratio Nanoscale Pores through BCP-Based Metal Oxide Masks and Advanced Dry Etching.

    Esmeraldo Paiva, Aislan / Gerlt, Michael S / Läubli, Nino F / Prochukhan, Nadezda / Baez Vasquez, Jhonattan Frank / Kaminski Schierle, Gabriele S / Morris, Michael A

    ACS applied materials & interfaces

    2023  Volume 15, Issue 50, Page(s) 57960–57969

    Abstract: The reliable and regular modification of the surface properties of substrates plays a crucial role in material research and the development of functional surfaces. A key aspect of this is the development of the surface pores and topographies. These can ... ...

    Abstract The reliable and regular modification of the surface properties of substrates plays a crucial role in material research and the development of functional surfaces. A key aspect of this is the development of the surface pores and topographies. These can confer specific advantages such as high surface area as well as specific functions such as hydrophobic properties. Here, we introduce a combination of nanoscale self-assembled block-copolymer-based metal oxide masks with optimized deep reactive ion etching (DRIE) of silicon to permit the fabrication of porous topographies with aspect ratios of up to 50. Following the evaluation of our procedure and involved parameters using various techniques, such as AFM or SEM, the suitability of our features for applications relying on high light absorption as well as efficient thermal management is explored and discussed in further detail.
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c09863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data.

    Darmofal, Madison / Suman, Shalabh / Atwal, Gurnit / Toomey, Michael / Chen, Jie-Fu / Chang, Jason C / Vakiani, Efsevia / Varghese, Anna M / Balakrishnan Rema, Anoop / Syed, Aijazuddin / Schultz, Nikolaus / Berger, Michael F / Morris, Quaid

    Cancer discovery

    2024  

    Abstract: Tumor type guides clinical treatment decisions in cancer, but histology-based diagnosis remains challenging. Genomic alterations are highly diagnostic of tumor type, and tumor type classifiers trained on genomic features have been explored, but the most ... ...

    Abstract Tumor type guides clinical treatment decisions in cancer, but histology-based diagnosis remains challenging. Genomic alterations are highly diagnostic of tumor type, and tumor type classifiers trained on genomic features have been explored, but the most accurate methods are not clinically feasible, relying on features derived from whole genome sequencing (WGS), or predicting across limited cancer types. We use genomic features from a dataset of 39,787 solid tumors sequenced using a clinical targeted cancer gene panel to develop Genome-Derived-Diagnosis Ensemble (GDD-ENS): a hyperparameter ensemble for classifying tumor type using deep neural networks. GDD-ENS achieves 93% accuracy for high-confidence predictions across 38 cancer types, rivalling performance of WGS-based methods. GDD-ENS can also guide diagnoses on rare type and cancers of unknown primary, and incorporate patient-specific clinical information for improved predictions. Overall, integrating GDD-ENS into prospective clinical sequencing workflows could provide clinically-relevant tumor type predictions to guide treatment decisions in real time.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2625242-9
    ISSN 2159-8290 ; 2159-8274
    ISSN (online) 2159-8290
    ISSN 2159-8274
    DOI 10.1158/2159-8290.CD-23-0996
    Database MEDical Literature Analysis and Retrieval System OnLINE

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