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  1. Article ; Online: Comment on:

    Zhao, Jiashen / Laksmi, Narasimhan Kannan / Gogna, Apoorva

    Journal of endourology

    2022  Volume 37, Issue 10, Page(s) 1162–1163

    Language English
    Publishing date 2022-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 356931-7
    ISSN 1557-900X ; 0892-7790
    ISSN (online) 1557-900X
    ISSN 0892-7790
    DOI 10.1089/end.2022.0498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: IR management of portal hypertension complications.

    Gogna, Apoorva / Tan, Hiang Keat / Too, Chow Wei / Chang Pik Eu, Jason

    Clinical liver disease

    2023  Volume 22, Issue 2, Page(s) 75–79

    Language English
    Publishing date 2023-09-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2657644-2
    ISSN 2046-2484
    ISSN 2046-2484
    DOI 10.1097/CLD.0000000000000077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Vascular complications related to image-guided percutaneous thermal ablation of hepatic tumors

    Tashi, Sonam / Gogna, Apoorva / Leong, Sum / Venkatanarasimha, Nanda / Chandramohan, Sivanathan

    Diagnostic and interventional radiology (Ankara, Turkey)

    2023  Volume 29, Issue 2, Page(s) 318–325

    Abstract: Percutaneous thermal ablation of hepatic tumors is accepted as a safe, reliable, and cost-effective therapeutic option for treating hepatocellular carcinoma and hepatic metastases. However, operators should be familiar with the myriad of vascular and non- ...

    Abstract Percutaneous thermal ablation of hepatic tumors is accepted as a safe, reliable, and cost-effective therapeutic option for treating hepatocellular carcinoma and hepatic metastases. However, operators should be familiar with the myriad of vascular and non-vascular complications that can occur post-ablation and that are described in the literature. This review will focus on the various vascular complications related to percutaneous thermal ablation of hepatic tumors and discuss strategies to avoid and manage these complications.
    MeSH term(s) Humans ; Catheter Ablation/adverse effects ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/surgery ; Liver Neoplasms/pathology ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/surgery ; Carcinoma, Hepatocellular/pathology ; Treatment Outcome
    Language English
    Publishing date 2023-03-13
    Publishing country Turkey
    Document type Review ; Journal Article
    ZDB-ID 2184145-7
    ISSN 1305-3612 ; 1305-3612
    ISSN (online) 1305-3612
    ISSN 1305-3612
    DOI 10.5152/dir.2022.21809
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Use of the triple coaxial (triaxial) microcatheter system in superselective arterial embolisation for complex interventional cases: an initial experience with the system.

    Tashi, Sonam / Tan, Zehao / Gogna, Apoorva

    CVIR endovascular

    2022  Volume 5, Issue 1, Page(s) 67

    Abstract: Learning objective: To share our experience in utilising the triple coaxial (triaxial) system in superselective cannulation of arteries for complex embolisation procedures.: Background: Percutaneous transcatheter selective embolisation is widely ... ...

    Abstract Learning objective: To share our experience in utilising the triple coaxial (triaxial) system in superselective cannulation of arteries for complex embolisation procedures.
    Background: Percutaneous transcatheter selective embolisation is widely performed for a myriad of oncologic (e.g., trans-arterial chemo- or radio-embolisation) and non-oncologic (e.g., for embolisation of bleeding and benign conditions such as uterine fibroid and benign prostate hyperplasia) purposes. The cornerstone of such embolisation procedures is to achieve superselective cannulation of the arterial supply to the tumour/organ, preventing the complication of non-target embolisation. However, a multitude of factors, such as complex vascular anatomy, can pose challenges to achieving this goal.
    Clinical findings/procedural details: The triaxial system utilises two smaller microcatheters telescoped through each other over a microwire. We have adopted the triaxial system for specific cases due to its perceived superior torquability and trackability compared to the conventional coaxial system, in which superselective cannulation is anticipated to be challenging. The triaxial system is also favourable in situations where the inner microcatheter needs to be "sacrificed" after administering the embolics (e.g., after administering radioisotopes in radioembolisation, N-butyl cyanoacrylate [NBCA] glue or ethylene-vinyl alcohol copolymer [EvOH] Onyx). Through a case series with procedural details such as fluoroscopic time, contrast administered, etc., we hope to illustrate the utility and efficacy of the triaxial system as well as present pitfalls in its usage.
    Conclusion: The triaxial system appears to be a valuable system for certain complex embolisation procedures and could be better suited than the conventional coaxial systems in these specific circumstances.
    Language English
    Publishing date 2022-12-23
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2520-8934
    ISSN (online) 2520-8934
    DOI 10.1186/s42155-022-00340-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Hybrid operating room with ceiling mounted imaging system assisted pre-operative and intra-operative lung nodule localization for thoracoscopic resections: a 5-year case series.

    Chia, Audrey Qi Xin / Gogna, Apoorva / Pena, Angela Maria Takano / Sai, Vishnu Vemula Sri / Chandramohan, Sivanathan / Chan, Shaun Ju Min Xavier / Ong, Boon-Hean

    Journal of cardiothoracic surgery

    2024  Volume 19, Issue 1, Page(s) 85

    Abstract: Background: Video-assisted thoracoscopic (VATS) lung resections are increasingly popular and localization techniques are necessary to aid resection. We describe our experience with hybrid operating room (OR) cone-beam computed tomography (CT) assisted ... ...

    Abstract Background: Video-assisted thoracoscopic (VATS) lung resections are increasingly popular and localization techniques are necessary to aid resection. We describe our experience with hybrid operating room (OR) cone-beam computed tomography (CT) assisted pre-operative and intra-operative lesion localization of lung nodules for VATS wedge resections, including our novel workflow using the hybrid OR cone-beam CT to re-evaluate patients who have undergone pre-operative localization for those who are unsuitable for intra-operative localization.
    Methods: Retrospective analysis of all consecutive patients with small (≤ 20 mm), deep (≥ 10 mm distance from pleura) and/or predominantly ground-glass nodules selected for lesion localization in the Interventional Radiology suite followed by re-evaluation with cone-beam CT in the hybrid OR (pre-operative), or in the hybrid OR alone (intra-operative), prior to intentional VATS wedge performed by a single surgeon at our centre from January 2017 to December 2021.
    Results: 30 patients with 36 nodules underwent localization. All nodules were successfully resected with a VATS wedge resection, although 10% of localizations had hookwire or coil dislodgement. The median effective radiation dose in the pre-operative group was 10.4 mSV including a median additional radiation exposure of 0.9 mSV in the hybrid OR for reconfirmation of hookwire or coil position prior to surgery (p = 0.87). The median effective radiation dose in the intra-operative group was 3.2 mSV with a higher mean rank than the intra-operative group, suggesting a higher radiation dose (p = 0.01).
    Conclusions: We demonstrate that our multidisciplinary approach utilizing the hybrid OR is safe and effective. Intra-operative localization is associated with lower radiation doses. Routine use of cone-beam CT to confirm the position of the physical marker prior to surgery in the hybrid OR helps mitigate consequences of localization failure with only a modest increase in radiation exposure.
    MeSH term(s) Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/surgery ; Retrospective Studies ; Operating Rooms ; Solitary Pulmonary Nodule/diagnostic imaging ; Solitary Pulmonary Nodule/surgery ; Tomography, X-Ray Computed/methods ; Thoracic Surgery, Video-Assisted/methods ; Lung/surgery
    Language English
    Publishing date 2024-02-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2227224-0
    ISSN 1749-8090 ; 1749-8090
    ISSN (online) 1749-8090
    ISSN 1749-8090
    DOI 10.1186/s13019-024-02564-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Review of outcomes of combination therapy using yttrium 90 radioembolization and sorafenib/nivolumab for HCC with hepatic vein or IVC invasion

    Shiqi Chung / Apoorva Gogna / Sivanathan Chandramohan / Richard Lo / Farah Gillan Irani / Nanda Venkatanarasimha

    Proceedings of Singapore Healthcare, Vol

    2023  Volume 32

    Abstract: Background A systematic review of the outcomes of combination therapy using Yttrium 90 radioembolization (Y90) and sorafenib/nivolumab for patients with hepatocellular carcinoma (HCC), with hepatic vein (HV) or inferior vena cava (IVC) invasion. The aim ... ...

    Abstract Background A systematic review of the outcomes of combination therapy using Yttrium 90 radioembolization (Y90) and sorafenib/nivolumab for patients with hepatocellular carcinoma (HCC), with hepatic vein (HV) or inferior vena cava (IVC) invasion. The aim of this study is to summarise the results of different studies that used the combination therapy for HCC patients with tumor thrombosis involving the HV or IVC. Method A literature search was performed using keywords in Medline and Google Scholar limited to publications from 2010 to 2021. There were 173 articles identified during the initial literature search. During abstract screening, 81 articles were excluded. Another 83 did not contain information on hepatic vein or IVC invasion. Therefore, 9 articles met the eligibility criteria and were included in the synthesis. Results In total, 37 patients with hepatic vein or IVC invasion were identified. There were 31 patients who were given sorafenib, 7 were given nivolumab and 1 was given both sorafenib and nivolumab. Among the 37 patients, 21 had hepatic vein invasion, 22 had IVC invasion and 6 had both HV and IVC invasion. The median OS was 20.55 months and median PFS was 8.18 months. For the results, 23 patients were evaluated via modified RECIST (mRECIST) criteria and 14 were evaluated via RECIST 1.1. Conclusion The combination of local and systemic therapies demonstrated potential results for increased response rates, OS and PFS benefits. Further studies are required to determine the long-term outcomes of the combination therapy for this group of patients.
    Keywords Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: The Role of Drug-Coated Balloon in Haemodialysis Arteriovenous Fistula Stenosis Management.

    Da Zhuang, Kun / Irani, Farah Gillan / Gogna, Apoorva / Too, Chow Wei / Tan, Bien Soo / Tay, Kiang Hiong

    Cardiovascular and interventional radiology

    2023  Volume 46, Issue 9, Page(s) 1144–1153

    Abstract: Arteriovenous fistula (AVF) stenosis is a common problem leading to dialysis access dysfunction. The conventional balloon (CB) is the most commonly used device during angioplasty but suffers from poor durability of results due to neointimal hyperplasia- ... ...

    Abstract Arteriovenous fistula (AVF) stenosis is a common problem leading to dialysis access dysfunction. The conventional balloon (CB) is the most commonly used device during angioplasty but suffers from poor durability of results due to neointimal hyperplasia-mediated recurrence. The drug-coated balloon (DCB) is an adjunct to balloon angioplasty that reduces neointimal hyperplasia, thereby improving post-angioplasty patency. Despite the heterogeneity of DCB clinical trials to date, the evidence suggests that DCBs of different brands are not necessarily equal, and that patient selection, adequate lesion preparation and proper DCB procedural technique are important to realize the benefit of DCB angioplasty.
    MeSH term(s) Humans ; Vascular Patency ; Graft Occlusion, Vascular/diagnostic imaging ; Graft Occlusion, Vascular/therapy ; Constriction, Pathologic ; Hyperplasia ; Cardiovascular Agents ; Coated Materials, Biocompatible ; Time Factors ; Treatment Outcome ; Arteriovenous Shunt, Surgical ; Vascular Access Devices ; Renal Dialysis ; Angioplasty, Balloon/methods ; Arteriovenous Fistula/diagnostic imaging ; Arteriovenous Fistula/therapy ; Paclitaxel
    Chemical Substances Cardiovascular Agents ; Coated Materials, Biocompatible ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-023-03497-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Radiochemical Feasibility of Mixing of

    Yang, Chang-Tong / Ngam, Pei Ing / Phua, Vanessa Jing Xin / Yu, Sidney Wing Kwong / Apoorva, Gogna / Ng, David Chee Eng / Huang, Hian Liang

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 21

    Abstract: Yttrium-90 ( ...

    Abstract Yttrium-90 (
    MeSH term(s) Humans ; Microspheres ; Technetium Tc 99m Aggregated Albumin ; Iohexol ; Feasibility Studies ; Tomography, Emission-Computed, Single-Photon/methods ; Embolization, Therapeutic/methods ; Radiopharmaceuticals ; Liver Neoplasms/diagnostic imaging
    Chemical Substances Technetium Tc 99m Aggregated Albumin ; Iohexol (4419T9MX03) ; Radiopharmaceuticals
    Language English
    Publishing date 2022-11-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27217646
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Impact of catheter tip to hepatic vein ostium distance on the validity and prognostication of hepatic venous pressure gradient in cirrhosis.

    Tan, Hiang Keat / Tan, Alfred Bingchao / Teh, Kevin Kim Jun / Gogna, Apoorva / Too, Chow Wei / Leong, Sum / Chang, Jason Pik Eu

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 16980

    Abstract: Hepatic venous pressure gradient (HVPG) is an accurate measure of portal hypertension in cirrhosis. However, the effect of catheter tip distance from hepatic vein ostium (HVO) on HVPG is unknown. We performed a retrospective study on 228 patients with ... ...

    Abstract Hepatic venous pressure gradient (HVPG) is an accurate measure of portal hypertension in cirrhosis. However, the effect of catheter tip distance from hepatic vein ostium (HVO) on HVPG is unknown. We performed a retrospective study on 228 patients with 307 HVPGs in our institution. The objectives of this study were to assess the effect of catheter position on the validity of HVPG and its prognostication in cirrhosis. In this study, free hepatic vein pressure (FHVP) was considered optimal when difference between FHVP and inferior vena cava pressure was ≤ 2 mmHg. HVPG progressively decreased (p < 0.001) when measured at increasing distance from HVO due to an increasing FHVP (p = 0.036) but an unchanged wedged hepatic vein pressure (p = 0.343). Catheter tip distance > 5 to ≤ 8 cm [odds ratio {OR} 0.16 (95% CI 0.05-0.47), p = 0.001] and > 8 cm [OR 0.14 (95% CI 0.04-0.47), p = 0.002] compared to ≤ 3 cm from HVO were independent predictors of not achieving optimal FHVP. Baseline HVPG ≥ 16 mmHg was strongly associated with deaths due to cirrhosis and liver transplantation for end-stage liver disease compared to HVPG < 16 mmHg when FHVP was optimal (p < 0.001) but not when it was suboptimal (p = 0.359). Our study showed that FHVP is spuriously elevated when measured at > 5 cm from HVO, resulting in inaccurately low HVPG.
    MeSH term(s) Humans ; Hepatic Veins ; Retrospective Studies ; Liver Cirrhosis/complications ; Fibrosis ; Portal Pressure ; Catheters
    Language English
    Publishing date 2023-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44016-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Pseudoaneurysm after vacuum-assisted breast biopsy treated with percutaneous thrombin injection.

    Xiang, Fei / Gogna, Apoorva / Leong, Lester Chee Hao / Tan, Benita Kiat Tee

    The breast journal

    2019  Volume 25, Issue 2, Page(s) 318–319

    MeSH term(s) Aneurysm, False/diagnostic imaging ; Aneurysm, False/drug therapy ; Aneurysm, False/etiology ; Biopsy, Needle/adverse effects ; Biopsy, Needle/instrumentation ; Biopsy, Needle/methods ; Breast Neoplasms/pathology ; Female ; Fibroadenoma/pathology ; Humans ; Image-Guided Biopsy ; Injections, Subcutaneous ; Mammary Arteries/diagnostic imaging ; Thrombin/administration & dosage ; Thrombin/therapeutic use ; Ultrasonography, Doppler ; Ultrasonography, Mammary ; Vacuum
    Chemical Substances Thrombin (EC 3.4.21.5)
    Language English
    Publishing date 2019-02-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1289960-4
    ISSN 1524-4741 ; 1075-122X
    ISSN (online) 1524-4741
    ISSN 1075-122X
    DOI 10.1111/tbj.13213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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