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  1. Article ; Online: Improvement in Neonatal Refractory Hypoxia by Airway Pressure Release Ventilation With a Cuffed Tube and Intracuff Pressure Monitoring

    Hirota, Azusa / Inoue, Satoki / Kawaguchi, Masahiko

    Asian journal of anesthesiology

    2019  Volume 57, Issue 4, Page(s) 130–131

    MeSH term(s) Continuous Positive Airway Pressure/methods ; Humans ; Hypoxia/therapy ; Infant, Newborn ; Male ; Pressure
    Language English
    Publishing date 2019-10-29
    Publishing country China (Republic : 1949- )
    Document type Case Reports ; Journal Article
    ISSN 2468-824X
    ISSN (online) 2468-824X
    DOI 10.6859/aja.201912_57(4).0005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Acute pancreatitis. 2. Etiology and physiopathology].

    Hirota, Masahiko

    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine

    2010  Volume 99, Issue 1, Page(s) 9–14

    MeSH term(s) Acute Disease ; Female ; Humans ; Male ; Pancreatitis/etiology ; Pancreatitis/physiopathology
    Language Japanese
    Publishing date 2010-01-13
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 952816-7
    ISSN 1883-2083 ; 0021-5384
    ISSN (online) 1883-2083
    ISSN 0021-5384
    DOI 10.2169/naika.99.9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A case of accessory hepatic duct entering cystic duct successfully treated by laparoscopic cholecystectomy for cholecystolithiasis.

    Tomita, Masahiro / Okabe, Hirohisa / Masuda, Toshiro / Ono, Asuka / Kuroda, Daisuke / Kuroki, Hideyuki / Hirota, Masahiko / Hibi, Taizo / Baba, Hideo / Sugita, Hiroki

    Asian journal of endoscopic surgery

    2023  Volume 16, Issue 3, Page(s) 546–549

    Abstract: Although laparoscopic cholecystectomy is a well-established surgical procedure, an accessory hepatic duct (AcHD) entering the cystic duct is poorly understood. A 77-year-old woman with symptomatic cholecystlithiasis was referred to our hospital. ... ...

    Abstract Although laparoscopic cholecystectomy is a well-established surgical procedure, an accessory hepatic duct (AcHD) entering the cystic duct is poorly understood. A 77-year-old woman with symptomatic cholecystlithiasis was referred to our hospital. Abdominal ultrasonography indicated several small stones in the gall bladder. Magnetic resonance cholangiopancreatography (MRCP) did not reveal an anomalous cystic duct. Dissecting the gall bladder bed at operation, AcHD entering the cystic duct was suspected. Intraoperative cholangiography revealed that B5 branch entered the cystic duct. We ligated the AcHD, and divided it. Laparoscopic cholecystectomy was completed, and the patient was discharged without any complication. A week after the operation, MRCP showed that ventral branch of B5 was dilated. The patient showed no symptom for more than a year. The present case exhibited extremely rare AcHD entering the cystic duct, which was hardly recognized before surgery. It is possible to recognize such anomalous variants with standard laparoscopic approach based on 2018 Tokyo Guidelines and with attention to the possibilities of AcHD entering the cystic duct.
    MeSH term(s) Female ; Humans ; Aged ; Cystic Duct/surgery ; Cholecystectomy, Laparoscopic/methods ; Cholecystolithiasis/complications ; Cholecystolithiasis/surgery ; Hepatic Duct, Common/surgery ; Cholangiography
    Language English
    Publishing date 2023-03-21
    Publishing country Japan
    Document type Case Reports
    ZDB-ID 2503256-2
    ISSN 1758-5910 ; 1758-5902
    ISSN (online) 1758-5910
    ISSN 1758-5902
    DOI 10.1111/ases.13175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Percutaneous transfistulous interventions for intractable pancreatic fistula.

    Hirota, Masahiko

    Radiology research and practice

    2011  Volume 2011, Page(s) 109259

    Abstract: THREE TECHNIQUES FOR THE TREATMENT OF INTRACTABLE PANCREATIC FISTULA: percutaneous transfistulous pancreatic duct drainage (PTPD), percutaneous transfistulous pancreatojejunostomy (PTPJ), and percutaneous transfistulous pancreatic duct embolization (PTPE) ...

    Abstract THREE TECHNIQUES FOR THE TREATMENT OF INTRACTABLE PANCREATIC FISTULA: percutaneous transfistulous pancreatic duct drainage (PTPD), percutaneous transfistulous pancreatojejunostomy (PTPJ), and percutaneous transfistulous pancreatic duct embolization (PTPE) are presented as treatment options for intractable pancreatic fistula. PTPD is effective for most cases of intractable fistula that communicate with the main pancreatic duct. However, PTPD itself is not enough in some specific cases. PTPJ and PTPE are applicable in such cases.
    Language English
    Publishing date 2011-03-30
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2594649-3
    ISSN 2090-195X ; 2090-1941
    ISSN (online) 2090-195X
    ISSN 2090-1941
    DOI 10.1155/2011/109259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Combined Neutrophil-to-Lymphocyte Ratio Score Is Associated With Chemotherapeutic Response and Predicts Prognosis in Patients With Advanced Pancreatic Cancer.

    Okabe, Hirohisa / Masuda, Toshiro / Tomita, Masahiro / Ono, Asuka / Ogawa, Daisuke / Kuroda, Daisuke / Kuroki, Hideyuki / Hirota, Masahiko / Hibi, Taizo / Baba, Hideo / Sugita, Hiroki

    Anticancer research

    2024  Volume 44, Issue 4, Page(s) 1575–1582

    Abstract: Background/aim: Neutrophil-to-lymphocyte ratio (NLR) is a prognostic indicator for several malignancies, including pancreatic cancer. We developed a novel combined NLR score (cNLRS) based on baseline NLR and change in NLR after chemotherapy (ΔNLR), and ... ...

    Abstract Background/aim: Neutrophil-to-lymphocyte ratio (NLR) is a prognostic indicator for several malignancies, including pancreatic cancer. We developed a novel combined NLR score (cNLRS) based on baseline NLR and change in NLR after chemotherapy (ΔNLR), and examined its prognostic value and role in chemotherapeutic response in patients with advanced pancreatic cancer.
    Patients and methods: This study retrospectively assessed 210 advanced pancreatic cancer patients receiving chemotherapy between 2010 and 2021. The cNLRS was developed and its association with chemotherapeutic response and prognosis was investigated.
    Results: The cNLRS consisted of baseline NLR ≥2.5 and ΔNLR ≥0, both of which were remained as independent poor predictors of prognosis adjusting for other traditional clinicopathological features. A high cNLRS served as an independent prognostic factor of reduced overall survival. Of note, the cNLRS was significantly associated with disease control rate and treatment duration not only in 1st line treatment but also in 2nd line treatment.
    Conclusion: The cNLRS established as a useful prognostic biomarker might be associated with chemotherapeutic response and could predict survival in advanced patients with pancreatic ductal adenocarcinoma treated with chemotherapy.
    MeSH term(s) Humans ; Neutrophils/pathology ; Retrospective Studies ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Prognosis ; Lymphocytes/pathology ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/pathology
    Language English
    Publishing date 2024-03-27
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.16955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Population-Based Study of the Incidence and Mortality Rate of Acute Aortic Dissection.

    Moriyama, Shuji / Hara, Masahiko / Hirota, Takafumi / Nakata, Kosuke / Doi, Hideki / Matsumura, Toshiyuki / Araki, Yushi / Inomata, Yukihiro / Fukui, Toshihiro

    Circulation journal : official journal of the Japanese Circulation Society

    2023  Volume 88, Issue 3, Page(s) 297–306

    Abstract: Background: Acute aortic dissection (AAD) has high morbidity and a high fatality rate for a cardiovascular disease. Recent studies suggested that the incidence of AAD is increasing. However, the actual incidence and mortality rates of AAD are not well ... ...

    Abstract Background: Acute aortic dissection (AAD) has high morbidity and a high fatality rate for a cardiovascular disease. Recent studies suggested that the incidence of AAD is increasing. However, the actual incidence and mortality rates of AAD are not well known. This study investigated the current epidemiology of AAD within the Yatsushiro medical jurisdictional area.Methods and Results: A population-based review of patients with AAD was performed in a geographically well-defined area. Data were collected retrospectively from January 2011 to December 2020 for a total of 196 patients with AAD (Stanford Type A, n=126 [64.3%]; Stanford Type B, n=70 [35.7%]). The mean patient age was 74.3 years, and 55.6% (109/196) were women. The crude and age-standardized incidence rates of AAD in our medical jurisdictional area were 13.6 and 11.4 per 100,000 inhabitants per year, respectively. The crude and age-standardized 30-day mortality rates of AAD were 4.9 and 4.0 per 100,000 inhabitants per year, respectively. There were upward tendencies for both the incidence and 30-day mortality rate of AAD with age, with both being significantly higher in patients aged ≥85 years (P<0.001).
    Conclusions: This population-based study detected a higher incidence of AAD than previous studies, but reported a lower incidence of AAD in men than in women. Increasing age was associated with an increased incidence and mortality rate of AAD.
    MeSH term(s) Male ; Humans ; Female ; Aged, 80 and over ; Aged ; Incidence ; Retrospective Studies ; Aortic Dissection/epidemiology ; Acute Disease ; Risk Factors
    Language English
    Publishing date 2023-09-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2068090-9
    ISSN 1347-4820 ; 1346-9843
    ISSN (online) 1347-4820
    ISSN 1346-9843
    DOI 10.1253/circj.CJ-23-0076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Percutaneous Transfistulous Interventions for Intractable Pancreatic Fistula

    Masahiko Hirota

    Radiology Research and Practice, Vol

    2011  Volume 2011

    Abstract: Three techniques for the treatment of intractable pancreatic fistula: percutaneous transfistulous pancreatic duct drainage (PTPD), percutaneous transfistulous pancreatojejunostomy (PTPJ), and percutaneous transfistulous pancreatic duct embolization (PTPE) ...

    Abstract Three techniques for the treatment of intractable pancreatic fistula: percutaneous transfistulous pancreatic duct drainage (PTPD), percutaneous transfistulous pancreatojejunostomy (PTPJ), and percutaneous transfistulous pancreatic duct embolization (PTPE) are presented as treatment options for intractable pancreatic fistula. PTPD is effective for most cases of intractable fistula that communicate with the main pancreatic duct. However, PTPD itself is not enough in some specific cases. PTPJ and PTPE are applicable in such cases.
    Keywords Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Factors affecting the willingness of nursing care staffs for cooperation with heart failure care and the role of internet video education

    Yoshiharu Kinugasa / Toshiaki Adachi / Masaharu Fukuki / Yutaka Hirota / Natsuko Ishiga / Masahiko Kato / Einosuke Mizuta / Emiko Mura / Yoshihito Nozaka / Hiroki Omodani / Hiroaki Tanaka / Yasunori Tanaka / Izuru Watanabe / Kazuhiro Yamamoto / Masaaki Mikami

    Journal of General and Family Medicine, Vol 25, Iss 1, Pp 19-

    2024  Volume 27

    Abstract: Abstract Background With the aging of heart failure (HF) patients, collaboration between medical and nursing care facilities is essential for HF care. The aims of this study were: (1) to identify the factors that affect willingness of nursing care staffs ...

    Abstract Abstract Background With the aging of heart failure (HF) patients, collaboration between medical and nursing care facilities is essential for HF care. The aims of this study were: (1) to identify the factors that affect willingness of nursing care staffs to cooperate with HF care; (2) to test whether the internet video education is useful in improving their willingness to collaborate. Methods A web‐based questionnaire was e‐mailed to 417 registered medical corporations that operated nursing care facilities in the prefecture where the authors work. Medical and care staff working at each facility were asked their willingness to cooperate with HF care and their problems about collaboration. Machine learning analysis was used to assess the factors associated with unwillingness to cooperate. After watching a 6‐min YouTube video explaining HF and community collaboration, we reaffirmed their willingness to cooperate. Results We received responses from 76 medical and care staff members. Before watching the video, 32.9% of participants stated that they were unwilling to cooperate with HF care. Machine learning analysis showed that job types, perceived problems of collaboration, and low opportunities to learn about HF were associated with unwillingness to cooperation. After watching the video, we observed an increase from 67.1% to 80.3% (p < 0.05) of participants willing to cooperate with HF care. Conclusions Job types, perceived problems of collaboration, and low opportunities to learn about HF are associated with unwillingness of nursing care staff for HF care. Internet videos are potential learning tool that can easily promote community collaboration for HF.
    Keywords collaborative care ; education ; internet ; Medicine (General) ; R5-920
    Subject code 650
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Preoperative serum CA19-9 predicts postoperative pancreatic fistula in PDAC patients: retrospective analysis at a single institution.

    Sugita, Hiroki / Okabe, Hirohisa / Ogawa, Daisuke / Hirao, Hiroki / Kuroda, Daisuke / Taki, Katsunobu / Tomiyasu, Shinjiro / Hirota, Masahiko

    BMC surgery

    2022  Volume 22, Issue 1, Page(s) 367

    Abstract: Background: Postoperative pancreatic fistula (POPF) is a critical complication of pancreatectomy in patients with pancreatic ductal adenocarcinoma (PDAC). Recent papers reported that serum carbohydrate antigen (CA)19-9 levels predicted long-term ... ...

    Abstract Background: Postoperative pancreatic fistula (POPF) is a critical complication of pancreatectomy in patients with pancreatic ductal adenocarcinoma (PDAC). Recent papers reported that serum carbohydrate antigen (CA)19-9 levels predicted long-term prognosis. We investigated whether preoperative serum CA19-9 levels were associated with POPF in PDAC patients.
    Methods: This cohort study was conducted at a single institution retrospectively. Clinicopathologic features were determined using medical records.
    Results: Among of 196 consecutive patients who underwent pancreatectomy against PDAC, 180 patients whose CA19-9 levels were above the measurement sensitivity, were registered in this study. The patients consisted of 122 patients who underwent pancreaticoduodenectomy and 58 patients who underwent distal pancreatectomy. Several clinicopathological factors, including CA 19-9 level, as well as surgical factors were determined retrospectively based on the medical records. Patients with high CA19-9 levels had a significantly higher incidence of POPF than those with low levels (43.9 vs. 13.0%, P < 0.0001). The receiver operating characteristic curves calculated that the cutoff CA19-9 value to predict POPF was 428 U/mL. CA19-9, BMI, curability, and histology were statistically significant risk factors for POPF by univariate analysis. Multivariate analysis showed that CA19-9 and BMI levels were statistically significant independent risk factors for POPF. CA19-9 levels were correlated with both histology and curability. Disease free survival and overall survival of patients with higher levels of CA19-9 were significantly shorter than that of patients with lower levels of preoperative serum CA19-9.
    Conclusions: In patients undergoing pancreatectomy for PDAC, higher preoperative CA19-9 levels are a significant predictor for POPF.
    MeSH term(s) Humans ; Pancreatic Fistula/diagnosis ; Pancreatic Fistula/etiology ; Pancreatic Fistula/surgery ; CA-19-9 Antigen ; Retrospective Studies ; Cohort Studies ; Carcinoma, Pancreatic Ductal/surgery ; Carcinoma, Pancreatic Ductal/pathology ; Pancreatic Neoplasms/pathology ; Pancreaticoduodenectomy/adverse effects ; Pancreatectomy/adverse effects ; Postoperative Complications/diagnosis ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Risk Factors ; Pancreatic Neoplasms
    Chemical Substances CA-19-9 Antigen
    Language English
    Publishing date 2022-10-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050442-1
    ISSN 1471-2482 ; 1471-2482
    ISSN (online) 1471-2482
    ISSN 1471-2482
    DOI 10.1186/s12893-022-01825-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Factors affecting the willingness of nursing care staffs for cooperation with heart failure care and the role of internet video education.

    Kinugasa, Yoshiharu / Adachi, Toshiaki / Fukuki, Masaharu / Hirota, Yutaka / Ishiga, Natsuko / Kato, Masahiko / Mizuta, Einosuke / Mura, Emiko / Nozaka, Yoshihito / Omodani, Hiroki / Tanaka, Hiroaki / Tanaka, Yasunori / Watanabe, Izuru / Yamamoto, Kazuhiro / Mikami, Masaaki

    Journal of general and family medicine

    2023  Volume 25, Issue 1, Page(s) 19–27

    Abstract: Background: With the aging of heart failure (HF) patients, collaboration between medical and nursing care facilities is essential for HF care. The aims of this study were: (1) to identify the factors that affect willingness of nursing care staffs to ... ...

    Abstract Background: With the aging of heart failure (HF) patients, collaboration between medical and nursing care facilities is essential for HF care. The aims of this study were: (1) to identify the factors that affect willingness of nursing care staffs to cooperate with HF care; (2) to test whether the internet video education is useful in improving their willingness to collaborate.
    Methods: A web-based questionnaire was e-mailed to 417 registered medical corporations that operated nursing care facilities in the prefecture where the authors work. Medical and care staff working at each facility were asked their willingness to cooperate with HF care and their problems about collaboration. Machine learning analysis was used to assess the factors associated with unwillingness to cooperate. After watching a 6-min YouTube video explaining HF and community collaboration, we reaffirmed their willingness to cooperate.
    Results: We received responses from 76 medical and care staff members. Before watching the video, 32.9% of participants stated that they were unwilling to cooperate with HF care. Machine learning analysis showed that job types, perceived problems of collaboration, and low opportunities to learn about HF were associated with unwillingness to cooperation. After watching the video, we observed an increase from 67.1% to 80.3% (
    Conclusions: Job types, perceived problems of collaboration, and low opportunities to learn about HF are associated with unwillingness of nursing care staff for HF care. Internet videos are potential learning tool that can easily promote community collaboration for HF.
    Language English
    Publishing date 2023-11-20
    Publishing country Japan
    Document type Journal Article
    ISSN 2189-7948
    ISSN (online) 2189-7948
    DOI 10.1002/jgf2.658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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