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  1. Article ; Online: Establishing and Sustaining the Kidney Stone Engagement Core: A Model for Patient Engagement in Benign Urologic Disease.

    Shah, Nayan / Tasian, Gregory E / Ellison, Jonathan S

    The Journal of urology

    2024  Volume 211, Issue 4, Page(s) 614–616

    MeSH term(s) Humans ; Patient Participation ; Kidney Calculi/therapy ; Kidney ; Urologic Diseases
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003842
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  2. Article ; Online: Role of Climate Change in Urologic Health: Kidney Stone Disease.

    Spiardi, Ryan / Goldfarb, David S / Tasian, Gregory E

    European urology focus

    2023  Volume 9, Issue 6, Page(s) 866–868

    Abstract: Kidney stones are rising in incidence and prevalence worldwide. Given the temperature dependence of kidney stone presentations, climate change is projected to further increase the burden of disease for individuals and society. PATIENT SUMMARY: This mini- ... ...

    Abstract Kidney stones are rising in incidence and prevalence worldwide. Given the temperature dependence of kidney stone presentations, climate change is projected to further increase the burden of disease for individuals and society. PATIENT SUMMARY: This mini-review reports current knowledge on climate change in relation to kidney stone disease. Kidney stones are more common in patients living in parts of the world that are hotter and more humid. Kidney stone problems are also more common after periods of high heat, which have a greater impact on men than on women. As temperatures rise with climate change, it is likely that the occurrence of kidney stones and the costs associated with their diagnosis and treatment will increase as well.
    MeSH term(s) Male ; Humans ; Female ; Climate Change ; Kidney Calculi/epidemiology ; Kidney Calculi/etiology ; Kidney Calculi/diagnosis ; Hot Temperature ; Incidence ; Costs and Cost Analysis
    Language English
    Publishing date 2023-10-13
    Publishing country Netherlands
    Document type Journal Article ; Review ; Comment
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2023.10.001
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  3. Article ; Online: Measuring patient-centered outcomes: The need to move beyond quality of life.

    Tasian, Gregory E / Ellison, Jonathan S

    Journal of pediatric urology

    2021  Volume 17, Issue 4, Page(s) 444

    MeSH term(s) Humans ; Patient Satisfaction ; Patient-Centered Care ; Quality of Life
    Language English
    Publishing date 2021-04-03
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2021.03.033
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  4. Article ; Online: How We Treat Primary Hyperoxaluria Type 1.

    Breeggemann, Matthew C / Harris, Peter C / Lieske, John C / Tasian, Gregory E / Wood, Kyle D

    Clinical journal of the American Society of Nephrology : CJASN

    2024  

    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.0000000000000460
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  5. Article ; Online: The Surgical Improvement Cycle: Improving Surgical Outcomes through Partnerships and Rigor.

    Tasian, Gregory E / Ellison, Jonathan S

    The Journal of urology

    2021  Volume 205, Issue 6, Page(s) 1554–1556

    MeSH term(s) Humans ; Quality Control ; Treatment Outcome ; Urologic Diseases/surgery ; Urologic Surgical Procedures/standards
    Language English
    Publishing date 2021-01-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000001626
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  6. Article ; Online: Postoperative Recovery of Quality-of-Life Following Ureteroscopy for Nephrolithiasis: The Impact on Pain Intensity and Interference and the Ability to Participate in Social Roles.

    Ziemba, Justin B / Jones, Amanda / Lin, George / Stambakio, Hanna / Tasian, Gregory E / Huang, Jing

    Urology

    2024  

    Abstract: Objective: To prospectively capture patient-reported outcomes to assess the recovery profile of ureteroscopy (URS).: Materials and methods: Adults undergoing URS for renal/ureteral stones were eligible for inclusion (11/2020-8/2022). Patients ... ...

    Abstract Objective: To prospectively capture patient-reported outcomes to assess the recovery profile of ureteroscopy (URS).
    Materials and methods: Adults undergoing URS for renal/ureteral stones were eligible for inclusion (11/2020-8/2022). Patients prospectively completed PROMIS - Pain Intensity, - Pain Interference, and - Ability to participate in social roles and activities in-person preoperatively (POD 0) and via email on POD 1, 7, 14, and 30. Scores are reported as T-scores (normalized to U.S. population, mean=50) with a change of 5 (0.5 SD) considered clinically significant.
    Results: One hundred and seventy-eight participants enrolled at POD 0 (POD 1 =87, POD 7 =83, POD 14 =70, POD30 =67). There was a worsening of quality of life from day 0 to day 1 and day 0 to 7. All dimensions then improved with an increase in scores from day 0 to day 14 and day 0 to day 30. On multivariable analysis, the presence of a preoperative ureteral stent (OR 0.14) and use of semirigid URS (OR 0.33) were associated with a reduced odds for severe pain interference at day 1. The use of semirigid URS (OR 0.20) was associated with a reduced odds for severe worsening in the ability to participate in social roles at day 1.
    Conclusion: Ability to participate in social roles declines immediately postoperatively, while pain intensity and interference sharply increase. There is a gradual improvement until POD 30. Findings suggest preoperative stents may influence postoperative recovery. Results offer meaningful insight to assist in counseling and setting expectation for patients postoperatively.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2024.03.019
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  7. Article ; Online: Pediatric Stone Disease: Current Trends and Future Directions.

    Carmen Tong, Ching Man / Ellison, Jonathan S / Tasian, Gregory E

    The Urologic clinics of North America

    2023  Volume 50, Issue 3, Page(s) 465–475

    Abstract: Pediatric nephrolithiasis is less common in children than in adults but the incidence has been rising rapidly, and it is now a public health and economic burden in the United States. There are challenges unique to children that should be taken into ... ...

    Abstract Pediatric nephrolithiasis is less common in children than in adults but the incidence has been rising rapidly, and it is now a public health and economic burden in the United States. There are challenges unique to children that should be taken into consideration when evaluating and managing pediatric stone disease. In this review, we present the current research on risk factors, emerging new technologies for treatment of stones and recent investigations on prevention of stones in this population.
    MeSH term(s) Adult ; Humans ; Child ; Kidney Calculi/epidemiology ; Kidney Calculi/therapy ; Risk Factors
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 192293-2
    ISSN 1558-318X ; 0094-0143
    ISSN (online) 1558-318X
    ISSN 0094-0143
    DOI 10.1016/j.ucl.2023.04.009
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  8. Article: Pediatric Nephrolithiasis.

    Cao, Brent / Daniel, Roby / McGregor, Ryan / Tasian, Gregory E

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 4

    Abstract: The prevalence of pediatric nephrolithiasis has increased dramatically in the past two decades for reasons that have yet to be fully elucidated. Workup of pediatric kidney stones should include metabolic assessment to identify and address any risk ... ...

    Abstract The prevalence of pediatric nephrolithiasis has increased dramatically in the past two decades for reasons that have yet to be fully elucidated. Workup of pediatric kidney stones should include metabolic assessment to identify and address any risk factors predisposing patients to recurrent stone formation, and treatment should aim to facilitate stone clearance while minimizing complications, radiation and anesthetic exposure, and other risks. Treatment methods include observation and supportive therapy, medical expulsive therapy, and surgical intervention, with choice of treatment method determined by clinicians' assessments of stone size, location, anatomic factors, comorbidities, other risk factors, and preferences and goals of patients and their families. Much of the current research into nephrolithiasis is restricted to adult populations, and more data are needed to better understand many aspects of the epidemiology and treatment of pediatric kidney stones.
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11040552
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  9. Article ; Online: The Impact of Sex and Gender on Clinical Care and Research Design in Nephrolithiasis.

    Ellison, Jonathan S / Tasian, Gregory E

    Urology

    2020  Volume 151, Page(s) 54–57

    MeSH term(s) Female ; Humans ; Male ; Nephrolithiasis/therapy ; Research Design ; Sex Factors
    Language English
    Publishing date 2020-05-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2020.04.089
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  10. Article ; Online: Comparative effectiveness of high-power holmium laser lithotripsy for pediatric patients with kidney and ureteral stones.

    Harris, William N / Cao, Lusha / Tasian, Gregory E

    Journal of pediatric urology

    2022  Volume 18, Issue 4, Page(s) 463.e1–463.e8

    Abstract: Background: The comparative effectiveness of high-power laser technology for kidney stone surgery in pediatric patients is poorly understood. We compared outcomes for the 120 W Holmium:yttrium-aluminum-garnet (Ho:YAG) laser with MOSES technology to 30 W ...

    Abstract Background: The comparative effectiveness of high-power laser technology for kidney stone surgery in pediatric patients is poorly understood. We compared outcomes for the 120 W Holmium:yttrium-aluminum-garnet (Ho:YAG) laser with MOSES technology to 30 W Ho:YAG laser for pediatric patients undergoing ureteroscopy with laser lithotripsy for kidney and ureteral stones.
    Objective: We evaluated the outcomes of the new MOSES laser technology as compared to low-power Ho:YAG lasers commonly used for kidney stone treatment in the pediatric population.
    Methods: We performed a retrospective cohort study of 131 consecutive patients aged 1-18 years who underwent ureteroscopy and laser lithotripsy for renal and ureteric calculi at a large freestanding children's hospital between 2013 and 2020. The primary outcome was the efficiency quotient, which incorporates stone clearance, auxiliary procedures, and retreatment rates. Outcomes were compared between groups using Chi-square or Fisher's exact tests and multivariable regression. A sensitivity analysis was performed extending the age limit to ≤21 years.
    Results: Outcomes are summarized in the table below. Median age of the cohort was 14 years with 53% of patients being female. MOSES laser had a higher efficiency quotient and was associated with a lower odds of post-operative emergency department visits (OR 0.2, 95% CI 0.0-1.0; p = 0.047). Operative time was similar. In the sensitivity analysis of patients ≤21 years, the statistical significance with fewer emergency department visits was lost and the efficiency quotient was lower.
    Discussion: Our results show that stone clearance is similar between the 120 W MOSES and 30 W Ho:YAG lasers. However, there are indications that high-power laser lithotripsy is more efficient due to fewer auxiliary procedures and a reduction in retreatment. In addition, higher power lasers were associated with fewer emergency department visits. The benefits appear to be greater among children ≤18 years. These exploratory findings are important for pediatric patients due to the requirement for general anesthesia for each procedure and their associated impact on children and their caregivers.
    Conclusions: High-power laser lithotripsy may be more efficient than lower power laser lithotripsy, which is driven by the fewer auxiliary procedures and reduction in retreatment particularly among youth ≤18 years old.
    MeSH term(s) Adolescent ; Humans ; Child ; Female ; Male ; Lithotripsy, Laser/methods ; Holmium ; Lasers, Solid-State/therapeutic use ; Retrospective Studies ; Treatment Outcome ; Ureteral Calculi/surgery ; Lithotripsy/methods ; Ureteroscopy/methods ; Kidney Calculi/therapy ; Kidney
    Chemical Substances Holmium (W1XX32SQN1)
    Language English
    Publishing date 2022-06-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2022.05.022
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