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  1. Article ; Online: Identification of Polymorphisms in the

    Zhang, Xiaohui / Qi, Yanxia / Pang, Youzhi / Yuan, Bingjie / Li, Xiaolong

    The journal of poultry science

    2023  Volume 60, Issue 2, Page(s) 2023013

    Abstract: Mutations in ... ...

    Abstract Mutations in the
    Language English
    Publishing date 2023-05-25
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2197916-9
    ISSN 1349-0486 ; 1346-7395
    ISSN (online) 1349-0486
    ISSN 1346-7395
    DOI 10.2141/jpsa.2023013
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  2. Article ; Online: Adipokines in atopic dermatitis: the link between obesity and atopic dermatitis.

    Zhang, Shiyun / Zhang, Bingjie / Liu, Yuehua / Li, Li

    Lipids in health and disease

    2024  Volume 23, Issue 1, Page(s) 26

    Abstract: Atopic dermatitis (AD) is a chronic skin condition with intense pruritus, eczema, and dry skin. The recurrent intense pruritus and numerous complications in patients with AD can profoundly affect their quality of life. Obesity is one of its comorbidities ...

    Abstract Atopic dermatitis (AD) is a chronic skin condition with intense pruritus, eczema, and dry skin. The recurrent intense pruritus and numerous complications in patients with AD can profoundly affect their quality of life. Obesity is one of its comorbidities that has been confirmed to be the hazard factor of AD and also worsen its severity. Nevertheless, the specific mechanisms that explain the connection between obesity and AD remain incompletely recognized. Recent studies have built hopes on various adipokines to explain this connection. Adipokines, which are disturbed by an obese state, may lead to immune system imbalances in people with AD and promote the development of the disease. This review focuses on the abnormal expression patterns of adipokines in patients with AD and their potential regulatory molecular mechanisms associated with AD. The connection between AD and obesity is elucidated through the involvement of adipokines. This conduces to the in-depth exploration of AD pathogenesis and provides a new perspective to develop therapeutic targets.
    MeSH term(s) Humans ; Dermatitis, Atopic ; Quality of Life ; Obesity ; Pruritus ; Adipokines
    Chemical Substances Adipokines
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2091381-3
    ISSN 1476-511X ; 1476-511X
    ISSN (online) 1476-511X
    ISSN 1476-511X
    DOI 10.1186/s12944-024-02009-z
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  3. Article ; Online: Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report.

    Luo, Fuyi / Li, Bingjie / Li, Jing / Li, Yan

    Oncology letters

    2024  Volume 27, Issue 5, Page(s) 220

    Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare and aggressive tumor with an unknown pathogenesis. Myelofibrosis (MF) is a type of myeloproliferative neoplasm. MF can be secondary to several hematological malignancies, including ...

    Abstract Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare and aggressive tumor with an unknown pathogenesis. Myelofibrosis (MF) is a type of myeloproliferative neoplasm. MF can be secondary to several hematological malignancies, including chronic myeloid leukemia, myelodysplastic syndrome and hairy cell leukemia. In the present report, a rare case of BPDCN secondary to MF is described. A 70-year-old male patient developed a large purplish-red rash with recurrent symptoms. BPDCN was confirmed by immunohistochemistry of a biopsy specimen and flow cytometry of bone marrow cells. Bone marrow histopathology revealed MF. Next-generation sequencing of peripheral blood revealed mutations in the Tet methylcytosine dioxygenase 2 and NRAS proto-oncogene GTPase genes. The patient underwent one cycle of chemoimmunotherapy, but the condition progressed, an infection developed and the patient eventually died. The present case suggests that BPDCN can occur in conjunction with MF and that the prognosis of such patients is poor. Pathological examination and genetic testing aided in the diagnosis and treatment. This case emphasizes the need to raise awareness of BPDCN among clinicians and to be alert to the potential for fatal infection in patients with BPDCN combined with MF following myelosuppression triggered during chemotherapy.
    Language English
    Publishing date 2024-03-22
    Publishing country Greece
    Document type Case Reports
    ZDB-ID 2573196-8
    ISSN 1792-1082 ; 1792-1074
    ISSN (online) 1792-1082
    ISSN 1792-1074
    DOI 10.3892/ol.2024.14354
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  4. Article ; Online: Large and Pressure-Dependent

    Wang, Bingjie / Li, Juyao / Fang, Zheng / Jiang, Yifan / Li, Shuo / Zhan, Fangyuan / Dai, Zhaohe / Chen, Qing / Wei, Xianlong

    Nano letters

    2024  

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.4c00687
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  5. Article ; Online: RAB22A as a predictor of exosome secretion in the progression and relapse of multiple myeloma.

    Fan, Bingjie / Wang, Li / Wang, Jishi

    Aging

    2024  Volume 16, Issue 5, Page(s) 4169–4190

    Abstract: Background: Multiple myeloma (MM) is an incurable malignant plasma cell disease. We explored the role of RAB22A in exosome secretion, epithelial-mesenchymal transition (EMT) and immune regulation.: Methods: We obtained MM samples from Gene Expression ...

    Abstract Background: Multiple myeloma (MM) is an incurable malignant plasma cell disease. We explored the role of RAB22A in exosome secretion, epithelial-mesenchymal transition (EMT) and immune regulation.
    Methods: We obtained MM samples from Gene Expression Omnibus (GEO) data sets. We downloaded the "IOBR" package, and used the "PCA" and "ssGSEA" algorithms to calculate the EMT scores and exosome scores. The "CIBERSORT" package was used to analyze the infiltration of immune cells. We extracted the exosomes of mesenchymal stem cell (MSC) to verify the biological function of RAB22A.
    Results: The expression level of RAB22A in smoldering multiple myeloma (SMM) and MM patients was significantly higher than that in normal people and monoclonal gammopathy of undetermined significance (MGUS) patients, and the expression level of RAB22A in relapse MM patients was significantly higher than that in newly diagnosed patients. The EMT scores and exosome scores of high RAB22A group were significantly higher than those of low RAB22A group, and the exosome scores of MSC in recurrent patients were significantly higher than those of newly diagnosed patients. In addition, the infiltration levels of monocyte, NK cells resting, eosinophils, T cells regulatory and T cells CD4 memory activated were positively correlated with RAB22A. After down-regulating the expression of RAB22A in MM-MSC, the secretion of exosomes decreased. Compared with the exosomes of MSC in si-RAB22A group, the exosomes in control group significantly promoted the proliferation of MM.
    Conclusions: RAB22A is a potential therapeutic target to improve the prognosis of MM, which is closely related to exosome secretion, EMT and immune cell infiltration.
    MeSH term(s) Humans ; Multiple Myeloma/metabolism ; Exosomes/metabolism ; Prognosis ; Monoclonal Gammopathy of Undetermined Significance/diagnosis ; Monoclonal Gammopathy of Undetermined Significance/genetics ; Monoclonal Gammopathy of Undetermined Significance/metabolism ; Chronic Disease ; Recurrence ; Disease Progression ; rab GTP-Binding Proteins/genetics
    Chemical Substances RAB22A protein, human ; rab GTP-Binding Proteins (EC 3.6.5.2)
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.205565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: TaCRT3 Is a Positive Regulator of Resistance to

    Ren, Jun / Song, Panpan / Li, Ruobing / Wang, Qiao / Zhao, Bingjie / Wang, Baotong / Li, Qiang

    Phytopathology

    2024  Volume 114, Issue 3, Page(s) 641–652

    Abstract: Wheat powdery mildew, caused ... ...

    Abstract Wheat powdery mildew, caused by
    MeSH term(s) Plant Proteins/genetics ; Plant Proteins/metabolism ; Triticum/genetics ; Triticum/metabolism ; Disease Resistance/genetics ; Proteomics ; Hydrogen Peroxide/metabolism ; Plant Diseases/genetics ; Plant Breeding ; Ascomycota
    Chemical Substances Plant Proteins ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208889-7
    ISSN 1943-7684 ; 0031-949X
    ISSN (online) 1943-7684
    ISSN 0031-949X
    DOI 10.1094/PHYTO-08-23-0276-R
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  7. Article ; Online: Enhanced electrochemical performances based on ZnSnO

    Li, Xiaoqiang / Guan, Guangguang / Yu, Chuanjin / Cheng, Bingjie / Chen, Xin / Zhang, Kaiyin / Xiang, Jun

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 32, Page(s) 11187–11195

    Abstract: The binary composite, ... ...

    Abstract The binary composite, ZnSnO
    Language English
    Publishing date 2023-08-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt01642k
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  8. Article ; Online: Advances in protein-based microcapsules and their applications: A review.

    Ma, Donghui / Yang, Bingjie / Zhao, Jing / Yuan, Dongdong / Li, Quanhong

    International journal of biological macromolecules

    2024  Volume 263, Issue Pt 1, Page(s) 129742

    Abstract: Due to their excellent emulsification, biocompatibility, and biological activity, proteins are widely used as microcapsule wall materials for encapsulating drugs, natural bioactive substances, essential oils, probiotics, etc. In this review, we summarize ...

    Abstract Due to their excellent emulsification, biocompatibility, and biological activity, proteins are widely used as microcapsule wall materials for encapsulating drugs, natural bioactive substances, essential oils, probiotics, etc. In this review, we summarize the protein-based microcapsules, discussing the types of proteins utilized in microcapsule wall materials, the preparation process, and the main factors that influence their properties. Additionally, we conclude with examples of the vital role of protein-based microcapsules in advancing the food industry from primary processing to deep processing and their potential applications in the biomedical, chemical, and textile industries. However, the low stability and controllability of protein wall materials lead to degraded performance and quality of microcapsules. Protein complexes with polysaccharides or modifications to proteins are often used to improve the thermal instability, pH sensitivity, encapsulation efficiency and antioxidant capacity of microcapsules. In addition, factors such as wall material composition, wall material ratio, the ratio of core to wall material, pH, and preparation method all play critical roles in the preparation and performance of microcapsules. The application area and scope of protein-based microcapsules can be further expanded by optimizing the preparation process and studying the microcapsule release mechanism and control strategy.
    MeSH term(s) Capsules/chemistry ; Proteins ; Polysaccharides ; Oils, Volatile
    Chemical Substances Capsules ; Proteins ; Polysaccharides ; Oils, Volatile
    Language English
    Publishing date 2024-01-24
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.129742
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    Zs.B 2374: Show issues Location:
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  9. Article ; Online: The relationship between bullous pemphigoid and renal disease and related treatments: a review of the current literature.

    Cui, Shengnan / Zhang, Bingjie / Li, Li

    Expert review of clinical immunology

    2023  Volume 19, Issue 11, Page(s) 1407–1417

    Abstract: Introduction: Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disorder in older adults. There is increasing evidence that BP has connections with renal diseases, such as glomerulopathy and neoplasm; it is also linked to the ...

    Abstract Introduction: Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disorder in older adults. There is increasing evidence that BP has connections with renal diseases, such as glomerulopathy and neoplasm; it is also linked to the receipt of renal replacement therapy.
    Areas covered: In this review, we summarize the current evidence that BP is a comorbidity of common renal diseases. Furthermore, our exploration of the characteristics and possible mechanisms underlying these connections provides insights that may facilitate the prevention, diagnosis, and management of BP.
    Expert opinion: There is mounting proof that BP is not just a skin immunological disorder but rather a systemic immune-mediated illness. Quantities of case reports focused on BP as a renal disease comorbidity and the coexistence of them is not accidental. However, the underlying mechanisms are still needed to be investigated. Clinicians should be alert to the comorbidities in order to facilitate effective treatment and improve patient prognosis.
    MeSH term(s) Humans ; Aged ; Pemphigoid, Bullous/epidemiology ; Pemphigoid, Bullous/therapy ; Pemphigoid, Bullous/diagnosis ; Skin ; Comorbidity
    Language English
    Publishing date 2023-09-14
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2023.2249238
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  10. Article ; Online: Enhanced nitrate reduction in hypotrophic waters with integrated photocatalysis and biodegradation.

    Xue, Bingjie / Tian, Li / Liu, Yaqi / Peng, Lingxiu / Iqbal, Waheed / Li, Liangzhong / Mao, Yanping

    Environmental science and ecotechnology

    2024  Volume 21, Page(s) 100390

    Abstract: Addressing nitrate contamination in water bodies is a critical environmental challenge, and Intimately Coupling Photocatalysis and Biodegradation (ICPB) presents a promising solution. However, there is still debate about the effectiveness of ICPB in ... ...

    Abstract Addressing nitrate contamination in water bodies is a critical environmental challenge, and Intimately Coupling Photocatalysis and Biodegradation (ICPB) presents a promising solution. However, there is still debate about the effectiveness of ICPB in reducing nitrate under hypotrophic conditions. Further research is needed to understand its microbial metabolic mechanism and the functional changes in bacterial structure. Here we explored microbial metabolic mechanisms and changes in bacterial structure in ICPB reactors integrating a meticulously screened TiO
    Language English
    Publishing date 2024-01-13
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-4984
    ISSN (online) 2666-4984
    DOI 10.1016/j.ese.2024.100390
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