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  1. Article ; Online: H

    Jin, Ting / Lu, Hongyang / Zhou, Qiang / Chen, Dongfan / Zeng, Youyun / Shi, Jiayi / Zhang, Yanmei / Wang, Xianwen / Shen, Xinkun / Cai, Xiaojun

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2024  Volume 11, Issue 14, Page(s) e2308092

    Abstract: ... An innovative H ...

    Abstract Abnormal activation of the intestinal mucosal immune system, resulting from damage to the intestinal mucosal barrier and extensive invasion by pathogens, contributes to the pathogenesis of inflammatory bowel disease (IBD). Current first-line treatments for IBD have limited efficacy and significant side effects. An innovative H
    MeSH term(s) Humans ; Bentonite/metabolism ; Phosphatidylinositol 3-Kinases ; RNA, Ribosomal, 16S/metabolism ; Inflammatory Bowel Diseases/drug therapy ; Intestinal Mucosa
    Chemical Substances Bentonite (1302-78-9) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; RNA, Ribosomal, 16S
    Language English
    Publishing date 2024-02-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202308092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: H

    Li, Ying / Zeng, Houqing / Xu, Feiyun / Yan, Feng / Xu, Weifeng

    Annual review of plant biology

    2022  Volume 73, Page(s) 495–521

    Abstract: H ...

    Abstract H
    MeSH term(s) Membrane Potentials ; Proton-Motive Force ; Vacuolar Proton-Translocating ATPases/genetics ; Vacuolar Proton-Translocating ATPases/metabolism
    Chemical Substances Vacuolar Proton-Translocating ATPases (EC 3.6.1.-)
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2098209-4
    ISSN 1545-2123 ; 1543-5008
    ISSN (online) 1545-2123
    ISSN 1543-5008
    DOI 10.1146/annurev-arplant-102820-114551
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: H

    Lin, Yu-Chin / Zeng, Wan-Ting / Lee, Der-Yen

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Because hydrogen sulfide (H ...

    Abstract Because hydrogen sulfide (H
    MeSH term(s) Humans ; Glutathione Disulfide/metabolism ; HEK293 Cells ; Hydrogen Sulfide/pharmacology ; Hydrogen Sulfide/metabolism ; Insulin/metabolism ; Oxidation-Reduction ; Sulfides/metabolism
    Chemical Substances Glutathione Disulfide (ULW86O013H) ; Hydrogen Sulfide (YY9FVM7NSN) ; Insulin ; PTPN1 protein, human (EC 3.1.3.48) ; Sulfides
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: H

    Yin, Zhibin / Ji, Qian / Wu, Di / Li, Ziwei / Fan, Minfei / Zhang, Hongxin / Zhao, Xiaolong / Wu, Aiguo / Cheng, Liang / Zeng, Leyong

    ACS applied materials & interfaces

    2021  Volume 13, Issue 13, Page(s) 14928–14937

    Abstract: In order to achieve safe and high-efficient photodynamic therapy (PDT), it was a powerful strategy of constructing ... ...

    Abstract In order to achieve safe and high-efficient photodynamic therapy (PDT), it was a powerful strategy of constructing O
    MeSH term(s) Animals ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/drug therapy ; Cell Line, Tumor ; Female ; Gold/chemistry ; Gold/therapeutic use ; Humans ; Hydrogen Peroxide/metabolism ; Magnetic Resonance Imaging ; Manganese Compounds/chemistry ; Manganese Compounds/therapeutic use ; Mice ; Mice, Nude ; Nanoparticles/chemistry ; Nanoparticles/therapeutic use ; Oxides/chemistry ; Oxides/therapeutic use ; Photochemotherapy ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/therapeutic use
    Chemical Substances Manganese Compounds ; Oxides ; Photosensitizing Agents ; Gold (7440-57-5) ; Hydrogen Peroxide (BBX060AN9V) ; manganese dioxide (TF219GU161)
    Language English
    Publishing date 2021-03-24
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.1c00430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: H

    Deng, Qiang / Zhou, Rong / Zhang, Yong-Chao / Li, Xiang / Li, Jiahui / Tu, Shaobo / Sheng, Guan / Wang, Jun / Zeng, Zheling / Yoskamtorn, Tatchamapan / Edman Tsang, Shik Chi

    Angewandte Chemie (International ed. in English)

    2022  Volume 62, Issue 9, Page(s) e202211461

    Abstract: Currently, less favorable C=O hydrogenation and weak concerted acid catalysis cause unsatisfactory catalytic performance in the upgrading of biomass-derived furfurals (i.e., furfural, 5-methyl furfural, and 5-hydroxymethyl furfural) to ketones (i.e., ... ...

    Abstract Currently, less favorable C=O hydrogenation and weak concerted acid catalysis cause unsatisfactory catalytic performance in the upgrading of biomass-derived furfurals (i.e., furfural, 5-methyl furfural, and 5-hydroxymethyl furfural) to ketones (i.e., cyclopentanone, 2,5-hexanedione, and 1-hydroxyl-2,5-hexanedione). A series of partially oxidized MAX phase (i.e., Ti
    Language English
    Publishing date 2022-10-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202211461
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: H

    Zeng, Liping / Xu, Tianyi / Meng, Jie / Wu, Dingfang / Wu, Shihua

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 3

    Abstract: ... we presented a new insight that H ...

    Abstract Counter-current chromatography (CCC) is a unique liquid-liquid partition chromatography and largely relies on the partition interactions of solutes and solvents in two-phase solvents. Usually, the two-phase solvents used in CCC include a lipophilic organic phase and a hydrophilic aqueous phase. Although a large number of partition interactions have been found and used in the CCC separations, there are few studies that address the role of water on solvents and solutes in the two-phase partition. In this study, we presented a new insight that H
    MeSH term(s) Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Chromatography, Liquid/methods ; Hexanes/chemistry ; Hydrophobic and Hydrophilic Interactions ; Mass Spectrometry ; Methanol/chemistry ; Pyrans/chemistry ; Pyrans/isolation & purification ; Rubia/chemistry ; Solvents/chemistry ; Water/chemistry
    Chemical Substances Antineoplastic Agents ; Hexanes ; Pyrans ; Solvents ; Water (059QF0KO0R) ; rubimaillin (55481-88-4) ; Methanol (Y4S76JWI15)
    Language English
    Publishing date 2021-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26030751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: H

    Zhou, Meiling / Jiang, Nan / Fan, Junting / Fu, Song / Luo, Honghua / Su, Ping / Zhang, Mingwan / Shi, Huihui / Zeng, Jiaqi / Huang, Yuan / Li, Yang / Shen, Hong / Zhang, Aixia / Li, Rui

    Journal of controlled release : official journal of the Controlled Release Society

    2019  Volume 310, Page(s) 24–35

    Abstract: ... in vivo systemic delivery of siHDGF to gliomas. To address this question, we develop the peptide H ...

    Abstract The lack of effective glioma therapeutics mandates the development of novel treatment strategies. Hepatoma-derived growth factor (HDGF) has been considered as a potential glioma therapeutic target, and its expression level in gliomas is positively related to the malignant grade. Although there are no effective and specific inhibitors against this target, small interfering RNA targeting HDGF (siHDGF)-mediated RNA interference (RNAi) can inhibit the target protein function by knockdown of HDGF expression. However, the application of siHDGF in glioma research and therapy is hampered by the challenge to safe and effective in vivo systemic delivery of siHDGF to gliomas. To address this question, we develop the peptide H
    MeSH term(s) Animals ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Brain Neoplasms/therapy ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cell Survival/genetics ; Gene Transfer Techniques ; Glioma/metabolism ; Glioma/pathology ; Glioma/therapy ; Humans ; Hydrogen-Ion Concentration ; Intercellular Signaling Peptides and Proteins/genetics ; Mice, Nude ; Nanoparticles/chemistry ; Particle Size ; Peptides/chemistry ; Protein Stability ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/genetics ; RNA, Small Interfering/pharmacokinetics ; Tissue Distribution ; Transfection ; Xenograft Model Antitumor Assays
    Chemical Substances H7K(R2)2 peptide ; Intercellular Signaling Peptides and Proteins ; Peptides ; RNA, Small Interfering ; hepatoma-derived growth factor
    Language English
    Publishing date 2019-08-09
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632533-6
    ISSN 1873-4995 ; 0168-3659
    ISSN (online) 1873-4995
    ISSN 0168-3659
    DOI 10.1016/j.jconrel.2019.08.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: H

    Guo, Jin-Ming / Xing, Hou-Juan / Cai, Jing-Zeng / Zhang, Hong-Fu / Xu, Shi-Wen

    Ecotoxicology and environmental safety

    2020  Volume 209, Page(s) 111801

    Abstract: Hydrogen sulfide (H ...

    Abstract Hydrogen sulfide (H
    MeSH term(s) Animals ; Antioxidants/metabolism ; Autophagy/drug effects ; Catalase/metabolism ; Chickens/metabolism ; Glutathione Peroxidase/metabolism ; Hepatocytes/metabolism ; Hydrogen Sulfide/metabolism ; Hydrogen Sulfide/toxicity ; Lipopolysaccharides/metabolism ; Liver Diseases ; Oxidative Stress/physiology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Superoxide Dismutase/metabolism
    Chemical Substances Antioxidants ; Lipopolysaccharides ; Catalase (EC 1.11.1.6) ; Glutathione Peroxidase (EC 1.11.1.9) ; Superoxide Dismutase (EC 1.15.1.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Hydrogen Sulfide (YY9FVM7NSN)
    Language English
    Publishing date 2020-12-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 436536-7
    ISSN 1090-2414 ; 0147-6513
    ISSN (online) 1090-2414
    ISSN 0147-6513
    DOI 10.1016/j.ecoenv.2020.111801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: H

    Wu, Luyan / Ishigaki, Yusuke / Hu, Yuxuan / Sugimoto, Keisuke / Zeng, Wenhui / Harimoto, Takashi / Sun, Yidan / He, Jian / Suzuki, Takanori / Jiang, Xiqun / Chen, Hong-Yuan / Ye, Deju

    Nature communications

    2020  Volume 11, Issue 1, Page(s) 446

    Abstract: ... phenylenevinylene]) containing nanoparticles, developing an H ...

    Abstract Afterglow luminescent probes with high signal-to-background ratio show promise for in vivo imaging; however, such probes that can be selectively delivered into target sites and switch on afterglow luminescence remain limited. We optimize an organic electrochromic material and integrate it into near-infrared (NIR) photosensitizer (silicon 2,3-naphthalocyanine bis(trihexylsilyloxide) and (poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene]) containing nanoparticles, developing an H
    MeSH term(s) Animals ; Carcinoma, Hepatocellular/diagnostic imaging ; Colorectal Neoplasms/blood ; Cystathionine beta-Synthase/analysis ; Cystathionine beta-Synthase/metabolism ; Cystathionine gamma-Lyase/analysis ; Cystathionine gamma-Lyase/metabolism ; Hep G2 Cells ; Humans ; Hydrogen Sulfide/analysis ; Hydrogen Sulfide/blood ; Hydrogen Sulfide/chemistry ; Liver Neoplasms/blood ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms, Experimental/diagnostic imaging ; Luminescent Agents/chemical synthesis ; Luminescent Agents/chemistry ; Mice, Inbred BALB C ; Molecular Imaging/methods ; Nanoparticles/chemistry ; Photosensitizing Agents/chemistry ; Polymers/chemistry ; Vinyl Compounds/chemistry ; Xenograft Model Antitumor Assays
    Chemical Substances Luminescent Agents ; Photosensitizing Agents ; Polymers ; Vinyl Compounds ; poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) ; Cystathionine beta-Synthase (EC 4.2.1.22) ; Cystathionine gamma-Lyase (EC 4.4.1.1) ; Hydrogen Sulfide (YY9FVM7NSN)
    Language English
    Publishing date 2020-01-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-14307-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: H

    Zeng, Zhiwen / Wang, Dejun / Gaur, Uma / Rifang, Liao / Wang, Haitao / Zheng, Wenhua

    Oncotarget

    2017  Volume 8, Issue 39, Page(s) 65313–65328

    Abstract: ... in the development of neurodegeneration. In the present study, we investigated the effect of H ...

    Abstract Impairment of insulin-like growth factor I (IGF-I) signaling plays an important role in the development of neurodegeneration. In the present study, we investigated the effect of H
    Language English
    Publishing date 2017-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.18625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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