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  1. Book: Zhen jiu jia yi jing, Shang han lun, jin kui yao lue, Wen bing tiao bian jing yi

    Huang, Zhijie

    (Zhong yi jing dian ming zhu jing yi cong shu)

    1999  

    Title translation Modern translation of classical Chinese medicine books.
    Author's details zhu bian Huang Zhijie, Yao Changshou, Yu Xiaoping
    Series title Zhong yi jing dian ming zhu jing yi cong shu
    MeSH term(s) Medicine, Chinese Traditional
    Keywords China
    Language Chinese
    Size 18, 869 p.
    Publisher Ke xue ji shu wen xian chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787502332181 ; 7502332189
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article ; Online: Development of a colloidal gold immunochromatographic strip for rapid detection of avian coronavirus infectious bronchitis virus.

    Zhao, Chang-Run / Lin, Li-Ting / Tang, Jin-Wen / Zhang, Yu / Zhang, Wen / Chen, Ji-Ming / Wei, Ping / Huang, Teng / Wei, Tian-Chao / Mo, Mei-Lan

    Poultry science

    2024  Volume 103, Issue 6, Page(s) 103648

    Abstract: Avian infectious bronchitis virus (IBV) still causes serious economic losses in the poultry industry. Currently, there are multiple prevalent genotypes and serotypes of IBVs. It is imperative to develop a new diagnosis method that is fast, sensitive, ... ...

    Abstract Avian infectious bronchitis virus (IBV) still causes serious economic losses in the poultry industry. Currently, there are multiple prevalent genotypes and serotypes of IBVs. It is imperative to develop a new diagnosis method that is fast, sensitive, specific, simple, and broad-spectrum. A monoclonal hybridoma cell, N2D5, against the IBV N protein was obtained after fusion of myeloma SP2/0 cells with spleen cells isolated from the immunized Balb/c mice. The N2D5 monoclonal antibody (mAb) and the previously prepared mouse polyclonal antibody against the IBV N protein were used to target IBV as a colloidal gold-mAb conjugate and a captured antibody, respectively, in order to develop an immunochromatographic strip. The optimal pH and minimum antibody concentration in the reaction system for colloidal gold-mAb N2D5 conjugation were pH 6.5 and 30 μg/mL, respectively. Common avian pathogens were tested to evaluate the specificity of the strip and no cross-reaction was observed. The sensitivity of the strip for detecting IBV was 10
    Language English
    Publishing date 2024-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2024.103648
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Reactivity of cationic silver clusters with O

    Hu, Jin / Ma, Jun / Jin, Zhengqian / Liu, Wen / Huang, Lulu / Wang, Xuefeng / Xing, Xiaopeng

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 9, Page(s) 7407–7415

    Abstract: We explored the size-dependent reactivity of ... ...

    Abstract We explored the size-dependent reactivity of Ag
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp05082c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Role of SIRTs in cerebral ischemia reperfusion injury and targeted intervention of Chinese medicine].

    Huang, Guang-Shan / Wei, Xuan / Yang, Kai / Liu, Ji-Yong / Ge, Jin-Wen / Mei, Zhi-Gang

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2022  Volume 47, Issue 20, Page(s) 5406–5417

    Abstract: Cerebral ischemia-reperfusion injury(CIRI) is a complex cascade process and seriously hinders the recovery of patients with acute ischemic stroke, which has become an urgent public health issue to be addressed. Silent information regulators(SIRTs) are a ... ...

    Abstract Cerebral ischemia-reperfusion injury(CIRI) is a complex cascade process and seriously hinders the recovery of patients with acute ischemic stroke, which has become an urgent public health issue to be addressed. Silent information regulators(SIRTs) are a family of nicotinamide adenine dinucleotide(NAD~+)-dependent deacetylases, capable of deacylating the histone and non-histone lysine groups. Accumulating evidence has demonstrated that SIRTs are able to regulate the pathological processes such as oxidative stress, inflammatory response, mitochondrial dysfunction, and programmed cell death of CIRI through post-translational deacetylation, and exert the neuroprotection function. In this study, we reviewed the papers about the role and regulatory mechanisms of SIRTs in the pathological process of CIRI published in the past decade. Further, we summarized the research advance in the prevention and treatment of CIRI with Chinese medicine targeting SIRTs and the related signaling pathways. This review will provide new targets and theoretical support for the clinical application of Chinese medicine in treating CIRI during the occurrence of ischemic stroke.
    Language Chinese
    Publishing date 2022-12-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20220706.601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3056: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Improving Lead Phytoremediation Using Endophytic Bacteria Isolated from the Pioneer Plant

    Li, Qiqian / Yao, Siyu / Wen, Hua / Li, Wenqi / Jin, Ling / Huang, Xiuxiang

    Toxics

    2024  Volume 12, Issue 4

    Abstract: This study aimed to isolate and characterise endophytic bacteria from the pioneer ... ...

    Abstract This study aimed to isolate and characterise endophytic bacteria from the pioneer plant
    Language English
    Publishing date 2024-04-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2733883-6
    ISSN 2305-6304 ; 2305-6304
    ISSN (online) 2305-6304
    ISSN 2305-6304
    DOI 10.3390/toxics12040291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Anus preservation in low rectal adenocarcinoma based on MMR/MSI status (APRAM): a study protocol for a randomised, controlled, open-label, multicentre phase III trial.

    Huang, Cheng-Yi / Bai, Ming-Hua / Shen, Jin-Wen / Sun, Quan-Quan / Feng, Yan-Ru / Chen, Qian-Ping / Mao, Wei / Ju, Hai-Xing / Zhu, Ji

    BMC cancer

    2024  Volume 24, Issue 1, Page(s) 57

    Abstract: Background: Anus preservation has been a challenge in the treatment of patients with low rectal adenocarcinoma (within 5 cm from the anal verge) because it is difficult to spare the anus with its functioning sphincter complex under the safe margin of ... ...

    Abstract Background: Anus preservation has been a challenge in the treatment of patients with low rectal adenocarcinoma (within 5 cm from the anal verge) because it is difficult to spare the anus with its functioning sphincter complex under the safe margin of tumour resection. Patients with dMMR/MSI-H can achieve a favourable complete response (CR) rate by using a single immune checkpoint inhibitor. For patients with pMMR/MSS/MSI-L, intensified neoadjuvant three-drug chemotherapy may be the preferred option for anal preservation. In addition, the watch and wait (W&W) strategy has been proven safe and feasible for patients with rectal cancer who achieve a clinical complete response (cCR). Therefore, we initiated this clinical trial to explore the optimal neoadjuvant treatment pattern for patients with low locally advanced rectal cancer (LARC) with different MMR/MSI statuses, aiming to achieve a higher cCR rate with the W&W strategy and ultimately provide more patients with a chance of anus preservation.
    Methods: This is a randomised, controlled, open-label, multicentre phase III trial. Patients with clinical stage T2-4 and/or N + tumours located within 5 cm from the anal verge are considered eligible. Based on the results of pathological biopsy, the patients are divided into two groups: dMMR/MSI-H and pMMR/MSS. Patients in the dMMR/MSI-H group will be randomly allocated in a 1:1 ratio to either arm A (monoimmunotherapy) or arm B (short-course radiotherapy followed by monoimmunotherapy). Patients in the pMMR/MSS group will be initially treated with long-term pelvic radiation with concurrent capecitabine combined with irinotecan. Two weeks after the completion of chemoradiotherapy (CRT), the patients will be randomly allocated in a 1:1 ratio to arm C (XELIRI six cycle regime) or arm D (FOLFIRINOX nine cycle regime). The irinotecan dose will be adjusted according to the UGT1A1-genotype. After treatment, a comprehensive assessment will be performed to determine whether a cCR has been achieved. If achieved, the W&W strategy will be adopted; otherwise, total mesorectal excision (TME) will be performed. The primary endpoint is cCR with the maintenance of 12 months at least, determined using digital rectal examination, endoscopy, and rectal MRI or PET/CT as a supplementary method.
    Discussion: APRAM will explore the best anus preservation model for low LARC, combining the strategies of consolidation chemotherapy, immunotherapy, and short-course radiotherapy, and aims to preserve the anus of more patients using W&W. Our study provides an accurate individual treatment mode based on the MMR/MSI status for patients with low LARC, and more patients will receive the opportunity for anus preservation under our therapeutic strategy, which would transform into long-term benefits.
    Trial registration: Clinicaltrials.gov NCT05669092 (Registered 28th Nov 2022).
    MeSH term(s) Humans ; Anal Canal ; Antineoplastic Combined Chemotherapy Protocols ; Irinotecan ; Positron Emission Tomography Computed Tomography ; Pancreatic Neoplasms ; Rectal Neoplasms/drug therapy ; Rectal Neoplasms/genetics ; Adenocarcinoma/drug therapy ; Adenocarcinoma/genetics ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic ; Clinical Trials, Phase III as Topic ; Brain Neoplasms ; Neoplastic Syndromes, Hereditary ; Colorectal Neoplasms
    Chemical Substances Irinotecan (7673326042)
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-024-11829-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Biocontrol and Growth Promotion Potential of

    Huang, Ning / Jin, Xin / Wen, Jin-Tao / Zhang, Yi-Fei / Yang, Xu / Wei, Guang-Yu / Wang, Yi-Kun / Qin, Min

    Polish journal of microbiology

    2024  Volume 73, Issue 1, Page(s) 29–38

    Abstract: Fungal diseases form perforated disease spots in tobacco plants, resulting in a decline in tobacco yield and quality. The present study investigated the antagonistic effect ... ...

    Abstract Fungal diseases form perforated disease spots in tobacco plants, resulting in a decline in tobacco yield and quality. The present study investigated the antagonistic effect of
    MeSH term(s) Nicotiana ; Bacillus subtilis/genetics ; Disease Resistance ; Rhizoctonia
    Language English
    Publishing date 2024-03-04
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2234080-4
    ISSN 2544-4646 ; 1733-1331
    ISSN (online) 2544-4646
    ISSN 1733-1331
    DOI 10.33073/pjm-2024-004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Study on Microelectrochemical Inhomogeneity of an SA508-309

    Lai, Zhaogui / Huang, Feifei / Wen, Lei / Zhao, Zhaoyang / Jin, Ying

    Analytical chemistry

    2023  Volume 95, Issue 49, Page(s) 18006–18019

    Abstract: The corrosion behavior of the dissimilar metal welded joint (DMWJ) is highly dependent on its heterogeneous microstructures. However, directly measuring the electrochemical properties of microstructures in different heat-affected zones (HAZs) is a ... ...

    Abstract The corrosion behavior of the dissimilar metal welded joint (DMWJ) is highly dependent on its heterogeneous microstructures. However, directly measuring the electrochemical properties of microstructures in different heat-affected zones (HAZs) is a formidable challenge, because traditional bulk electrochemistry can only offer an average signal. Herein, the microelectrochemical properties of an SA508-309
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c02178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4033: Show issues Location:
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  9. Article: Preparation and Application of Directed Vat Set Indigenous Freeze-Drying

    Wang, Ling / Huang, Gang / Ma, Wen / Jin, Gang

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: In order to prepare a better direct vat set for malolactic fermentation (MLF) in high ethanol and low pH wines, the high-ethanol- and low-temperature-tolerant ... ...

    Abstract In order to prepare a better direct vat set for malolactic fermentation (MLF) in high ethanol and low pH wines, the high-ethanol- and low-temperature-tolerant strain
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12051053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Interleukin-22: a potential therapeutic target in atherosclerosis.

    Luo, Jin-Wen / Hu, Yuan / Liu, Jian / Yang, Huan / Huang, Peng

    Molecular medicine (Cambridge, Mass.)

    2021  Volume 27, Issue 1, Page(s) 88

    Abstract: Background: Atherosclerosis is recognized as a chronic immuno-inflammatory disease that is characterized by the accumulation of immune cells and lipids in the vascular wall. In this review, we focus on the latest advance regarding the regulation and ... ...

    Abstract Background: Atherosclerosis is recognized as a chronic immuno-inflammatory disease that is characterized by the accumulation of immune cells and lipids in the vascular wall. In this review, we focus on the latest advance regarding the regulation and signaling pathways of IL-22 and highlight its impacts on atherosclerosis.
    Main body: IL-22, an important member of the IL-10 family of cytokines, is released by cells of the adaptive and innate immune system and plays a key role in the development of inflammatory diseases. The binding of IL-22 to its receptor complex can trigger a diverse array of downstream signaling pathways, in particular the JAK/STAT, to induce the expression of chemokines and proinflammatory cytokines. Recently, numerous studies suggest that IL-22 is involved in the pathogenesis of atherosclerosis by regulation of VSMC proliferation and migration, angiogenesis, inflammatory response, hypertension, and cholesterol metabolism.
    Conclusion: IL-22 promotes the development of atherosclerosis by multiple mechanisms, which may be a promising therapeutic target in the pathogenesis of atherosclerosis.
    MeSH term(s) Animals ; Atherosclerosis/drug therapy ; Atherosclerosis/etiology ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Biomarkers ; Cytokines/metabolism ; Disease Management ; Disease Susceptibility ; Gene Expression Regulation ; Humans ; Inflammation Mediators/metabolism ; Interleukins/antagonists & inhibitors ; Interleukins/chemistry ; Interleukins/genetics ; Interleukins/metabolism ; Molecular Targeted Therapy ; Organ Specificity/genetics ; Protein Binding ; Receptors, Interleukin-21/metabolism ; Signal Transduction ; Structure-Activity Relationship ; Interleukin-22
    Chemical Substances Biomarkers ; Cytokines ; Inflammation Mediators ; Interleukins ; Receptors, Interleukin-21
    Language English
    Publishing date 2021-08-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1283676-x
    ISSN 1528-3658 ; 1076-1551
    ISSN (online) 1528-3658
    ISSN 1076-1551
    DOI 10.1186/s10020-021-00353-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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