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  1. Book ; Thesis: Validierung der Geriatric Depression Scale in einem Patientenkollektiv mit kognitiven Einschränkungen

    Koopmann, Anne

    2011  

    Author's details vorgelegt von Anne Koopmann
    Language German
    Size 103 Bl. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2012
    HBZ-ID HT017421423
    Database Catalogue ZB MED Medicine, Health

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    2012 E 1683 order for loan Magazin

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  2. Article ; Online: Forensische Aspekte der Verordnung medizinischen Cannabis in der Psychiatrie.

    Koopmann, Anne / Dreßing, Harald

    Der Nervenarzt

    2023  Volume 94, Issue 9, Page(s) 852–854

    Title translation Forensic aspects of prescribing medical cannabis in psychiatry.
    MeSH term(s) Humans ; Medical Marijuana/therapeutic use ; Psychiatry ; Forensic Psychiatry
    Chemical Substances Medical Marijuana
    Language German
    Publishing date 2023-08-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 123291-5
    ISSN 1433-0407 ; 0028-2804
    ISSN (online) 1433-0407
    ISSN 0028-2804
    DOI 10.1007/s00115-023-01529-w
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  3. Article: Rückfallprophylaxe bei Alkoholabhängigkeit

    Koopmann, Anne

    PSYCH up2date

    2020  Volume 14, Issue 04, Page(s) 307–322

    Language German
    Publishing date 2020-07-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2683337-2
    ISSN 2194-8909 ; 2194-8895
    ISSN (online) 2194-8909
    ISSN 2194-8895
    DOI 10.1055/a-0982-0730
    Database Thieme publisher's database

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  4. Article: Contrats thérapeutiques et traitements agonistes opioïdes : juridiquement et éthiquement discutables.

    Baud, Carole-Anne / Junod, Valérie / Beuriot, Stéphanie / Schmitt-Koopmann, Caroline / Andrade, Sara / Simon, Olivier

    Revue medicale suisse

    2023  Volume 19, Issue 830, Page(s) 1132–1135

    Abstract: In Switzerland, the use of « therapeutic contracts » in the implementation of opioid agonist treatments (OAT) is frequently recommended or even imposed. These documents raise legal and ethical issues, which are presented in this article. The authors ... ...

    Title translation Therapeutic contracts and opioid agonist treatments: legally and ethically questionable.
    Abstract In Switzerland, the use of « therapeutic contracts » in the implementation of opioid agonist treatments (OAT) is frequently recommended or even imposed. These documents raise legal and ethical issues, which are presented in this article. The authors recommend that this practice be abandoned. The usual tools of medical treatments (e.g. information document, treatment plan) are sufficient.
    MeSH term(s) Humans ; Analgesics, Opioid/therapeutic use ; Switzerland ; Opioid-Related Disorders/drug therapy ; Opiate Substitution Treatment
    Chemical Substances Analgesics, Opioid
    Language French
    Publishing date 2023-06-02
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2023.19.830.1132
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  5. Article: Switzerland's Dependence on a Diamorphine Monopoly.

    Schmitt-Koopmann, Caroline / Baud, Carole-Anne / Junod, Valérie / Simon, Olivier

    Frontiers in psychiatry

    2022  Volume 13, Page(s) 882299

    Abstract: In 2021, the manufacturer of diamorphine reported a possible impending shortage for Switzerland and Germany. This led us to investigate this controlled medicine's manufacture, market, and regulatory constraints. Based on our analysis of legal texts and ... ...

    Abstract In 2021, the manufacturer of diamorphine reported a possible impending shortage for Switzerland and Germany. This led us to investigate this controlled medicine's manufacture, market, and regulatory constraints. Based on our analysis of legal texts and gray literature in the form of reports and documents, we propose recommendations to prevent and address diamorphine shortages in Switzerland. Diamorphine, also known as pharmaceutical "heroin," is used medically to treat persons with severe opioid use disorder in a handful of countries. The controlled medicine is manufactured from morphine, which, in turn, is extracted from opium poppies. Studying data from the International Narcotics Control Board for 2019, we find that Switzerland accounts for almost half of the worldwide medical consumption of diamorphine. It manufactures more than half of the worldwide total and keeps the largest stocks. Moreover, Switzerland is dependent on a sole supplier of diamorphine (monopoly). As a niche product, diamorphine has an increased risk of shortage. Such a shortage would immediately threaten a valuable public health program for around 1,660 Swiss patients. We believe it is urgent to curtail the monopoly and ensure a stable supply for the future.
    Language English
    Publishing date 2022-05-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2022.882299
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  6. Article: The impact of COVID-19 pandemic on mental burden and quality of life in physicians: Results of an online survey.

    Wetzel, Lea / Halfmann, Marie / Castioni, Noah / Kiefer, Falk / König, Sarah / Schmieder, Astrid / Koopmann, Anne

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1068715

    Abstract: Background: In previous pan-/epidemics such as the SARS epidemic of 2002/2003, negative effects on the wellbeing and an increase in symptoms of depression and anxiety were observed in doctors due to social isolation and the threat they experienced. ... ...

    Abstract Background: In previous pan-/epidemics such as the SARS epidemic of 2002/2003, negative effects on the wellbeing and an increase in symptoms of depression and anxiety were observed in doctors due to social isolation and the threat they experienced. Therefore, it is feared that the COVID-19 pandemic will also have a negative impact on the mental health and quality of life of doctors.
    Objective: The impact of the COVID-19 pandemic on the mental health of physicians. In particular, on the subjective anxiety and burden, depression and quality of life for the total sample and subsamples (work in COVID-19 units vs. no work in COVID-19 units).
    Materials and methods: In an online survey, 107 physicians (23-42 years) were asked about their mental health during the COVID-19 pandemic. In addition to socio-demographic data, pandemic- and work-related data were also included. For example, infection control measures, deployment on COVID-19 wards and the subjective perceived threat posed by the pandemic. The physicians were asked to rate their perceived anxiety and stress, retrospectively, at 7 different points in time during the pandemic. The Hospital Anxiety and Depression Scale (HADS) was used to retrospectively assess symptoms of anxiety and depression before and after the onset of the pandemic. The quality of life of the participants after 2 years of the pandemic was assessed using the WHO Quality of Life (WHOQOL-BREF).
    Results: Both subjective anxiety and burden showed wave-like patterns with higher scores in autumn, winter and spring. We observed significant differences between the seven measurement time points for anxiety [Chi
    Conclusion: Hospitals should offer specific support, such as supervision, to prevent the development of longer-term psychiatric sequelae likely to lead to sick leave and high costs for the healthcare system.
    Trial registration: The study has been registered at the German Clinical Trials Registry (DRKS-ID: DRKS00028984).
    Language English
    Publishing date 2023-04-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1068715
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  7. Article: Effects of the COVID-19 pandemic on the mental health of medical students and young physicians in Germany: Gender-specific results of an online survey.

    Halfmann, Marie / Castioni, Noah / Wetzel, Lea / Koopmann, Anne / König, Sarah / Schmieder, Astrid

    Heliyon

    2023  Volume 10, Issue 1, Page(s) e23727

    Abstract: Background: Healthcare workers and medical students faced new challenges during the COVID-19 pandemic. Processes within many hospitals were completely disrupted. In addition, the face to face teaching of medical students was drastically reduced. Those ... ...

    Abstract Background: Healthcare workers and medical students faced new challenges during the COVID-19 pandemic. Processes within many hospitals were completely disrupted. In addition, the face to face teaching of medical students was drastically reduced. Those at risk of developing mental health problems appear to be younger health care workers and women.
    Objective: To investigate potential COVID-19 pandemic-related gender differences in psychological distress among medical students and physicians in their first years of practice.
    Design and setting: An anonymous survey was carried out online between December 1, 2021, and March 31, 2022, at the Mannheim Medical Faculty and the Würzburg Medical Faculty, Germany, after obtaining informed consent. Primary outcome measures were changes in anxiety and depression symptoms using the Hospital Anxiety and Depression Scale (HADS), and changes in participants' current quality of life using the WHO Quality of Life BREF.
    Results: The results show wave-like courses for perceived anxiety and burden overlapping with the course of the COVID-19 incidence. In comparison to men, women showed a significant higher increase in HADS (
    Conclusion: Future and young female physicians reported a disproportionate higher burden during COVID-19 compared to their male colleges. These observations suggest an increased need for support and prevention efforts especially in this vulnerable population.
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e23727
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  8. Article ; Online: The impact of COVID-19 pandemic on mental burden and quality of life in medical students - results of an online survey.

    Halfmann, Marie / Wetzel, Lea / Castioni, Noah / Kiefer, Falk / König, Sarah / Schmieder, Astrid / Koopmann, Anne

    GMS journal for medical education

    2023  Volume 40, Issue 2, Page(s) Doc21

    Abstract: Objectives: Changes in academic conditions due to the COVID-19 pandemic are potential stressors for medical students and can make them vulnerable for the development of psychiatric disorders.Previous pandemics had a negative impairment on well-being due ...

    Abstract Objectives: Changes in academic conditions due to the COVID-19 pandemic are potential stressors for medical students and can make them vulnerable for the development of psychiatric disorders.Previous pandemics had a negative impairment on well-being due to social isolation and the perceived threat, an increase in fear, anger and frustration and an increase in post-traumatic stress disorder among health professionals. Therefore, this study examines the impact of the COVID-19 pandemic on medical students' mental health and possible psychological consequences.
    Methods: In this anonymous online survey (online 12/01/2021-03/31/2022), we examined the impact of COVID-19 pandemic on mental health of 561 German medical students aged between 18 und 45 years. Perceived anxiety and burden were assessed retrospectively from spring 2020 to autumn 2021. Changes in symptoms of anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS), quality of life was assessed using the WHO Quality of Life Questionnaire (WHOQOL BREF).
    Results: Anxiety and burden showed wavelike courses with higher scores in autumn, winter and spring. The scores for depression and anxiety increased after the outbreak of the COVID-19 pandemic compared to the time before (p<.001). Results of a multifactorial ANOVA showed, that previous psychiatric illness (p<.001), being in the first two years of studies (p=.006), higher burden (p=.013) and greater differences in symptoms of depression (p<.001) were associated with a decreased quality of life in medical students.
    Conclusion: The COVID-19 pandemic has a negative impact on mental health of medical students and their actual quality of life. Therefore, medical faculties should establish specific support to prevent the development of psychiatric sequelae probably resulting in long-term medical leaves.
    MeSH term(s) Humans ; Adolescent ; COVID-19/epidemiology ; Pandemics ; Students, Medical ; Quality of Life ; Retrospective Studies ; SARS-CoV-2 ; Depression/epidemiology ; Depression/psychology ; Stress, Psychological/epidemiology ; Stress, Psychological/psychology ; Surveys and Questionnaires
    Language English
    Publishing date 2023-04-17
    Publishing country Germany
    Document type Journal Article
    ISSN 2366-5017
    ISSN (online) 2366-5017
    DOI 10.3205/zma001603
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  9. Article ; Online: Did the General Population in Germany Drink More Alcohol during the COVID-19 Pandemic Lockdown?

    Koopmann, Anne / Georgiadou, Ekaterini / Kiefer, Falk / Hillemacher, Thomas

    Alcohol and alcoholism (Oxford, Oxfordshire)

    2020  Volume 55, Issue 6, Page(s) 698–699

    MeSH term(s) Alcohol Drinking/epidemiology ; Alcoholism/epidemiology ; COVID-19 ; Coronavirus Infections ; Germany/epidemiology ; Humans ; Mental Health ; Pandemics ; Pneumonia, Viral ; Quarantine/psychology ; Surveys and Questionnaires
    Keywords covid19
    Language English
    Publishing date 2020-06-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 604956-4
    ISSN 1464-3502 ; 0309-1635 ; 0735-0414
    ISSN (online) 1464-3502
    ISSN 0309-1635 ; 0735-0414
    DOI 10.1093/alcalc/agaa058
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  10. Article ; Online: The Impact of Appetite-Regulating Neuropeptide Leptin on Alcohol Use, Alcohol Craving and Addictive Behavior: A Systematic Review of Preclinical and Clinical Data.

    Bach, Patrick / Koopmann, Anne / Kiefer, Falk

    Alcohol and alcoholism (Oxford, Oxfordshire)

    2020  Volume 56, Issue 2, Page(s) 149–165

    Abstract: Aims: The appetite regulating hormone leptin, which is mainly secreted from adipose tissue, is an important regulator of food intake and modulator of reward-driven behavior. Leptin exerts its biological actions via binding to the leptin receptor, which ... ...

    Abstract Aims: The appetite regulating hormone leptin, which is mainly secreted from adipose tissue, is an important regulator of food intake and modulator of reward-driven behavior. Leptin exerts its biological actions via binding to the leptin receptor, which is expressed in the hypothalamus, but also in the hippocampus, the amygdala and the substantia nigra. In the ventral tegmental area (VTA), leptin attenuates the firing rate of dopaminergic neurons that project to the Nucleus accumbens (NAc), which serves as relay to other brain areas of the "addiction network", such as the prefrontal cortex. This suggests that leptin plays a role in the processing of rewards in the context of substance use disorders such as alcohol use disorder, especially through attenuation of dopaminergic activity in the mesolimbic reward system. This supports the plausibility of leptin's potential effects in alcohol use disorder.
    Methods: We searched MEDLINE from 1990 to February 2020. All abstracts were screened for relevance and we only included publications reporting original data with a full text available in English language. Studies that did not report leptin-data, reviews or case reports/series were not included.
    Results: We identified a total of N=293 studies of whom a total of N=55 preclinical and clinical studies met the specified criteria. N=40 studies investigated the effects of alcohol on leptin plasma levels, N=9 studies investigated the effects of leptin on alcohol craving and N=6 studies investigated the effects of leptin on relapse and alcohol consumption.
    Conclusions: In this review of preclinical and clinical data, we assess the role of leptin in alcohol use and the development and maintenance of an alcohol use disorder, alcohol craving and relapse. Integrating the existing preclinical and clinical data on leptin may reveal new and innovative targets for the treatment of substance use disorders in the future.
    MeSH term(s) Alcohol Drinking/metabolism ; Animals ; Behavior, Addictive/metabolism ; Craving/physiology ; Dopaminergic Neurons/metabolism ; Female ; Humans ; Leptin/blood ; Leptin/metabolism ; Male ; Mice ; Nucleus Accumbens/metabolism ; Rats ; Ventral Tegmental Area/metabolism
    Chemical Substances Leptin
    Language English
    Publishing date 2020-06-02
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 604956-4
    ISSN 1464-3502 ; 0309-1635 ; 0735-0414
    ISSN (online) 1464-3502
    ISSN 0309-1635 ; 0735-0414
    DOI 10.1093/alcalc/agaa044
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